Esteban A. Orellana

Most-cited papers

1. Sulforhodamine B (SRB) Assay in Cell Culture to Investigate Cell Proliferation

   Esteban A. Orellana, A. Kasinski

   2016Bio-protocol386 citations Open access

   Semantic Scholar

   Save

2. METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation

   Esteban A. Orellana, Qi Liu, E. Yankova, M. Pirouz +17 more

   2021Molecules and Cells295 citations Open access

   Semantic Scholar

   Save

3. A combinatorial microRNA therapeutics approach to suppressing non-small cell lung cancer

   A. Kasinski, Kevin Kelnar, Carlos Stahlhut, Esteban A. Orellana +6 more

   2014Oncogene209 citations Open access

   Semantic Scholar

   Save

4. tRNA dysregulation and disease

   Esteban A. Orellana, E. Siegal, R. Gregory

   2022Nature reviews genetics155 citations Open access

   Semantic Scholar

   Save

5. METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing

   Hao Chen, Lei Gu, Esteban A. Orellana, Yuanyuan Wang +8 more

   2020Cell Research135 citations Open access

   Semantic Scholar

   Save

6. MicroRNAs in Cancer: A Historical Perspective on the Path from Discovery to Therapy

   Esteban A. Orellana, A. Kasinski

   2015Cancers118 citations Open access

   Semantic Scholar

   Save

7. Structural basis of regulated m7G tRNA modification by METTL1-WDR4

   Jiazhi Li, Long-Fei Wang, Quentin Hahn, Radosław P. Nowak +10 more

   2023Nature112 citations Open access

   Semantic Scholar

   Save

8. Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias

   L. Hinze, Maren Pfirrmann, Salmaan Karim, James Degar +12 more

   2019Klinische Pädiatrie87 citations Open access

   Semantic Scholar

   Save

9. FolamiRs: Ligand-targeted, vehicle-free delivery of microRNAs for the treatment of cancer

   Esteban A. Orellana, Srinivasarao Tenneti, Loganathan Rangasamy, L. Lyle +2 more

   2017Science Translational Medicine85 citations Open access

   Semantic Scholar

   Save

10. Enhancing MicroRNA Activity through Increased Endosomal Release Mediated by Nigericin

    Esteban A. Orellana, Ahmed M. Abdelaal, Loganathan Rangasamy, Srinivasarao Tenneti +3 more

    2018bioRxiv34 citations Open access

    Semantic Scholar

    Save

11. New Mechanism for Release of Endosomal Contents: Osmotic Lysis via Nigericin-Mediated K+/H+ Exchange

    Loganathan Rangasamy, Venkatesh Chelvam, A. K. Kanduluru, M. Srinivasarao +5 more

    2018Bioconjugate chemistry26 citations Open access

    Semantic Scholar

    Save

12. Identification and validation of microRNAs that synergize with miR-34a – a basis for combinatorial microRNA therapeutics

    Esteban A. Orellana, Chennan Li, Alexa Lisevick, A. Kasinski

    2019Cell Cycle18 citations Open access

    Semantic Scholar

    Save

13. A methyltransferase-independent role for METTL1 in tRNA aminoacylation and oncogenic transformation

    Raja H. Ali, Esteban A. Orellana, Su Hyun Lee, Yun-Cheol Chae +17 more

    2025Molecules and Cells13 citations Open access

    Semantic Scholar

    Save

14. Rethinking RNA Modifications: Therapeutic Strategies for Targeting Dysregulated RNA

    Isobel E. Bowles, Esteban A. Orellana

    2025Journal of Molecular Biology8 citations Open access

    Semantic Scholar

    Save

15. No vehicle, no problem

    Esteban A. Orellana, A. Kasinski

    2017OncoTarget3 citations Open access

    Semantic Scholar

    Save

16. METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation. Orellana et. al

    Esteban A. Orellana

    20211 citations

    Semantic Scholar

    Save

17. Abstract 3500: A noncatalytic role for mettl1 in oncogenic translation in soft tissue sarcoma

    R. H. Ali, Brianna Silverman, Esteban A. Orellana, A. Kennedy +8 more

    2023Cancer Research0 citations

    Semantic Scholar

    Save

18. How Cancer Cells Hijack Protein Production to Grow Quickly

    Esteban A. Orellana, R. Gregory

    2023Frontiers for Young Minds0 citations Open access

    Semantic Scholar

    Save

19. Enhancing Mirna Therapeutic Efficacy Through Combinatorial Targeting and Vehicle Free Delivery

    Esteban A. Orellana

    20180 citations

    Semantic Scholar

    Save

20. Abstract LB-332: FolamiRs: Ligand-targeted, vehicle-free microRNA replacement therapy

    Esteban A. Orellana, Srinivasarao Tenneti, Loganathan Rangasamy, P. Low +1 more

    20170 citations

    Semantic Scholar

    Save