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Chao-Chen Wang · SciRah

Researcher profile · Semantic Scholar

Chao-Chen Wang

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Chao-Chen Wang — researcher profile on SciRah

h-index: 37
Works: 131
Citations: 6,018

Most-cited papers

CRISPR/Cas9 targeting events cause complex deletions and insertions at 17 sites in the mouse genome
H. Shin, Chao-Chen Wang, H. Lee, K. Yoo +6 more
2017Nature Communications286 citations Open access
Semantic Scholar
Hierarchy within the mammary STAT5-driven Wap super-enhancer
H. Shin, Michaela Willi, Kyung HyunYoo, Xianke Zeng +3 more
2016Nature Genetics263 citations Open access
Semantic Scholar
Enhancer priming by H3K4 methyltransferase MLL4 controls cell fate transition
Chao-Chen Wang, Ji-Eun Lee, Bin-Bin Lai, T. Macfarlan +5 more
2016Proceedings of the National Academy of Sciences of the United States of America229 citations Open access
Semantic Scholar
Identification of H3K4me1-Associated Proteins at Mammalian Enhancers
A. Local, Hui Huang, C. Albuquerque, Namit Singh +10 more
2017Nature Genetics211 citations Open access
Semantic Scholar
Esophageal cancer in high-risk areas of China: research progress and challenges.
Ying-Song Lin, Y. Totsuka, B. Shan, Chao-Chen Wang +6 more
2017Annals of Epidemiology186 citations
Semantic Scholar
UTX inhibition as selective epigenetic therapy against TAL1-driven T-cell acute lymphoblastic leukemia
Aissa Benyoucef, C. Palii, Chao-Chen Wang, Christopher J Porter +13 more
2016Genes & Development115 citations Open access
Semantic Scholar
Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers
Jian Yan, Shi-An A. Chen, A. Local, Tristin Liu +10 more
2018Cell Research114 citations Open access
Semantic Scholar
H3.3K4M destabilizes enhancer H3K4 methyltransferases MLL3/MLL4 and impairs adipose tissue development
Younghoon Jang, Aaron Broun, Chao-Chen Wang, Young-Kwon Park +5 more
2018Nucleic Acids Research110 citations Open access
Semantic Scholar
Changing trends in the prevalence of H. pylori infection in Japan (1908–2003): a systematic review and meta-regression analysis of 170,752 individuals
Chao-Chen Wang, T. Nishiyama, S. Kikuchi, M. Inoue +3 more
2017Scientific Reports108 citations Open access
Semantic Scholar
UTX-guided neural crest function underlies craniofacial features of Kabuki syndrome
Karl B. Shpargel, J. Starmer, Chao-Chen Wang, K. Ge +1 more
2017Proceedings of the National Academy of Sciences of the United States of America86 citations Open access
Semantic Scholar
Histone H3 lysine 4 monomethylation modulates long-range chromatin interactions at enhancers
Jian Yan, Shi-An A. Chen, A. Local, Tristin Liu +10 more
2018Cell Research84 citations Open access
Semantic Scholar
UTX demethylase activity is required for satellite cell-mediated muscle regeneration.
H. Faralli, Chao-Chen Wang, Kiran Nakka, Aissa Benyoucef +9 more
2016Journal of Clinical Investigation82 citations Open access
Semantic Scholar
MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping
Katarzyna Placek, Gang-Qing Hu, Kai-Rong Cui, Dun-Fang Zhang +10 more
2017Nature Immunology79 citations Open access
Semantic Scholar
Fasting‐induced JMJD3 histone demethylase epigenetically activates mitochondrial fatty acid &bgr;‐oxidation
Sunmi Seok, Young-Chae Kim, S. Byun, Sung-E Choi +8 more
2018Journal of Clinical Investigation70 citations Open access
Semantic Scholar
H3K4 methyltransferase activity is required for MLL4 protein stability
Younghoon Jang, Chao-Chen Wang, Lenan Zhuang, Cheng-Yu Liu +1 more
2016Journal of Molecular Biology56 citations Open access
Semantic Scholar
Genome-wide association meta-analysis identifies GP2 gene risk variants for pancreatic cancer
Ying-Song Lin, M. Nakatochi, Y. Hosono, H. Ito +82 more
2020Nature Communications53 citations Open access
Semantic Scholar
The Kiddie Schedule for Affective Disorders and Schizophrenia Present and Lifetime Version (K-SADS-PL) for DSM-5: A validation for neurodevelopmental disorders in Japanese outpatients.
T. Nishiyama, S. Sumi, Hiroto Watanabe, Futoshi Suzuki +7 more
2019Comprehensive Psychiatry46 citations Open access
Semantic Scholar
Prediction model for pancreatic cancer risk in the general Japanese population
M. Nakatochi, Ying-Song Lin, H. Ito, K. Hara +21 more
2018PLoS ONE40 citations Open access
Semantic Scholar
Smoking and colorectal cancer: A pooled analysis of 10 population‐based cohort studies in Japan
S. Akter, Z. Islam, T. Mizoue, N. Sawada +19 more
2020International Journal of Cancer37 citations Open access
Semantic Scholar
Perceived Stress and Colorectal Cancer Incidence: The Japan Collaborative Cohort Study
Norimasa Kikuchi, T. Nishiyama, Takayuki Sawada, Chao-Chen Wang +4 more
2017Scientific Reports37 citations Open access
Semantic Scholar
A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development
Ying Xiao, Daniel T. Thoresen, L. Miao, Jonathan S. Williams +4 more
2016PLoS Genetics36 citations Open access
Semantic Scholar
Histone Demethylase KDM6A Controls the Mammary Luminal Lineage through Enzyme-Independent Mechanisms
K. Yoo, Sumin Oh, Keunsoo Kang, Chao-Chen Wang +3 more
2016Molecular and Cellular Biology36 citations Open access
Semantic Scholar
Histone demethylases UTX and JMJD3 are required for NKT cell development in mice
Daniel L. Northrup, Ryoji Yagi, Kai-Rong Cui, W. Proctor +7 more
2017Cell & Bioscience31 citations Open access
Semantic Scholar
Mutation frequency is not increased in CRISPR–Cas9-edited mice
Michaela Willi, Harold E. Smith, Chao-Chen Wang, Cheng-Yu Liu +1 more
2018Nature Methods30 citations
Semantic Scholar
Lifetime incidence risk for gastric cancer in the Helicobacter pylori ‐infected and uninfected population in Japan: A Monte Carlo simulation study
S. Kawai, Chao-Chen Wang, Ying-Song Lin, Tae Sasakabe +2 more
2021International Journal of Cancer26 citations Open access
Semantic Scholar
Alpinetin promotes hair regeneration via activating hair follicle stem cells
Xiaojiao Fan, Jing Chen, Ya-Jun Zhang, Siyi Wang +7 more
2022Chinese Medicine25 citations Open access
Semantic Scholar
Functional assessment of CTCF sites at cytokine-sensing mammary enhancers using CRISPR/Cas9 gene editing in mice
H. Lee, Michaela Willi, Chao-Chen Wang, C. Yang +3 more
2017Nucleic Acids Research25 citations Open access
Semantic Scholar
Prevalence and predictors of prediabetes and diabetes among adults in Palau: population-based national STEPS survey
E. Hilawe, Chi-Fa Chiang, H. Yatsuya, Chao-Chen Wang +9 more
2016Nagoya journal of medical science25 citations
Semantic Scholar
huARdb: human Antigen Receptor database for interactive clonotype-transcriptome analysis at the single-cell level
Li-Ze Wu, Ziwei Xue, Siqian Jin, Jin-Chun Zhang +9 more
2021Nucleic Acids Res.24 citations Open access
Semantic Scholar
Similarities and differences between coronary heart disease and stroke in the associations with cardiovascular risk factors: The Japan Collaborative Cohort Study.
Masaaki Matsunaga, H. Yatsuya, H. Iso, Kentarou Yamashita +8 more
2017Atherosclerosis23 citations Open access
Semantic Scholar
Differential cytokine sensitivities of STAT5-dependent enhancers rely on Stat5 autoregulation
Michaela Willi, K. Yoo, Chao-Chen Wang, Z. Trajanoski +1 more
2016Nucleic Acids Research23 citations Open access
Semantic Scholar
Comparison of the detection of Helicobacter pylori infection by commercially available serological testing kits and the 13C-urea breath test.
S. Kawai, Kensuke Arai, Ying-Song Lin, T. Nishiyama +4 more
2019Journal of Infection and Chemotherapy21 citations
Semantic Scholar
Revolutionizing Drug Discovery: The Impact of Distinct Designs and Biosensor Integration in Microfluidics-Based Organ-on-a-Chip Technology
Shengxi Yuan, Hui-Pu Yuan, David C. Hay, Huan Hu +1 more
2024Biosensors20 citations Open access
Semantic Scholar
Genome-wide association meta-analysis and Mendelian randomization analysis confirm the influence of ALDH2 on sleep durationin the Japanese population.
T. Nishiyama, M. Nakatochi, A. Goto, M. Iwasaki +46 more
2019Sleep20 citations
Semantic Scholar
Body mass index and esophageal and gastric cancer: A pooled analysis of 10 population‐based cohort studies in Japan
Y. Koyanagi, K. Matsuo, H. Ito, Chao-Chen Wang +15 more
2023Cancer Science18 citations Open access
Semantic Scholar
l-arginine supplementation improved neonatal outcomes in pregnancies with hypertensive disorder or intrauterine growth restriction: A systematic review and meta-analysis of randomized controlled trials.
Lianbin Xu, Xinhui Wang, Chao-Chen Wang, Wenyuan Li +1 more
2022Clinical Nutrition18 citations
Semantic Scholar
Assessment of locomotive syndrome among older individuals: a confirmatory factor analysis of the 25-question Geriatric Locomotive Function Scale
Chao-Chen Wang, T. Ikemoto, A. Hirasawa, Y. Arai +2 more
2020PeerJ18 citations Open access
Semantic Scholar
Metronidazole for Helicobacter pylori eradication therapy among children and adolescents in Japan: Overcoming controversies and concerns
M. Okuda, Ying-Song Lin, Chao-Chen Wang, T. Kakiuchi +1 more
2019Helicobacter18 citations
Semantic Scholar
scCDC: a computational method for gene-specific contamination detection and correction in single-cell and single-nucleus RNA-seq data
Weijian Wang, Yi-Hui Cen, Zezhen Lu, Yue-Qing Xu +5 more
2022bioRxiv17 citations Open access
Semantic Scholar
Alcohol consumption and breast cancer risk in Japan: A pooled analysis of eight population‐based cohort studies
M. Iwase, K. Matsuo, Y. Koyanagi, H. Ito +15 more
2021International Journal of Cancer17 citations Open access
Semantic Scholar
Lineage-specific and non-specific cytokine-sensing genes respond differentially to the master regulator STAT5
Xianke Zeng, Michaela Willi, H. Shin, L. Hennighausen +1 more
2016Cell Reports17 citations Open access
Semantic Scholar
The influence of personality and perceived stress on the development of breast cancer: 20-year follow-up of 29,098 Japanese women
Takayuki Sawada, T. Nishiyama, Norimasa Kikuchi, Chao-Chen Wang +5 more
2016Scientific Reports17 citations Open access
Semantic Scholar
MED12 loss activates endogenous retroelements to sensitise immunotherapy in pancreatic cancer
Yingying Tang, Shijie Tang, Wenjuan Yang, Zheng-Yan Zhang +12 more
2024Gut16 citations
Semantic Scholar
Low-intensity cigarette smoking and mortality risks: a pooled analysis of prospective cohort studies in Japan.
M. Inoue-Choi, N. Freedman, Eiko Saito, Shiori Tanaka +22 more
2021International Journal of Epidemiology15 citations Open access
Semantic Scholar
Treatment persistence of interleukin-17 inhibitor class drugs among patients with psoriasis in Japan: a retrospective database study
Chao-Chen Wang, H. Torisu-Itakura, T. Hanada, T. Matsuo +3 more
2023Journal of dermatological treatment (Print)12 citations Open access
Semantic Scholar
Hair Graying Regulators Beyond Hair Follicle
Jing Chen, Yixin Zheng, Chen Hu, Xue-Xiao Jin +3 more
2022Frontiers in Physiology11 citations Open access
Semantic Scholar
Genetically Engineered Light‐Responsive In Situ Hydrogels for Immunomodulation and Multimodal Therapy in Metastatic Triple‐Negative Breast Cancer
Xinchen Shen, Jiajia Zhang, Junhan Ou, Zi-Heng Bai +8 more
2025Advancement of science10 citations Open access
Semantic Scholar
Study on the mechanism of brain injury caused by acute diquat poisoning based on metabolomics.
Chao-Chen Wang, Huihua Hu, Junzhao Liu, Xia Rong +2 more
2024Toxicology and Applied Pharmacology10 citations
Semantic Scholar
A universal co‐expression gene network and prognostic model for hepatic–biliary–pancreatic cancers identified by integrative analyses
Jing Zhang, Juan Xiao, Yi-Xuan Wang, Xiao Zheng +2 more
2022FEBS Open Bio10 citations Open access
Semantic Scholar
Super‐Enhancer Reprograming Driven by SOX9 and TCF7L2 Represents Transcription‐Targeted Therapeutic Vulnerability for Treating Gallbladder Cancer
Siyuan Yan, Zhaonan Liu, Teng Wang, Yi Sui +19 more
2024Advancement of science9 citations Open access
Semantic Scholar

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