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T. V. Seraphim · SciRah

Researcher profile · Semantic Scholar

T. V. Seraphim

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T. V. Seraphim — researcher profile on SciRah

h-index: 17
Works: 33
Citations: 905

Most-cited papers

Acyldepsipeptide Analogs Dysregulate Human Mitochondrial ClpP Protease Activity and Cause Apoptotic Cell Death.
Keith S. Wong, M. Mabanglo, T. V. Seraphim, A. Mollica +14 more
2018Cell Chemical Biology98 citations Open access
Semantic Scholar
A Draft of the Human Septin Interactome
Marcel Nakahira, J. N. Macêdo, T. V. Seraphim, N. Cavalcante +10 more
2010PLoS ONE95 citations Open access
Semantic Scholar
Exploiting supramolecular interactions to produce bevacizumab-loaded nanoparticles for potential mucosal delivery
L. M. Ferreira, J. D. Alonso, Charlene P. Kiill, N. N. Ferreira +7 more
2018European Polymer Journal88 citations Open access
Semantic Scholar
Potential Antileukemia Effect and Structural Analyses of SRPK Inhibition by N-(2-(Piperidin-1-yl)-5-(Trifluoromethyl)Phenyl)Isonicotinamide (SRPIN340)
R. Siqueira, Éverton de Almeida Alves Barbosa, M. D. Polêto, G. Righetto +15 more
2015PLoS ONE80 citations Open access
Semantic Scholar
Features of the Chaperone Cellular Network Revealed through Systematic Interaction Mapping.
Kamran Rizzolo, Jennifer Huen, Ashwani Kumar, S. Phanse +16 more
2017Cell Reports53 citations Open access
Semantic Scholar
Alginate hydrogel improves anti‐angiogenic bevacizumab activity in cancer therapy
N. N. Ferreira, L. M. Ferreira, V. Miranda-Gonçalves, R. Reis +4 more
2017European journal of pharmaceutics and biopharmaceutics46 citations Open access
Semantic Scholar
AAA+ proteins.
T. V. Seraphim, W. Houry
2020Current Biology45 citations Open access
Semantic Scholar
Structural and functional studies of Leishmania braziliensis Hsp90.
K. P. Silva, T. V. Seraphim, J. Borges
2013Biochimica et Biophysica Acta41 citations Open access
Semantic Scholar
ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores
M. Mabanglo, E. Leung, S. Vahidi, T. V. Seraphim +16 more
2019Communications Biology34 citations Open access
Semantic Scholar
Identification of Regions Involved in Substrate Binding and Dimer Stabilization within the Central Domains of Yeast Hsp40 Sis1
J. Borges, T. V. Seraphim, David Z. Mokry, F. C. Almeida +2 more
2012PLoS ONE34 citations Open access
Semantic Scholar
A review of multi-domain and flexible molecular chaperones studies by small-angle X-ray scattering
J. Borges, T. V. Seraphim, P. R. Dores-Silva, Leandro R. S. Barbosa
2016Biophysical Reviews26 citations Open access
Semantic Scholar
Sorafenib as an Inhibitor of RUVBL2
Nardin Nano, F. Ugwu, T. V. Seraphim, Tangzhi Li +7 more
2020Biomolecules24 citations Open access
Semantic Scholar
Low Resolution Structural Studies Indicate that the Activator of Hsp90 ATPase 1 (Aha1) of Leishmania braziliensis Has an Elongated Shape Which Allows Its Interaction with Both N- and M-Domains of Hsp90
T. V. Seraphim, M. Alves, I. M. Silva, Francisco E. R. Gomes +4 more
2013PLoS ONE24 citations Open access
Semantic Scholar
Identification of two p23 co‐chaperone isoforms in Leishmania braziliensis exhibiting similar structures and Hsp90 interaction properties despite divergent stabilities
F. A. H. Batista, G. S. Almeida, T. V. Seraphim, K. P. Silva +3 more
2015The FEBS Journal21 citations Open access
Semantic Scholar
The C-terminal region of the human p23 chaperone modulates its structure and function.
T. V. Seraphim, L. Gava, David Z. Mokry, Thiago C. Cagliari +3 more
2015Archives of Biochemistry and Biophysics19 citations
Semantic Scholar
The Interaction Networks of Hsp70 and Hsp90 in the Plasmodium and Leishmania Parasites
T. V. Seraphim, C. H. Ramos, J. Borges
201419 citations Open access
Semantic Scholar
Structural studies of the Hsp70/Hsp90 organizing protein of Plasmodium falciparum and its modulation of Hsp70 and Hsp90 ATPase activities.
N. S. M. Silva, D. E. Bertolino-Reis, P. R. Dores-Silva, Fátima B Anneta +3 more
2019Biochimica et Biophysica Acta - Proteins and Proteomics18 citations Open access
Semantic Scholar
Plasmodium falciparum R2TP complex: driver of parasite Hsp90 function
T. V. Seraphim, Graham Chakafana, A. Shonhai, W. Houry
2019Biophysical Reviews17 citations Open access
Semantic Scholar
Structural and functional studies of the Leishmania braziliensis SGT co-chaperone indicate that it shares structural features with HIP and can interact with both Hsp90 and Hsp70 with similar affinities.
Amanda L. S. Coto, T. V. Seraphim, F. A. H. Batista, P. R. Dores-Silva +4 more
2018International Journal of Biological Macromolecules16 citations
Semantic Scholar
Assembly principles of the human R2TP chaperone complex reveal the presence of R2T and R2P complexes.
T. V. Seraphim, Nardin Nano, Y. Cheung, Siripat Aluksanasuwan +17 more
2021Structure15 citations Open access
Semantic Scholar
Assembly Principles of the Human R2TP Chaperone Complex Reveal the Presence of R2T and R2P Complexes
W. Houry, T. V. Seraphim
2022The FASEB Journal14 citations Open access
Semantic Scholar
Solution structure of Plasmodium falciparum Hsp90 indicates a high flexible dimer.
N. S. M. Silva, M. Torricillas, K. Minari, Leandro R. S. Barbosa +2 more
2020Archives of Biochemistry and Biophysics14 citations Open access
Semantic Scholar
Mechanism of Amyloidogenesis of a Bacterial AAA+ Chaperone.
S. W. S. Chan, Jason Yau, C. Ing, Kaiyin Liu +11 more
2016Structure14 citations Open access
Semantic Scholar
Comparative studies of the low-resolution structure of two p23 co-chaperones for Hsp90 identified in Plasmodium falciparum genome.
N. S. M. Silva, T. V. Seraphim, K. Minari, Leandro R. S. Barbosa +1 more
2018International Journal of Biological Macromolecules13 citations
Semantic Scholar
Insights on the structural dynamics of Leishmania braziliensis Hsp90 molecular chaperone by small angle X-ray scattering.
T. V. Seraphim, K. P. Silva, P. R. Dores-Silva, Leandro R. S. Barbosa +1 more
2017International Journal of Biological Macromolecules12 citations Open access
Semantic Scholar
Low sequence identity but high structural and functional conservation: The case of Hsp70/Hsp90 organizing protein (Hop/Sti1) of Leishmania braziliensis.
F. A. H. Batista, T. V. Seraphim, C. A. Santos, Marisvanda R Gonzaga +3 more
2016Archives of Biochemistry and Biophysics10 citations Open access
Semantic Scholar
Strategies for purification of the bacteriophage HK97 small and large terminase subunits that yield pure and homogeneous samples that are functional.
Sasha A Weiditch, T. V. Seraphim, W. Houry, V. Kanelis
2019Protein Expression and Purification9 citations
Semantic Scholar
Studies on the effect of the J-domain on the substrate binding domain (SBD) of Hsp70 using a chimeric human J-SBD polypeptide.
Ana O. Tiroli-Cepeda, T. V. Seraphim, G. Pinheiro, D. Souto +4 more
2019International Journal of Biological Macromolecules5 citations Open access
Semantic Scholar
Insights into the full-length SRPK2 structure and its hydrodynamic behavior.
Éverton de Almeida Alves Barbosa, T. V. Seraphim, C. A. Gandin, Leilane Ferreira Teixeira +13 more
2019International Journal of Biological Macromolecules2 citations Open access
Semantic Scholar
Characterization of the granule-associated protein AzPhaP from Azotobacter sp. FA8 as a promising protein-based surfactant.
R. L. Salgado, M. I. B. Aragão, Éverton de Almeida Alves Barbosa, Julia Mayrink Ferreira Alves +8 more
2026International Journal of Biological Macromolecules0 citations Open access
Semantic Scholar
Insights into the effect of the J-domain on the substrate binding domain (SBD) of the 70 kDa heat shock protein, Hsp70, from a chimeric human J-SBD polypeptide
Ana O. Tiroli-Cepeda, T. V. Seraphim, J. Borges, C. H. Ramos
2018bioRxiv0 citations Open access
Semantic Scholar
Structural characterization of plasmodium falciparum Hsp70/Hsp90 organizing protein (HOP)
Dayane Reis, Noeli Soares Melo da Silva, T. V. Seraphim, F. A. H. Batista +1 more
20180 citations
Semantic Scholar
A review of multi-domain and flexible molecular chaperones studies by small-angle X-ray scattering
J. Borges, T. V. Seraphim, P. R. Dores-Silva, Leandro R. S. Barbosa
2016Biophysical Reviews0 citations Open access
Semantic Scholar

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