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Nobutoshi Morimoto · SciRah

Researcher profile · Semantic Scholar

Nobutoshi Morimoto

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Nobutoshi Morimoto — researcher profile on SciRah

h-index: 26
Works: 77
Citations: 3,301

Most-cited papers

Mutations of optineurin in amyotrophic lateral sclerosis
H. Maruyama, H. Morino, Hidefumi Ito, Y. Izumi +23 more
2010Nature1,276 citations
Semantic Scholar
Increased autophagy in transgenic mice with a G93A mutant SOD1 gene.
Nobutoshi Morimoto, M. Nagai, Y. Ohta, K. Miyazaki +7 more
2007Brain Research254 citations
Semantic Scholar
Disruption of neurovascular unit prior to motor neuron degeneration in amyotrophic lateral sclerosis
K. Miyazaki, Y. Ohta, M. Nagai, Nobutoshi Morimoto +5 more
2011Journal of Neuroscience Research192 citations
Semantic Scholar
In vivo imaging of autophagy in a mouse stroke model
Fengfeng Tian, K. Deguchi, T. Yamashita, Y. Ohta +7 more
2010Autophagy109 citations Open access
Semantic Scholar
Atorvastatin and pitavastatin improve cognitive function and reduce senile plaque and phosphorylated tau in aged APP mice.
T. Kurata, K. Miyazaki, Kozuki Miki, V. Panin +6 more
2011Brain Research99 citations
Semantic Scholar
Early and Progressive Impairment of Spinal Blood Flow—Glucose Metabolism Coupling in Motor Neuron Degeneration of ALS Model Mice
K. Miyazaki, K. Masamoto, Nobutoshi Morimoto, T. Kurata +4 more
2012Journal of Cerebral Blood Flow and Metabolism69 citations Open access
Semantic Scholar
Reduction of cerebral infarction in rats by biliverdin associated with amelioration of oxidative stress.
K. Deguchi, Takeshi Hayashi, S. Nagotani, Y. Sehara +10 more
2008Brain Research68 citations
Semantic Scholar
Dynamic changes of mitochondrial fusion and fission proteins after transient cerebral ischemia in mice
Wen-Tao Liu, Fengfeng Tian, T. Kurata, Nobutoshi Morimoto +1 more
2012Journal of Neuroscience Research65 citations
Semantic Scholar
Antiapoptotic and antiautophagic effects of glial cell line‐derived neurotrophic factor and hepatocyte growth factor after transient middle cerebral artery occlusion in rats
Jingwei Shang, K. Deguchi, T. Yamashita, Y. Ohta +9 more
2010Journal of Neuroscience Research63 citations Open access
Semantic Scholar
Mitochondrial fusion and fission proteins expression dynamically change in a murine model of amyotrophic lateral sclerosis.
Wen-Tao Liu, T. Yamashita, Fengfeng Tian, Nobutoshi Morimoto +3 more
2013Current Neurovascular Research60 citations
Semantic Scholar
PSP as distinguished from CBD, MSA-P and PD by clinical and imaging differences at an early stage.
T. Kurata, S. Kametaka, Y. Ohta, Nobutoshi Morimoto +8 more
2011Internal medicine54 citations Open access
Semantic Scholar
Impaired antioxydative Keap1/Nrf2 system and the downstream stress protein responses in the motor neuron of ALS model mice.
Takafumi Mimoto, K. Miyazaki, Nobutoshi Morimoto, T. Kurata +3 more
2012Brain Research52 citations
Semantic Scholar
In vivo optical imaging of motor neuron autophagy in a mouse model of amyotrophic lateral sclerosis
Fengfeng Tian, Nobutoshi Morimoto, Wen-Tao Liu, Y. Ohta +3 more
2011Autophagy52 citations Open access
Semantic Scholar
Telmisartan reduces progressive accumulation of cellular amyloid beta and phosphorylated tau with inflammatory responses in aged spontaneously hypertensive stroke resistant rat.
T. Kurata, Violeta Lukić, Kozuki Miki, Daisuke Wada +7 more
2014Journal of Stroke & Cerebrovascular Diseases41 citations
Semantic Scholar
Atorvastatin and pitavastatin reduce senile plaques and inflammatory responses in a mouse model of Alzheimer’s disease
T. Kurata, K. Miyazaki, Kozuki Miki, Nobutoshi Morimoto +3 more
2012Neurological Research41 citations
Semantic Scholar
Atorvastatin and pitavastatin reduce oxidative stress and improve IR/LDL-R signals in Alzheimer’s disease
T. Kurata, K. Miyazaki, Nobutoshi Morimoto, Hiromi Kawai +3 more
2013Neurological Research40 citations
Semantic Scholar
Early decrease of mitochondrial DNA repair enzymes in spinal motor neurons of presymptomatic transgenic mice carrying a mutant SOD1 gene.
T. Murakami, M. Nagai, K. Miyazaki, Nobutoshi Morimoto +5 more
2007Brain Research39 citations
Semantic Scholar
Impaired response of hypoxic sensor protein HIF-1α and its downstream proteins in the spinal motor neurons of ALS model mice.
Kota Sato, Nobutoshi Morimoto, T. Kurata, Takafumi Mimoto +3 more
2012Brain Research38 citations
Semantic Scholar
Therapeutic benefits of intrathecal protein therapy in a mouse model of amyotrophic lateral sclerosis
Y. Ohta, T. Kamiya, M. Nagai, T. Nagata +9 more
2008Journal of Neuroscience Research34 citations
Semantic Scholar
HyperCKemia related to the initial and recurrent attacks of neuromyelitis optica.
S. Deguchi, K. Deguchi, Kota Sato, Taijun Yunoki +7 more
2012Internal medicine33 citations Open access
Semantic Scholar
Intravenous thrombolysis with neuroprotective therapy by edaravone for ischemic stroke patients older than 80 years of age.
S. Kono, K. Deguchi, Nobutoshi Morimoto, T. Kurata +11 more
2013Journal of Stroke & Cerebrovascular Diseases32 citations
Semantic Scholar
PINK1, a gene product of PARK6, accumulates in α-synucleinopathy brains
T. Murakami, Y. Moriwaki, T. Kawarabayashi, M. Nagai +11 more
2007Journal of Neurology Neurosurgery & Psychiatry30 citations Open access
Semantic Scholar
Long-term Effect of Telmisartan on Alzheimer’s Amyloid Genesis in SHR-SR After tMCAO
T. Kurata, Violeta Lukić, Kozuki Miki, Daisuke Wada +10 more
2014Translational Stroke Research28 citations
Semantic Scholar
Effect of mitochondrial transcription factor a overexpression on motor neurons in amyotrophic lateral sclerosis model mice
Nobutoshi Morimoto, K. Miyazaki, T. Kurata, Y. Ikeda +4 more
2012Journal of Neuroscience Research28 citations
Semantic Scholar
Statins have therapeutic potential for the treatment of Alzheimer's disease, likely via protection of the neurovascular unit in the AD brain.
T. Kurata, Hiromi Kawai, K. Miyazaki, Kozuki Miki +4 more
2012Journal of Neurological Sciences28 citations
Semantic Scholar
Progressive neurovascular disturbances in the cerebral cortex of Alzheimer's disease-model mice: protection by atorvastatin and pitavastatin.
T. Kurata, K. Miyazaki, Kozuki Miki, Nobutoshi Morimoto +3 more
2011Neuroscience27 citations
Semantic Scholar
Enhanced accumulation of phosphorylated α‐synuclein in double transgenic mice expressing mutant β‐amyloid precursor protein and presenilin‐1
T. Kurata, T. Kawarabayashi, T. Murakami, K. Miyazaki +12 more
200726 citations
Semantic Scholar
Progressive decrease in the level of YAPdeltaCs, prosurvival isoforms of YAP, in the spinal cord of transgenic mouse carrying a mutant SOD1 gene
Nobutoshi Morimoto, M. Nagai, K. Miyazaki, T. Kurata +5 more
2009Journal of Neuroscience Research25 citations
Semantic Scholar
Induction of parkinsonism‐related proteins in the spinal motor neurons of transgenic mouse carrying a mutant SOD1 gene
Nobutoshi Morimoto, M. Nagai, K. Miyazaki, Y. Ohta +6 more
2010Journal of Neuroscience Research24 citations
Semantic Scholar
A patient with anti-aquaporin 4 antibody presenting hypersomnolence as the initial symptom and symmetrical hypothalamic lesions.
K. Deguchi, S. Kono, S. Deguchi, Nobutoshi Morimoto +7 more
2012Journal of Neurological Sciences23 citations
Semantic Scholar
Clinical Benefits of Antioxidative Supplement Twendee X for Mild Cognitive Impairment: A Multicenter, Randomized, Double-Blind, and Placebo-Controlled Prospective Interventional Study
Koh Tadokoro, R. Morihara, Y. Ohta, N. Hishikawa +23 more
2019Journal of Alzheimer's Disease22 citations
Semantic Scholar
A novel useful tool of computerized touch panel-type screening test for evaluating cognitive function of chronic ischemic stroke patients.
K. Deguchi, S. Kono, S. Deguchi, Nobutoshi Morimoto +3 more
2013Journal of Stroke & Cerebrovascular Diseases21 citations
Semantic Scholar
Leber hereditary optic neuropathy with chorea and dementia resembling Huntington disease
Nobutoshi Morimoto, I. Nagano, K. Deguchi, T. Murakami +3 more
2004Neurology21 citations
Semantic Scholar
The identified clinical features of Parkinson's disease in homo-, heterozygous and digenic variants of PINK1.
Arisa Hayashida, Yuan-Zhe Li, H. Yoshino, Kensuke Daida +50 more
2020Neurobiology of Aging20 citations Open access
Semantic Scholar
Tissue plasminogen activator thrombolytic therapy for acute ischemic stroke in 4 hospital groups in Japan.
S. Kono, K. Deguchi, Nobutoshi Morimoto, T. Kurata +12 more
2013Journal of Stroke & Cerebrovascular Diseases20 citations
Semantic Scholar
Assessment of swallowing in motor neuron disease and Asidan/SCA36 patients with new methods.
Nobutoshi Morimoto, T. Yamashita, Kota Sato, T. Kurata +4 more
2013Journal of Neurological Sciences20 citations
Semantic Scholar
Atorvastatin and pitavastatin protect cerebellar Purkinje cells in AD model mice and preserve the cytokines MCP-1 and TNF-α.
Kozuki Miki, T. Kurata, K. Miyazaki, Nobutoshi Morimoto +3 more
2011Brain Research20 citations
Semantic Scholar
Spinal anterior horn has the capacity to self‐regenerate in amyotrophic lateral sclerosis model mice
K. Miyazaki, M. Nagai, Nobutoshi Morimoto, T. Kurata +3 more
2009Journal of Neuroscience Research18 citations
Semantic Scholar
PINK1, a gene product of PARK6, accumulates in alpha-synucleinopathy brains.
T. Murakami, Y. Moriwaki, T. Kawarabayashi, M. Nagai +11 more
2007Journal of Neurology Neurosurgery & Psychiatry17 citations
Semantic Scholar
Frontal dysfunctions of ALS-PBP patients in relation to their bulbar symptoms and rCBF decline.
Nobutoshi Morimoto, T. Kurata, Kota Sato, Y. Ikeda +2 more
2012Journal of Neurological Sciences15 citations
Semantic Scholar
Dynamic changes of mitochondrial fission proteins after transient cerebral ischemia in mice.
Wen-Tao Liu, Fengfeng Tian, T. Kurata, Nobutoshi Morimoto +1 more
2012Brain Research14 citations Open access
Semantic Scholar
Enhanced accumulation of phosphorylated alpha-synuclein in double transgenic mice expressing mutant beta-amyloid precursor protein and presenilin-1.
T. Kurata, T. Kawarabayashi, T. Murakami, K. Miyazaki +12 more
2007Journal of Neuroscience Research13 citations
Semantic Scholar
Seven amyotrophic lateral sclerosis patients diagnosed only after development of respiratory failure.
Kota Sato, Nobutoshi Morimoto, K. Deguchi, Y. Ikeda +2 more
2014Journal of clinical neuroscience12 citations
Semantic Scholar
Early and selective reduction of NOP56 (Asidan) and RNA processing proteins in the motor neuron of ALS model mice
K. Miyazaki, T. Yamashita, Nobutoshi Morimoto, Kota Sato +4 more
2013Neurological Research12 citations
Semantic Scholar
Spreading brain lesions in a familial Creutzfeldt-Jakob disease with V180I mutation over 4 years
K. Deguchi, Motonori Takamiya, S. Deguchi, Nobutoshi Morimoto +3 more
2012BMC Neurology12 citations Open access
Semantic Scholar
Expression of heat shock transcription factor 1 and its downstream target protein T-cell death associated gene 51 in the spinal cord of a mouse model of amyotrophic lateral sclerosis.
Takafumi Mimoto, Nobutoshi Morimoto, K. Miyazaki, T. Kurata +3 more
2012Brain Research11 citations
Semantic Scholar
A case of seropositive autoimmune autonomic ganglionopathy with diffuse esophageal spasm.
Nobutoshi Morimoto, Sakuma Takahashi, T. Inaba, Motonori Takamiya +6 more
2017Journal of clinical neuroscience10 citations
Semantic Scholar
A patient develops transient unique cerebral and cerebellar lesions after unruptured aneurysm coiling
K. Deguchi, Yuko Kawahara, S. Deguchi, Nobutoshi Morimoto +7 more
2015BMC Neurology10 citations Open access
Semantic Scholar
Neuroprotective and Angiogenic Effects of Bone Marrow Transplantation Combined With Granulocyte Colony-Stimulating Factor in a Mouse Model of Amyotrophic Lateral Sclerosis.
Y. Ohta, M. Nagai, K. Miyazaki, N. Tanaka +7 more
2011Cell Medicine10 citations Open access
Semantic Scholar
Differentiation of PA from early PSP with different patterns of symptoms and CBF reduction
T. Kurata, Takeshi Hayashi, T. Murakami, K. Miyazaki +12 more
2008Neurological Research9 citations
Semantic Scholar

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