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V. Kotoula · SciRah

Researcher profile · Semantic Scholar

V. Kotoula

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V. Kotoula — researcher profile on SciRah

h-index: 37
Works: 238
Citations: 6,643

Most-cited papers

Tumor PIK3CA Genotype and Prognosis in Early-Stage Breast Cancer: A Pooled Analysis of Individual Patient Data.
D. Zardavas, L. Te Marvelde, R. Milne, D. Fumagalli +28 more
2018Journal of Clinical Oncology113 citations Open access
Semantic Scholar
Randomized phase III clinical trial comparing the combination of capecitabine and oxaliplatin (CAPOX) with the combination of 5-fluorouracil, leucovorin and oxaliplatin (modified FOLFOX6) as adjuvant therapy in patients with operated high-risk stage II or stage III colorectal cancer
D. Pectasides, V. Karavasilis, G. Papaxoinis, Georgia Gourgioti +13 more
2015BMC Cancer53 citations Open access
Semantic Scholar
Prognostic implications of mismatch repair deficiency in patients with nonmetastatic colorectal and endometrial cancer
E. Fountzilas, V. Kotoula, G. Pentheroudakis, K. Manousou +19 more
2019ESMO Open50 citations Open access
Semantic Scholar
Prognostic Evaluation of Epidermal Growth Factor Receptor (EGFR) Genotype and Phenotype Parameters in Triple-negative Breast Cancers.
S. Levva, V. Kotoula, I. Kostopoulos, K. Manousou +17 more
2017Cancer Genomics & Proteomics45 citations Open access
Semantic Scholar
Multiplexed (18-Plex) Measurement of Signaling Targets and Cytotoxic T cells in Trastuzumab-treated Patients using Imaging Mass Cytometry
D. Carvajal-Hausdorf, Jonathan Patsenker, K. Stanton, F. Villarroel-Espíndola +9 more
2019Clinical Cancer Research44 citations Open access
Semantic Scholar
TP53 mutations and protein immunopositivity may predict for poor outcome but also for trastuzumab benefit in patients with early breast cancer treated in the adjuvant setting
G. Fountzilas, E. Giannoulatou, Z. Alexopoulou, F. Zagouri +20 more
2016OncoTarget37 citations Open access
Semantic Scholar
Prognostic impact of stromal and intratumoral CD3, CD8 and FOXP3 in adjuvantly treated breast cancer: do they add information over stromal tumor-infiltrating lymphocyte density?
T. Koletsa, V. Kotoula, G. Koliou, K. Manousou +22 more
2020Cancer Immunology and Immunotherapy30 citations
Semantic Scholar
Tumor Infiltrating Lymphocytes and CD8+ T Cell Subsets as Prognostic Markers in Patients with Surgically Treated Laryngeal Squamous Cell Carcinoma
K. Chatzopoulos, V. Kotoula, Kyriaki Manoussou, K. Markou +6 more
2019Head and Neck Pathology30 citations Open access
Semantic Scholar
MYC copy gain, chromosomal instability and PI3K activation as potential markers of unfavourable outcome in trastuzumab-treated patients with metastatic breast cancer
H. Gogas, V. Kotoula, Z. Alexopoulou, C. Christodoulou +16 more
2016Journal of Translational Medicine30 citations Open access
Semantic Scholar
Prevalent somatic BRCA1 mutations shape clinically relevant genomic patterns of nasopharyngeal carcinoma in Southeast Europe
G. Fountzilas, A. Psyrri, E. Giannoulatou, I. Tikas +19 more
2018International Journal of Cancer24 citations Open access
Semantic Scholar
Angiogenic and Antiangiogenic VEGFA Splice Variants in Colorectal Cancer: Prospective Retrospective Cohort Study in Patients Treated With Irinotecan-Based Chemotherapy and Bevacizumab.
G. Pentheroudakis, L. Mavroeidis, K. Papadopoulou, G. Koliou +17 more
2019Clinical colorectal cancer21 citations
Semantic Scholar
Genes associated with histopathologic features of triple negative breast tumors predict molecular subtypes
K. Purrington, D. Visscher, Chen Wang, D. Yannoukakos +27 more
2016Breast Cancer Research and Treatment21 citations Open access
Semantic Scholar
Prognostic significance of tumor genotypes and CD8+ infiltrates in stage I-III colorectal cancer
E. Fountzilas, V. Kotoula, I. Tikas, K. Manousou +17 more
2018OncoTarget20 citations Open access
Semantic Scholar
Protein expression patterns of cell cycle regulators in operable breast cancer
F. Zagouri, V. Kotoula, G. Kouvatseas, M. Sotiropoulou +20 more
2017PLoS ONE20 citations Open access
Semantic Scholar
Comparison of somatic variant detection algorithms using Ion Torrent targeted deep sequencing data
Qing Wang, V. Kotoula, Pei-Chen Hsu, K. Papadopoulou +3 more
2019BMC Medical Genomics19 citations Open access
Semantic Scholar
Mismatch repair deficiency and aberrations in the Notch and Hedgehog pathways are of prognostic value in patients with endometrial cancer
G. Polychronidou, V. Kotoula, K. Manousou, I. Kostopoulos +13 more
2018PLoS ONE18 citations Open access
Semantic Scholar
Genotyping and mRNA profiling reveal actionable molecular targets in biliary tract cancers.
K. Papadopoulou, S. Murray, K. Manousou, I. Tikas +10 more
2018American Journal of Cancer Research16 citations
Semantic Scholar
Towards tumor immunodiagnostics.
H. Kourea, V. Kotoula
2016Annals of Translational Medicine16 citations Open access
Semantic Scholar
Prothrombin complex concentrate in major bleeding associated with DOACs; an updated systematic review and meta-analysis
Ioannis Milioglou, I. Farmakis, Mandy Neudeker, Zeeshan Hussain +4 more
2021Journal of Thrombosis and Thrombolysis15 citations
Semantic Scholar
Genotyping KRAS and EGFR Mutations in Greek Patients With Non-small-cell Lung Cancer: Incidence, Significance and Implications for Treatment
H. Linardou, V. Kotoula, G. Kouvatseas, G. Mountzios +16 more
2019Cancer Genomics & Proteomics15 citations Open access
Semantic Scholar
Evaluation of the Insulin-like Growth Factor Receptor Pathway in Patients with Advanced Breast Cancer Treated with Trastuzumab
C. Christodoulou, G. Oikonomopoulos, G. Koliou, I. Kostopoulos +16 more
2018Cancer Genomics & Proteomics15 citations Open access
Semantic Scholar
The CpG island methylator phenotype is concordant between primary colorectal carcinoma and matched distant metastases
Stacey A. Cohen, Ming Yu, K. Baker, M. Redman +9 more
2017Clinical Epigenetics15 citations Open access
Semantic Scholar
Effects of TP53 and PIK3CA mutations in early breast cancer: a matter of co-mutation and tumor-infiltrating lymphocytes
V. Kotoula, V. Karavasilis, F. Zagouri, G. Kouvatseas +17 more
2016Breast Cancer Research and Treatment15 citations
Semantic Scholar
Opposite Prognostic Impact of Single PTEN-loss and PIK3CA Mutations in Early High-risk Breast Cancer
G. Lazaridis, V. Kotoula, E. Vrettou, I. Kostopoulos +16 more
2019Cancer Genomics & Proteomics14 citations Open access
Semantic Scholar
Bridging Cancer Biology with the Clinic: Comprehending and Exploiting IDH Gene Mutations in Gliomas
Ourania Romanidou, V. Kotoula, G. Fountzilas
2018Cancer Genomics & Proteomics14 citations Open access
Semantic Scholar
Evaluation of PD-L 1 Expression and Associated Tumor-In fi ltrating Lymphocytes in Laryngeal Squamous Cell Carcinoma
M. Vassilakopoulou, M. Avgeris, V. Velcheti, V. Kotoula +10 more
201614 citations
Semantic Scholar
Is There an Independent Role of TERT and NF1 in High Grade Gliomas?
E. Razis, V. Kotoula, G. Koliou, K. Papadopoulou +14 more
2019Translational Oncology13 citations Open access
Semantic Scholar
Crizotinib Failure in a TPM4-ALK-Rearranged Inflammatory Myofibroblastic Tumor With an Emerging ALK Kinase Domain Mutation.
Kalliopi Tsakiri, V. Kotoula, S. Lakis, Judith Müller +4 more
2017JCO Precision Oncology13 citations
Semantic Scholar
Multisite Tumor Sampling Reveals Extensive Heterogeneity of Tumor and Host Immune Response in Ovarian Cancer
S. Lakis, V. Kotoula, G. Koliou, I. Efstratiou +4 more
2020Cancer Genomics & Proteomics11 citations Open access
Semantic Scholar
Relapsed and De Novo Metastatic HER2‐positive Breast Cancer Treated With Trastuzumab: Tumor Genotypes and Clinical Measures Associated With Patient Outcome
V. Kotoula, Kalliopi Tsakiri, G. Koliou, G. Lazaridis +16 more
2019Clinical Breast Cancer11 citations
Semantic Scholar
AMALTHEA: Prospective, Single‐Arm Study of the Hellenic Cooperative Oncology Group (HeCOG) Evaluating Efficacy and Safety of First‐Line FOLFIRI + Aflibercept for 6 Months Followed by Aflibercept Maintenance in Patients With Metastatic Colorectal Cancer
G. Pentheroudakis, V. Kotoula, G. Koliou, V. Karavasilis +20 more
2018Clinical colorectal cancer11 citations
Semantic Scholar
Prognostic Subcellular Notch2, Notch3 and Jagged1 Localization Patterns in Early Triple-negative Breast Cancer.
T. Strati, V. Kotoula, I. Kostopoulos, K. Manousou +17 more
2017Anticancer Research11 citations Open access
Semantic Scholar
Interaction Between Beta-Catenin and EGFR Expression by Immunohistochemistry Identifies Prognostic Subgroups in Early High-risk Triple-negative Breast Cancer.
S. Lakis, S. Dimoudis, V. Kotoula, Z. Alexopoulou +15 more
2016Anticancer Research11 citations
Semantic Scholar
Association of Notch and Hedgehog Pathway Activation With Prognosis in Early-stage Colorectal Cancer
G. Rallis, T. Koletsa, Z. Saridaki, K. Manousou +19 more
2019Anticancer Research10 citations Open access
Semantic Scholar
Genetic mapping of pancreatic cancer by targeted next-generation sequencing in a cohort of patients managed with nab-paclitaxel-based chemotherapy or agents targeting the EGFR axis: a retrospective analysis of the Hellenic Cooperative Oncology Group (HeCOG)
G. Zarkavelis, V. Kotoula, Georgia-Angeliki Kolliou, K. Papadopoulou +16 more
2019ESMO Open10 citations Open access
Semantic Scholar
Tumor Infiltrating Lymphocytes Affect the Outcome of Patients with Operable Triple-Negative Breast Cancer in Combination with Mutated Amino Acid Classes
V. Kotoula, S. Lakis, I. Vlachos, E. Giannoulatou +17 more
2016PLoS ONE10 citations Open access
Semantic Scholar
Pathogenic BRCA1 mutations may be necessary but not sufficient for tissue genomic heterogeneity: Deep sequencing data from ovarian cancer patients.
V. Kotoula, S. Lakis, I. Tikas, E. Giannoulatou +9 more
2019Gynecologic Oncology9 citations
Semantic Scholar
Nationwide Real-World Data of Microsatellite Instability and/or Mismatch Repair Deficiency in Cancer: Prevalence and Testing Patterns
E. Fountzilas, T. Papadopoulos, E. Papadopoulou, C. Gouédard +26 more
2024Diagnostics8 citations Open access
Semantic Scholar
Correlation of MYC Gene and Protein Status With Breast Cancer Subtypes and Outcome of Patients Treated With Anthracycline‐Based Adjuvant Chemotherapy. Pooled Analysis of 2 Hellenic Cooperative Group Phase III Trials
A. Batistatou, V. Kotoula, Mattheos Bobos, G. Kouvatseas +17 more
2017Clinical Breast Cancer8 citations
Semantic Scholar
Genotype - phenotype associations in colorectal adenocarcinomas and their matched metastases.
K. Chatzopoulos, V. Kotoula, G. Koliou, E. Giannoulatou +13 more
2020Human Pathology7 citations
Semantic Scholar
Phase II study of panitumumab combined with capecitabine and oxaliplatin as first-line treatment in metastatic colorectal cancer patients: clinical results including extended tumor genotyping
G. Papaxoinis, V. Kotoula, E. Giannoulatou, G. Koliou +18 more
2018Medical Oncology7 citations
Semantic Scholar
Disease evolution and heterogeneity in bilateral breast cancer.
E. Fountzilas, V. Kotoula, F. Zagouri, E. Giannoulatou +15 more
2016American Journal of Cancer Research7 citations
Semantic Scholar
Androgen Receptor and PIM1 Expression in Tumor Tissue of Patients With Triple-negative Breast Cancer
A. Ntzifa, A. Strati, G. Koliou, F. Zagouri +11 more
2021Cancer Genomics & Proteomics6 citations Open access
Semantic Scholar
Prognostic Impact of Src, CDKN1B, and JAK2 Expression in Metastatic Breast Cancer Patients Treated with Trastuzumab
P. Economopoulou, V. Kotoula, G. Koliou, K. Papadopoulou +18 more
2019Translational Oncology6 citations Open access
Semantic Scholar
The fate of BRCA1-related germline mutations in triple-negative breast tumors.
V. Kotoula, F. Fostira, K. Papadopoulou, Paraskevi Apostolou +19 more
2017American Journal of Cancer Research6 citations
Semantic Scholar
Genetic Variation in the Vascular Endothelial Growth Factor (VEGFA) Gene at rs13207351 Is Associated with Overall Survival of Patients with Head and Neck Cancer
F. Dimitrakopoulos, G. Koliou, V. Kotoula, K. Papadopoulou +10 more
2021Cancers5 citations Open access
Semantic Scholar
Clinical Significance of Major Angiogenesis-Related Effectors in Patients with Metastatic Breast Cancer Treated with Trastuzumab-Based Regimens
H. Kourea, F. Dimitrakopoulos, G. Koliou, A. Batistatou +15 more
2021Cancer research and treatment : official journal of Korean Cancer Association5 citations Open access
Semantic Scholar
mRNA expression of specific HER ligands and their association with clinical outcome in patients with metastatic breast cancer treated with trastuzumab.
Vassiliki Rapti, E. Moirogiorgou, G. Koliou, K. Papadopoulou +21 more
2021Oncology Letters5 citations Open access
Semantic Scholar
Tumor Mutational Patterns and Infiltrating Lymphocyte Density in Young and Elderly Patients With Breast Cancer
A. Nikolaidi, V. Kotoula, G. Koliou, E. Giannoulatou +16 more
2020Cancer Genomics & Proteomics5 citations Open access
Semantic Scholar
Prognostic Biomarkers in Early-stage Gastric Adenocarcinoma Treated With Adjuvant Chemoradiotherapy
E. Pectasides, I. Chatzidakis, V. Kotoula, G. Koliou +9 more
2020Cancer Genomics & Proteomics5 citations Open access
Semantic Scholar

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