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C. Fontaine · SciRah

Researcher profile · Semantic Scholar

C. Fontaine

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C. Fontaine — researcher profile on SciRah

h-index: 38
Works: 113
Citations: 4,997

Most-cited papers

Membrane and Nuclear Estrogen Receptor Alpha Actions: From Tissue Specificity to Medical Implications.
J. Arnal, F. Lenfant, R. Métivier, G. Flouriot +7 more
2017Physiological Reviews352 citations
Semantic Scholar
Estrogen Receptors and Endometriosis
E. Chantalat, M. Valéra, C. Vaysse, E. Noirrit +8 more
2020International Journal of Molecular Sciences267 citations Open access
Semantic Scholar
Mutation of the palmitoylation site of estrogen receptor α in vivo reveals tissue-specific roles for membrane versus nuclear actions
Marine Adlanmerini, R. Solinhac, A. Abot, A. Fabre +16 more
2013Proceedings of the National Academy of Sciences of the United States of America232 citations Open access
Semantic Scholar
Estrogen receptors and endothelium.
J. Arnal, C. Fontaine, A. Billon-Galés, J. Favre +3 more
2010Arteriosclerosis, Thrombosis and Vascular Biology219 citations Open access
Semantic Scholar
Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha.
H. Duez, Jelske N. van der Veen, C. Duhem, B. Pourcet +11 more
2008Gastroenterology215 citations Open access
Semantic Scholar
Hedgehog Signaling Alters Adipocyte Maturation of Human Mesenchymal Stem Cells
C. Fontaine, W. Cousin, M. Plaisant, C. Dani +1 more
2008Stem Cells165 citations
Semantic Scholar
Liver X Receptor Activation Potentiates the Lipopolysaccharide Response in Human Macrophages
C. Fontaine, E. Rigamonti, A. Nohara, P. Gervois +4 more
2007Circulation Research142 citations
Semantic Scholar
Liver X Receptor Activation Controls Intracellular Cholesterol Trafficking and Esterification in Human Macrophages
E. Rigamonti, L. Helin, S. Lestavel, A. Mutka +9 more
2005Circulation Research142 citations Open access
Semantic Scholar
Activation function 2 (AF2) of estrogen receptor-α is required for the atheroprotective action of estradiol but not to accelerate endothelial healing
A. Billon-Galés, A. Krust, C. Fontaine, A. Abot +8 more
2011Proceedings of the National Academy of Sciences of the United States of America122 citations Open access
Semantic Scholar
Growth and Differentiation Factor 15 is secreted by skeletal muscle during exercise and promotes lipolysis in humans.
C. Laurens, A. Parmar, Enda E. Murphy, D. Carper +22 more
2020JCI Insight121 citations Open access
Semantic Scholar
The uterine and vascular actions of estetrol delineate a distinctive profile of estrogen receptor α modulation, uncoupling nuclear and membrane activation
A. Abot, C. Fontaine, Mélissa Buscato, R. Solinhac +25 more
2014EMBO Molecular Medicine116 citations Open access
Semantic Scholar
The transactivating function 1 of estrogen receptor α is dispensable for the vasculoprotective actions of 17β-estradiol
A. Billon-Galés, C. Fontaine, C. Filipe, V. Douin-Echinard +8 more
2009Proceedings of the National Academy of Sciences of the United States of America116 citations Open access
Semantic Scholar
Endothelial Estrogen Receptor-&agr; Plays a Crucial Role in the Atheroprotective Action of 17&bgr;-Estradiol in Low-Density Lipoprotein Receptor–Deficient Mice
A. Billon-Galés, C. Fontaine, V. Douin-Echinard, L. Delpy +7 more
2009Circulation106 citations Open access
Semantic Scholar
Activation of Hedgehog Signaling Inhibits Osteoblast Differentiation of Human Mesenchymal Stem Cells
M. Plaisant, C. Fontaine, W. Cousin, N. Rochet +2 more
2009Stem Cells98 citations
Semantic Scholar
The transactivating function-1 of estrogen receptor alpha is dispensable for the vasculoprotective actions of 17 beta-estradiol.
C. Fontaine, A. Billon-Galés, C. Filipe, V. Douin-Echinard +8 more
200973 citations
Semantic Scholar
The nuclear receptor Rev-erbalpha is a liver X receptor (LXR) target gene driving a negative feedback loop on select LXR-induced pathways in human macrophages.
C. Fontaine, E. Rigamonti, B. Pourcet, H. Duez +4 more
2008Molecular Endocrinology73 citations Open access
Semantic Scholar
Harnessing intestinal tryptophan catabolism to relieve atherosclerosis in mice
M. Chajadine, L. Laurans, T. Radecke, N. Mouttoulingam +19 more
2024Nature Communications72 citations Open access
Semantic Scholar
Profile of estetrol, a promising native estrogen for oral contraception and the relief of climacteric symptoms of menopause
C. Gérard, J. Arnal, M. Jost, J. Douxfils +10 more
2022Expert Review of Clinical Pharmacology71 citations Open access
Semantic Scholar
Hedgehog and adipogenesis: fat and fiction.
W. Cousin, C. Fontaine, C. Dani, P. Peraldi
2007Biochimie64 citations
Semantic Scholar
The AF-1 activation function of estrogen receptor α is necessary and sufficient for uterine epithelial cell proliferation in vivo.
A. Abot, C. Fontaine, I. Raymond-Letron, G. Flouriot +8 more
2013Endocrinology63 citations
Semantic Scholar
Increased Atherosclerotic Lesions in LDL Receptor Deficient Mice With Hematopoietic Nuclear Receptor Rev‐erbα Knock‐ Down
Hongling Ma, Wen-Bin Zhong, Yingliang Jiang, C. Fontaine +5 more
2013Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease61 citations Open access
Semantic Scholar
The AF-1-deficient estrogen receptor ERα46 isoform is frequently expressed in human breast tumors
E. Chantalat, Frédéric Boudou, H. Laurell, Gaëlle Palierne +12 more
2016Breast Cancer Research60 citations Open access
Semantic Scholar
Predominant Role of Nuclear Versus Membrane Estrogen Receptor α in Arterial Protection: Implications for Estrogen Receptor α Modulation in Cardiovascular Prevention/Safety
E. Guivarc'h, Mélissa Buscato, A. Guihot, J. Favre +16 more
2018Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease58 citations Open access
Semantic Scholar
Estrogen receptor subcellular localization and cardiometabolism
P. Gourdy, M. Guillaume, C. Fontaine, Marine Adlanmerini +4 more
2018Molecular Metabolism55 citations Open access
Semantic Scholar
The role of the orphan nuclear receptor Rev-Erbα in adipocyte differentiation and function
S. Laitinen, C. Fontaine, J. Fruchart, B. Staels
200554 citations
Semantic Scholar
Lessons from the dissection of the activation functions (AF-1 and AF-2) of the estrogen receptor alpha in vivo.
J. Arnal, C. Fontaine, A. Abot, M. Valéra +3 more
2013Steroids53 citations
Semantic Scholar
The Activation Function-1 of Estrogen Receptor Alpha Prevents Arterial Neointima Development Through a Direct Effect on Smooth Muscle Cells
Natalia F Smirnova, C. Fontaine, Mélissa Buscato, A. Lupieri +12 more
2015Circulation Research52 citations Open access
Semantic Scholar
Estrogen Receptor &agr; Expression in Both Endothelium and Hematopoietic Cells Is Required for the Accelerative Effect of Estradiol on Reendothelialization
C. Toutain, C. Filipe, A. Billon, C. Fontaine +5 more
2009Arteriosclerosis, Thrombosis and Vascular Biology51 citations Open access
Semantic Scholar
The orphan nuclear receptor Rev-erbα: a transcriptional link between circadian rhythmicity and cardiometabolic disease
C. Fontaine, B. Staels
2007Current Opinion in Lipidology42 citations
Semantic Scholar
Selective Liver Estrogen Receptor α Modulation Prevents Steatosis, Diabetes, and Obesity Through the Anorectic Growth Differentiation Factor 15 Hepatokine in Mice
M. Guillaume, Élodie Riant, A. Fabre, I. Raymond-Letron +15 more
2019Hepatology Communications40 citations Open access
Semantic Scholar
The Impact of Estrogen Receptor in Arterial and Lymphatic Vascular Diseases
C. Fontaine, F. Morfoisse, Florence Tatin, Audrey Zamora +5 more
2020International Journal of Molecular Sciences38 citations Open access
Semantic Scholar
Selective Activation of Estrogen Receptor α Activation Function-1 Is Sufficient to Prevent Obesity, Steatosis, and Insulin Resistance in Mouse.
M. Guillaume, S. Handgraaf, A. Fabre, I. Raymond-Letron +9 more
2017American Journal of Pathology38 citations Open access
Semantic Scholar
Effect of estetrol, a selective nuclear estrogen receptor modulator, in mouse models of arterial and venous thrombosis.
M. Valéra, E. Noirrit-Esclassan, Marion Dupuis, C. Fontaine +8 more
2018Molecular and Cellular Endocrinology37 citations
Semantic Scholar
Estetrol, a Fetal Selective Estrogen Receptor Modulator, Acts on the Vagina of Mice through Nuclear Estrogen Receptor α Activation.
T. Benoit, M. Valéra, C. Fontaine, Mélissa Buscato +7 more
2017American Journal of Pathology35 citations Open access
Semantic Scholar
Estradiol administration controls eosinophilia through estrogen receptor‐α activation during acute peritoneal inflammation
V. Douin-Echinard, B. Calippe, A. Billon-Galés, C. Fontaine +6 more
2011Journal of Leukocyte Biology35 citations Open access
Semantic Scholar
Tamoxifen elicits atheroprotection through estrogen receptor α AF-1 but does not accelerate reendothelialization.
C. Fontaine, A. Abot, A. Billon-Galés, G. Flouriot +6 more
2013American Journal of Pathology31 citations Open access
Semantic Scholar
Estrogen receptor actions on vascular biology and inflammation: implications in vascular pathophysiology
J. Arnal, H. Laurell, C. Fontaine, A. Billon +3 more
2009Climacteric30 citations
Semantic Scholar
Changes in Gene Expression and Estrogen Receptor Cistrome in Mouse Liver Upon Acute E2 Treatment.
Gaëlle Palierne, A. Fabre, R. Solinhac, Christine Le Péron +7 more
2016Molecular Endocrinology29 citations Open access
Semantic Scholar
The AF-1 activation function of estrogen receptor alpha is necessary and sufficient for uterine epithelial cell proliferation in vivo
A. Abot, C. Fontaine, P. Gourdy, F. Lenfant +1 more
201329 citations Open access
Semantic Scholar
Towards optimization of estrogen receptor modulation in medicine
M. Valéra, C. Fontaine, Marion Dupuis, E. Noirrit-Esclassan +5 more
2018Pharmacology and Therapeutics28 citations
Semantic Scholar
The role of the orphan nuclear receptor Rev-Erb alpha in adipocyte differentiation and function.
S. Laitinen, C. Fontaine, J. Fruchart, B. Staels
2005Biochimie28 citations
Semantic Scholar
Role of ERαMISS in the Effect of Estradiol on Cancellous and Cortical Femoral Bone in Growing Female Mice
Alexia Vinel, E. Hay, M. Valéra, Mélissa Buscato +7 more
2016Endocrinology27 citations
Semantic Scholar
Induction of CXCR2 Receptor by Peroxisome Proliferator-Activated Receptor &ggr; in Human Macrophages
E. Rigamonti, C. Fontaine, B. Lefebvre, C. Duhem +4 more
2008Arteriosclerosis, Thrombosis and Vascular Biology27 citations Open access
Semantic Scholar
Mutation of Arginine 264 on ERα (Estrogen Receptor Alpha) Selectively Abrogates the Rapid Signaling of Estradiol in the Endothelium Without Altering Fertility
Marine Adlanmerini, Chanaelle Fébrissy, R. Zahreddine, É. Vessieres +17 more
2020Arteriosclerosis, Thrombosis and Vascular Biology24 citations Open access
Semantic Scholar
Nuclear Activation Function 2 Estrogen Receptor α Attenuates Arterial and Renal Alterations Due to Aging and Hypertension in Female Mice
E. Guivarc'h, J. Favre, A. Guihot, É. Vessieres +11 more
2020Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease24 citations Open access
Semantic Scholar
Unique Vascular Benefits of Estetrol, a Native Fetal Estrogen with Specific Actions in Tissues (NEST)
J. Foidart, U. Gaspard, C. Péqueux, M. Jost +10 more
2019ISGE Series24 citations
Semantic Scholar
Tamoxifen Accelerates Endothelial Healing by Targeting ERα in Smooth Muscle Cells
R. Zahreddine, Morgane Davezac, N. Smirnova, Mélissa Buscato +14 more
2020Circulation Research21 citations Open access
Semantic Scholar
Membrane estrogen receptor alpha (ERα) participates in flow-mediated dilation in a ligand-independent manner
J. Favre, É. Vessieres, A. Guihot, C. Proux +16 more
2021eLife20 citations Open access
Semantic Scholar
From in vivo gene targeting of oestrogen receptors to optimization of their modulation in menopause
J. Arnal, F. Lenfant, G. Flouriot, F. Trémollières +5 more
2012British Journal of Pharmacology20 citations Open access
Semantic Scholar
Membrane estrogen receptor-α contributes to female protection against high-fat diet-induced metabolic disorders
Aurélie Fabre, B. Tramunt, A. Montagner, C. Mouly +8 more
2023Frontiers in Endocrinology19 citations Open access
Semantic Scholar

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