Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

J. Sygusch · SciRah

Researcher profile · Semantic Scholar

J. Sygusch

Share profile

J. Sygusch — researcher profile on SciRah

h-index: 34
Works: 178
Citations: 3,020

Most-cited papers

Crystal Structures of DNA-Whirly Complexes and Their Role in Arabidopsis Organelle Genome Repair[C][W]
L. Cappadocia, Alexandre Maréchal, Jean-Sébastien Parent, Étienne Lepage +2 more
2010The Plant Cell141 citations Open access
Semantic Scholar
Aldolase is essential for energy production and bridging adhesin-cytoskeletal interactions during parasite invasion of host cells
G. Starnes, M. Coincon, J. Sygusch, L. Sibley
2009Cell Host and Microbe109 citations Open access
Semantic Scholar
Structure-function profile of MmpL3, the essential mycolic acid transporter from Mycobacterium tuberculosis
J. Belardinelli, Amira Yazidi, Liang Yang, L. Fabre +7 more
2016ACS Infectious Diseases96 citations Open access
Semantic Scholar
Glycolytic and Non-glycolytic Functions of Mycobacterium tuberculosis Fructose-1,6-bisphosphate Aldolase, an Essential Enzyme Produced by Replicating and Non-replicating Bacilli*
M. de la Paz Santangelo, P. Gest, M. Guerin, M. Coincon +12 more
2011Journal of Biological Chemistry75 citations Open access
Semantic Scholar
Identification of the binding site of Brucella VirB8 interaction inhibitors.
M. Smith, M. Coincon, A. Paschos, Benoit Jolicoeur +3 more
2012Chemistry and Biology67 citations Open access
Semantic Scholar
Targeting a moonlighting function of aldolase induces apoptosis in cancer cells
A. Gizak, J. Wiśniewski, P. Heron, P. Mamczur +2 more
2019Cell Death and Disease62 citations Open access
Semantic Scholar
Crystal Structures of the Organomercurial Lyase MerB in Its Free and Mercury-bound Forms
J. Lafrance-Vanasse, M. Lefebvre, P. Di Lello, J. Sygusch +1 more
2009Journal of Biological Chemistry53 citations Open access
Semantic Scholar
Selective irreversible inhibition of fructose 1,6-bisphosphate aldolase from Trypanosoma brucei.
C. Dax, F. Duffieux, N. Chabot, M. Coincon +3 more
2006Journal of Medicinal Chemistry42 citations Open access
Semantic Scholar
MmpL3 as a Target for the Treatment of Drug-Resistant Nontuberculous Mycobacterial Infections
Wei Li, Amira Yazidi, Amit N. Pandya, Pooja V. Hegde +5 more
2018Frontiers in Microbiology41 citations Open access
Semantic Scholar
Structural Analysis and Inhibition of TraE from the pKM101 Type IV Secretion System*
B. Casu, J. Smart, Mark A. Hancock, Mark A. Smith +2 more
2016Journal of Biological Chemistry37 citations Open access
Semantic Scholar
Rational design, synthesis and evaluation of new selective inhibitors of microbial class II (zinc dependent) fructose bis-phosphate aldolases
Racha Daher, M. Coincon, M. Fonvielle, P. Gest +4 more
2010Journal of Medicinal Chemistry35 citations Open access
Semantic Scholar
Mechanism of Aldolase Control of Sorting Nexin 9 Function in Endocytosis*
E. Rangarajan, Hajeung Park, E. Fortin, J. Sygusch +1 more
2010Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Stereospecific Proton Transfer by a Mobile Catalyst in Mammalian Fructose-1,6-bisphosphate Aldolase*
M. St-jean, J. Sygusch
2007Journal of Biological Chemistry35 citations Open access
Semantic Scholar
Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics.
M. Fonvielle, M. Coincon, Racha Daher, N. Desbenoit +6 more
2008Chemistry34 citations
Semantic Scholar
A Hydrophobic Pocket in the Active Site of Glycolytic Aldolase Mediates Interactions with Wiskott-Aldrich Syndrome Protein*
M. St-jean, T. Izard, J. Sygusch
2007Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Active site remodeling during the catalytic cycle in metal-dependent fructose-1,6-bisphosphate aldolases
B. Jacques, M. Coincon, J. Sygusch
2018Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Peptides Designed To Spatially Depict the Epstein-Barr Virus Major Virion Glycoprotein gp350 Neutralization Epitope Elicit Antibodies That Block Virus-Neutralizing Antibody 72A1 Interaction with the Native gp350 Molecule
J. Tanner, M. Coincon, V. Leblond, Jing Hu +3 more
2015Journal of Virology27 citations Open access
Semantic Scholar
Structure of a Class I Tagatose-1,6-bisphosphate Aldolase
C. LowKam, B. Liotard, J. Sygusch
2010Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Crystal Structure of Reaction Intermediates in Pyruvate Class II Aldolase
M. Coincon, Weijun Wang, J. Sygusch, S. Seah
2012Journal of Biological Chemistry24 citations Open access
Semantic Scholar
Charge stabilization and entropy reduction of central lysine residues in fructose-bisphosphate aldolase.
M. St-jean, C. Blonski, J. Sygusch
2009Biochemistry24 citations
Semantic Scholar
A “drug sweeping” state of the TriABC triclosan efflux pump from Pseudomonas aeruginosa
L. Fabre, Abigail T. Ntreh, Amira Yazidi, I. V. Leus +6 more
2020Structure23 citations Open access
Semantic Scholar
Fragment-based screening identifies inhibitors of ATPase activity and of hexamer formation of Cagα from the Helicobacter pylori type IV secretion system
T. Arya, Flore Oudouhou, B. Casu, B. Bessette +2 more
2018Scientific Reports23 citations Open access
Semantic Scholar
A family portrait: structural comparison of the Whirly proteins from Arabidopsis thaliana and Solanum tuberosum.
L. Cappadocia, Jean-Sébastien Parent, J. Sygusch, N. Brisson
2013Acta Crystallographica. Section F : Structural Biology and Crystallization Communications22 citations Open access
Semantic Scholar
Analysis of Novel Interactions between Components of the Selenocysteine Biosynthesis Pathway, SEPHS1, SEPHS2, SEPSECS, and SECp43.
Flore Oudouhou, B. Casu, Arnold Steve Dopgwa Puemi, J. Sygusch +1 more
2017Biochemistry21 citations
Semantic Scholar
Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg-Carbon Bond Cleavage and Metal Binding Specificity.
H. M. Wahba, L. Lecoq, M. Stevenson, A. Mansour +6 more
2016Biochemistry19 citations
Semantic Scholar
Structural and Biochemical Characterization of Organotin and Organolead Compounds Binding to the Organomercurial Lyase MerB Provide New Insights into Its Mechanism of Carbon-Metal Bond Cleavage.
H. M. Wahba, M. Stevenson, A. Mansour, J. Sygusch +2 more
2017Journal of the American Chemical Society14 citations Open access
Semantic Scholar
Mannitol Bis-phosphate Based Inhibitors of Fructose 1,6-Bisphosphate Aldolases.
Charles-Gabin Mabiala-Bassiloua, G. Arthus-Cartier, V. Hannaert, H. Thérisod +2 more
2011ACS Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
Bisphosphonate Inhibitors of Mammalian Glycolytic Aldolase.
P. Heron, Marta Abellán-Flos, L. Salmon, J. Sygusch
2018Journal of Medicinal Chemistry11 citations
Semantic Scholar
Separate synthesis and evaluation of glucitol bis-phosphate and mannitol bis-phosphate, as competitive inhibitors of fructose bis-phosphate aldolases.
Charles-Gabin Mabiala-Bassiloua, Magdalena Zwolińska, H. Thérisod, J. Sygusch +1 more
2008Bioorganic & Medicinal Chemistry Letters11 citations
Semantic Scholar
Isomer activation controls stereospecificity of class I fructose-1,6-bisphosphate aldolases
P. Heron, J. Sygusch
2017Journal of Biological Chemistry8 citations Open access
Semantic Scholar
Three-Dimensional Architecture of the L-Type Calcium Channel: Structural Insights into the CaVÎ±2Î´1 Auxiliary Protein
J. Briot, Nazzareno D’Avanzo, J. Sygusch, L. Parent
20168 citations Open access
Semantic Scholar
Carboxy-terminus recruitment induced by substrate binding in eukaryotic fructose bis-phosphate aldolases.
J. Lafrance-Vanasse, J. Sygusch
2007Biochemistry7 citations
Semantic Scholar
Purification, crystallization and preliminary X-ray diffraction analysis of the Whirly domain of StWhy2 in complex with single-stranded DNA.
L. Cappadocia, J. Sygusch, N. Brisson
2008Acta Crystallographica. Section F : Structural Biology and Crystallization Communications6 citations Open access
Semantic Scholar
Structures of soluble rabbit neprilysin complexed with phosphoramidon or thiorphan.
S. Labiuk, J. Sygusch, P. Grochulski
2019Acta Crystallographica Section F Structural Biology Communications5 citations Open access
Semantic Scholar
GLYCOLYTIC AND NON-GLYCOLYTIC FUNCTIONS OF THE FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE OF MYCOBACTERIUM TUBERCULOSIS , AN ESSENTIAL ENZYME PRODUCED BY REPLICATING AND NON-REPLICATING
M. de la Paz Santangelo, P. Gest, M. Guerin, M. Coincon +12 more
20111 citations
Semantic Scholar
Dramatic improvement of crystal quality for low-temperature-grown rabbit muscle aldolase.
Hajeung Park, E. Rangarajan, J. Sygusch, T. Izard
2010Acta Crystallographica. Section F : Structural Biology and Crystallization Communications1 citations Open access
Semantic Scholar
1 STRUCTURE OF A CLASS I TAGATOSE-1 , 6-BIPHOSPHATE ALDOLASE : STUDY INTO AN APPARENT LOSS OF STEREOSPECIFICITY
C. LowKam, B. Liotard, J. Sygusch
20101 citations
Semantic Scholar
TriABC transporter from Pseudomonas aeruginosa
J. Sygusch, L. Fabre, I. Rouiller, S. Bhattacharyya
20200 citations
Semantic Scholar
Class II fructose-1,6-bisphosphate aldolase of Helicobacter pylori with DHAP
M. Coincon, J. Sygusch
20180 citations
Semantic Scholar
Class II fructose-1,6-bisphosphate aldolase E142A variant of Helicobacter pylori with FBP and cleavage products
B. Jacques, J. Sygusch
20180 citations
Semantic Scholar
Class II fructose-1,6-bisphosphate aldolase E142A variant of Helicobacter pylori with DHAP
B. Jacques, J. Sygusch
20180 citations
Semantic Scholar
Class II fructose-1,6-bisphosphate aldolase of Escherichia coli with D-glucitol 1,6-bisphosphate
M. Coincon, J. Sygusch
20180 citations
Semantic Scholar
Soluble rabbit neprilysin in complex with thiorphan
S. Labiuk, P. Grochulski, J. Sygusch
20180 citations
Semantic Scholar
Class II fructose-1,6-bisphosphate aldolase of Escherichia coli with DHAP
J. Sygusch, M. Coincon
20180 citations
Semantic Scholar
Crystal structure of FBP aldolase from Toxoplasma gondii, condensation intermediate
P. Heron, J. Sygusch
20170 citations
Semantic Scholar
Crystal structure of FBP aldolase from Toxoplasma gondii, Schiff base FBP complex
P. Heron, J. Sygusch
20170 citations
Semantic Scholar
Crystal structure of a MerB-triethyltin complex
H. M. Wahba, M. Stevenson, A. Mansour, J. Sygusch +2 more
20170 citations
Semantic Scholar
Crystal structure of FBP aldolase from Toxoplasma gondii, burst-phase ternary complex
P. Heron, J. Sygusch
20170 citations
Semantic Scholar
Crystal structure of FBP aldolase from Toxoplasma gondii, equilibrium Schiff base FBP complex
P. Heron, J. Sygusch
20170 citations
Semantic Scholar
Crystal structure of a the tin-bound form of MerB formed from Diethyltin.
H. M. Wahba, M. Stevenson, A. Mansour, J. Sygusch +2 more
20170 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

M. Coincon×13
Invite
M. Coincon — researcher profile on SciRah
P. Heron×7
Invite
P. Heron — researcher profile on SciRah
M. Jackson×6
Invite
M. Jackson — researcher profile on SciRah
M. Thérisod×6
Invite
M. Thérisod — researcher profile on SciRah

×5

Invite

J. Omichinski — researcher profile on SciRah

L. Cappadocia×4

Invite

L. Cappadocia — researcher profile on SciRah

Invite

B. Jacques — researcher profile on SciRah

Invite

Racha Daher — researcher profile on SciRah

Invite

C. Baron — researcher profile on SciRah

Invite

H. M. Wahba — researcher profile on SciRah

M. Stevenson×4

Invite

M. Stevenson — researcher profile on SciRah

Invite

D. Wilcox — researcher profile on SciRah