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M. Dostálek · SciRah

Researcher profile · Semantic Scholar

M. Dostálek

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M. Dostálek — researcher profile on SciRah

h-index: 24
Works: 81
Citations: 2,285

Most-cited papers

Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
J. Regula, Peter Lundh von Leithner, R. Foxton, V. Barathi +14 more
2016EMBO Molecular Medicine288 citations Open access
Semantic Scholar
Pharmacokinetics, Pharmacodynamics and Physiologically-Based Pharmacokinetic Modelling of Monoclonal Antibodies
M. Dostálek, I. Gardner, B. Gurbaxani, Rachel H. Rose +1 more
2013Clinical Pharmacokinetics219 citations
Semantic Scholar
Targeting key angiogenic pathways with a bispecific CrossMAb optimized for neovascular eye diseases
J. Regula, Peter Lundh von Leithner, R. Foxton, V. Barathi +14 more
2017EMBO Molecular Medicine189 citations Open access
Semantic Scholar
Molecular and clinical spectrum of type I plasminogen deficiency: A series of 50 patients.
K. Tefs, M. Gueorguieva, J. Klammt, C. Allen +29 more
2006Blood157 citations Open access
Semantic Scholar
Significantly reduced cytochrome P450 3A4 expression and activity in liver from humans with diabetes mellitus
M. Dostálek, M. Court, B. Yan, F. Akhlaghi
2011British Journal of Pharmacology137 citations Open access
Semantic Scholar
Insulin Resistance, Ceramide Accumulation, and Endoplasmic Reticulum Stress in Human Chronic Alcohol-Related Liver Disease
Lisa Longato, K. Ripp, M. Setshedi, M. Dostálek +4 more
2012Oxidative Medicine and Cellular Longevity133 citations Open access
Semantic Scholar
Effect of Diabetes Mellitus on Pharmacokinetic and Pharmacodynamic Properties of Drugs
M. Dostálek, F. Akhlaghi, Martina Puzanovova
2012Clinical Pharmacokinetics126 citations Open access
Semantic Scholar
Expression and purification of orphan cytochrome P450 4X1 and oxidation of anandamide
Katarina Stark, M. Dostálek, F. Guengerich
2008The FEBS Journal94 citations Open access
Semantic Scholar
Development of Oxidative Stress by Cytochrome P450 Induction in Rodents Is Selective for Barbiturates and Related to Loss of Pyridine Nucleotide-dependent Protective Systems*
M. Dostálek, Klarissa D. Hardy, G. Milne, J. Morrow +8 more
2008Journal of Biological Chemistry81 citations Open access
Semantic Scholar
Insulin resistance, ceramide accumulation and endoplasmic reticulum stress in experimental chronic alcohol-induced steatohepatitis.
Teresa Ramirez, Lisa Longato, M. Dostálek, M. Tong +2 more
2013Alcohol and Alcoholism76 citations Open access
Semantic Scholar
Simulation of Monoclonal Antibody Pharmacokinetics in HumansUsing a Minimal Physiologically Based Model
Lin-Zhong Li, I. Gardner, M. Dostálek, M. Jamei
2014AAPS Journal61 citations Open access
Semantic Scholar
Are endosomal trafficking parameters better targets for improving mAb pharmacokinetics than FcRn binding affinity?
B. Gurbaxani, M. Dostálek, I. Gardner
2013Molecular Immunology54 citations
Semantic Scholar
In Vivo Oxidative Damage in Rats Is Associated with Barbiturate Response but Not Other Cytochrome P450 Inducers
M. Dostálek, J. D. Brooks, Klarissa D. Hardy, G. Milne +4 more
2007Molecular Pharmacology52 citations
Semantic Scholar
Diabetes Mellitus Reduces Activity of Human UDP-Glucuronosyltransferase 2B7 in Liver and Kidney Leading to Decreased Formation of Mycophenolic Acid Acyl-Glucuronide Metabolite
M. Dostálek, M. Court, Suwagmani Hazarika, F. Akhlaghi
2011Drug Metabolism And Disposition46 citations Open access
Semantic Scholar
Development and validation of a sensitive, simple, and rapid method for simultaneous quantitation of atorvastatin and its acid and lactone metabolites by liquid chromatography-tandem mass spectrometry (LC-MS/MS)
J. Macwan, I. Ionita, M. Dostálek, F. Akhlaghi
2011Analytical and Bioanalytical Chemistry46 citations Open access
Semantic Scholar
HPLC determination of midazolam and its three hydroxy metabolites in perfusion medium and plasma from rats.
J. Juřica, M. Dostálek, J. Konečnỳ, Z. Glatz +2 more
2007Journal of chromatography. B, Analytical technologies in the biomedical and life sciences44 citations
Semantic Scholar
Effect of St John's wort (Hypericum perforatum) on cytochrome P-450 activity in perfused rat liver.
M. Dostálek, Jana Pistovčáková, J. Juřica, Josef Tomandl +3 more
2005Life Science44 citations
Semantic Scholar
Pharmacokinetic de-risking tools for selection of monoclonal antibody lead candidates
M. Dostálek, T. Prueksaritanont, R. Kelley
2017mAbs43 citations Open access
Semantic Scholar
D-Amino Acid Oxidase Generates Agonists of the Aryl Hydrocarbon Receptor from D-Tryptophan
L. P. Nguyen, Erin L. Hsu, G. Chowdhury, M. Dostálek +2 more
2009Chemical Research in Toxicology43 citations Open access
Semantic Scholar
Structural Identification of Diindole Agonists of the Aryl Hydrocarbon Receptor Derived from Degradation of Indole-3-pyruvic Acid
G. Chowdhury, M. Dostálek, Erin L. Hsu, L. Nguyen +3 more
2009Chemical Research in Toxicology41 citations Open access
Semantic Scholar
St John's Wort (Hypericum Perforatum L.)
M. Dostálek, Anna Stark
201240 citations
Semantic Scholar
The Concentration of Cyclosporine Metabolites Is Significantly Lower in Kidney Transplant Recipients With Diabetes Mellitus
F. Akhlaghi, M. Dostálek, P. Falck, Anisha E. Mendonza +3 more
2012Therapeutic Drug Monitoring34 citations Open access
Semantic Scholar
Effect of methamphetamine on cytochrome P450 activity
M. Dostálek, J. Juřica, J. Pistovčáková, M. Hanesová +3 more
2007Xenobiotica; the fate of foreign compounds in biological systems31 citations
Semantic Scholar
Human Liver Mitochondrial Cytochrome P450 2D6: Individual Variations and Implications in Drug Metabolism
Michelle L. Cook Sangar, H. Anandatheerthavarada, Weigang Tang, S. K. Prabu +4 more
2009The FEBS Journal29 citations Open access
Semantic Scholar
Effect of Diabetes Mellitus on Pharmacokinetic and Pharmacodynamic Properties of Drugs
M. Dostálek, F. Akhlaghi, Martina Puzanovova
201224 citations
Semantic Scholar
Diabetes mellitus reduces the clearance of atorvastatin lactone: results of a population pharmacokinetic analysis in renal transplant recipients and in vitro studies using human liver microsomes.
M. Dostálek, W. Sam, Komal R. Paryani, J. Macwan +2 more
2012Clinical Pharmacokinetics22 citations Open access
Semantic Scholar
Development and validation of a rapid and sensitive assay for simultaneous quantification of midazolam, 1'-hydroxymidazolam, and 4-hydroxymidazolam by liquid chromatography coupled to tandem mass-spectrometry.
M. Dostálek, J. Macwan, Shripad D. Chitnis, I. Ionita +1 more
2010Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20 citations Open access
Semantic Scholar
Tiagabine Treatment is Associated with Neurochemical, Immune and Behavioural Alterations in the Olfactory Bulbectomized Rat Model of Depression
J. Pistovčáková, M. Dostálek, A. Šulcová, D. Jezova
2008Pharmacopsychiatry20 citations
Semantic Scholar
Diabetes Mellitus Reduces the Clearance of Atorvastatin Lactone
M. Dostálek, W. Sam, Komal R. Paryani, J. Macwan +2 more
2012Clinical Pharmacokinetics19 citations Open access
Semantic Scholar
Are contrast sensitivity functions impaired in insulin dependent diabetics without diabetic retinopathy?
Vladimír Liška, M. Dostálek
1999Acta medica17 citations Open access
Semantic Scholar
Inosine Monophosphate Dehydrogenase Expression and Activity are Markedly Lower in Kidney Transplant Recipients with Diabetes Mellitus
M. Dostálek, R. Gohh, F. Akhlaghi
2013Therapeutic Drug Monitoring15 citations Open access
Semantic Scholar
Effect of methamphetamine on the pharmacokinetics of dextromethorphan and midazolam in rats
M. Dostálek, Eva McCaskey Hadašová, Mariana Hanesová, Jana Pistovčáková +4 more
2005European journal of drug metabolism and pharmacokinetics11 citations
Semantic Scholar
The effect of St John's wort (hypericum perforatum) on cytochrome p450 1a2 activity in perfused rat liver.
M. Dostálek, J. Pistovčáková, J. Juřica, A. Šulcová +1 more
2011Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia8 citations Open access
Semantic Scholar
Single-dose and steady state pharmacokinetics of CSA and two main primary metabolites, AM1 and AM4n in patients with rheumatic/autoimmune diseases.
David Suchy, M. Dostálek, I. Peřinová, H. Brozmanova +3 more
2011Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia5 citations Open access
Semantic Scholar
Influence of Artificially Generated Interocular Blur Difference on Fusion Stability Under Vergence Stress
M. Dostálek, K. Fliegel, L. Dušek, T. Lukeš +4 more
2019Journal of Eye Movement Research4 citations Open access
Semantic Scholar
Accommodation and vergence infrared measurement using hologram stimulus
T. Jindra, J. Dusek, M. Dostálek, P. Fiala +1 more
2011Other Conferences2 citations
Semantic Scholar
[Ligneous conjunctivitis: complication of inborn plasminogen deficiency (a case report)].
M. Dostálek, J. Krásný, I. Špička, J. Šach
2005Czech and Slovak Ophthalmology2 citations
Semantic Scholar
Some recruitment aspects of population photoscreening of amblyogenic factors at children younger one year.
M. Dostálek, J. Benesova
2002Acta medica2 citations Open access
Semantic Scholar
Dichoptic contrast masking during relative convergence training
M. Dostálek, P. Betlachová, R. Autrata
20121 citations
Semantic Scholar
Spatial holograms in measuring of eye vergence and accommodation dynamics
T. Jindra, J. Dusek, M. Dostálek, P. Fiala +1 more
2011E-Health and Bioengineering Conference1 citations
Semantic Scholar
The influence of gender on metabolic activity of enzymaticsystem of cytochrome P450 in the model of isolated perfused ratliver.
L. Zahradníková, O. Zendulka, J. Juřica, M. Dostálek +1 more
20061 citations
Semantic Scholar
Effect of Acute and Repeated Administration of Methamphetamine on the Activity of CYP2D in Isolated Perfused Rat Liver
M. Dostálek, J. Pistovčáková, V. Mináriková, J. Juřica +2 more
20051 citations Open access
Semantic Scholar
Effect of methamphetamine and fluoxetine combination onmetabolic activity of CYP2D1 in isolated perfused liver
M. Dostálek, J. Slíva, E. Hadašová, J. Tomandl
20031 citations
Semantic Scholar
[Propane-oxidizing bacteria].
M. Dostálek
1954Chekhoslovatskaia biologiia1 citations
Semantic Scholar
Synkinesis of vergence and accommodation in accommodative esotropia
M. Dostálek
20200 citations
Semantic Scholar
E.M.A.N. (Eye Movement and Accommodation Analyzer) device for vergence accommodation synkinesis recording and analysis
M. Dostálek, J. Dusek
20200 citations
Semantic Scholar
Scleroplasty surgery in children
R. Autrata, I. Krejčířová, L. Griščíková, Martin Komínek +1 more
20190 citations
Semantic Scholar
Excimer laser for myopic anisometropic amblyopia in pediatric patients - Long term results
R. Autrata, I. Krejčířová, L. Griščíková, B. Žajdlíková +2 more
20180 citations
Semantic Scholar
Studie ATOM I, ATOM II a SHIELD
T. Krejzková, M. Dostálek, Andrea Martínková, I. Krejčířová +2 more
20170 citations
Semantic Scholar
Glutathione S‐Transferases
M. Dostálek, Anna Stark
20120 citations
Semantic Scholar

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F. Akhlaghi×11
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