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C. Le Nouën · SciRah

Researcher profile · Semantic Scholar

C. Le Nouën

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C. Le Nouën — researcher profile on SciRah

h-index: 17
Works: 41
Citations: 1,349

Most-cited papers

Very virulent infectious bursal disease virus: reduced pathogenicity in a rare natural segment-B-reassorted isolate.
C. Le Nouën, G. Rivallan, D. Toquín, P. Darlu +7 more
2006Journal of General Virology136 citations Open access
Semantic Scholar
Respiratory Syncytial Virus Interferon Antagonist NS1 Protein Suppresses and Skews the Human T Lymphocyte Response
Shirin Munir, P. Hillyer, C. Le Nouën, U. Buchholz +3 more
2011PLoS Pathogens129 citations Open access
Semantic Scholar
Nonstructural Proteins 1 and 2 of Respiratory Syncytial Virus Suppress Maturation of Human Dendritic Cells
Shirin Munir, C. Le Nouën, Cindy Luongo, U. Buchholz +2 more
2008Journal of Virology129 citations Open access
Semantic Scholar
Attenuation of human respiratory syncytial virus by genome-scale codon-pair deoptimization
C. Le Nouën, Linda G. Brock, Cindy Luongo, T. McCarty +7 more
2014Proceedings of the National Academy of Sciences of the United States of America122 citations Open access
Semantic Scholar
Both Genome Segments Contribute to the Pathogenicity of Very Virulent Infectious Bursal Disease Virus
O. Escaffre, C. Le Nouën, M. Amelot, X. Ambroggio +6 more
2012Journal of Virology110 citations Open access
Semantic Scholar
Actin-Related Protein 2 (ARP2) and Virus-Induced Filopodia Facilitate Human Respiratory Syncytial Virus Spread
M. Mehedi, T. McCarty, S. Martin, C. Le Nouën +10 more
2016PLoS Pathogens75 citations Open access
Semantic Scholar
Different Domains of the RNA Polymerase of Infectious Bursal Disease Virus Contribute to Virulence
C. Le Nouën, D. Toquín, Hermann Müller, R. Raue +4 more
2012PLoS ONE71 citations Open access
Semantic Scholar
Infection and maturation of monocyte-derived human dendritic cells by human respiratory syncytial virus, human metapneumovirus, and human parainfluenza virus type 3
C. Le Nouën, Shirin Munir, Stéphanie Losq, C. Winter +7 more
2009Virology68 citations Open access
Semantic Scholar
A single intranasal dose of a live-attenuated parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in hamsters
Xue-Qiao Liu, Cindy Luongo, Y. Matsuoka, Hong-Su Park +14 more
2021Proceedings of the National Academy of Sciences of the United States of America59 citations Open access
Semantic Scholar
Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine is protective in monkeys
C. Le Nouën, Christine E. Nelson, Xue-Qiao Liu, Hong-Su Park +18 more
2022Cell50 citations Open access
Semantic Scholar
Genetic stability of genome-scale deoptimized RNA virus vaccine candidates under selective pressure
C. Le Nouën, T. McCarty, Michael Brown, M. Smith +12 more
2017Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Low CCR7-Mediated Migration of Human Monocyte Derived Dendritic Cells in Response to Human Respiratory Syncytial Virus and Human Metapneumovirus
C. Le Nouën, P. Hillyer, C. Winter, T. McCarty +3 more
2011PLoS Pathogens46 citations Open access
Semantic Scholar
Effects of Human Respiratory Syncytial Virus, Metapneumovirus, Parainfluenza Virus 3 and Influenza Virus on CD4+ T Cell Activation by Dendritic Cells
C. Le Nouën, P. Hillyer, Shirin Munir, C. Winter +5 more
2010PLoS ONE41 citations Open access
Semantic Scholar
Attenuation of Human Respiratory Viruses by Synonymous Genome Recoding
C. Le Nouën, P. Collins, U. Buchholz
2019Frontiers in Immunology36 citations Open access
Semantic Scholar
Human Metapneumovirus SH and G Glycoproteins Inhibit Macropinocytosis-Mediated Entry into Human Dendritic Cells and Reduce CD4+ T Cell Activation
C. Le Nouën, P. Hillyer, Linda G. Brock, C. Winter +3 more
2014Journal of Virology30 citations Open access
Semantic Scholar
Significance of the genetic relationships deduced from partial nucleotide sequencing of infectious bursal disease virus genome segments A or B
C. Le Nouën, G. Rivallan, D. Toquín, Nicolas Eterradossi
2005Archives of Virology28 citations
Semantic Scholar
Respiratory syncytial virus infection induces a subset of types I and III interferons in human dendritic cells
P. Hillyer, V. Mane, Aaron Chen, M. B. Dos Santos +10 more
2017Virology26 citations Open access
Semantic Scholar
A Parainfluenza Virus Vector Expressing the Respiratory Syncytial Virus (RSV) Prefusion F Protein Is More Effective than RSV for Boosting a Primary Immunization with RSV
B. Liang, Y. Matsuoka, C. Le Nouën, Xue-Qiao Liu +7 more
2020Journal of Virology16 citations Open access
Semantic Scholar
Intranasal respiratory syncytial virus vaccine attenuated by codon-pair deoptimization of seven open reading frames is genetically stable and elicits mucosal and systemic immunity and protection against challenge virus replication in hamsters
M. Levy, J. Chen, Jaclyn A. Kaiser, Hong-Su Park +5 more
2024PLoS Pathogens15 citations Open access
Semantic Scholar
IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques
Christine E. Nelson, Taylor W. Foreman, E. Fukutani, Keith D. Kauffman +22 more
2024PLoS Pathogens14 citations Open access
Semantic Scholar
Intranasal immunization with avian paramyxovirus type 3 expressing SARS-CoV-2 spike protein protects hamsters against SARS-CoV-2
Hong-Su Park, Y. Matsuoka, Cindy Luongo, Li-Juan Yang +14 more
2022npj Vaccines12 citations Open access
Semantic Scholar
Optimization of the Codon Pair Usage of Human Respiratory Syncytial Virus Paradoxically Resulted in Reduced Viral Replication In Vivo and Reduced Immunogenicity
C. Le Nouën, Cindy Luongo, Li-Juan Yang, S. Mueller +4 more
2019Journal of Virology12 citations Open access
Semantic Scholar
IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques
Christine E. Nelson, Taylor W. Foreman, Keith D. Kauffman, Shunsuke Sakai +18 more
2022bioRxiv11 citations Open access
Semantic Scholar
Mucosal prime-boost immunization with live murine pneumonia virus-vectored SARS-CoV-2 vaccine is protective in macaques
Ursula J. Buchholz, Jaclyn A. Kaiser, Christine E. Nelson, Xue-Qiao Liu +23 more
2023Research Square9 citations Open access
Semantic Scholar
Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters
Xue-Qiao Liu, Hong-Su Park, Y. Matsuoka, Celia Santos +10 more
2023PLoS Pathogens8 citations Open access
Semantic Scholar
Rescue of codon-pair deoptimized respiratory syncytial virus by the emergence of genomes with very large internal deletions that complemented replication
C. Le Nouën, T. McCarty, Li-Juan Yang, Michael Brown +3 more
2021Proceedings of the National Academy of Sciences of the United States of America8 citations Open access
Semantic Scholar
Reversion mutations in phosphoprotein P of a codon-pair-deoptimized human respiratory syncytial virus confer increased transcription, immunogenicity, and genetic stability without loss of attenuation
Jessica W. Chen, Li-Juan Yang, Celia Santos, S. Hassan +3 more
2021PLoS Pathogens7 citations Open access
Semantic Scholar
Lack of Activation Marker Induction and Chemokine Receptor Switch in Human Neonatal Myeloid Dendritic Cells in Response to Human Respiratory Syncytial Virus
C. Le Nouën, P. Hillyer, Eric A. Levenson, C. Martens +3 more
2019Journal of Virology7 citations Open access
Semantic Scholar
Human parainfluenza virus 3 vaccine candidates attenuated by codon-pair deoptimization are immunogenic and protective in hamsters
Sharmin Afroz, Sirle Saul, Jin Dai, S. Surman +10 more
2024Proceedings of the National Academy of Sciences of the United States of America6 citations
Semantic Scholar
Intranasal parainfluenza virus-vectored vaccine expressing SARS-CoV-2 spike protein of Delta or Omicron B.1.1.529 induces mucosal and systemic immunity and protects hamsters against homologous and heterologous challenge
Hong-Su Park, Yumiko Matsuoka, Celia Santos, Cindy Luongo +9 more
2024bioRxiv6 citations Open access
Semantic Scholar
Intranasal murine pneumonia virus-vectored SARS-CoV-2 vaccine induces mucosal and serum antibodies in macaques
Jaclyn A. Kaiser, Xue-Qiao Liu, Cindy Luongo, Yumiko Matsuoka +11 more
2023iScience6 citations Open access
Semantic Scholar
Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters
Xue-Qiao Liu, Hong-Su Park, Y. Matsuoka, Celia Santos +10 more
2022bioRxiv6 citations Open access
Semantic Scholar
Intranasal parainfluenza virus-vectored vaccine expressing SARS-CoV-2 spike protein of Delta or Omicron B.1.1.529 induces mucosal and systemic immunity and protects hamsters against homologous and heterologous challenge
Hong-Su Park, Yumiko Matsuoka, Celia Santos, Cindy Luongo +9 more
2025PLoS Pathogens4 citations Open access
Semantic Scholar
Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine candidate is protective in macaques
C. Le Nouën, Christine E. Nelson, Xue-Qiao Liu, Hong-Su Park +18 more
2022bioRxiv4 citations Open access
Semantic Scholar
Live human metapneumovirus vaccine candidates attenuated by temperature sensitivity mutations from human respiratory syncytial virus
Pramila Lamichhane, Li-Juan Yang, Celia Santos, Hong-Su Park +4 more
2026Journal of Virology1 citations Open access
Semantic Scholar
An amino acid insertion in the PHI loop of the VP2 capsid protein of serotype 1 infectious bursal disease virus deeply modifies its antigenicity and abrogates its propagation into B cells
C. Le Nouën, C. Courtillon, S. Soubies, Philip Cruz +8 more
2026Veterinary Research0 citations Open access
Semantic Scholar
Co-administration of intranasal parainfluenza virus vaccines expressing antigenically distinct SARS-CoV-2 S antigens elicits broad and durable immunity in hamsters
Hong-Su Park, Yumiko Matsuoka, Celia Santos, Eleanor F. Duncan +8 more
2026Journal of Virology0 citations Open access
Semantic Scholar
Co-administration of intranasal parainfluenza virus vaccines expressing antigenically distinct SARS-CoV-2 S antigens elicits broad and durable immunity in hamsters
Hong-Su Park, Yumiko Matsuoka, Celia Santos, Eleanor F. Duncan +8 more
2025bioRxiv0 citations
Semantic Scholar
Mucosal prime-boost immunization with live murine pneumonia virus-vectored SARS-CoV-2 vaccine is protective in macaques
Jaclyn A. Kaiser, Christine E. Nelson, Xue-Qiao Liu, Hong-Su Park +23 more
2024Nature Communications0 citations Open access
Semantic Scholar
VACCINS CANDIDATS POUR LE VIRUS RESPIRATOIRE SYNCYTIAL HUMAIN (VRS) AYANT DES PHÉNOTYPES ATTÉNUÉS
C. Le Nouën, J. BuchholzUrsula, L. CollinsPeter, Steffen Mueller
20180 citations
Semantic Scholar
Étude de l'épidémiologie moléculaire du segment B de l'avibinavirus de la bursite infectieuse aviaire et bases moléculaires de la virulence chez ce virus
C. Le Nouën
20060 citations
Semantic Scholar

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