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D. Brunetti · SciRah

Researcher profile · Semantic Scholar

D. Brunetti

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D. Brunetti — researcher profile on SciRah

h-index: 22
Works: 43
Citations: 1,453

Most-cited papers

Loss of function of the mitochondrial peptidase PITRM1 induces proteotoxic stress and Alzheimer’s disease-like pathology in human cerebral organoids
M. Pérez, D. Ivanyuk, Vasiliki Panagiotakopoulou, G. Di Napoli +9 more
2020bioRxiv134 citations Open access
Semantic Scholar
Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome
Gizem Inak, A. Rybak-Wolf, P. Lisowski, T. Pentimalli +29 more
2021Nature Communications113 citations Open access
Semantic Scholar
Pantothenate kinase-associated neurodegeneration: altered mitochondria membrane potential and defective respiration in Pank2 knock-out mouse model
D. Brunetti, S. Dusi, M. Morbin, A. Uggetti +8 more
2012Human Molecular Genetics105 citations Open access
Semantic Scholar
Pantethine treatment is effective in recovering the disease phenotype induced by ketogenic diet in a pantothenate kinase-associated neurodegeneration mouse model
D. Brunetti, S. Dusi, C. Giordano, C. Lamperti +8 more
2013Brain : a journal of neurology100 citations Open access
Semantic Scholar
Comparative aspects of somatic cell nuclear transfer with conventional and zona-free method in cattle, horse, pig and sheep.
I. Lagutina, G. Lazzari, R. Duchi, P. Turini +5 more
2007Theriogenology89 citations
Semantic Scholar
Therapeutic Approaches to Treat Mitochondrial Diseases: “One-Size-Fits-All” and “Precision Medicine” Strategies
E. Bottani, C. Lamperti, A. Prigione, V. Tiranti +2 more
2020Pharmaceutics75 citations Open access
Semantic Scholar
Exploring the Relevance of Senotherapeutics for the Current SARS-CoV-2 Emergency and Similar Future Global Health Threats
M. Malavolta, R. Giacconi, D. Brunetti, M. Provinciali +1 more
2020Cells69 citations Open access
Semantic Scholar
Defective PITRM1 mitochondrial peptidase is associated with Aβ amyloidotic neurodegeneration
D. Brunetti, Janniche Torsvik, C. Dallabona, P. Teixeira +17 more
2015EMBO Molecular Medicine69 citations Open access
Semantic Scholar
Short-term and long-term effects of embryo culture in the surrogate sheep oviduct versus in vitro culture for different domestic species.
G. Lazzari, S. Colleoni, I. Lagutina, G. Crotti +5 more
2010Theriogenology66 citations Open access
Semantic Scholar
Transgene Expression of Green Fluorescent Protein and Germ Line Transmission in Cloned Pigs Derived from In Vitro Transfected Adult Fibroblasts
D. Brunetti, A. Perota, I. Lagutina, S. Colleoni +7 more
2008Cloning and Stem Cells61 citations
Semantic Scholar
Mitochondria in neurogenesis: Implications for mitochondrial diseases
D. Brunetti, Werner Dykstra, Stéphanie Le, A. Zink +1 more
2021Stem Cells59 citations Open access
Semantic Scholar
Direct Derivation of Neural Rosettes from Cloned Bovine Blastocysts: A Model of Early Neurulation Events and Neural Crest Specification In Vitro
G. Lazzari, S. Colleoni, S. Giannelli, D. Brunetti +4 more
2006Stem Cells58 citations
Semantic Scholar
complete neural stem cell (nsc) neuronal differentiation requires a branched chain amino acids-induced persistent metabolic shift towards energy metabolism.
F. Bifari, S. Dolci, E. Bottani, A. Pino +17 more
2020Pharmacological Research54 citations Open access
Semantic Scholar
C19orf12 and FA2H mutations are rare in Italian patients with neurodegeneration with brain iron accumulation.
C. Panteghini, G. Zorzi, P. Venco, S. Dusi +10 more
2012Seminars in Pediatric Neurology47 citations
Semantic Scholar
Targeting Multiple Mitochondrial Processes by a Metabolic Modulator Prevents Sarcopenia and Cognitive Decline in SAMP8 Mice
D. Brunetti, E. Bottani, A. Segala, S. Marchet +8 more
2020Frontiers in Pharmacology42 citations Open access
Semantic Scholar
Gene Therapy for Mitochondrial Diseases: Current Status and Future Perspective
A. Di Donfrancesco, Giulia Massaro, I. Di Meo, V. Tiranti +2 more
2022Pharmaceutics40 citations Open access
Semantic Scholar
Development, embryonic genome activity and mitochondrial characteristics of bovine-pig inter-family nuclear transfer embryos.
I. Lagutina, H. Fulka, T. Brevini, S. Antonini +6 more
2010Reproduction37 citations Open access
Semantic Scholar
A Special Amino-Acid Formula Tailored to Boosting Cell Respiration Prevents Mitochondrial Dysfunction and Oxidative Stress Caused by Doxorubicin in Mouse Cardiomyocytes
Laura Tedesco, F. Rossi, M. Ragni, C. Ruocco +5 more
2020Nutrients36 citations Open access
Semantic Scholar
SURF1 knockout cloned pigs: Early onset of a severe lethal phenotype
C. Quadalti, D. Brunetti, I. Lagutina, R. Duchi +16 more
2018Biochimica et Biophysica Acta - Molecular Basis of Disease33 citations Open access
Semantic Scholar
Role of PITRM1 in Mitochondrial Dysfunction and Neurodegeneration
D. Brunetti, Alessia Catania, C. Viscomi, M. Deleidi +3 more
2021Biomedicines32 citations Open access
Semantic Scholar
Mitochondrial PITRM1 peptidase loss-of-function in childhood cerebellar atrophy
Yeshaya Langer, A. Aran, S. Gulsuner, B. Abu-Libdeh +17 more
2018Journal of Medical Genetics32 citations Open access
Semantic Scholar
Genetic engineering including superseding microinjection: new ways to make GM pigs
C. Galli, A. Perota, D. Brunetti, I. Lagutina +2 more
2010Xenotransplantation32 citations
Semantic Scholar
Differentiation potential and GFP labeling of sheep bone marrow‐derived mesenchymal stem cells
M. Czernik, A. Fidanza, Martina Sardi, C. Galli +6 more
2013Journal of Cellular Biochemistry17 citations Open access
Semantic Scholar
Defective PITRM 1 mitochondrial peptidase is associated with A amyloidotic neurodegeneration
D. Brunetti, Janniche Torsvik, C. Dallabona, P. Teixeira +17 more
201513 citations
Semantic Scholar
Comprehensive longitudinal non-invasive quantification of healthspan and frailty in a large cohort (n = 546) of geriatric C57BL/6 J mice
Serena Marcozzi, Giorgia Bigossi, M. Giuliani, R. Giacconi +14 more
2023GeroScience12 citations Open access
Semantic Scholar
PPAR-gamma agonist pioglitazone recovers mitochondrial quality control in fibroblasts from PITRM1-deficient patients
A. Di Donfrancesco, Christian Berlingieri, M. Giacomello, Chiara Frascarelli +11 more
2023Frontiers in Pharmacology8 citations Open access
Semantic Scholar
Advances in Mitochondria-Targeted Drug Delivery
E. Bottani, D. Brunetti
2023Pharmaceutics7 citations Open access
Semantic Scholar
Editorial: Mitochondrial therapy in neurodegeneration
Anuradha Kalani, P. Chaturvedi, D. Brunetti, Komal Kalani
2023Frontiers in Pharmacology6 citations Open access
Semantic Scholar
52 Preliminary data on pig-bovine interspecies nuclear transfer embryo development.
I. Lagutina, D. Brunetti, G. Lazzari, C. Galli
20064 citations
Semantic Scholar
Inverse relationship between scores on the quality of life questionnaire SF-12 and on the Aging Males' Symptoms scale in Italian men
G. Valenti, M. Capone, G. Forti, M. Grasso +61 more
2008The Aging Male3 citations Open access
Semantic Scholar
Double transgenic Gal(-/-) piglets over-expressing hCD39
D. Brunetti, A. Perota, I. Lagutina, M. Chatelais +8 more
20091 citations
Semantic Scholar
Identification and characterization of new mitochondrial disease genes
M. Zeviani, A. Reyes, C. Viscomi, G. Civiletto +4 more
20150 citations
Semantic Scholar
Are Rare in Italian Patients With Neurodegeneration With Brain Iron Accumulation
C. Panteghini, G. Zorzi, P. Venco, S. Dusi +10 more
20120 citations
Semantic Scholar
Creation of a ubiquitous vector for expression oh hSOD1G93Ain pig
M. Chieppa, A. Perota, D. Brunetti, C. Porcario +7 more
20100 citations
Semantic Scholar
Establishment of transgenic PK15 cell clones for human thrombomodulin gene
F. Lucchini, A. Perota, D. Brunetti, I. Lagutina +2 more
20100 citations
Semantic Scholar
Production and characterization of Gal-/- minipigs over-expressing hCD55
D. Brunetti, A. Perota, I. Lagutina, M. Chatelais +5 more
20100 citations
Semantic Scholar
bovine-pig inter-family nuclear transfer embryos. 2 3
I. Lagutina, H. Fulka, S. Antonini, D. Brunetti +5 more
20100 citations
Semantic Scholar
431 GENERATION OF CLONED CD55-CD39 TRANSGENIC α1,3-GALACTOSYLTRANSFERASE DEPLETED (GAL–/–) PIGLETS
A. Perota, D. Brunetti, B. Charreau, M. Chatelais +7 more
20100 citations
Semantic Scholar
Analysis of transgene expression in transfected somatic pig cell to be used as donor in nuclear transfer
A. Perota, D. Brunetti, B. Charreau, M. Chatelais +4 more
20090 citations
Semantic Scholar
Isolation and characterization of porcine Gal KO fibroblasts expressing hCD55-hCD39 and hEPCR-hTPA
D. Brunetti, A. Perota, I. Lagutina, S. Colleoni +5 more
20080 citations
Semantic Scholar
308 Influence ofa matrix attachment region on the expression of bicistronic vectors transfected in mammalian cells cultured in vitro
A. Perota, D. Brunetti, M. Lizier, F. Lucchini +1 more
20080 citations
Semantic Scholar
300 Hemizygous prion protein gene (prnp) knockout in cattle fibroblasts
D. Brunetti, G. Rossi, I. Lagutina, R. Duchi +8 more
20080 citations
Semantic Scholar
Cardiac delivery of eGFP transfected ovine fibroblasts using percutaneous recirculation in a large animal model
Melissa J. Byrne, Anka Smolic, A. Preveolos, C. Galli +4 more
20070 citations
Semantic Scholar

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