Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

A. Hobson · SciRah

Researcher profile · Semantic Scholar

A. Hobson

Share profile

A. Hobson — researcher profile on SciRah

h-index: 16
Works: 51
Citations: 710

Most-cited papers

The structure of cobalt oxide, Co3O4
W. Smith, A. Hobson
1973117 citations
Semantic Scholar
Tricyclic Covalent Inhibitors Selectively Target Jak3 through an Active Site Thiol*
E. Goedken, M. Argiriadi, D. Banach, Bryan A. Fiamengo +12 more
2014Journal of Biological Chemistry79 citations Open access
Semantic Scholar
Stereoselective construction of quaternary centers at ambient temperature by the highly stereocontrolled migration of groups containing sp-, sp2-, and sp3-hybridized carbon atoms
C. M. Marson, A. J. Walker, J. Pickering, A. Hobson +2 more
199355 citations
Semantic Scholar
Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P5) Agonist for the Potential Treatment of Neurodegenerative Disorders.
A. Hobson, C. Harris, E. L. van der Kam, S. Turner +15 more
2015Journal of Medicinal Chemistry44 citations Open access
Semantic Scholar
Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design.
Justin D. Dietrich, K. Longenecker, Noel S. Wilson, C. Goess +25 more
2020Journal of Medicinal Chemistry35 citations Open access
Semantic Scholar
Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design.
A. Hobson, R. Judge, A. Aguirre, B. Brown +33 more
2018Journal of Medicinal Chemistry33 citations
Semantic Scholar
Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate.
A. Hobson, M. McPherson, Martin E. Hayes, C. Goess +29 more
2022Journal of Medicinal Chemistry30 citations
Semantic Scholar
An anti–TNF–glucocorticoid receptor modulator antibody-drug conjugate is efficacious against immune-mediated inflammatory diseases
Michael McPherson, A. Hobson, Axel Hernandez, C. C. Marvin +32 more
2024Science Translational Medicine29 citations
Semantic Scholar
Highly diastereoselective 1,3-dipolar cycloaddition reactions of trans-2-methylene-1,3-dithiolane 1,3-dioxide with 3-oxidopyridinium and 3-oxidopyrylium betaines: a route to the tropane skeleton.
V. Aggarwal, R. Grainger, G. Newton, P. Spargo +2 more
2003Organic and biomolecular chemistry29 citations
Semantic Scholar
Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody-Drug Conjugate Payloads.
A. Hobson, M. McPherson, W. Waegell, C. Goess +19 more
2022Journal of Medicinal Chemistry27 citations
Semantic Scholar
Covalent binders in drug discovery.
A. Vasudevan, M. Argiriadi, Aleksandra Baranczak, M. Friedman +5 more
2019Progress in Medicinal Chemistry27 citations
Semantic Scholar
Pushing the Envelope: Advancement of ADCs Outside of Oncology.
M. McPherson, A. Hobson
2019Methods in molecular biology24 citations
Semantic Scholar
Discovery of ABBV-154, an anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody-Drug Conjugate (iADC).
A. Hobson, Jianwen Xu, Dennie S. Welch, C. C. Marvin +23 more
2023Journal of Medicinal Chemistry23 citations
Semantic Scholar
Fluorogenic Platform for Real-Time Imaging of Subcellular Payload Release in Antibody–Drug Conjugates
Ferran Nadal-Bufí, Paulin L Salomon, F. de Moliner, K. Sarris +11 more
2025Journal of the American Chemical Society21 citations Open access
Semantic Scholar
Optimization of Drug-Linker to Enable Long-term Storage of Antibody-Drug Conjugate for Subcutaneous Dosing.
A. Hobson, Jianwen Xu, C. C. Marvin, M. McPherson +14 more
2023Journal of Medicinal Chemistry20 citations
Semantic Scholar
STEREOCONTROLLED SYNTHESES OF HYDROXYLATED TRICYCLIC SYSTEMS BY A NEW ANNULATION OF 2-CYCLOHEXEN-1-ONE
C. M. Marson, D. W. Benzies, A. Hobson
199118 citations
Semantic Scholar
ABBV-319: a CD19-targeting glucocorticoid receptor modulator antibody-drug conjugate therapy for B-cell malignancies
C. Chang, E. Emberley, Aloma L D'Souza, Weilong Zhao +36 more
2024Blood10 citations Open access
Semantic Scholar
The medicinal chemistry evolution of antibody-drug conjugates.
A. Hobson
2024RSC Medicinal Chemistry10 citations Open access
Semantic Scholar
Self-Immolative Carbamate Linkers for CD19-Budesonide Antibody-Drug Conjugates.
C. C. Marvin, A. Hobson, Michael McPherson, Theresa A Dunstan +10 more
2023Bioconjugate chemistry10 citations Open access
Semantic Scholar
Antibody drug conjugates beyond cytotoxic payloads.
A. Hobson
2023Progress in Medicinal Chemistry9 citations
Semantic Scholar
Linker substitution influences succinimide ring hydrolysis equilibrium impacting the stability of attachment to antibody-drug conjugates.
Lu Wang, A. Hobson, Paulin L Salomon, J. Fitzgibbons +11 more
2024RSC Medicinal Chemistry7 citations
Semantic Scholar
Novel approach to optimization of a high-throughput semipreparative LC/MS system.
J. Fitzgibbons, Sopheary Op, A. Hobson, Lisa M. Schaffter
2009Journal of combinatorial chemistry7 citations
Semantic Scholar
Convergent, stereocontrolled routes to hydroxylated tricyclic systems: a new annulation of 2-cyclohexen-1-one
C. M. Marson, D. W. Benzies, A. Hobson, H. Adams +1 more
19907 citations
Semantic Scholar
Anti-TNF Thioester Glucocorticoid Antibody-Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model.
C. C. Marvin, A. Hobson, Michael McPherson, Martin E. Hayes +14 more
2024Journal of Medicinal Chemistry6 citations
Semantic Scholar
The crystal and molecular structure of 2‐bromo‐N‐salicylideneaniline
A. Burr, A. Hobson
19696 citations
Semantic Scholar
Design of Aminobenzothiazole Inhibitors of Rho Kinases 1 and 2 by Using Protein Kinase A as a Structure Surrogate
R. Judge, A. Vasudevan, V. Scott, G. Simler +12 more
2018ChemBioChem5 citations
Semantic Scholar
Impact of dipeptide on ADC physicochemical properties and efficacy identifies Ala-Ala as the optimal dipeptide.
Lu Wang, A. Hobson, J. Fitzgibbons, Axel Hernandez +5 more
2024RSC Medicinal Chemistry4 citations
Semantic Scholar
The Medicinal Chemistry of Glucocorticoid Receptor Modulators
A. Hobson
2023SpringerBriefs in Molecular Science4 citations
Semantic Scholar
Correction to "Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate".
A. Hobson, M. McPherson, Martin E. Hayes, C. Goess +29 more
2023Journal of Medicinal Chemistry3 citations
Semantic Scholar
Lewis Acid Catalyzed Cyclizations of Epoxidized Baylis–Hillman Products: A Straightforward Synthesis of Octahydrobenzo[e]azulenes
D. Konopacki, Kelley C Shortsleeves, M. Turnbull, J. Wikaira +1 more
20153 citations
Semantic Scholar
Minimising the payload solvent exposed hydrophobic surface area optimises the antibody-drug conjugate properties.
A. Hobson, Haizhong Zhu, Wei Qiu, R. Judge +1 more
2024RSC Medicinal Chemistry2 citations Open access
Semantic Scholar
Crystal structure of Protein Kinase A in complex with the PKI peptide and a pyridinylbenzamide based inhibitor
R. Judge, A. Hobson
20182 citations
Semantic Scholar
Registration of Antibody Drug Conjugates
A. Hobson, J. Packer, C. Butler, Dirk A. Bornemeier
20172 citations Open access
Semantic Scholar
Lewis Acid Catalyzed Cyclizations of Epoxidized Baylis—Hillman Products: A Straightforward Synthesis of Octahydrobenzo[e]azulenes.
D. Konopacki, Kelley C Shortsleeves, M. Turnbull, J. Wikaira +1 more
20152 citations
Semantic Scholar
Stereoselective Construction of Quaternary Centers at Ambient Temperature by the Highly Stereocontrolled Migration of Groups Containing sp‐, sp2‐, and sp3‐Hybridized Carbon Atoms.
C. M. Marson, A. J. Walker, J. Pickering, A. Hobson +2 more
19941 citations
Semantic Scholar
Correction: Minimising the payload solvent exposed hydrophobic surface area optimises the antibody–drug conjugate properties
A. Hobson, Haizhong Zhu, Wei Qiu, R. Judge +1 more
2024RSC Medicinal Chemistry0 citations Open access
Semantic Scholar
Impact of atropisomerism on a non-steroidal glucocorticoid receptor agonist.
Zhou Xu, Zhong-Yuan Wang, Xiaona Shi, Rui Ding +4 more
2024RSC Medicinal Chemistry0 citations Open access
Semantic Scholar
Impact of drug-linker on method selection for analytical characterization and purification of antibody-drug conjugates.
Ling C Santora, A. Hobson, Lu Wang, Kan Wu
2024Analytical Methods0 citations
Semantic Scholar
Abstract 6308: Preclinical development of ABBV-319: a CD19-targeting glucocorticoid receptor modulator (GRM) agonist antibody-drug conjugate (ADC) for the treatment of B-cell malignancies
C. Chang, E. Emberley, A. D'Souza, Wei Zhao +32 more
2023Cancer Research0 citations
Semantic Scholar
Correction to "Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody-Drug Conjugate Payloads".
A. Hobson, M. McPherson, W. Waegell, C. Goess +19 more
2023Journal of Medicinal Chemistry0 citations
Semantic Scholar
Peer Review #1 of "Designing of the N-ethyl-4-(pyridin-4-yl)benzamide based potent ROCK1 inhibitors using docking, molecular dynamics, and 3D-QSAR (v0.1)"
Suparna Ghosh, S. Keretsu, Seunghyeon Joo, Cho Corresp +198 more
20210 citations Open access
Semantic Scholar
Crystal structure of Rock2 with a pyridinylbenzamide based inhibitor
R. Judge, A. Hobson
20180 citations
Semantic Scholar
Corrigendum: Design of Aminobenzothiazole Inhibitors of Rho Kinases 1 and 2 by Using Protein Kinase A as a Structure Surrogate
R. Judge, A. Vasudevan, V. Scott, G. Simler +12 more
20180 citations Open access
Semantic Scholar
Design of aminobenzothiazole inhibitors of Rho Kinases 1 and 2 utilizing PKA as a structure surrogate.
R. Judge, V. Scott, G. Simler, S. Pratt +7 more
20180 citations
Semantic Scholar
Crystal structure of Protein Kinase A in complex with the PKI peptide and an amino-pyridinylbenzamide based inhibitor.
R. Judge, A. Hobson
20180 citations
Semantic Scholar
Crystal structure of Rock1 with a pyridinylbenzamide based inhibitor
R. Judge, A. Hobson
20180 citations
Semantic Scholar
Fused heterocyclic derivatives as modulators of S1P
P. Smid, W. I. Iwema Bakker, H. K. A. C. Coolen, L. Sliedregt +3 more
20110 citations
Semantic Scholar
STEREOSELECTIVE CONSTRUCTION OF QUATERNARY CENTERS AT AMBIENT-TEMPERATURE BY THE HIGHLY STEREOCONTROLLED MIGRATION OF GROUPS CONTAINING SP-HYBRIDIZED,SP(2)-HYBRIDIZED-, AND SP(3)-HYBRIDIZED CARBON-ATOMS
C. Marson, A. Walker, J. Pickering, A. Hobson +2 more
19930 citations
Semantic Scholar
Stereocontrolled Syntheses of Hydroxylated Tricyclic Systems by a New Annulation of 2-Cyclohexen-1-one.
C. M. Marson, D. W. Benzies, A. Hobson
19910 citations
Semantic Scholar
KRISTALL‐ UND MOLEKULARSTRUKTUR VON 2‐BROM‐N‐SALICYLIDEN‐ANILIN
A. Burr, A. Hobson
19700 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

Axel Hernandez×12
Invite
Axel Hernandez — researcher profile on SciRah
C. C. Marvin×12
Invite
C. C. Marvin — researcher profile on SciRah
Lu Wang×10
Invite
Lu Wang — researcher profile on SciRah
J. Fitzgibbons×10
Invite
J. Fitzgibbons — researcher profile on SciRah

×9

Invite

C. Goess — researcher profile on SciRah

Invite

S. Mathieu — researcher profile on SciRah

Zhong-Yuan Wang×8

Invite

Zhong-Yuan Wang — researcher profile on SciRah

Agnieszka K Bischoff×8

Invite

Agnieszka K Bischoff — researcher profile on SciRah

Invite

S. Bryant — researcher profile on SciRah

Ling C Santora×7

Invite

Ling C Santora — researcher profile on SciRah

Invite

Lu Wang — researcher profile on SciRah

Michael McPherson×7

Invite

Michael McPherson — researcher profile on SciRah