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N. Hashii · SciRah

Researcher profile · Semantic Scholar

N. Hashii

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N. Hashii — researcher profile on SciRah

h-index: 27
Works: 101
Citations: 1,967

Most-cited papers

β-Galactoside α2,6-Sialyltranferase 1 Promotes Transforming Growth Factor-β-mediated Epithelial-Mesenchymal Transition*
Jishun Lu, T. Isaji, Sanghun Im, Tomohiko Fukuda +4 more
2014Journal of Biological Chemistry95 citations Open access
Semantic Scholar
An Oncogenic Protein Golgi Phosphoprotein 3 Up-regulates Cell Migration via Sialylation*
T. Isaji, Sanghun Im, W. Gu, Yu-Qin Wang +8 more
2014Journal of Biological Chemistry95 citations Open access
Semantic Scholar
Isotope tag method for quantitative analysis of carbohydrates by liquid chromatography-mass spectrometry.
Jin Yuan, N. Hashii, N. Kawasaki, S. Itoh +2 more
2005Journal of Chromatography A85 citations
Semantic Scholar
The significance of glycosylation analysis in development of biopharmaceuticals.
N. Kawasaki, S. Itoh, N. Hashii, D. Takakura +3 more
2009Biological and Pharmaceutical Bulletin69 citations Open access
Semantic Scholar
A novel antibody for human induced pluripotent stem cells and embryonic stem cells recognizes a type of keratan sulfate lacking oversulfated structures.
K. Kawabe, Daiki Tateyama, H. Toyoda, Nana Kawasaki +12 more
2013Glycobiology68 citations Open access
Semantic Scholar
Effects of terminal galactose residues in mannose α1-6 arm of Fc-glycan on the effector functions of therapeutic monoclonal antibodies
Michihiko Aoyama, N. Hashii, Wataru Tsukimura, K. Osumi +5 more
2019mAbs66 citations Open access
Semantic Scholar
Assessing the Heterogeneity of the Fc-Glycan of a Therapeutic Antibody Using an engineered FcγReceptor IIIa-Immobilized Column
Masato Kiyoshi, José M. M. Caaveiro, M. Tada, H. Tamura +12 more
2018Scientific Reports66 citations Open access
Semantic Scholar
Helicobacter pylori HP0518 affects flagellin glycosylation to alter bacterial motility
Hiroshi Asakura, Y. Churin, Bianca Bauer, J. Boettcher +7 more
2010Molecular Microbiology62 citations Open access
Semantic Scholar
α1‐3/4 fucosylation at Asn 241 of β‐haptoglobin is a novel marker for colon cancer: A combinatorial approach for development of glycan biomarkers
Seung-Yeol Park, S. Lee, N. Kawasaki, S. Itoh +6 more
2012International Journal of Cancer59 citations Open access
Semantic Scholar
A comparative study of monosaccharide composition analysis as a carbohydrate test for biopharmaceuticals.
A. Harazono, Tetsu Kobayashi, N. Kawasaki, S. Itoh +21 more
2011Biologicals (Print)59 citations
Semantic Scholar
Site-specific N-glycosylation analysis of human plasma ceruloplasmin using liquid chromatography with electrospray ionization tandem mass spectrometry.
A. Harazono, N. Kawasaki, S. Itoh, N. Hashii +3 more
2006Analytical Biochemistry56 citations
Semantic Scholar
Alteration of N‐glycosylation in the kidney in a mouse model of systemic lupus erythematosus: relative quantification of N‐glycans using an isotope‐tagging method
N. Hashii, N. Kawasaki, S. Itoh, Yukari Nakajima +2 more
2009Immunology50 citations Open access
Semantic Scholar
Mass spectrometric glycoform profiling of the innovator and biosimilar erythropoietin and darbepoetin by LC/ESI-MS.
A. Harazono, N. Hashii, R. Kuribayashi, Shiori Nakazawa +1 more
2013Journal of Pharmaceutical and Biomedical Analysis49 citations
Semantic Scholar
Degradation of Stop Codon Read-through Mutant Proteins via the Ubiquitin-Proteasome System Causes Hereditary Disorders*
N. Shibata, Nobumichi Ohoka, Yusuke Sugaki, Chiaki Onodera +7 more
2015Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Designing strong inducible synthetic promoters in yeasts
Masahiro Tominaga, Y. Shima, Kenta Nozaki, Yoichiro Ito +11 more
2024Nature Communications41 citations Open access
Semantic Scholar
Structural and biochemical characterization of O-mannose-linked human natural killer-1 glycan expressed on phosphacan in developing mouse brains.
Jyoji Morise, Yasuhiko Kizuka, Keiko Yabuno, Y. Tonoyama +9 more
2014Glycobiology40 citations Open access
Semantic Scholar
Antibody feedback contributes to facilitating the development of Omicron-reactive memory B cells in SARS-CoV-2 mRNA vaccinees
Takeshi Inoue, Ryo Shinnakasu, C. Kawai, Hiromi Yamamoto +16 more
2022Journal of Experimental Medicine38 citations Open access
Semantic Scholar
Characterization of anti-CD20 monoclonal antibody produced by transgenic silkworms (Bombyx mori)
M. Tada, K. Tatematsu, A. Ishii-Watabe, A. Harazono +4 more
2015mAbs38 citations Open access
Semantic Scholar
Tetrameric interaction of the ectoenzyme CD38 on the cell surface enables its catalytic and raft-association activities.
M. Hara-Yokoyama, M. Kukimoto-Niino, Kazue Terasawa, S. Harumiya +20 more
2012Structure36 citations Open access
Semantic Scholar
Establishment of a highly precise multi-attribute method for the characterization and quality control of therapeutic monoclonal antibodies
Michiko Tajiri-Tsukada, N. Hashii, A. Ishii-Watabe
2020Bioengineered35 citations Open access
Semantic Scholar
Selective glycopeptide profiling by acetone enrichment and LC/MS.
D. Takakura, A. Harazono, N. Hashii, N. Kawasaki
2014Journal of Proteomics33 citations
Semantic Scholar
N-linked oligosaccharide analysis of rat brain Thy-1 by liquid chromatography with graphitized carbon column/ion trap-Fourier transform ion cyclotron resonance mass spectrometry in positive and negative ion modes.
S. Itoh, N. Kawasaki, N. Hashii, A. Harazono +3 more
2006Journal of Chromatography A32 citations
Semantic Scholar
Glycomic/glycoproteomic analysis by liquid chromatography/mass spectrometry: Analysis of glycan structural alteration in cells
N. Hashii, N. Kawasaki, S. Itoh, Mashashi Hyuga +2 more
2005Proteomics31 citations
Semantic Scholar
Change in N-Glycosylation of Plasma Proteins in Japanese Semisupercentenarians
Y. Miura, N. Hashii, H. Tsumoto, D. Takakura +6 more
2015PLoS ONE30 citations Open access
Semantic Scholar
Interaction of Platelet Endothelial Cell Adhesion Molecule (PECAM) with α2,6-Sialylated Glycan Regulates Its Cell Surface Residency and Anti-apoptotic Role*
S. Kitazume, R. Imamaki, A. Kurimoto, K. Ogawa +9 more
2014Journal of Biological Chemistry29 citations Open access
Semantic Scholar
Simultaneous glycosylation analysis of human serum glycoproteins by high-performance liquid chromatography/tandem mass spectrometry.
A. Harazono, N. Kawasaki, S. Itoh, N. Hashii +3 more
2008Journal of chromatography. B, Analytical technologies in the biomedical and life sciences28 citations
Semantic Scholar
A Sulfated Glycosaminoglycan Linkage Region Is a Novel Type of Human Natural Killer-1 (HNK-1) Epitope Expressed on Aggrecan in Perineuronal Nets
Keiko Yabuno, Jyoji Morise, Yasuhiko Kizuka, N. Hashii +7 more
2015PLoS ONE27 citations Open access
Semantic Scholar
Structural analysis of the carbohydrate backbone of Vibrio parahaemolyticus O2 lipopolysaccharides.
N. Hashii, Y. Isshiki, T. Iguchi, S. Kondo
2003Carbohydrate Research25 citations
Semantic Scholar
Glycan engineering of the SARS-CoV-2 receptor-binding domain elicits cross-neutralizing antibodies for SARS-related viruses
Ryo Shinnakasu, S. Sakakibara, Hiromi Yamamoto, Po-Hung Wang +15 more
2021Journal of Experimental Medicine24 citations Open access
Semantic Scholar
Functional Regulation of Sugar Assimilation by N-Glycan-specific Interaction of Pancreatic α-Amylase with Glycoproteins of Duodenal Brush Border Membrane*
Kimie Asanuma-Date, Yukihiko Hirano, Na Le, Kotone Sano +8 more
2012Journal of Biological Chemistry24 citations Open access
Semantic Scholar
Study on the quality control of cell therapy products. Determination of N-glycolylneuraminic acid incorporated into human cells by nano-flow liquid chromatography/Fourier transformation ion cyclotron mass spectrometry.
N. Hashii, N. Kawasaki, Yukari Nakajima, M. Toyoda +5 more
2007Journal of Chromatography A24 citations
Semantic Scholar
Comparison of analytical methods for profiling N- and O-linked glycans from cultured cell lines
Hiromi Ito, H. Kaji, A. Togayachi, P. Azadi +27 more
2015Glycoconjugate Journal23 citations Open access
Semantic Scholar
Rapid evaluation for heterogeneities in monoclonal antibodies by liquid chromatography/mass spectrometry with a column-switching system.
R. Kuribayashi, N. Hashii, A. Harazono, N. Kawasaki
2012Journal of Pharmaceutical and Biomedical Analysis21 citations
Semantic Scholar
Heparin identification test and purity test for OSCS in heparin sodium and heparin calcium by weak anion-exchange high-performance liquid chromatography.
N. Hashii, N. Kawasaki, S. Itoh, Yan Qin +19 more
2010Biologicals (Print)21 citations
Semantic Scholar
Characterization of a gel-separated unknown glycoprotein by liquid chromatography/multistage tandem mass spectrometry: analysis of rat brain Thy-1 separated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis.
S. Itoh, N. Kawasaki, A. Harazono, N. Hashii +3 more
2005Journal of Chromatography A21 citations
Semantic Scholar
In-depth site-specific O-Glycosylation analysis of therapeutic Fc-fusion protein by electron-transfer/higher-energy collisional dissociation mass spectrometry.
N. Hashii, Junya Suzuki, H. Hanamatsu, Jun-ichi Furukawa +1 more
2019Biologicals (Print)20 citations
Semantic Scholar
Analysis of oligomeric stability of insulin analogs using hydrogen/deuterium exchange mass spectrometry.
Shiori Nakazawa, N. Hashii, A. Harazono, N. Kawasaki
2012Analytical Biochemistry20 citations
Semantic Scholar
Survival Signals of Hepatic Stellate Cells in Liver Regeneration Are Regulated by Glycosylation Changes in Rat Vitronectin, Especially Decreased Sialylation*
Kotone Sano, Y. Miyamoto, N. Kawasaki, N. Hashii +7 more
2010Journal of Biological Chemistry19 citations Open access
Semantic Scholar
Analysis of the local dynamics of human insulin and a rapid-acting insulin analog by hydrogen/deuterium exchange mass spectrometry.
Shiori Nakazawa, J. Ahn, N. Hashii, K. Hirose +1 more
2013Biochimica et Biophysica Acta18 citations Open access
Semantic Scholar
Structural characterization of the carbohydrate backbone of the lipopolysaccharide of Vibrio parahaemolyticus O-untypeable strain KX-V212 isolated from a patient.
N. Hashii, Y. Isshiki, T. Iguchi, S. Kondo
2003Carbohydrate Research18 citations
Semantic Scholar
The influence of antibody engineering on Fc conformation and Fc receptor binding properties: Analysis of FcRn-binding engineered antibodies and an Fc fusion protein
Takuo Suzuki, N. Hashii, M. Tada, A. Ishii-Watabe
2021mAbs17 citations Open access
Semantic Scholar
Purified EDEM3 or EDEM1 alone produces determinant oligosaccharide structures from M8B in mammalian glycoprotein ERAD
Ginto George, Satoshi Ninagawa, H. Yagi, Jun-ichi Furukawa +11 more
2021eLife16 citations Open access
Semantic Scholar
Characterization of N-glycan heterogeneities of erythropoietin products by liquid chromatography/mass spectrometry and multivariate analysis.
N. Hashii, A. Harazono, R. Kuribayashi, D. Takakura +1 more
2014Rapid Communications in Mass Spectrometry16 citations
Semantic Scholar
Identification of glycoproteins carrying a target glycan-motif by liquid chromatography/multiple-stage mass spectrometry: identification of Lewis x-conjugated glycoproteins in mouse kidney.
N. Hashii, N. Kawasaki, S. Itoh, Yukari Nakajima +3 more
2009Journal of Proteome Research16 citations
Semantic Scholar
Specific detection of Lewis x-carbohydrates in biological samples using liquid chromatography/multiple-stage tandem mass spectrometry.
N. Hashii, N. Kawasaki, S. Itoh, A. Harazono +3 more
2005Rapid Communications in Mass Spectrometry16 citations
Semantic Scholar
Characteristic glycopeptides associated with extreme human longevity identified through plasma glycoproteomics.
Y. Miura, N. Hashii, Yuki Ohta, Yoko Itakura +9 more
2018Biochimica et Biophysica Acta - General Subjects15 citations
Semantic Scholar
An improved in‐gel digestion method for efficient identification of protein and glycosylation analysis of glycoproteins using guanidine hydrochloride
D. Takakura, N. Hashii, N. Kawasaki
2014Proteomics15 citations
Semantic Scholar
Structure and serological characterization of 5,7-diamino-3,5,7,9-tetradeoxy-non-2-ulosonic acid isolated from lipopolysaccharides of Vibrio parahaemolyticus O2 and O-untypable strain KX-V212.
N. Hashii, Y. Isshiki, T. Iguchi, K. Hisatsune +1 more
2003Carbohydrate Research15 citations
Semantic Scholar
Campylobacter jejuni pdxA Affects Flagellum-Mediated Motility to Alter Host Colonization
Hiroshi Asakura, N. Hashii, Masashi Uema, N. Kawasaki +3 more
2013PLoS ONE14 citations Open access
Semantic Scholar
NMR-based structural validation of therapeutic antibody produced in Nicotiana benthamiana
H. Yagi, Noriho Fukuzawa, Y. Tasaka, K. Matsuo +8 more
2015Plant Cell Reports13 citations
Semantic Scholar

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