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Deepak Srivastava · SciRah

Researcher profile · Semantic Scholar

Deepak Srivastava

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Deepak Srivastava — researcher profile on SciRah

h-index: 91
Works: 273
Citations: 37K

Most-cited papers

Contribution of rare inherited and de novo variants in 2,871 congenital heart disease probands
Sheng-Chih Jin, Jason G. Homsy, S. Zaidi, Qiong-Shi Lu +41 more
2017Nature Genetics794 citations Open access
Semantic Scholar
Regulation of Cell Cycle to Stimulate Adult Cardiomyocyte Proliferation and Cardiac Regeneration
T. Mohamed, Yen-Sin Ang, E. Radzinsky, P. Zhou +5 more
2018Cell548 citations Open access
Semantic Scholar
Contractility of single cardiomyocytes differentiated from pluripotent stem cells depends on physiological shape and substrate stiffness
A. Ribeiro, Yen-Sin Ang, Ji-Dong Fu, Renee N. Rivas +4 more
2015Proceedings of the National Academy of Sciences of the United States of America460 citations Open access
Semantic Scholar
A Long Non-Coding RNA Defines an Epigenetic Checkpoint in Cardiac Hypertrophy
Zhihua Wang, Xiao-Jing Zhang, Yan-Xiao Ji, Peng Zhang +19 more
2016Nature Medicine283 citations Open access
Semantic Scholar
In Vivo Cellular Reprogramming: The Next Generation
Deepak Srivastava, N. Dewitt
2016Cell264 citations Open access
Semantic Scholar
BET bromodomain inhibition suppresses innate inflammatory and profibrotic transcriptional networks in heart failure
Qiming Duan, Sarah McMahon, Priti Anand, Hirsh Shah +11 more
2017Science Translational Medicine246 citations Open access
Semantic Scholar
Single-cell analysis of cardiogenesis reveals basis for organ level developmental defects
T. D. de Soysa, Sanjeev S Ranade, Satoshi Okawa, S. Ravichandran +6 more
2019Nature223 citations Open access
Semantic Scholar
microRNAs as Developmental Regulators.
Kathryn N. Ivey, Deepak Srivastava
2015Cold Spring Harbor Perspectives in Biology221 citations Open access
Semantic Scholar
Miniaturized iPS-Cell-Derived Cardiac Muscles for Physiologically Relevant Drug Response Analyses
Nathaniel Huebsch, Peter Loskill, Nikhil Deveshwar, C. Spencer +15 more
2016Scientific Reports219 citations Open access
Semantic Scholar
Chemical Enhancement of In Vitro and In Vivo Direct Cardiac Reprogramming
T. Mohamed, Nicole R. Stone, Emily C. Berry, E. Radzinsky +10 more
2016Circulation218 citations Open access
Semantic Scholar
A Transcriptional Switch Governs Fibroblast Activation in Heart Disease
M. Alexanian, Pawel F. Przytycki, R. Micheletti, A. Padmanabhan +21 more
2021Nature206 citations Open access
Semantic Scholar
Human Disease Modeling Reveals Integrated Transcriptional and Epigenetic Mechanisms of NOTCH1 Haploinsufficiency
C. Theodoris, Mo-Long Li, Mark P. White, Lei Liu +4 more
2015Cell199 citations Open access
Semantic Scholar
Small molecules enable cardiac reprogramming of mouse fibroblasts with a single factor, Oct4
Haixia Wang, N. Cao, C. Spencer, Bao-ming Nie +6 more
2014Cell Reports174 citations Open access
Semantic Scholar
Oligogenic inheritance of a human heart disease involving a genetic modifier
C. Gifford, Sanjeev S Ranade, Ryan Samarakoon, Hazel T. Salunga +10 more
2019Science170 citations Open access
Semantic Scholar
Genomic analyses implicate noncoding de novo variants in congenital heart disease
Felix Richter, S. Morton, Seong Won Kim, A. Kitaygorodsky +31 more
2020Nature Genetics145 citations Open access
Semantic Scholar
Expandable Cardiovascular Progenitor Cells Reprogrammed from Fibroblasts
Yu Zhang, N. Cao, Yu Huang, C. Spencer +10 more
2016Cell Stem Cell129 citations Open access
Semantic Scholar
microRNA-1 regulates sarcomere formation and suppresses smooth muscle gene expression in the mammalian heart
Amy J. Heidersbach, C. Saxby, K. Carver-Moore, Yu Huang +4 more
2013eLife120 citations Open access
Semantic Scholar
Context-Specific Transcription Factor Functions Regulate Epigenomic and Transcriptional Dynamics During Cardiac Reprogramming
Nicole R. Stone, C. Gifford, R. Thomas, Karishma J. B. Pratt +10 more
2019Cell Stem Cell114 citations Open access
Semantic Scholar
RNA Sequencing of Mouse Sinoatrial Node Reveals an Upstream Regulatory Role for Islet-1 in Cardiac Pacemaker Cells
V. Vedantham, Giselle Galang, M. Evangelista, Rahul C. Deo +1 more
2015Circulation Research107 citations Open access
Semantic Scholar
Multi-Imaging Method to Assay the Contractile Mechanical Output of Micropatterned Human iPSC-Derived Cardiac Myocytes
A. Ribeiro, Olivier Schwab, M. Mandegar, Yen-Sin Ang +3 more
2017Circulation Research105 citations Open access
Semantic Scholar
A unified test of linkage analysis and rare-variant association for analysis of pedigree sequence data
Hao Hu, J. Roach, H. Coon, S. Guthery +21 more
2014Nature Biotechnology104 citations Open access
Semantic Scholar
A BAG3 chaperone complex maintains cardiomyocyte function during proteotoxic stress.
Luke M. Judge, Juan A. Pérez-Bermejo, Annie Truong, A. Ribeiro +10 more
2017JCI Insight93 citations Open access
Semantic Scholar
Network-based screen in iPSC-derived cells reveals therapeutic candidate for heart valve disease
C. Theodoris, Ping Zhou, Lei Liu, Yu Zhang +9 more
2020Science88 citations Open access
Semantic Scholar
BRD4 orchestrates genome folding to promote neural crest differentiation
Ricardo Linares-Saldana, Wonho Kim, N. Bolar, Hao-Yue Zhang +18 more
2021Nature Genetics82 citations Open access
Semantic Scholar
The RNA-binding Protein TDP-43 Selectively Disrupts MicroRNA-1/206 Incorporation into the RNA-induced Silencing Complex
Isabelle N. King, V. Yartseva, Donaldo Salas, Abhishek Kumar +6 more
2014Journal of Biological Chemistry77 citations Open access
Semantic Scholar
Transcription Factor Protein Interactomes Reveal Genetic Determinants in Heart Disease
Bárbara González-Terán, Maureen Pittman, Franco Felix, R. Thomas +24 more
2022Cell73 citations Open access
Semantic Scholar
Effect of biophysical cues on reprogramming to cardiomyocytes.
Junren Sia, Pengzhi Yu, Deepak Srivastava, Song Li
2016Biomaterials71 citations
Semantic Scholar
Fibronectin mediates mesendodermal cell fate decisions
Paul P. Cheng, Peter Andersen, D. Hassel, Bogac L. Kaynak +4 more
2013Development66 citations Open access
Semantic Scholar
Transient Cell Cycle Induction in Cardiomyocytes to Treat Subacute Ischemic Heart Failure
Riham R. E. Abouleisa, A. Salama, Qinghui Ou, Xian-Liang Tang +22 more
2022Circulation61 citations Open access
Semantic Scholar
Smyd1 Facilitates Heart Development by Antagonizing Oxidative and ER Stress Responses
Tara L. Rasmussen, Yanlin Ma, C. Park, J. Harriss +7 more
2015PLoS ONE55 citations Open access
Semantic Scholar
The ACVR1 R206H mutation found in fibrodysplasia ossificans progressiva increases human induced pluripotent stem cell-derived endothelial cell formation and collagen production through BMP-mediated SMAD1/5/8 signaling
Emilie Barruet, Blanca M. Morales, W. Lwin, Mark P. White +6 more
2016Stem cell research & therapeutics52 citations Open access
Semantic Scholar
Association of Damaging Variants in Genes With Increased Cancer Risk Among Patients With Congenital Heart Disease
S. Morton, A. Shimamura, P. Newburger, A. Opotowsky +19 more
2020JAMA cardiology51 citations Open access
Semantic Scholar
Long telomeres protect against age-dependent cardiac disease caused by NOTCH1 haploinsufficiency
C. Theodoris, F. Mourkioti, Yu Huang, Sanjeev S Ranade +3 more
2017Journal of Clinical Investigation51 citations Open access
Semantic Scholar
NOTCH1 Regulates Matrix Gla Protein and Calcification Gene Networks in Human Valve Endothelium
Mark P. White, C. Theodoris, Lei Liu, William J. Collins +6 more
2015Journal of Molecular and Cellular Cardiology50 citations Open access
Semantic Scholar
Direct reprogramming of fibroblasts into cardiomyocytes for cardiac regenerative medicine.
Ji-Dong Fu, Deepak Srivastava
2015Circulation Journal47 citations Open access
Semantic Scholar
GATA6 mutations in hiPSCs inform mechanisms for maldevelopment of the heart, pancreas, and diaphragm
Arun Sharma, Lauren K. Wasson, Jon A. L. Willcox, S. Morton +23 more
2020eLife44 citations Open access
Semantic Scholar
De novo Damaging Variants, Clinical Phenotypes and Post-Operative Outcomes in Congenital Heart Disease
Marko T. Boskovski, Jason Homsy, Meena Nathan, L. Sleeper +29 more
2020Circulation Genomic and Precision Medicine38 citations Open access
Semantic Scholar
BRD4 Interacts with GATA4 to Govern Mitochondrial Homeostasis in Adult Cardiomyocytes
A. Padmanabhan, M. Alexanian, Ricardo Linares-Saldana, Bárbara González-Terán +15 more
2020Circulation37 citations Open access
Semantic Scholar
Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia.
Noriko Funato, Masataka Nakamura, J. Richardson, Deepak Srivastava +1 more
2015Human Molecular Genetics37 citations Open access
Semantic Scholar
EM-mosaic detects mosaic point mutations that contribute to congenital heart disease
Alexander Hsieh, S. Morton, Jon A. L. Willcox, J. Gorham +20 more
2020Genome Medicine29 citations Open access
Semantic Scholar
De Novo Mutations in Histone-Modifying Genes in Congenital Heart Disease Congenital Heart Disease Entering a New Era of Human Genetics Commentaries on Cutting Edge Science
Benoit G. Bruneau, Deepak Srivastava
201428 citations
Semantic Scholar
Systems Analysis Implicates WAVE2 Complex in the Pathogenesis of Developmental Left-Sided Obstructive Heart Defects
J. Edwards, Andrew D. Rouillard, Nicolas F. Fernandez, Zi-Chen Wang +22 more
2020JACC: Basic to Translational Science25 citations Open access
Semantic Scholar
The E3 ubiquitin ligase Nedd4/Nedd4L is directly regulated by microRNA 1
Jun-Yi Zhu, Amy J. Heidersbach, Irfan S. Kathiriya, Bayardo I. Garay +4 more
2017Development23 citations Open access
Semantic Scholar
The Transcription Factor GATA4 Regulates Cell Type-Specific Splicing through Direct Interaction with RNA in Human iPS-Derived Cardiac Progenitors
Lili Zhu, Krishna Choudhary, Bárbara González-Terán, Yen-Sin Ang +25 more
2022Circulation21 citations Open access
Semantic Scholar
Efficient CRISPR/Cas9-based Genome Engineering in Human Pluripotent Stem Cells
Cody Kime, M. Mandegar, Deepak Srivastava, S. Yamanaka +2 more
2016Current Protocols in Human Genetics21 citations Open access
Semantic Scholar
Recent Advances in Direct Cardiac Reprogramming
Deepak Srivastava, Peng Yu
2015Current Opinion in Genetics and Development20 citations Open access
Semantic Scholar
Practical Integration‐Free Episomal Methods for Generating Human Induced Pluripotent Stem Cells
Cody Kime, T. A. Rand, Kathryn N. Ivey, Deepak Srivastava +2 more
2015Current Protocols in Human Genetics20 citations
Semantic Scholar
Specification of the mouse cardiac conduction system in the absence of Endothelin signaling
Lisa L. Hua, V. Vedantham, Ralston M. Barnes, Jianxin Hu +4 more
2014Developmental Biology19 citations Open access
Semantic Scholar
A Mesp1-dependent developmental breakpoint in transcriptional and epigenomic specification of early cardiac precursors
A. Krup, Sarah Winchester, Sanjeev S Ranade, Ayushi Agrawal +8 more
2023Development17 citations Open access
Semantic Scholar
Cold Shock Domain-Containing Protein E1 is a post-transcriptional regulator of the LDL receptor
G. A. Smith, Arun Padmanabhan, Bryan H. Lau, A. Pampana +13 more
2022Science Translational Medicine17 citations Open access
Semantic Scholar

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