J. Hulot

Most-cited papers

1. Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2C19 Genotype and Clopidogrel Therapy: 2022 Update

   Craig R. Lee, Jasmine A. Luzum, K. Sangkuhl, Roseann S. Gammal +13 more

   2022Clinical pharmacology and therapy466 citations Open access

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2. Effect of anakinra versus usual care in adults in hospital with COVID-19 and mild-to-moderate pneumonia (CORIMUNO-ANA-1): a randomised controlled trial

   Pierre-Louis Gilles Arthur Xavier Olivier Matthieu Raphael Phil Tharaux Pialoux Pavot Mariette Hermine Resche-Rigo, P. Tharaux, Gilles Pialoux, Arthur Pavot +496 more

   2021The Lancet Respiratory Medicine243 citations Open access

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3. Combinatorial, additive and dose-dependent drug–microbiome associations

   S. Forslund, R. Chakaroun, M. Zimmermann-Kogadeeva, L. Markó +115 more

   2021Nature208 citations Open access

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4. COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

   Sheryl Ann Ryuzo Laurent Lara Andrew Shingo Elisabeth Dia Abdukahil Abe Abel Absil Acker Adachi Adam Adrião , S. Abdukahil, Ryuzo Abe, Laurent Abel +496 more

   2021Infection75 citations Open access

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5. Epidemiology of heart failure in young adults: a French nationwide cohort study

   E. Lecoeur, O. Domengé, A. Fayol, A. Jannot +1 more

   2022European Heart Journal65 citations Open access

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6. Animal models and animal-free innovations for cardiovascular research: current status and routes to be explored. Consensus document of the ESC working group on myocardial function and the ESC Working Group on Cellular Biology of the Heart.

   J. van der Velden, F. Asselbergs, J. Bakkers, S. Batkai +57 more

   2022Cardiovascular Research63 citations Open access

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7. Actin-microtubule cytoskeletal interplay mediated by MRTF-A/SRF signaling promotes dilated cardiomyopathy caused by LMNA mutations

   Caroline Le Dour, M. Chatzifrangkeskou, C. Macquart, M. Magiera +15 more

   2022Nature Communications59 citations Open access

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8. Cardiac performance in patients hospitalized with COVID‐19: a 6 month follow‐up study

   A. Fayol, M. Livrozet, P. Boutouyrie, H. Khettab +5 more

   2021ESC Heart Failure55 citations Open access

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9. A Retrospective Single-Center Study

   A. Karras, M. Livrozet, H. Lazareth, N. Benichou +11 more

   202147 citations

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10. Vericiguat for the treatment of heart failure: mechanism of action and pharmacological properties compared with other emerging therapeutic options

    J. Hulot, J. Trochu, E. Donal, M. Galinier +3 more

    2021Expert Opinion on Pharmacotherapy41 citations

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11. Do Anxiety and Depression Predict Persistent Physical Symptoms After a Severe COVID-19 Episode? A Prospective Study

    Hugo Bottemanne, C. Gouraud, J. Hulot, A. Blanchard +6 more

    2021Frontiers in Psychiatry40 citations Open access

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12. Sarilumab in adults hospitalised with moderate-to-severe COVID-19 pneumonia (CORIMUNO-SARI-1): An open-label randomised controlled trial

    Xavier Olivier Pierre-Louis Matthieu Raphael Philippe Ser Mariette Hermine Tharaux Resche-Rigon Porcher Rava, Xavier Mariette, O. Hermine, P. Tharaux +496 more

    2021The Lancet Rheumatology38 citations Open access

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13. A First-in-Human Study of AMG 986, a Novel Apelin Receptor Agonist, in Healthy Subjects and Heart Failure Patients

    P. Winkle, S. Goldsmith, M. Koren, S. Lepage +11 more

    2022Cardiovascular Drugs and Therapy34 citations Open access

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14. The value of open-source clinical science in pandemic response: lessons from ISARIC

    Ali Sheryl Ann Nurul Najmee Ryuzo Laurent Lara Subhash Abbas Abdukahil Abdulkadir Abe Abel Absil Acharya , A. Abbas, S. Abdukahil, Nurul Najmee Abdulkadir +496 more

    2021Lancet. Infectious Diseases (Print)34 citations Open access

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15. Visual lung damage CT score at hospital admission of COVID-19 patients and 30-day mortality

    E. Charpentier, G. Soulat, A. Fayol, A. Hernigou +9 more

    2021European Radiology33 citations Open access

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16. Novel Cardiokine GDF3 Predicts Adverse Fibrotic Remodeling After Myocardial Infarction

    N. Masurkar, M. Bouvet, D. Logeart, C. Jouve +16 more

    2022Circulation25 citations Open access

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17. Aetiological classification and prognosis in patients with heart failure with preserved ejection fraction

    A. Fayol, M. Wack, M. Livrozet, Jean-Baptiste Carves +15 more

    2021ESC Heart Failure25 citations Open access

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18. Cardiac Organoids to Model and Heal Heart Failure and Cardiomyopathies

    M. Seguret, E. Vermersch, C. Jouve, J. Hulot

    2021Biomedicines23 citations Open access

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19. TRENDS IN PREVALENCE OF MAJOR AETIOLOGIES LEADING TO HEART FAILURE IN YOUNG PATIENTS: AN INTEGRATIVE REVIEW.

    O. Domengé, A. Fayol, M. Ladouceur, K. Wahbi +4 more

    2022Trends in cardiovascular medicine21 citations Open access

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20. A versatile high-throughput assay based on 3D ring-shaped cardiac tissues generated from human induced pluripotent stem cell-derived cardiomyocytes

    M. Seguret, Patricia Davidson, Stijn Robben, C. Jouve +7 more

    2024bioRxiv16 citations Open access

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21. Circadian rhythm and circulating cell-free DNA release on healthy subjects

    G. Poulet, J. Hulot, A. Blanchard, Damien Bergerot +11 more

    2022Scientific Reports16 citations Open access

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22. Association between coronary artery calcifications and 6-month mortality in hospitalized patients with COVID-19

    É. Mousseaux, A. Fayol, N. Danchin, G. Soulat +8 more

    2021Diagnostic and Interventional Imaging16 citations Open access

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23. Differential association between inflammatory cytokines and multiorgan dysfunction in COVID-19 patients with obesity

    M. Dragon-Durey, Xiao-Yi Chen, A. Kirilovsky, N. Ben Hamouda +29 more

    2021PLoS ONE16 citations Open access

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24. LRP1 Repression by SNAIL Results in ECM Remodeling in Genetic Risk for Vascular Diseases

    Lu Liu, J. Henry, Ying-Wei Liu, C. Jouve +3 more

    2024Circulation Research15 citations Open access

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25. Oropharyngeal and intestinal concentrations of opportunistic pathogens are independently associated with death of SARS-CoV-2 critically ill adults

    Juliette Patrier, Khanh Villageois-Tran, Piotr Szychowiak, S. Ruckly +85 more

    2022Critical Care15 citations Open access

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26. Proteinuria and Clinical Outcomes in Hospitalized COVID-19 Patients: A Retrospective Single-Center Study.

    A. Karras, M. Livrozet, H. Lazareth, N. Benichou +11 more

    2021American Society of Nephrology. Clinical Journal15 citations Open access

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27. Generation of iPSC line from MYH7 R403L mutation carrier with severe hypertrophic cardiomyopathy and isogenic CRISPR/Cas9 corrected control.

    V. Fontaine, L. Duboscq-Bidot, C. Jouve, M. Hamlin +7 more

    2021Stem Cell Research14 citations Open access

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28. Neutrophil Activation and Immune Thrombosis Profiles Persist in Convalescent COVID-19

    H. Hocini, A. Wiedemann, F. Blengio, C. Lefebvre +84 more

    2023Journal of Clinical Immunology12 citations Open access

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29. Genomic, Transcriptomic, and Proteomic Depiction of Induced Pluripotent Stem Cells–Derived Smooth Muscle Cells As Emerging Cellular Models for Arterial Diseases

    Lu Liu, C. Jouve, J. Henry, T. Berrandou +3 more

    2023HYPERTENSION11 citations Open access

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30. Preschool-age children maintain a distinct memory CD4+ T cell and memory B cell response after SARS-CoV-2 infection

    B. Manfroi, C. Bui, A. Sokal, Alexis Vandenberghe +50 more

    2024Science Translational Medicine9 citations

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31. Association of Impaired Left Ventricular Mitral Filling from 4D Flow Cardiac MRI and Prognosis of Hypertrophic Cardiomyopathy.

    H. Sakhi, G. Soulat, D. Craiem, U. Gencer +6 more

    2024Radiology: Cardiothoracic Imaging8 citations Open access

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32. CAVIN1-Mediated hERG Dynamics: A Novel Mechanism Underlying the Interindividual Variability in Drug-Induced Long QT

    Z. Al Sayed, C. Pereira, R. Le Borgne, Christine Viaris de Lesegno +9 more

    2024Circulation8 citations Open access

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33. [Integrins in cardiac fibrosis].

    C. Delacroix, J. Hulot

    2022Medecine sciences : M/S8 citations Open access

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34. Immune Signature Linked to COVID-19 Severity: A SARS-Score for Personalized Medicine

    Jules Russick, P. Foy, Nathalie Josseaume, M. Meylan +14 more

    2021Frontiers in Immunology6 citations Open access

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35. Hypoxia promotes a perinatal-like progenitor state in the adult murine epicardium

    Angeliqua Sayed, S. Turóczi, F. Soares-da-Silva, G. Marazzi +3 more

    2021Scientific Reports6 citations Open access

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36. Clinical pharmacology: Current innovations and future challenges

    J. Cracowski, J. Hulot, S. Laporte, M. Charvériat +3 more

    2021Fundamental & Clinical Pharmacology6 citations

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37. A gut microbiome-kidney-heart axis predictive of future cardiovascular diseases

    K. Chechi, R. Chakaroun, A. Myridakis, S. K. Forslund-Startceva +132 more

    2026Nature Communications5 citations Open access

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38. An update on oral antiplatelet drug interactions with proton pump inhibitors: what are the risks?

    G. Jourdi, J. Hulot, Pascale Gaussem

    2024Expert Opinion on Drug Metabolism & Toxicology5 citations

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39. Long-term neurological symptoms after acute COVID-19 illness requiring hospitalization in adult patients: insights from the ISARIC-COVID-19 follow-up study

    D. Battaglini, Nicole M. White, Lavienraj Premraj, Barbara Wanjiru Citarella +496 more

    2023Journal of Neurology5 citations Open access

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40. Differences in HADS and SF-36 scores 1 year after critical illness in COVID-19 patients

    Roberta T Tallarico, Benjamin Deniau, N. Fong, J. Ghosn +123 more

    2022Intensive Care Medicine5 citations Open access

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41. Modulation of Calcium Signaling on Demand to Decipher the Molecular Mechanisms of Primary Aldosteronism

    B. Fedlaoui, T. Cosentino, Z. Al Sayed, Rita Alexandre Coelho +12 more

    2025HYPERTENSION4 citations Open access

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42. Cardiometabolic Disorders and the Risk of Critical COVID-19 as Compared to Influenza Pneumonia

    A. Fayol, M. Livrozet, H. Pereira, J. Diehl +17 more

    2021Journal of Clinical Medicine4 citations Open access

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43. Meta-Analysis of Sample-Level dbGaP Data Reveals Novel Shared Genetic Link between Body Height and Crohn’s Disease

    A. Di Narzo, Itziar Frades, H. Crane, P. Crane +7 more

    2021Human Genetics4 citations Open access

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44. Rationale and design of the PACIFIC-PRESERVED (PhenomApping, ClassIFication and Innovation for Cardiac dysfunction in patients with heart failure and PRESERVED left ventricular ejection fraction) study.

    J. Hulot, P. Janiak, Philippe Boutinaud, P. Boutouyrie +15 more

    2024Archives of Cardiovascular Diseases3 citations Open access

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45. hsa-miR-548v controls the viscoelastic properties of human cardiomyocytes and improves their relaxation rates

    E. Vermersch, Salomé Neuvendel, C. Jouve, A. Ruiz-Velasco +7 more

    2024JCI Insight3 citations Open access

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46. The PACIFIC ontology for heterogeneous data management in cardiology

    Amel Raboudi, P. Hervé, Marianne Allanic, Philippe Boutinaud +8 more

    2023Journal of Biomedical Informatics3 citations Open access

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47. Suppression of tumorigenicity‐2 (ST2) is a promising biomarker in heart transplantation

    A. Galeone, J. Salem, G. Lebreton, G. Coutance +6 more

    2022Clinical Transplantation3 citations

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48. Chronic use of renin‐angiotensin‐aldosterone system blockers and mortality in COVID‐19: A multicenter prospective cohort and literature review

    N. Gault, M. Esposito-farese, M. Revest, J. Inamo +18 more

    2021Fundamental & Clinical Pharmacology3 citations Open access

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49. Mavacamten improves energy balance in a pre-clinical model of RASopathy-associated hypertrophic cardiomyopathy

    A. Ruiz-Velasco, C. Jouve, L. Deshayes, M. Kohlhaas +2 more

    2025bioRxiv2 citations Open access

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50. Inhibition of integrin alpha V reduces inflammation and the transition to heart failure after pressure overload.

    Clément Delacroix, Alexandra Achab-Ali, P. Alayrac, Marine Gandon-Renard +9 more

    2025Biochemical Pharmacology2 citations Open access

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