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J. van Adelsberg · SciRah

Researcher profile · Semantic Scholar

J. van Adelsberg

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J. van Adelsberg — researcher profile on SciRah

h-index: 32
Works: 72
Citations: 5,495

Most-cited papers

New insights into the genetic etiology of Alzheimer’s disease and related dementias
C. Bellenguez, F. Küçükali, I. Jansen, L. Kleineidam +496 more
2022Nature Genetics1,984 citations Open access
Semantic Scholar
Cardiac defects and renal failure in mice with targeted mutations in Pkd2
Guanqing Wu, G. Markowitz, Li Li, V. D'Agati +11 more
2000Nature Genetics392 citations
Semantic Scholar
Efficacy and safety of sarilumab monotherapy versus adalimumab monotherapy for the treatment of patients with active rheumatoid arthritis (MONARCH): a randomised, double-blind, parallel-group phase III trial
G. Burmester, Yong Lin, Rahul J. Patel, J. van Adelsberg +6 more
2016Annals of the Rheumatic Diseases271 citations Open access
Semantic Scholar
Sarilumab Plus Methotrexate in Patients With Active Rheumatoid Arthritis and Inadequate Response to Methotrexate: Results of a Phase III Study
M. Genovese, R. Fleischmann, A. Kivitz, M. Rell-Bakalarska +13 more
2015Arthritis & Rheumatology243 citations Open access
Semantic Scholar
Polycystin-1, the PKD1 gene product, is in a complex containing E-cadherin and the catenins.
Yong-Hong Huan, J. van Adelsberg
1999Journal of Clinical Investigation243 citations Open access
Semantic Scholar
Sarilumab, a fully human monoclonal antibody against IL-6Rα in patients with rheumatoid arthritis and an inadequate response to methotrexate: efficacy and safety results from the randomised SARIL-RA-MOBILITY Part A trial
T. Huizinga, R. Fleischmann, M. Jasson, A. Radin +6 more
2013Annals of the Rheumatic Diseases222 citations Open access
Semantic Scholar
Sarilumab and Nonbiologic Disease‐Modifying Antirheumatic Drugs in Patients With Active Rheumatoid Arthritis and Inadequate Response or Intolerance to Tumor Necrosis Factor Inhibitors
R. Fleischmann, J. van Adelsberg, Yong Lin, G. da Rocha Castelar-Pinheiro +6 more
2016Arthritis & Rheumatology186 citations Open access
Semantic Scholar
Montelukast improves symptoms of seasonal allergic rhinitis over a 4‐week treatment period
J. van Adelsberg, G. Philip, A. Pedinoff, E. Meltzer +3 more
2003Allergy. European Journal of Allergy and Clinical Immunology134 citations
Semantic Scholar
Polycystin-1 interacts with E-cadherin and the catenins--clues to the pathogenesis of cyst formation in ADPKD?
J. van Adelsberg
2000131 citations
Semantic Scholar
Carbon-dioxide-induced exocytotic insertion of H+ pumps in turtle-bladder luminal membrane: role of cell pH and calcium
Christopher Cannon, J. van Adelsberg, S. Kelly, Q. Al-Awqati
1985Nature126 citations
Semantic Scholar
Randomized controlled trial evaluating the clinical benefit of montelukast for treating spring seasonal allergic rhinitis.
J. van Adelsberg, G. Philip, C. Laforce, S. Weinstein +3 more
2003Annals of Allergy, Asthma & Immunology117 citations
Semantic Scholar
Regulation of cell pH by Ca+2-mediated exocytotic insertion of H+- ATPases
J. van Adelsberg, Qais al-Awqati
1986Journal of Cell Biology107 citations Open access
Semantic Scholar
An induced extracellular matrix protein reverses the polarity of band 3 in intercalated epithelial cells.
J. van Adelsberg, J. Edwards, J. Takito, Brian Kiss +1 more
1994Cell90 citations
Semantic Scholar
Onset and duration of protection against exercise-induced bronchoconstriction by a single oral dose of montelukast.
D. Pearlman, J. van Adelsberg, G. Philip, S. Tilles +5 more
2006Annals of Allergy, Asthma & Immunology84 citations
Semantic Scholar
Montelukast for treating fall allergic rhinitis: effect of pollen exposure in 3 studies.
P. Chervinsky, G. Philip, M. Malice, J. Bardelas +6 more
2004Annals of Allergy, Asthma & Immunology74 citations
Semantic Scholar
Polycystin expression is temporally and spatially regulated during renal development.
J. van Adelsberg, S. Chamberlain, V. D'Agati
1997American Journal of Physiology67 citations
Semantic Scholar
The PKD1 gene product
P. Harris, G. Germino, K. Klinger, G. Landes +1 more
1995Nature Medicine66 citations
Semantic Scholar
Safety, tolerability, and exploratory efficacy of montelukast in 6- to 24-month-old patients with asthma
J. van Adelsberg, J. Moy, Lynn X. Wei, C. Tozzi +2 more
2005Current Medical Research and Opinion65 citations
Semantic Scholar
The apical Cl/HCO3 exchanger of beta intercalated cells.
J. van Adelsberg, J. Edwards, Qais al-Awqati
1993Journal of Biological Chemistry61 citations Open access
Semantic Scholar
Clinical studies of the DP1 antagonist laropiprant in asthma and allergic rhinitis.
G. Philip, J. van Adelsberg, T. Loeys, Nancy Liu +4 more
2009Journal of Allergy and Clinical Immunology55 citations
Semantic Scholar
Systematic review of trials of the effect of continued use of oral non-selective NSAIDs on blood pressure and hypertension*
A. Morrison, Dena Rosen Ramey, J. van Adelsberg, D. Watson
2007Current Medical Research and Opinion55 citations
Semantic Scholar
Activation of Hepatocyte Growth Factor (HGF) by Endogenous HGF Activator Is Required for Metanephric Kidney Morphogenesis in Vitro *
J. van Adelsberg, Swati Sehgal, Andrew Kukes, C. Brady +3 more
2001Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Protection of perfused lung from oxidant injury by inhibitors of anion exchange.
Eva Nozik-Grayck, C. A. Piantadosi, J. van Adelsberg, Seth L. Alper +1 more
1997American Journal of Physiology52 citations
Semantic Scholar
Sarilumab plus methotrexate suppresses circulating biomarkers of bone resorption and synovial damage in patients with rheumatoid arthritis and inadequate response to methotrexate: a biomarker study of MOBILITY
Anita Boyapati, J. Msihid, S. Fiore, J. van Adelsberg +2 more
2016Arthritis Research & Therapy50 citations Open access
Semantic Scholar
Patient-reported outcomes from a randomized phase III trial of sarilumab monotherapy versus adalimumab monotherapy in patients with rheumatoid arthritis
V. Strand, L. Gossec, C. Proudfoot, Chieh-I Chen +8 more
2018Arthritis Research & Therapy47 citations Open access
Semantic Scholar
Pharmacokinetics of Montelukast in Asthmatic Patients 6 to 24 Months Old
E. Migoya, G. Kearns, A. Hartford, Jamie J. Zhao +4 more
2004Journal of clinical pharmacology45 citations
Semantic Scholar
Inherited myeloproliferative neoplasm risk affects haematopoietic stem cells
Erik L. Bao, Satish K. Nandakumar, Xiaotian Liao, A. Bick +335 more
2020Nature44 citations Open access
Semantic Scholar
Conditional immortalization of bicarbonate-secreting intercalated cells from rabbit.
J. Edwards, J. van Adelsberg, M. Rater, D. Herzlinger +2 more
1992American Journal of Physiology43 citations
Semantic Scholar
The PKD1 gene produces a developmentally regulated protein in mesenchyme and vasculature
J. van Adelsberg, Dale Frank
1995Nature Medicine42 citations
Semantic Scholar
Evaluation of the comparative efficacy and tolerability of rofecoxib and naproxen in children and adolescents with juvenile rheumatoid arthritis: a 12-week randomized controlled clinical trial with a 52-week open-label extension.
A. Reiff, D. Lovell, J. van Adelsberg, M. Kiss +7 more
2006Journal of Rheumatology41 citations
Semantic Scholar
Two years of sarilumab in patients with rheumatoid arthritis and an inadequate response to MTX: safety, efficacy and radiographic outcomes
M. Genovese, J. van Adelsberg, C. Fan, N. Graham +6 more
2018Rheumatology35 citations Open access
Semantic Scholar
The VIOXX in prostate cancer prevention study: cardiovascular events observed in the rofecoxib 25 mg and placebo treatment groups*
J. van Adelsberg, P. Gann, A. Ko, J. Damber +6 more
2007Current Medical Research and Opinion32 citations
Semantic Scholar
Peptides from the PKD repeats of polycystin, the PKD1 gene product, modulate pattern formation in the developing kidney.
J. van Adelsberg
199932 citations
Semantic Scholar
Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.
Laura M. C. Barisoni, M. Trudel, N. Chrétien, L. Ward +2 more
1995American Journal of Pathology29 citations
Semantic Scholar
The Effect of Apical and Basolateral Lipids on the Function of the Band 3 Anion Exchange Protein
W. Hof, Abha Malik, S. Vijayakumar, Jizeng Qiao +2 more
1997Journal of Cell Biology25 citations Open access
Semantic Scholar
Isolation and culture of HCO3- -secreting intercalated cells.
J. van Adelsberg, J. Edwards, D. Herzlinger, Christopher Cannon +2 more
1989American Journal of Physiology21 citations
Semantic Scholar
Daprodustat and Heart Failure in CKD
J. Cunningham, B. Claggett, R. Lopes, J. McMurray +10 more
2024Journal of the American Society of Nephrology18 citations Open access
Semantic Scholar
Murine polycystic kidney epithelial cell lines have increased integrin-mediated adhesion to collagen.
J. van Adelsberg
1994American Journal of Physiology17 citations
Semantic Scholar
Peptides from the PKD repeats of polycystin, the PKD1 gene product, modulate pattern formation in the developing kidney.
J. van Adelsberg
1999Developmental Genetics14 citations
Semantic Scholar
The role of the polycystins in kidney development
J. van Adelsberg
1999Pediatric nephrology (Berlin, West)14 citations
Semantic Scholar
Murine polycystic kidney epithelial cell lines have increased integrin-mediated adhesion to collagen
J. van Adelsberg
199414 citations
Semantic Scholar
The role of the polycystins in kidney development
J. van Adelsberg
1999Pediatric nephrology (Berlin, West)13 citations
Semantic Scholar
Polycystin-1 interacts with E-cadherin and the catenins--clues to the pathogenesis of cyst formation in ADPKD?
J. van Adelsberg
2000Nephrology, Dialysis and Transplantation10 citations
Semantic Scholar
Measurement of pH of intracellular compartments in living cells by fluorescent dyes.
J. van Adelsberg, Jonathan Barasch, Qais al-Awqati
1989Methods in Enzymology7 citations
Semantic Scholar
SAT0160 Clinical and Radiographic Outcomes after 2 Years of Sarilumab in Patients with Rheumatoid Arthritis
D. van der Heijde, J. van Adelsberg, J. Fay, H. V. van Hoogstraten +5 more
20165 citations
Semantic Scholar
Protein targeting: the molecular basis of vectorial transport in the kidney.
J. van Adelsberg
1998Seminars in Nephrology5 citations
Semantic Scholar
SAT0058 Consistency of Radiographic Responses with Sarilumab plus Methotrexate across Subpopulations of Patients with Rheumatoid Arthritis in A Phase 3 Study
D. van der Heijde, C. Fan, H. V. van Hoogstraten, E. Mangan +3 more
20163 citations
Semantic Scholar
Flexible dosing of montelukast for treatment of seasonal allergic rhinitis: Morning or evening*
J. van Adelsberg, G. Philip, J. Menten, M. Malice +1 more
20033 citations
Semantic Scholar
222. EFFICACY AND SAFETY OF SARILUMAB IN SUBGROUPS OF PATIENTS WITH RHEUMATOID ARTHRITIS FROM 2 PHASE 3 STUDIES
M. Genovese, R. Fleischmann, E. Mangan, J. van Adelsberg +3 more
20172 citations
Semantic Scholar
SAT0180 Onset of Action of Sarilumab in Patients with Rheumatoid Arthritis in 2 Phase 3 Studies
R. Fleischmann, E. Mangan, J. van Adelsberg, J. Fay +5 more
20162 citations
Semantic Scholar

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