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M. Jacob · SciRah

Researcher profile · Semantic Scholar

M. Jacob

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M. Jacob — researcher profile on SciRah

h-index: 43
Works: 104
Citations: 10K

Most-cited papers

Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology.
S. Kozek-langenecker, A. Afshari, P. Albaladéjo, Cesar Aldecoa Alvarez Santullano +19 more
2013European Journal of Anaesthesiology930 citations Open access
Semantic Scholar
A Rational Approach to Perioperative Fluid Management
D. Chappell, M. Jacob, K. Hofmann-Kiefer, P. Conzen +1 more
2008Anesthesiology853 citations Open access
Semantic Scholar
Management of severe perioperative bleeding: guidelines from the European Society of Anaesthesiology: First update 2016.
S. Kozek-langenecker, Aamer B. Ahmed, A. Afshari, P. Albaladéjo +21 more
2017European Journal of Anaesthesiology663 citations Open access
Semantic Scholar
Shedding of the Endothelial Glycocalyx in Patients Undergoing Major Vascular Surgery With Global and Regional Ischemia
M. Rehm, D. Bruegger, F. Christ, P. Conzen +8 more
2007Circulation650 citations Open access
Semantic Scholar
Therapeutic strategies targeting the endothelial glycocalyx: acute deficits, but great potential.
B. F. Becker, D. Chappell, D. Bruegger, T. Annecke +1 more
2010Cardiovascular Research433 citations
Semantic Scholar
Degradation of the endothelial glycocalyx in clinical settings: searching for the sheddases
Bernhard F. Becker, M. Jacob, S. Leipert, A. Salmon +1 more
2015British Journal of Clinical Pharmacology418 citations Open access
Semantic Scholar
Hypervolemia increases release of atrial natriuretic peptide and shedding of the endothelial glycocalyx
D. Chappell, D. Bruegger, Julia Potzel, M. Jacob +5 more
2014Critical Care320 citations Open access
Semantic Scholar
TNF-α induced shedding of the endothelial glycocalyx is prevented by hydrocortisone and antithrombin
D. Chappell, K. Hofmann-Kiefer, M. Jacob, M. Rehm +4 more
2008Basic Research in Cardiology298 citations
Semantic Scholar
Endothelial glycocalyx and coronary vascular permeability: the fringe benefit
B. F. Becker, D. Chappell, M. Jacob
2010Basic Research in Cardiology277 citations
Semantic Scholar
Albumin administration in the acutely ill: what is new and where next?
J. Vincent, J. Russell, M. Jacob, G. Martin +5 more
2014Critical Care262 citations Open access
Semantic Scholar
Hydrocortisone Preserves the Vascular Barrier by Protecting the Endothelial Glycocalyx
D. Chappell, M. Jacob, K. Hofmann-Kiefer, D. Bruegger +4 more
2007Anesthesiology253 citations Open access
Semantic Scholar
Atrial natriuretic peptide induces shedding of endothelial glycocalyx in coronary vascular bed of guinea pig hearts.
D. Bruegger, M. Jacob, M. Rehm, M. Loetsch +3 more
2005American Journal of Physiology. Heart and Circulatory Physiology252 citations
Semantic Scholar
The Glycocalyx of the Human Umbilical Vein Endothelial Cell: An Impressive Structure Ex Vivo but Not in Culture
D. Chappell, M. Jacob, Oliver Paul, M. Rehm +4 more
2009Circulation Research213 citations Open access
Semantic Scholar
Contrasting Effects of Colloid and Crystalloid Resuscitation Fluids on Cardiac Vascular Permeability
M. Jacob, D. Bruegger, M. Rehm, U. Welsch +2 more
2006Anesthesiology201 citations
Semantic Scholar
Antithrombin reduces shedding of the endothelial glycocalyx following ischaemia/reperfusion.
D. Chappell, M. Jacob, K. Hofmann-Kiefer, M. Rehm +3 more
2009Cardiovascular Research191 citations Open access
Semantic Scholar
Effect of Waxy Maize-derived Hydroxyethyl Starch 130/0.4 on Renal Function in Surgical Patients
Claude D. Martin, M. Jacob, E. Vicaut, B. Guidet +2 more
2013Anesthesiology175 citations Open access
Semantic Scholar
The endothelial glycocalyx affords compatibility of Starling's principle and high cardiac interstitial albumin levels.
M. Jacob, D. Bruegger, M. Rehm, M. Stoeckelhuber +3 more
2007Cardiovascular Research172 citations Open access
Semantic Scholar
GLYCOCALYX PROTECTION REDUCES LEUKOCYTE ADHESION AFTER ISCHEMIA/REPERFUSION
D. Chappell, Nina Dörfler, M. Jacob, M. Rehm +3 more
2010Shock164 citations Open access
Semantic Scholar
The impact of the glycocalyx on microcirculatory oxygen distribution in critical illness
D. Chappell, M. Westphal, M. Jacob
2009Current Opinion in Anaesthesiology162 citations
Semantic Scholar
The 'third space'--fact or fiction?
M. Jacob, D. Chappell, M. Rehm
2009Bailliere's Best Practice & Research. Clinical Anaesthesiology151 citations
Semantic Scholar
Blood volume is normal after pre‐operative overnight fasting
M. Jacob, D. Chappell, P. Conzen, U. Finsterer +1 more
2008Acta Anaesthesiologica Scandinavica151 citations
Semantic Scholar
Regulation of blood flow and volume exchange across the microcirculation
M. Jacob, D. Chappell, B. F. Becker
2016Critical Care149 citations Open access
Semantic Scholar
Clinical update: perioperative fluid management.
M. Jacob, D. Chappell, M. Rehm
2007The Lancet146 citations
Semantic Scholar
Sevoflurane Reduces Leukocyte and Platelet Adhesion after Ischemia-Reperfusion by Protecting the Endothelial Glycocalyx
D. Chappell, B. Heindl, M. Jacob, T. Annecke +4 more
2011Anesthesiology143 citations Open access
Semantic Scholar
Release of atrial natriuretic peptide precedes shedding of the endothelial glycocalyx equally in patients undergoing on- and off-pump coronary artery bypass surgery
D. Bruegger, L. Schwartz, D. Chappell, M. Jacob +5 more
2011Basic Research in Cardiology141 citations
Semantic Scholar
The intravascular volume effect of Ringer's lactate is below 20%: a prospective study in humans
M. Jacob, D. Chappell, K. Hofmann-Kiefer, T. Helfen +5 more
2012Critical Care139 citations Open access
Semantic Scholar
Sevoflurane preserves the endothelial glycocalyx against ischaemia-reperfusion injury.
T. Annecke, D. Chappell, Congcong Chen, M. Jacob +5 more
2010British Journal of Anaesthesia129 citations Open access
Semantic Scholar
Albumin Augmentation Improves Condition of Guinea Pig Hearts After 4 hr of Cold Ischemia
M. Jacob, Oliver Paul, L. Mehringer, D. Chappell +5 more
2009Transplantation122 citations Open access
Semantic Scholar
Physiological levels of A-, B- and C-type natriuretic peptide shed the endothelial glycocalyx and enhance vascular permeability
M. Jacob, Thomas Saller, D. Chappell, M. Rehm +2 more
2013Basic Research in Cardiology116 citations
Semantic Scholar
Heparinase selectively sheds heparan sulphate from the endothelial glycocalyx
D. Chappell, M. Jacob, M. Rehm, M. Stoeckelhuber +3 more
2008Biological chemistry101 citations Open access
Semantic Scholar
The Endothelial Glycocalyx Prefers Albumin for Evoking Shear Stress-Induced, Nitric Oxide-Mediated Coronary Dilatation
M. Jacob, M. Rehm, M. Loetsch, J. O. Paul +4 more
2007Journal of Vascular Research91 citations Open access
Semantic Scholar
Role of the glycocalyx in fluid management: Small things matter.
D. Chappell, M. Jacob
2014Bailliere's Best Practice & Research. Clinical Anaesthesiology89 citations
Semantic Scholar
Re-evaluating currently available data and suggestions for planning randomised controlled studies regarding the use of hydroxyethyl starch in critically ill patients - a multidisciplinary statement
P. Meybohm, H. Van Aken, A. De Gasperi, S. De Hert +15 more
2013Critical Care81 citations Open access
Semantic Scholar
The impact of hydroxyethyl starches in cardiac surgery: a meta-analysis
M. Jacob, J. Fellahi, D. Chappell, A. Kurz
2014Critical Care80 citations Open access
Semantic Scholar
Exogenous nitric oxide requires an endothelial glycocalyx to prevent postischemic coronary vascular leak in guinea pig hearts
D. Bruegger, M. Rehm, M. Jacob, D. Chappell +4 more
2008Critical Care79 citations Open access
Semantic Scholar
Protection of glycocalyx decreases platelet adhesion after ischaemia/reperfusion: An animal study
D. Chappell, F. Brettner, Nina Doerfler, M. Jacob +5 more
2014European Journal of Anaesthesiology77 citations Open access
Semantic Scholar
Technical and physiological background of plasma volume measurement with indocyanine green: a clarification of misunderstandings.
M. Jacob, P. Conzen, U. Finsterer, A. Krafft +2 more
2007Journal of applied physiology67 citations
Semantic Scholar
Reappraising Starling: the physiology of the microcirculation
M. Jacob, D. Chappell
2013Current Opinion in Critical Care60 citations Open access
Semantic Scholar
Hydroxyethyl starch - the importance of being earnest
D. Chappell, M. Jacob
2013Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine53 citations Open access
Semantic Scholar
Causes of metabolic acidosis in canine hemorrhagic shock: role of unmeasured ions
D. Bruegger, Gregor I. Kemming, M. Jacob, Franz G. Meisner +7 more
2007Critical Care53 citations Open access
Semantic Scholar
[Expedition glycocalyx. A newly discovered "Great Barrier Reef"].
D. Chappell, M. Jacob, Bernhard F. Becker, K. Hofmann-Kiefer +2 more
2008Der Anaesthesist50 citations
Semantic Scholar
Effect of hypertonic saline dextran on acid-base balance in patients undergoing surgery of abdominal aortic aneurysm*
D. Bruegger, A. Bauer, M. Rehm, M. Niklas +4 more
2005Critical Care Medicine42 citations
Semantic Scholar
Influence of an acetate- and a lactate-based balanced infusion solution on acid base physiology and hemodynamics: an observational pilot study
K. Hofmann-Kiefer, D. Chappell, T. Kammerer, M. Jacob +3 more
2012European Journal of Medical Research39 citations Open access
Semantic Scholar
Machine learning based prediction of perioperative blood loss in orthognathic surgery.
Raphael Stehrer, L. Hingsammer, Christoph Staudigl, Stefan Hunger +3 more
2019Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery37 citations
Semantic Scholar
[Determinants of insensible fluid loss. Perspiration, protein shift and endothelial glycocalyx].
M. Jacob, D. Chappell, K. Hofmann-Kiefer, P. Conzen +2 more
2007Der Anaesthesist35 citations
Semantic Scholar
Sevoflurane mitigates shedding of hyaluronan from the coronary endothelium, also during ischemia/reperfusion: an ex vivo animal study
Congcong Chen, D. Chappell, T. Annecke, P. Conzen +4 more
2016Hypoxia31 citations Open access
Semantic Scholar
The impact of crystalloidal and colloidal infusion preparations on coronary vascular integrity, interstitial oedema and cardiac performance in isolated hearts
Y. Zausig, D. Chappell, B. F. Becker, Daniel Potschka +5 more
2013Critical Care31 citations Open access
Semantic Scholar
Albumin—Beyond Fluid Replacement in Cardiopulmonary Bypass Surgery
E. Moret, M. Jacob, M. Ranucci, A. Schramko
2014Seminars in Cardiothoracic and Vascular Anesthesia26 citations
Semantic Scholar
Erratum to: Albumin administration in the acutely ill: what is new and where next?
J. Vincent, J. Russell, M. Jacob, G. Martin +5 more
2014Critical Care24 citations Open access
Semantic Scholar
RhEPO improves time to exhaustion by non-hematopoietic factors in humans
S. Annaheim, M. Jacob, A. Krafft, C. Breymann +2 more
2016European Journal of Applied Physiology23 citations Open access
Semantic Scholar

Frequent co-authors

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D. Chappell×34
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D. Chappell — researcher profile on SciRah
M. Rehm×31
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M. Rehm — researcher profile on SciRah
B. F. Becker×26
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P. Conzen×22
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×15

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U. Welsch — researcher profile on SciRah

D. Bruegger×13

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K. Hofmann-Kiefer×8

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M. Stoeckelhuber×5

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T. Annecke — researcher profile on SciRah

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B. Guidet — researcher profile on SciRah

S. Kozek-langenecker×3

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J. Meier — researcher profile on SciRah