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H. Ihara · SciRah

Researcher profile · Semantic Scholar

H. Ihara

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H. Ihara — researcher profile on SciRah

h-index: 20
Works: 72
Citations: 1,742

Most-cited papers

Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2.
T. Kosaka, A. Miyata, H. Ihara, S. Hara +4 more
1994European Journal of Biochemistry410 citations
Semantic Scholar
The Profibrinolytic Enzyme Subtilisin NAT Purified fromBacillus subtilis Cleaves and Inactivates Plasminogen Activator Inhibitor Type 1*
T. Urano, H. Ihara, K. Umemura, Yasuhiro Suzuki +5 more
2001Journal of Biological Chemistry167 citations Open access
Semantic Scholar
Molecular cloning of human platelet thromboxane A synthase.
Chieko Yokoyama, A. Miyata, H. Ihara, Volker Ullrich +1 more
1991Biochemical and Biophysical Research Communications - BBRC107 citations
Semantic Scholar
Selective inhibition of expression of the substance P receptor mRNA in pancreatic acinar AR42J cells by glucocorticoids.
H. Ihara, S. Nakanishi
1990Journal of Biological Chemistry88 citations Open access
Semantic Scholar
Rapid, specific and active site-catalyzed effect of tissue-plasminogen activator on hippocampus-dependent learning in mice.
R. Pawlak, N. Nagai, T. Urano, D. Napiorkowska-Pawlak +4 more
2002Neuroscience79 citations
Semantic Scholar
The cleavage and inactivation of plasminogen activator inhibitor type 1 by neutrophil elastase: the evaluation of its physiologic relevance in fibrinolysis.
Kai Wu, T. Urano, H. Ihara, Y. Takada +4 more
1995Blood79 citations Open access
Semantic Scholar
Cancer cells overexpress mRNA of urokinase‐type plasminogen activator, its receptor and inhibitors in human non‐small‐cell lung cancer tissue: Analysis by Northern blotting and in situ hybridization
Sumihito Morita, A. Sato, H. Hayakawa, H. Ihara +3 more
1998International Journal of Cancer64 citations Open access
Semantic Scholar
Characterization of the human gene (TBXAS1) encoding thromboxane synthase.
A. Miyata, Chieko Yokoyama, H. Ihara, Setsuko Bandoh +3 more
1994European Journal of Biochemistry58 citations Open access
Semantic Scholar
Tissue-Type Plasminogen Activator is Involved in the Process of Neuronal Death Induced by Oxygen–Glucose Deprivation in Culture
N. Nagai, S. Yamamoto, T. Tsuboi, H. Ihara +4 more
2001Journal of Cerebral Blood Flow and Metabolism54 citations
Semantic Scholar
heparin-produced cerebral hemorrhage after cerebral ischemia in mice matrix metalloproteinase 9 induction and expression on Essential role of endogenous tissue plasminogen activator through
Yasuhiro Suzuki, K. Kondo, Kohji Sato, N. Nagai +7 more
201351 citations
Semantic Scholar
Tissue-Type Plasminogen Activator has Paradoxical Roles in Focal Cerebral Ischemic Injury by Thrombotic Middle Cerebral Artery Occlusion with Mild or Severe Photochemical Damage in Mice
N. Nagai, Bing-Qiao Zhao, Yasuhiro Suzuki, H. Ihara +2 more
2002Journal of Cerebral Blood Flow and Metabolism46 citations Open access
Semantic Scholar
Unique secretory dynamics of tissue plasminogen activator and its modulation by plasminogen activator inhibitor-1 in vascular endothelial cells.
Yuko Suzuki, H. Mogami, H. Ihara, T. Urano
2009Blood43 citations Open access
Semantic Scholar
Proteolysis of highly polysialylated NCAM by the tissue plasminogen activator-plasmin system in rats.
A. Endo, N. Nagai, T. Urano, H. Ihara +3 more
1998Neuroscience Letters41 citations
Semantic Scholar
Induction of thromboxane synthase and prostaglandin endoperoxide synthase mRNAs in human erythroleukemia cells by phorbol ester
H. Ihara, Chieko Yokoyama, A. Miyata, T. Kosaka +3 more
1992FEBS Letters34 citations Open access
Semantic Scholar
Induction of plasminogen activator inhibitor‐1 (PAI‐1) gene expression in adipocytes by thiazolidinediones
H. Ihara, T. Urano, A. Takada, D. Loskutoff
200132 citations
Semantic Scholar
Coagulation-associated enhancement of fibrinolytic activity via a neutralization of PAI-1 activity.
T. Urano, H. Ihara, Yuko Suzuki, Y. Takada +1 more
2000Seminars in Thrombosis and Hemostasis31 citations
Semantic Scholar
Migration of mouse-induced pluripotent stem cells to glioma-conditioned medium is mediated by tumor-associated specific growth factors.
S. Koizumi, Chun-Yu Gu, S. Amano, S. Yamamoto +3 more
2011Oncology Letters30 citations Open access
Semantic Scholar
The differential effect of angiotensin II and angiotensin 1-7 on norepinephrine, epinephrine, and dopamine concentrations in rat hypothalamus: the involvement of angiotensin receptors.
R. Pawlak, D. Napiórkowska-Pawlak, Y. Takada, T. Urano +3 more
2001Brain Research Bulletin30 citations
Semantic Scholar
Activated protein C attenuates coagulation‐associated over‐expression of fibrinolytic activity by suppressing the thrombin‐dependent inactivation of PAI‐1
T. Urano, F. J. Castellino, H. Ihara, Yuko Suzuki +3 more
2003Journal of Thrombosis and Haemostasis27 citations Open access
Semantic Scholar
Changes in the central and peripheral serotonergic system in rats exposed to water-immersion restrained stress and nicotine administration.
Y. Takada, T. Urano, H. Ihara, A. Takada
1995Neurosciences research24 citations
Semantic Scholar
Human Thrombin and Calcium Bound Factor Xa Significantly Shorten tPA-Induced Fibrin Clot Lysis Time via Neutralization of Plasminogen Activator Inhibitor Type 1 Activity
T. Urano, N. Nagai, M. Matsuura, H. Ihara +2 more
1998Thrombosis and Haemostasis20 citations
Semantic Scholar
The inhibition of human factor Xa by plasminogen activator inhibitor type 1 in the presence of calcium ion, and its enhancement by heparin and vitronectin.
T. Urano, H. Ihara, Y. Takada, Nobuo Nagai +1 more
1996Biochimica et Biophysica Acta20 citations
Semantic Scholar
Impact of heart-specific disruption of the circadian clock on systemic glucose metabolism in mice
Tomomi Nakao, A. Kohsaka, Tsuyoshi Otsuka, Z. Thein +8 more
2018Chronobiology International18 citations Open access
Semantic Scholar
The cleavage and inactivation of plasminogen activator inhibitor type 1 and alpha2-antiplasmin by reptilase, a thrombin-like venom enzyme.
T. Urano, H. Ihara, Y. Takada, M. Fujie +1 more
2000Blood Coagulation and Fibrinolysis16 citations
Semantic Scholar
Involvement of Platelet Activation by P2Y12 Receptor in the Development of Transplant Arteriosclerosis in Mice
K. Yashiro, Y. Matsumoto, H. Ihara, Yasuhiro Suzuki +3 more
2009Transplantation15 citations Open access
Semantic Scholar
Sexual dimorphism in endotoxin susceptibility after partial hepatectomy in rats.
K. Inaba, Shohachi Suzuki, H. Ihara, T. Sakaguchi +4 more
2005Journal of Hepatology14 citations Open access
Semantic Scholar
Differential effects of nicotine against stress-induced changes in dopaminergic system in rat striatum and hippocampus.
Robert Pawlak, Y. Takada, Hiroshi Takahashi, T. Urano +3 more
2000European Journal of Pharmacology14 citations
Semantic Scholar
Plasminogen Activator Inhibitor Type 1 Promotes Fibrosarcoma Cell Migration by Modifying Cellular Attachment to Vitronectin via αvβ5 Integrin
Tsuyoshi Takahashi, Kazuya Suzuki, H. Ihara, H. Mogami +2 more
2005Seminars in Thrombosis and Hemostasis13 citations Open access
Semantic Scholar
Changes in blood and plasma serotonergic measurements in rats--effect of nicotine and/or exposure to different stresses.
Y. Takada, H. Ihara, T. Urano, A. Takada
1995Thrombosis Research12 citations
Semantic Scholar
Bezafibrate attenuates the overexpression of plasminogen activator inhibitor-1 messenger RNA by a combination of mono-unsaturated fatty acid and insulin in hepG2 cells.
Yuko Suzuki, T. Urano, H. Ihara, Takeshi Nakajima +4 more
2001Life Science11 citations Open access
Semantic Scholar
Correlations between platelet aggregation, fibrinolysis, peripheral and central serotonergic measures in subhuman primates.
J. Małyszko, T. Urano, R. Knöfler, H. Ihara +4 more
1994Atherosclerosis11 citations
Semantic Scholar
Relationships between serum lipids, serotonin, platelet aggregation and some fibrinolytic parameters in humans.
J. Małyszko, T. Urano, R. Knöfler, H. Ihara +2 more
1994Life Science10 citations
Semantic Scholar
Molecular cloning and expression of human thromboxane synthase.
T. Tanabe, C. Yokoyama, A. Miyata, H. Ihara +6 more
1993Journal of lipid mediators10 citations
Semantic Scholar
Mu opioid receptor expressing neurons in the rostral ventromedial medulla are the source of mechanical hypersensitivity induced by repeated restraint stress.
H. Imbe, H. Ihara
2023Brain Research8 citations
Semantic Scholar
Reexamination of the extent of the activation of Lys78 plasminogen by tissue plasminogen activator in the presence of polymerized fibrin.
T. Urano, Y. Takada, H. Ihara, A. Takada
1996Haemostasis8 citations
Semantic Scholar
Nafamostat attenuated the impairment of fibrinolysis in animal sepsis model by suppressing the increase of plasminogen activator inhibitor type 1.
T. Hryszko, Keisuke Inaba, H. Ihara, Yuko Suzuki +2 more
2006Journal of Trauma6 citations
Semantic Scholar
Human genes for prostaglandin endoperoxide synthase-2, thromboxane synthase and prostacyclin synthase.
T. Tanabe, A. Miyata, T. Nanayama, Y. Tone +4 more
1995Advances in prostaglandin, thromboxane, and leukotriene research6 citations
Semantic Scholar
Relationship between cholesterol and serotonergic measures in rats subjected to different stresses
J. Małyszko, Y. Takada, T. Urano, H. Ihara +3 more
19946 citations
Semantic Scholar
Soluble thrombomodulin quenches thrombin-mediated neutralization of PAI-1 activity and inhibits fibrinolysis through a TAFI independent mechanism
T. Urano, H. Ihara, Yasuhiro Suzuki, N. Nagai +2 more
19994 citations
Semantic Scholar
Electrical stimulation of cerebellar fastigial nucleus up-regulates uncoupling protein 4 and stabilizes mitochondrial membrane potential in the cortex
S. Yamamoto, S. Koizumi, M. Thura, H. Ihara +1 more
20113 citations
Semantic Scholar
The Effects of Dietary Cinnamic Acid and p‐coumaric Acid on Glucose and Lipid Metabolism in Normal Rats Fed a High‐Sucrose Diet
K. Kishida, Ken Takeshima, Y. Ozaki, H. Ihara
20152 citations
Semantic Scholar
A Role for Adipocyte-Enriched Transcription Factor, PPAR-γ, in Up-Regulation of PAI-1 Gene Expression during Adipogenesis.
H. Ihara, D. Loskutoff, T. Urano
20042 citations
Semantic Scholar
Induction of plasminogen activator inhibitor 1 gene expression in adipocytes by thiazolidinediones.
H. Ihara, T. Urano, A. Takada, D. Loskutoff
2001The FASEB Journal2 citations
Semantic Scholar
Effects of nicotine on serotonergic systems of brain and blood of rats exposed to footshock
Y. Takada, H. Takahashi, H. Ihara, T. Urano +1 more
19972 citations
Semantic Scholar
Novel mechanism to enhance tPA-induced fibrinolysis: effect of limited proteolysis of PAI-1 by neutrophil elastase.
T. Urano, Kai Wu, H. Ihara, Y. Takada +1 more
1996Polish Journal of Pharmacology2 citations
Semantic Scholar
Effects of nicotine and electric footshock on peripheral serotonergic measures and on platelet aggregation in whole blood of rats.
R. Knöfler, Y. Takada, H. Ihara, T. Urano +1 more
1995Life Science2 citations
Semantic Scholar
Zanthoxylum piperitum activates thermogenic gene expression and beige adipogenesis in white adipose tissues of mice
H. Ihara, Ken Takeshima, A. Kadowaki, N. Gato +2 more
2020The FASEB Journal1 citations
Semantic Scholar
Live‐cell imaging study on anti‐adipogenic and apoptotic effects of a polyphenolic resveratrol during adipocyte differentiation (959.19)
H. Ihara, Mikako Ogawa, Y. Magata
20141 citations
Semantic Scholar
Dietary p‐coumaric acid modulates hepatic gene expression involved with lipid metabolism in rats (829.6)
K. Kishida, Masaya Suzuki, H. Ihara
20141 citations
Semantic Scholar
Adipocyte-derived factors, adipokines gene regulation
H. Ihara
20091 citations
Semantic Scholar

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T. Urano — researcher profile on SciRah
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A. Miyata — researcher profile on SciRah

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