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Zao-Zhong Su · SciRah

Researcher profile · Semantic Scholar

Zao-Zhong Su

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Zao-Zhong Su — researcher profile on SciRah

h-index: 60
Works: 99
Citations: 10K

Most-cited papers

β-Lactam antibiotics offer neuroprotection by increasing glutamate transporter expression
J. Rothstein, S. Patel, M. R. Regan, Christine Haenggeli +11 more
2005Nature1,454 citations
Semantic Scholar
Subtraction hybridization identifies a novel melanoma differentiation associated gene, mda-7, modulated during human melanoma differentiation, growth and progression.
Hong-Ping Jiang, Jiao-Jiao Lin, Zao-Zhong Su, N. Goldstein +1 more
1995Oncogene521 citations
Semantic Scholar
Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression.
B. Yoo, Luni Emdad, Zao-Zhong Su, A. Villanueva +8 more
2009Journal of Clinical Investigation341 citations Open access
Semantic Scholar
Identification and cloning of human astrocyte genes displaying elevated expression after infection with HIV-1 or exposure to HIV-1 envelope glycoprotein by rapid subtraction hybridization, RaSH
Zao-Zhong Su, D. Kang, Yin-Ming Chen, Olga Pekarskaya +3 more
2002Oncogene334 citations Open access
Semantic Scholar
mda-7 (IL-24) mediates selective apoptosis in human melanoma cells by inducing the coordinated overexpression of the GADD family of genes by means of p38 MAPK
D. Sarkar, Zao-Zhong Su, I. Lebedeva, M. Sauane +4 more
2002Proceedings of the National Academy of Sciences of the United States of America332 citations Open access
Semantic Scholar
The melanoma differentiation associated gene mda-7 suppresses cancer cell growth.
Hong-Ping Jiang, Zao-Zhong Su, Jiao-Jiao Lin, Neil I. Goldstein +2 more
1996Proceedings of the National Academy of Sciences of the United States of America305 citations Open access
Semantic Scholar
Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1.
D. Kang, Zao-Zhong Su, D. Sarkar, Luni Emdad +2 more
2005Gene290 citations
Semantic Scholar
Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1.
D. Sarkar, E. Park, Luni Emdad, Seok-Geun Lee +2 more
2008Cancer Research247 citations
Semantic Scholar
Genomic structure, chromosomal localization and expression profile of a novel melanoma differentiation associated (mda-7) gene with cancer specific growth suppressing and apoptosis inducing properties
Eric Y. Huang, M. Madireddi, R. V. Gopalkrishnan, M. Leszczyniecka +17 more
2001Oncogene243 citations
Semantic Scholar
Activation of the Nuclear Factor κB Pathway by Astrocyte Elevated Gene-1: Implications for Tumor Progression and Metastasis
Luni Emdad, D. Sarkar, Zao-Zhong Su, A. Randolph +3 more
2006240 citations Open access
Semantic Scholar
Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc
Seok-Geun Lee, Zao-Zhong Su, Luni Emdad, D. Sarkar +1 more
2006Proceedings of the National Academy of Sciences of the United States of America230 citations Open access
Semantic Scholar
Insights into glutamate transport regulation in human astrocytes: Cloning of the promoter for excitatory amino acid transporter 2 (EAAT2)
Zao-Zhong Su, M. Leszczyniecka, D. Kang, D. Sarkar +3 more
2003Proceedings of the National Academy of Sciences of the United States of America207 citations Open access
Semantic Scholar
Functions of the cytoplasmic RNA sensors RIG-I and MDA-5: Key regulators of innate immunity
P. Barral, D. Sarkar, Zao-Zhong Su, G. Barber +3 more
2009Pharmacology and Therapeutics200 citations Open access
Semantic Scholar
mda-7/IL-24: multifunctional cancer-specific apoptosis-inducing cytokine.
P. Gupta, Zao-Zhong Su, I. Lebedeva, D. Sarkar +7 more
2006Pharmacology and Therapeutics185 citations Open access
Semantic Scholar
Melanoma differentiation associated gene-7, mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner
Zao-Zhong Su, I. Lebedeva, D. Sarkar, R. V. Gopalkrishnan +6 more
2003Oncogene178 citations
Semantic Scholar
The melanoma differentiation-associated gene mda-6, which encodes the cyclin-dependent kinase inhibitor p21, is differentially expressed during growth, differentiation and progression in human melanoma cells.
Hong-Ping Jiang, Jian Lin, Zao-Zhong Su, M. Herlyn +4 more
1995Oncogene167 citations
Semantic Scholar
MDA-7/IL-24: novel cancer growth suppressing and apoptosis inducing cytokine.
M. Sauane, R. V. Gopalkrishnan, D. Sarkar, Zao-Zhong Su +4 more
2003Cytokine & growth factor reviews164 citations
Semantic Scholar
Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis.
Luni Emdad, D. Sarkar, Zao-Zhong Su, A. Randolph +3 more
2006Cancer Research161 citations
Semantic Scholar
Astrocyte elevated gene-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration.
Luni Emdad, D. Sarkar, Zao-Zhong Su, Seok-Geun Lee +4 more
2007Pharmacology and Therapeutics160 citations Open access
Semantic Scholar
Identification of genes conferring resistance to 5-fluorouracil
B. Yoo, Rachel Gredler, Nicollaq Vozhilla, Zao-Zhong Su +7 more
2009Proceedings of the National Academy of Sciences of the United States of America150 citations Open access
Semantic Scholar
Surface-epitope masking and expression cloning identifies the human prostate carcinoma tumor antigen gene PCTA-1 a member of the galectin gene family.
Zao-Zhong Su, Jian Lin, R. Shen, P. Fisher +2 more
1996Proceedings of the National Academy of Sciences of the United States of America139 citations Open access
Semantic Scholar
Bcl-2 and Bcl-xL differentially protect human prostate cancer cells from induction of apoptosis by melanoma differentiation associated gene-7, mda-7/IL-24
I. Lebedeva, D. Sarkar, Zao-Zhong Su, S. Kitada +4 more
2003Oncogene137 citations
Semantic Scholar
Astrocyte Elevated Gene-1 (AEG-1): a multifunctional regulator of normal and abnormal physiology
B. Yoo, Luni Emdad, Seok-Geun Lee, Zao-Zhong Su +5 more
2011Pharmacology and Therapeutics136 citations Open access
Semantic Scholar
Autocrine regulation of mda-7/IL-24 mediates cancer-specific apoptosis
M. Sauane, Zao-Zhong Su, P. Gupta, I. Lebedeva +3 more
2008Proceedings of the National Academy of Sciences of the United States of America132 citations Open access
Semantic Scholar
BiP/GRP78 is an intracellular target for MDA-7/IL-24 induction of cancer-specific apoptosis.
P. Gupta, M. Walter, Zao-Zhong Su, I. Lebedeva +5 more
2006Cancer Research130 citations Open access
Semantic Scholar
Dual cancer-specific targeting strategy cures primary and distant breast carcinomas in nude mice.
D. Sarkar, Zao-Zhong Su, N. Vozhilla, E. Park +2 more
2005Proceedings of the National Academy of Sciences of the United States of America123 citations Open access
Semantic Scholar
Identification and cloning of human polynucleotide phosphorylase, hPNPaseold-35, in the context of terminal differentiation and cellular senescence
M. Leszczyniecka, D. Kang, D. Sarkar, Zao-Zhong Su +3 more
2002Proceedings of the National Academy of Sciences of the United States of America117 citations Open access
Semantic Scholar
Identification of the human prostatic carcinoma oncogene PTI-1 by rapid expression cloning and differential RNA display.
R. Shen, Zao-Zhong Su, Carl A. Olsson, Paul B. Fisher
1995Proceedings of the National Academy of Sciences of the United States of America116 citations Open access
Semantic Scholar
mda-9/Syntenin promotes metastasis in human melanoma cells by activating c-Src
H. Boukerche, Zao-Zhong Su, C. Prévôt, D. Sarkar +1 more
2008Proceedings of the National Academy of Sciences of the United States of America113 citations Open access
Semantic Scholar
Melanoma differentiation associated gene-7, mda-7/interleukin-24, induces apoptosis in prostate cancer cells by promoting mitochondrial dysfunction and inducing reactive oxygen species.
I. Lebedeva, Zao-Zhong Su, D. Sarkar, S. Kitada +4 more
2003Cancer Research112 citations
Semantic Scholar
mda-9/Syntenin: a positive regulator of melanoma metastasis.
H. Boukerche, Zao-Zhong Su, Luni Emdad, P. Baril +6 more
2005Cancer Research108 citations
Semantic Scholar
mda-7/IL-24, novel anticancer cytokine: focus on bystander antitumor, radiosensitization and antiangiogenic properties and overview of the phase I clinical experience (Review).
I. Lebedeva, Luni Emdad, Zao-Zhong Su, P. Gupta +27 more
2007International Journal of Oncology102 citations Open access
Semantic Scholar
mda-7 (IL-24) Inhibits Growth and Enhances Radiosensitivity of Glioma Cells In Vitro via JNK Signaling
A. Yacoub, Clint Mitchell, I. Lebedeva, D. Sarkar +6 more
2003Cancer Biology & Therapy102 citations Open access
Semantic Scholar
Mda-7, a novel melanoma differentiation associated gene with promise for cancer gene therapy.
M. Madireddi, Zao-Zhong Su, C. S. Young, Neil I. Goldstein +1 more
2000Advances in Experimental Medicine and Biology101 citations
Semantic Scholar
Astrocyte elevated gene-1: far more than just a gene regulated in astrocytes.
D. Sarkar, Luni Emdad, Seok-Geun Lee, B. Yoo +2 more
2009Cancer Research100 citations Open access
Semantic Scholar
Melanoma differentiation associated gene-7/interleukin-24 promotes tumor cell-specific apoptosis through both secretory and nonsecretory pathways.
M. Sauane, I. Lebedeva, Zao-Zhong Su, Heng-tong Choo +5 more
2004Cancer Research93 citations Open access
Semantic Scholar
Melanoma differentiation associated gene-7/interleukin-24 (mda-7/IL-24): novel gene therapeutic for metastatic melanoma.
P. Fisher, D. Sarkar, I. Lebedeva, Luni Emdad +8 more
2007Toxicology and Applied Pharmacology89 citations Open access
Semantic Scholar
Cloning and characterization of SARI (suppressor of AP-1, regulated by IFN)
Zao-Zhong Su, Seok-Geun Lee, Luni Emdad, Irina V. Lebdeva +4 more
2008Proceedings of the National Academy of Sciences of the United States of America87 citations Open access
Semantic Scholar
Customized rapid subtraction hybridization (RaSH) gene microarrays identify overlapping expression changes in human fetal astrocytes resulting from human immunodeficiency virus-1 infection or tumor necrosis factor-alpha treatment.
Zao-Zhong Su, Yin-Ming Chen, D. Kang, Wei Chao +3 more
2003Gene86 citations
Semantic Scholar
mda-9/Syntenin regulates the metastatic phenotype in human melanoma cells by activating nuclear factor-kappaB.
H. Boukerche, Zao-Zhong Su, Luni Emdad, D. Sarkar +1 more
2007Cancer Research85 citations
Semantic Scholar
mda-7 (IL-24): signaling and functional roles.
D. Sarkar, Zao-Zhong Su, I. Lebedeva, M. Sauane +3 more
2002BioTechniques84 citations Open access
Semantic Scholar
Subtraction hybridization identifies a transformation progression-associated gene PEG-3 with sequence homology to a growth arrest and DNA damage-inducible gene.
Zao-Zhong Su, Yi-Jie Shi, P. Fisher
1997Proceedings of the National Academy of Sciences of the United States of America84 citations Open access
Semantic Scholar
Insulin-like Growth Factor–Binding Protein-7 Functions as a Potential Tumor Suppressor in Hepatocellular Carcinoma
Dong Chen, B. Yoo, P. Santhekadur, Rachel Gredler +6 more
2011Clinical Cancer Research82 citations Open access
Semantic Scholar
Eradication of therapy-resistant human prostate tumors using a cancer terminator virus.
D. Sarkar, I. Lebedeva, Zao-Zhong Su, E. Park +5 more
2007Cancer Research81 citations Open access
Semantic Scholar
Effects of human immunodeficiency virus type 1 on astrocyte gene expression and function: Potential role in neuropathogenesis
Zhu-Ying Wang, G. Trillo-Pazos, Seon-Young Kim, M. Canki +8 more
2011Journal of Neurovirology80 citations
Semantic Scholar
Transcription factor Late SV40 Factor (LSF) functions as an oncogene in hepatocellular carcinoma
B. Yoo, Luni Emdad, Rachel Gredler, C. Fuller +9 more
2010Proceedings of the National Academy of Sciences of the United States of America79 citations Open access
Semantic Scholar
Growth suppression and toxicity induced by caffeic acid phenethyl ester (CAPE) in type 5 adenovirus-transformed rat embryo cells correlate directly with transformation progression.
Zao-Zhong Su, Jian Lin, Dezider Grunberger, Paul B. Fisher
1994Cancer Research78 citations
Semantic Scholar
Induction of reactive oxygen species renders mutant and wild-type K-ras pancreatic carcinoma cells susceptible to Ad.mda-7-induced apoptosis
I. Lebedeva, Zao-Zhong Su, D. Sarkar, R. V. Gopalkrishnan +4 more
2005Oncogene76 citations
Semantic Scholar
Central role of interferon regulatory factor‐1 (IRF‐1) in controlling retinoic acid inducible gene‐I (RIG‐I) expression
Zao-Zhong Su, D. Sarkar, Luni Emdad, P. Barral +1 more
2007Journal of Cellular Physiology73 citations Open access
Semantic Scholar
Defining the critical gene expression changes associated with expression and suppression of the tumorigenic and metastatic phenotype in Ha-ras-transformed cloned rat embryo fibroblast cells.
Zao-Zhong Su, V. Austin, Stephen G. Zimmer, Paul B. Fisher
1993Oncogene71 citations
Semantic Scholar

Frequent co-authors

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P. Fisher×42
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P. Fisher — researcher profile on SciRah
D. Sarkar×35
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D. Sarkar — researcher profile on SciRah
Luni Emdad×18
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Luni Emdad — researcher profile on SciRah
I. Lebedeva×16
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I. Lebedeva — researcher profile on SciRah

×14

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P. Dent — researcher profile on SciRah

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M. Sauane — researcher profile on SciRah

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K. Valerie — researcher profile on SciRah

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D. Kang — researcher profile on SciRah

R. V. Gopalkrishnan×8

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R. V. Gopalkrishnan — researcher profile on SciRah

Seok-Geun Lee×7

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Seok-Geun Lee — researcher profile on SciRah

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P. Gupta — researcher profile on SciRah

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B. Yoo — researcher profile on SciRah