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T. Nishimura · SciRah

Researcher profile · Semantic Scholar

T. Nishimura

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T. Nishimura — researcher profile on SciRah

h-index: 41
Works: 167
Citations: 6,862

Most-cited papers

Local radiation therapy inhibits tumor growth through the generation of tumor-specific CTL: its potentiation by combination with Th1 cell therapy.
T. Takeshima, K. Chamoto, D. Wakita, T. Ohkuri +4 more
2010Cancer Research245 citations Open access
Semantic Scholar
Tumor‐infiltrating IL‐17‐producing γδ T cells support the progression of tumor by promoting angiogenesis
D. Wakita, Kentaro Sumida, Y. Iwakura, Hiroyoshi Nishikawa +4 more
2010European Journal of Immunology211 citations
Semantic Scholar
IL-6–dependent spontaneous proliferation is required for the induction of colitogenic IL-17–producing CD8+ T cells
M. Tajima, D. Wakita, D. Noguchi, K. Chamoto +6 more
2008Journal of Experimental Medicine180 citations Open access
Semantic Scholar
The critical role of type‐1 innate and acquired immunity in tumor immunotherapy
H. Ikeda, K. Chamoto, Takemasa Tsuji, Yoshinori Suzuki +3 more
2004Cancer Science156 citations Open access
Semantic Scholar
Anti‐IL‐6 receptor mAb eliminates myeloid‐derived suppressor cells and inhibits tumor growth by enhancing T‐cell responses
Kentaro Sumida, D. Wakita, Yoshinori Narita, K. Masuko +5 more
2012European Journal of Immunology133 citations Open access
Semantic Scholar
Generation of tumor-specific, HLA class I-restricted human Th1 and Tc1 cells by cell engineering with tumor peptide-specific T-cell receptor genes.
Takemasa Tsuji, M. Yasukawa, Junko Matsuzaki, T. Ohkuri +10 more
2005Blood112 citations Open access
Semantic Scholar
Murine NKT cells produce Th17 cytokine interleukin-22.
M. Goto, M. Murakawa, Kumiko Kadoshima-Yamaoka, Yoshitaka Tanaka +3 more
2009Cellular Immunology110 citations
Semantic Scholar
1α,25-Dihydroxyvitamin D3 and all-trans retinoic acid synergistically inhibit the differentiation and expansion of Th17 cells.
U. Ikeda, D. Wakita, T. Ohkuri, K. Chamoto +3 more
2010Immunology Letters97 citations
Semantic Scholar
Anti‐OX40 monoclonal antibody therapy in combination with radiotherapy results in therapeutic antitumor immunity to murine lung cancer
H. Yokouchi, K. Yamazaki, K. Chamoto, E. Kikuchi +5 more
2008Cancer Science92 citations Open access
Semantic Scholar
Expression of the MAGE-A4 and NY-ESO-1 cancer-testis antigens and T cell infiltration in non-small cell lung carcinoma and their prognostic significance.
N. Yoshida, H. Abe, T. Ohkuri, D. Wakita +7 more
2006International Journal of Oncology90 citations
Semantic Scholar
STAT6-mediated signaling in Th2-dependent allergic asthma: critical role for the development of eosinophilia, airway hyper-responsiveness and mucus hypersecretion, distinct from its role in Th2 differentiation.
A. Hoshino, Takemasa Tsuji, Junko Matsuzaki, Takafumi Jinushi +12 more
2004International Immunology85 citations
Semantic Scholar
IL-17/IFN-γ double producing CD8+ T (Tc17/IFN-γ) cells: a novel cytotoxic T-cell subset converted from Tc17 cells by IL-12.
M. Tajima, D. Wakita, T. Satoh, H. Kitamura +1 more
2011International Immunology82 citations Open access
Semantic Scholar
Immunomodulating effect of vitamin D3 derivatives on type-1 cellular immunity.
I. Imazeki, Junko Matsuzaki, Keiko Tsuji, T. Nishimura
2006Biomedical research82 citations Open access
Semantic Scholar
Essential role of Toll-like receptors for dendritic cell and NK1.1(+) cell-dependent activation of type 1 immunity by Lactobacillus pentosus strain S-PT84.
S. Koizumi, D. Wakita, Tomomi Sato, R. Mitamura +7 more
2008Immunology Letters79 citations
Semantic Scholar
Blocking of IL-6 signaling pathway prevents CD4+ T cell-mediated colitis in a T(h)17-independent manner.
D. Noguchi, D. Wakita, M. Tajima, S. Ashino +5 more
2007International Immunology76 citations Open access
Semantic Scholar
The Key Role of IL-6–Arginase Cascade for Inducing Dendritic Cell–Dependent CD4+ T Cell Dysfunction in Tumor-Bearing Mice
Yoshinori Narita, H. Kitamura, D. Wakita, Kentaro Sumida +4 more
2013Journal of Immunology75 citations Open access
Semantic Scholar
Potentiation of Tumor Eradication by Adoptive Immunotherapy with T-cell Receptor Gene-Transduced T-Helper Type 1 Cells
K. Chamoto, Takemasa Tsuji, H. Funamoto, A. Kosaka +9 more
2004Cancer Research74 citations Open access
Semantic Scholar
First clinical trial of cancer vaccine therapy with artificially synthesized helper/ killer‐hybrid epitope long peptide of MAGE‐A4 cancer antigen
N. Takahashi, T. Ohkuri, S. Homma, J. Ohtake +5 more
2012Cancer Science68 citations Open access
Semantic Scholar
Immunosteroid as a regulator for Th1/Th2 balance: Its possible role in autoimmune diseases
Junko Matsuzaki, Takemasa Tsuji, I. Imazeki, H. Ikeda +1 more
2005Autoimmunity66 citations
Semantic Scholar
CSF-1–Dependent Red Pulp Macrophages Regulate CD4 T Cell Responses
D. Kurotaki, S. Kon, K. Bae, Koyu Ito +12 more
2011Journal of Immunology52 citations
Semantic Scholar
An essential role of antigen-presenting cell/T-helper type 1 cell-cell interactions in draining lymph node during complete eradication of class II-negative tumor tissue by T-helper type 1 cell therapy.
K. Chamoto, D. Wakita, Yoshinori Narita, Yue Zhang +6 more
2006Cancer Research51 citations Open access
Semantic Scholar
Potential differentiation of tumor bearing mouse CD11b+Gr-1+ immature myeloid cells into both suppressor macrophages and immunostimulatory dendritic cells.
Yoshinori Narita, D. Wakita, Takayuki Ohkur, K. Chamoto +1 more
2009Biomedical research50 citations Open access
Semantic Scholar
An indispensable role of type-1 IFNs for inducing CTL-mediated complete eradication of established tumor tissue by CpG-liposome co-encapsulated with model tumor antigen.
D. Wakita, K. Chamoto, Yue Zhang, Yoshinori Narita +6 more
2006International Immunology46 citations Open access
Semantic Scholar
Combination immunotherapy with radiation and CpG‐based tumor vaccination for the eradication of radio‐ and immuno‐resistant lung carcinoma cells
K. Chamoto, T. Takeshima, D. Wakita, T. Ohkuri +6 more
2009Cancer Science45 citations Open access
Semantic Scholar
The development of IL‐17/IFN‐γ‐double producing CTLs from Tc17 cells is driven by epigenetic suppression of Socs3 gene promoter
T. Satoh, M. Tajima, D. Wakita, H. Kitamura +1 more
2012European Journal of Immunology42 citations Open access
Semantic Scholar
IFN-gamma-dependent type 1 immunity is crucial for immunosurveillance against squamous cell carcinoma in a novel mouse carcinogenesis model.
D. Wakita, K. Chamoto, T. Ohkuri, Yoshinori Narita +7 more
2009Carcinogenesis40 citations Open access
Semantic Scholar
Osteopontin is involved in migration of eosinophils in asthma
Ayumu Takahashi, M. Kurokawa, S. Konno, Kenichiro Ito +7 more
2009Clinical and Experimental Allergy39 citations
Semantic Scholar
ASB16165, a novel inhibitor for phosphodiesterase 7A (PDE7A), suppresses IL-12-induced IFN-gamma production by mouse activated T lymphocytes.
Kumiko Kadoshima-Yamaoka, M. Murakawa, M. Goto, Yoshitaka Tanaka +10 more
2009Immunology Letters39 citations
Semantic Scholar
CpG-ODN inhibits airway inflammation at effector phase through down-regulation of antigen-specific Th2-cell migration into lung.
S. Ashino, D. Wakita, Yue Zhang, K. Chamoto +2 more
2008International Immunology35 citations Open access
Semantic Scholar
IFN-gamma-induced SOCS-1 regulates STAT6-dependent eotaxin production triggered by IL-4 and TNF-alpha.
Takeshi Sato, Rumina Saito, Takafumi Jinushi, Takemasa Tsuji +5 more
2004Biochemical and Biophysical Research Communications - BBRC34 citations
Semantic Scholar
Dectin-2 Recognizes Mannosylated O-antigens of Human Opportunistic Pathogens and Augments Lipopolysaccharide Activation of Myeloid Cells
Alexandra Wittmann, D. Lamprinaki, K. Bowles, E. Katzenellenbogen +8 more
2016Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Identification of novel helper epitope peptides of Survivin cancer-associated antigen applicable to developing helper/killer-hybrid epitope long peptide cancer vaccine.
J. Ohtake, T. Ohkuri, Y. Togashi, H. Kitamura +2 more
2014Immunology Letters32 citations
Semantic Scholar
Th1 cell adjuvant therapy combined with tumor vaccination: a novel strategy for promoting CTL responses while avoiding the accumulation of Tregs.
Yue Zhang, D. Wakita, K. Chamoto, Yoshinori Narita +3 more
2006International Immunology32 citations Open access
Semantic Scholar
Phosphodiesterase 7A inhibitor ASB16165 suppresses proliferation and cytokine production of NKT cells.
M. Goto, M. Murakawa, Kumiko Kadoshima-Yamaoka, Yoshitaka Tanaka +9 more
2009Cellular Immunology31 citations
Semantic Scholar
AsialoGM1+CD8+ central memory-type T cells in unimmunized mice as novel immunomodulator of IFN-gamma-dependent type 1 immunity.
A. Kosaka, D. Wakita, Naoki Matsubara, Y. Togashi +3 more
2007International Immunology31 citations
Semantic Scholar
Memory type 2 helper T cells induce long-lasting antitumor immunity by activating natural killer cells.
M. Kitajima, Toshihiro Ito, D. Tumes, Yusuke Endo +7 more
2011Cancer Research30 citations Open access
Semantic Scholar
Anti-IL-6 receptor antibody increases blood IL-6 level via the blockade of IL-6 clearance, but not via the induction of IL-6 production.
Y. Uchiyama, H. Yoshida, N. Koike, N. Hayakawa +3 more
2008International Immunopharmacology30 citations
Semantic Scholar
1α,25‐Dihydroxyvitamin D3 downmodulates the functional differentiation of Th1 cytokine‐conditioned bone marrow‐derived dendritic cells beneficial for cytotoxic T lymphocyte generation
Junko Matsuzaki, Takemasa Tsuji, Yue Zhang, D. Wakita +4 more
2006Cancer Science30 citations Open access
Semantic Scholar
Effect of phosphodiesterase 7 inhibitor ASB16165 on development and function of cytotoxic T lymphocyte.
Kumiko Kadoshima-Yamaoka, M. Murakawa, M. Goto, Yoshitaka Tanaka +9 more
2009International Immunopharmacology29 citations
Semantic Scholar
IFN‐γ elevates airway hyper‐responsiveness via up‐regulation of neurokinin A/neurokinin‐2 receptor signaling in a severe asthma model
Minoru Kobayashi, S. Ashino, Yasuo Shiohama, D. Wakita +2 more
2012European Journal of Immunology27 citations Open access
Semantic Scholar
Potentiation of antitumor effect of NKT cell ligand, α-galactosylceramide by combination with IL-12 on lung metastasis of malignant melanoma cells1
M. Nakui, A. Ohta, M. Sekimoto, Marimo Sato +8 more
2004Clinical and Experimental Metastasis26 citations
Semantic Scholar
Neuropeptide Signaling Activates Dendritic Cell-Mediated Type 1 Immune Responses through Neurokinin-2 Receptor
H. Kitamura, Minoru Kobayashi, D. Wakita, T. Nishimura
2012Journal of Immunology25 citations Open access
Semantic Scholar
Toll-like receptor-dependent IL-12 production by dendritic cells is required for activation of natural killer cell-mediated Type-1 immunity induced by Chrysanthemum coronarium L.
Sachi Tanaka, S. Koizumi, K. Masuko, N. Makiuchi +9 more
2011International Immunopharmacology25 citations
Semantic Scholar
Potential of Selected Strains of Lactic Acid Bacteria to Induce a Th1 Immune Profile
M. P. Ongol, T. Iguchi, Michiko Tanaka, T. Sone +3 more
2008Bioscience, biotechnology and biochemistry24 citations Open access
Semantic Scholar
A T(h)17-polarized cell population that has infiltrated the lung requires cells that convert to IFN-{gamma} production in order to induce airway hyperresponsiveness.
S. Ashino, D. Wakita, Yasuo Shiohama, Y. Iwakura +4 more
2010International Immunology23 citations
Semantic Scholar
Identification of novel helper epitopes of MAGE-A4 tumour antigen: useful tool for the propagation of Th1 cells
T. Ohkuri, D. Wakita, K. Chamoto, Y. Togashi +2 more
2009British Journal of Cancer22 citations Open access
Semantic Scholar
Effects of AhR ligands on the production of immunoglobulins in purified mouse B cells.
Takayuki Yoshida, K. Katsuya, T. Oka, S. Koizumi +3 more
2012Biomedical research21 citations Open access
Semantic Scholar
Augmentation of the therapeutic efficacy of adoptive tumor immunotherapy by in vivo administration of slowly released recombinant interleukin 2
T. Nishimura, Y. Togashi, M. Goto, H. Yagi +2 more
2004Cancer Immunology and Immunotherapy20 citations Open access
Semantic Scholar
Phagocytosis of Liposome Particles by Rat Splenic Immature Monocytes Makes Them Transiently and Highly Immunosuppressive In Ex Vivo Culture Conditions
D. Takahashi, H. Azuma, H. Sakai, Keitaro Sou +7 more
2011Journal of Pharmacology and Experimental Therapeutics17 citations
Semantic Scholar
Extracts of Larix Leptolepis effectively augments the generation of tumor antigen-specific cytotoxic T lymphocytes via activation of dendritic cells in TLR-2 and TLR-4-dependent manner.
S. Koizumi, K. Masuko, D. Wakita, Sachi Tanaka +6 more
2012Cellular Immunology16 citations Open access
Semantic Scholar

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D. Wakita×31
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D. Wakita — researcher profile on SciRah
H. Kitamura×25
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H. Kitamura — researcher profile on SciRah
K. Chamoto×24
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K. Chamoto — researcher profile on SciRah
T. Ohkuri×12
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T. Ohkuri — researcher profile on SciRah

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Y. Togashi — researcher profile on SciRah

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H. Ikeda — researcher profile on SciRah

Yoshinori Narita×8

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Yoshinori Narita — researcher profile on SciRah

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S. Ashino — researcher profile on SciRah

Takemasa Tsuji×7

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Takemasa Tsuji — researcher profile on SciRah

Junko Matsuzaki×7

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Junko Matsuzaki — researcher profile on SciRah

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Y. Iwakura — researcher profile on SciRah

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Yue Zhang — researcher profile on SciRah