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Josephine Brown · SciRah

Researcher profile · Semantic Scholar

Josephine Brown

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Josephine Brown — researcher profile on SciRah

h-index: 9
Works: 24
Citations: 457

Most-cited papers

Gut microbiota dysbiosis and altered tryptophan catabolism contribute to autoimmunity in lupus-susceptible mice
Seung-Chul Choi, Josephine Brown, Ming-Hao Gong, Yong Ge +7 more
2020Science Translational Medicine218 citations Open access
Semantic Scholar
Intestinal Dysbiosis and Tryptophan Metabolism in Autoimmunity
Josephine Brown, Brian Robusto, L. Morel
2020Frontiers in Immunology51 citations Open access
Semantic Scholar
Metabolic determinants of lupus pathogenesis
Xiang-Yu Teng, Josephine Brown, Seung-Chul Choi, Wei Li +1 more
2020Immunological Reviews47 citations Open access
Semantic Scholar
Microbiota-mediated skewing of tryptophan catabolism modulates CD4+ T cells in lupus-prone mice
Josephine Brown, G. Abboud, Longhuan Ma, Seung-Chul Choi +12 more
2022iScience38 citations Open access
Semantic Scholar
Lupus susceptibility gene Esrrg modulates regulatory T cells through mitochondrial metabolism
Wei Li, Ming-Hao Gong, Y. Park, Ahmed S. Elshikha +9 more
2021JCI Insight26 citations Open access
Semantic Scholar
T cells expressing the lupus susceptibility allele Pbx1d enhance autoimmunity and atherosclerosis in dyslipidemic mice.
Wei Li, Ahmed S. Elshikha, Caleb Cornaby, Xiang-Yu Teng +9 more
2020JCI Insight24 citations Open access
Semantic Scholar
Redox Homeostasis Involvement in the Pharmacological Effects of Metformin in Systemic Lupus Erythematosus
Xiang-Yu Teng, Josephine Brown, L. Morel
2021Antioxidants and Redox Signaling20 citations Open access
Semantic Scholar
Pharmacologic inhibition of glycolysis prevents the development of lupus by altering the gut microbiome in mice
Ahmed S. Elshikha, Yong Ge, Josephine Brown, N. Kanda +8 more
2023iScience18 citations Open access
Semantic Scholar
TLR7/TLR8 activation and susceptibility genes synergize to breach gut barrier in a mouse model of lupus
Longhuan Ma, Morgan Terrell, Josephine Brown, Abigail Castellanos Garcia +2 more
2023Frontiers in Immunology11 citations Open access
Semantic Scholar
Gut Expansion of a Human Lupus Pathobiont is Associated With Autoantibody Production and T Cell Dysregulation
Longhuan Ma, Yong Ge, Natalie Six, Seung-Chul Choi +5 more
2025ACR Open Rheumatology6 citations Open access
Semantic Scholar
A combination of genetic factors and dietary tryptophan shapes gut microbial dysbiosis in a lupus-prone mouse model
Longhuan Ma, Josephine Brown, N. Kanda, Morgan Terrell +3 more
2022Journal of Immunology1 citations
Semantic Scholar
The gut microbiota from lupus-prone B6. Sle1.Sle2.Sle3 (TC) induces inflammation via a mechanism other than bacterial translocation
Josephine Brown, Seung-Chul Choi, L. Morel
2019Journal of Immunology1 citations
Semantic Scholar
Dietary tryptophan and genetic susceptibility expand gut microbiota that promote systemic autoimmune activation
Longhuan Ma, Yong Ge, Josephine Brown, Seung-Chul Choi +8 more
2024bioRxiv0 citations Open access
Semantic Scholar
THE THERAPEUTIC EFFECT OF GLYCOLYSIS INHIBITION IN LUPUS-PRONE MICE IS TRANSFERABLE THROUGH THE FECAL MICROBIOME
Josephine Brown, N. Kanda, G. Abboud, Seung-Chul Choi +9 more
20230 citations
Semantic Scholar
Ruminococcus gnavusis a pathobiont expanded by genetic susceptibility and dietary tryptophan in a lupus-prone mouse model
Longhuan Ma, Josephine Brown, Seung-Chul Choi, Ahmed S. Elshikha +5 more
2023Journal of Immunology0 citations Open access
Semantic Scholar
1302 The therapeutic effect of glycolysis inhibition in lupus-prone mice is transferable through the fecal microbiome
Ahmed S. Elshikha, Yong-Fu Ge, Josephine Brown, N. Kanda +6 more
2022Microbiome0 citations Open access
Semantic Scholar
The gut microbiota transfers the therapeutic effect of inhibiting glucose metabolism in lupus-prone mice
Ahmed S. Elshikha, Josephine Brown, N. Kanda, Yong Ge +7 more
2022Journal of Immunology0 citations
Semantic Scholar
Treatment with TLR7/8 agonist compromises intestinal epithelium integrity in a lupus prone mouse model.
Morgan Terrell, Ahmed S. Elshikha, N. Kanda, Josephine Brown +2 more
2022Journal of Immunology0 citations
Semantic Scholar
Origin and Function of Tryptophan Metabolites Modulating CD4 + T Cells in Lupus-Prone Mice
Josephine Brown, G. Abboud, Seung-Chul Choi, Longhuan Ma +12 more
2021Social Science Research Network0 citations Open access
Semantic Scholar
Lupus susceptibility gene Pbx1 promotes atherosclerosis via dysfunctional T cells in a mouse model
Wei Li, Ahmed S. Elshikha, Xiang-Yu Teng, G. Abboud +5 more
2020Journal of Immunology0 citations
Semantic Scholar
TLR7/8 agonist accelerates lupus development with heart disease in lupus-prone mice
Ahmed S. Elshikha, Xiang-Yu Teng, Wei Li, Josephine Brown +5 more
2020Journal of Immunology0 citations
Semantic Scholar
Dietary tryptophan alters CD4+ T cell function in the lupus-prone B6. Sle1.Sle2.Sle3 (TC) mouse model
Josephine Brown, Seung-Chul Choi, L. Morel
2020Journal of Immunology0 citations
Semantic Scholar
EF-03 Microbiota-associated tryptophan catabolism induces autoimmune activation in a mouse model of lupus
Seung-Chul Choi, Josephine Brown, T. Garrett, L. Morel
2018Environmental Factors0 citations Open access
Semantic Scholar
Dietary Tryptophan Modulates Autoimmunity in a Mouse Model of Lupus
Josephine Brown, Seung-Chul Choi, N. Kanda, L. Morel
2018Journal of Immunology0 citations
Semantic Scholar

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