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M. Valadares · SciRah

Researcher profile · Semantic Scholar

M. Valadares

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M. Valadares — researcher profile on SciRah

h-index: 31
Works: 169
Citations: 3,352

Most-cited papers

Ascorbic acid encapsulated into negatively charged liposomes exhibits increased skin permeation, retention and enhances collagen synthesis by fibroblasts
Lorena Maione-Silva, E. G. de Castro, T. L. Nascimento, E. Cintra +4 more
2019Scientific Reports128 citations Open access
Semantic Scholar
Ecotoxicological assessment of glyphosate‐based herbicides: Effects on different organisms
Laís de Brito Rodrigues, R. de Oliveira, F. Abe, L. Brito +5 more
2017Environmental Toxicology and Chemistry89 citations
Semantic Scholar
Increased Nose-to-Brain Delivery of Melatonin Mediated by Polycaprolactone Nanoparticles for the Treatment of Glioblastoma
E. D. de Oliveira, T. L. Nascimento, M. A. Salomão, A. C. Garcia da Silva +2 more
2019Pharmaceutical Research84 citations
Semantic Scholar
Intravenous delivery of a liposomal formulation of voriconazole improves drug pharmacokinetics, tissue distribution, and enhances antifungal activity
Danillo F. M. C. Veloso, N. Benedetti, Renato I. Ávila, Thiago S. A. Bastos +5 more
2018Drug Delivery58 citations Open access
Semantic Scholar
In vitro safety and efficacy evaluations of a complex botanical mixture of Eugenia dysenterica DC. (Myrtaceae): Prospects for developing a new dermocosmetic product.
L. Moreira, R. de Ávila, Danillo F. M. C. Veloso, T. Pedrosa +6 more
2017Toxicology in Vitro43 citations Open access
Semantic Scholar
Effect of photobiomodulation therapy on reducing the chemo-induced oral mucositis severity and on salivary levels of CXCL8/interleukin 8, nitrite, and myeloperoxidase in patients undergoing hematopoietic stem cell transplantation: a randomized clinical trial
D. Salvador, D. Soave, N. T. Sacono, E. F. de Castro +6 more
2017Lasers in Medical Science39 citations
Semantic Scholar
Paclitaxel-Loaded Lipid-Coated Magnetic Nanoparticles for Dual Chemo-Magnetic Hyperthermia Therapy of Melanoma
R. R. Oliveira, E. Cintra, A. Sousa-Junior, L. Moreira +6 more
2023Pharmaceutics34 citations Open access
Semantic Scholar
Randomized clinical trial of a mucoadhesive formulation containing curcuminoids (Zingiberaceae) and Bidens pilosa Linn (Asteraceae) extract (FITOPROT) for prevention and treatment of oral mucositis - phase I study.
Edvande Xavier dos Santos, D. Arantes, Angélica Ferreira Oton Leite, A. Batista +5 more
2018Chemico-Biological Interactions33 citations
Semantic Scholar
Mucopenetrating lipoplexes modified with PEG and hyaluronic acid for CD44-targeted local siRNA delivery to the lungs
Ana Paula Maia Almeida, Gabrielly Bernardes Rodrigues Damaceno, A. Carneiro, A. Bohr +4 more
2019Journal of Biomaterials Applications31 citations
Semantic Scholar
In vitro assessment of skin sensitization, photosensitization and phototoxicity potential of commercial glyphosate-containing formulations.
R. de Ávila, G. C. Teixeira, Danillo F. M. C. Veloso, L. Moreira +2 more
2017Toxicology in Vitro31 citations Open access
Semantic Scholar
Cost-effectiveness randomized clinical trial on the effect of photobiomodulation therapy for prevention of radiotherapy-induced severe oral mucositis in a Brazilian cancer hospital setting
Allisson Filipe Lopes Martins, T. E. Nogueira, M. O. Morais, Sebastião Silvério de Sousa-Neto +5 more
2020Supportive Care in Cancer29 citations
Semantic Scholar
Photobiomodulation reduces the impact of radiotherapy on oral health-related quality of life due to mucositis-related symptoms in head and neck cancer patients
A. F. L. Martins, M. O. Morais, Sebastião Silvério de Sousa-Neto, A. D. de Jesus +6 more
2020Lasers in Medical Science28 citations
Semantic Scholar
Folate-Targeted PEGylated Magnetoliposomes for Hyperthermia-Mediated Controlled Release of Doxorubicin
E. Cintra, T. G. Hayasaki, A. Sousa-Junior, A. C. G. Silva +4 more
2022Frontiers in Pharmacology27 citations Open access
Semantic Scholar
Effect of photobiomodulation on the severity of oral mucositis and molecular changes in head and neck cancer patients undergoing radiotherapy: a study protocol for a cost-effectiveness randomized clinical trial
A. F. L. Martins, T. E. Nogueira, M. O. Morais, A. F. Oton-Leite +5 more
2019Trials27 citations Open access
Semantic Scholar
Chemopreventive effects of FITOPROT against 5‐fluorouracil‐induced toxicity in HaCaT cells
Edvande Xavier dos Santos, A. C. Garcia da Silva, R. de Ávila, A. Batista +5 more
2018Life Science27 citations
Semantic Scholar
Antiproliferative Activity and VEGF Expression Reduction in MCF7 and PC-3 Cancer Cells by Paclitaxel and Imatinib Co-encapsulation in Folate-Targeted Liposomes
Marco Júnio Peres-Filho, A. P. dos Santos, T. L. Nascimento, R. de Ávila +3 more
2017AAPS PharmSciTech25 citations
Semantic Scholar
Topotecan‐loaded lipid nanoparticles as a viable tool for the topical treatment of skin cancers
J. Venâncio, L. Andrade, N. Esteves, L. Brito +6 more
2017The Journal of pharmacy and pharmacology24 citations
Semantic Scholar
Mucoadhesive formulation containing Curcuma longa L. reduces oral mucositis induced by 5‐fluorouracil in hamsters
T. R. Schmidt, M. Curra, V. Wagner, M. A. Martins +5 more
2019Phytotherapy Research23 citations
Semantic Scholar
Brazil Moves Toward the Replacement of Animal Experimentation
R. de Ávila, M. Valadares
2019Alternatives to laboratory animals : ATLA22 citations
Semantic Scholar
The 21st Century movement within the area of skin sensitization assessment: From the animal context towards current human-relevant in vitro solutions.
R. de Ávila, M. Lindstedt, M. Valadares
2019Regulatory toxicology and pharmacology : RTP22 citations
Semantic Scholar
Near Infrared Biomimetic Hybrid Magnetic Nanocarrier for MRI-Guided Thermal Therapy
J. V. R. Rocha, R. Krause, Carlos Eduardo Ribeiro, N. C. de Almeida Oliveira +9 more
2024ACS Applied Materials and Interfaces21 citations Open access
Semantic Scholar
Carbendazim induces death in alveolar epithelial cells: A comparison between submerged and at the air-liquid interface cell culture.
B. F. Tollstadius, A. C. Garcia da Silva, B. Pedralli, M. Valadares
2019Toxicology in Vitro21 citations Open access
Semantic Scholar
Radical Scavenger Capacity of Jabuticaba Fruit (Myrciaria cauliflora) and Its Biological Effects in Hypertensive Rats
C. G. de Souza, Daniela Medeiros Lobo de Andrade, J. Jordão, R. de Ávila +6 more
2017Oxidative Medicine and Cellular Longevity20 citations Open access
Semantic Scholar
New pyrazole derivative 5‐[1‐(4‐fluorophenyl)‐1H‐pyrazol‐4‐yl]‐2H‐tetrazole: synthesis and assessment of some biological activities
L. P. de Oliveira, Daiany Priscilla Bueno da Silva, I. F. Florentino, J. Fajemiroye +11 more
2017Chemical Biology and Drug Design20 citations
Semantic Scholar
Toxicity evaluation of the photoprotective compound LQFM048: Eye irritation, skin toxicity and genotoxic endpoints.
R. de Ávila, Marcelo de Sousa Vieira, M. Gaeti, L. Moreira +6 more
2017Toxicology20 citations Open access
Semantic Scholar
The Effect of Photobiomodulation on Nitrite and Inflammatory Activity in Radiotherapy‐Induced Oral Mucositis: A Randomized Clinical Trial
A. F. L. Martins, M. O. Morais, S. S. Sousa-Neto, A. F. Oton-Leite +6 more
2020Lasers in Surgery and Medicine19 citations
Semantic Scholar
A novel chalcone derivative, LQFM064, induces breast cancer cells death via p53, p21, KIT and PDGFRA
Bruna Lannuce Silva Cabral, A. C. Garcia da Silva, R. de Ávila, A. P. Cortez +8 more
2017European Journal of Pharmaceutical Sciences19 citations
Semantic Scholar
Anti-inflammatory effect of a new piperazine derivative: (4-methylpiperazin-1-yl)(1-phenyl-1H-pyrazol-4-yl)methanone
Daniel C. Batista, Daiany P. B. Silva, I. F. Florentino, C. Cardoso +7 more
2017InflammoPharmacology19 citations
Semantic Scholar
Punicalagin triggers ergosterol biosynthesis disruption and cell cycle arrest in Cryptococcus gattii and Candida albicans
Thaísa C Silva, R. de Ávila, A. Zara, Andressa Santana Santos +5 more
2020Brazilian Journal of Microbiology18 citations Open access
Semantic Scholar
Qualitative and quantitative evaluation of Fetal Bovine Serum composition: toward ethical and best quality in vitro science
Ana Clara Silva Stival, A. C. Garcia da Silva, M. Valadares
2025NAM journal16 citations Open access
Semantic Scholar
Effects of a mucoadhesive phytomedicine (Curcuma longa L. and Bidens pilosa L.) on radiotherapy-induced oral mucositis and quality of life of patients undergoing head and neck cancer treatment: randomized clinical trial
A. F. L. Martins, Carlos H Pereira, M. O. Morais, Sebastião Silvério de Sousa-Neto +4 more
2023Supportive Care in Cancer16 citations
Semantic Scholar
Evaluation of in vitro testing strategies for hazard assessment of the skin sensitization potential of “real‐life” mixtures: The case of henna‐based hair‐colouring products containing p‐phenylenediamine
R. de Ávila, Danillo F. M. C. Veloso, G. C. Teixeira, T. Rodrigues +5 more
2019Contact Dermatitis16 citations
Semantic Scholar
Application of the adverse outcome pathway framework for investigating skin sensitization potential of nanomaterials using new approach methods
S. F. Bezerra, Bruna Santos Rodrigues, A. C. G. Silva, Renato I. Ávila +5 more
2020Contact Dermatitis15 citations
Semantic Scholar
Electrochemical remediation of amoxicillin: detoxification and reduction of antimicrobial activity.
L. Brito, L. F. Garcia, Marcos Pereira Caetano, G. S. Lobón +10 more
2018Chemico-Biological Interactions15 citations Open access
Semantic Scholar
Exposure to acetaminophen impairs vasodilation, increases oxidative stress and changes arterial morphology of rats
H. Porto, M. Grando, L. Ramalho, M. Valadares +3 more
2019Archives of Toxicology14 citations
Semantic Scholar
In vitro and in vivo cytotoxicity assessment of glyphosate and imazethapyr-based herbicides and their association
G. Costa, A. Fernandes, T. Santos, L. Brito +6 more
2022Journal of Toxicology and Environmental Health, Part A13 citations Open access
Semantic Scholar
A new corneal epithelial biomimetic 3D model for in vitro eye toxicity assessment: Development, characterization and applicability.
A. C. G. da Silva, A. Chialchia, E. G. de Castro, M. R. L. E. Silva +4 more
2020Toxicology in Vitro13 citations
Semantic Scholar
Protective effect of sucupira oil nanoemulsion against oxidative stress in UVA‐irradiated HaCaT cells
M. T. Pacheco, A. C. G. Silva, T. L. Nascimento, D. G. A. Diniz +2 more
2019The Journal of pharmacy and pharmacology13 citations
Semantic Scholar
Safety and efficacy of a mucoadhesive phytomedication containing curcuminoids and Bidens pilosa L. extract in the prevention and treatment of radiochemotherapy‐induced oral mucositis: Triple‐blind, randomized, placebo‐controlled, clinical trial
D. Arantes, A. C. G. Silva, N. A. M. Freitas, E. Lima +4 more
2021Head and Neck12 citations
Semantic Scholar
4-Nerolidylcatechol: apoptosis by mitochondrial mechanisms with reduction in cyclin D1 at G0/G1 stage of the chronic myelogenous K562 cell line
P. L. Benfica, R. de Ávila, B. dos Santos Rodrigues, A. P. Cortez +5 more
2017Pharmaceutical Biology12 citations Open access
Semantic Scholar
Pharmacological evaluation and molecular docking of new di‐tert‐butylphenol compound, LQFM‐091, a new dual 5‐LOX/COX inhibitor
R. C. Lino, Daiany Priscilla Bueno da Silva, I. F. Florentino, D. D. da Silva +14 more
2017European Journal of Pharmaceutical Sciences12 citations
Semantic Scholar
The novel piperazine-containing compound LQFM018: Necroptosis cell death mechanisms, dopamine D4 receptor binding and toxicological assessment.
Fabiana Bettanin Costa, A. P. Cortez, R. de Ávila, F. S. de Carvalho +13 more
2018Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie10 citations
Semantic Scholar
Human 3D Lung Cancer Tissue Photothermal Therapy Using Zn- and Co-Doped Magnetite Nanoparticles
Edynara Cruz de Moraes, Marcella Miranda Siqueira Furtuoso Rodrigues, Rafaela Campos de Menezes, Marcus Vinícius-Araújo +2 more
2025ACS Biomaterials Science & Engineering9 citations Open access
Semantic Scholar
Anxiolytic- and antidepressant-like effects of new phenylpiperazine derivative LQFM005 and its hydroxylated metabolite in mice.
L. K. da Silva Moreira, R. Silva, D. D. da Silva, Mirella Andrade Silva Mendes +14 more
2021Behavioural Brain Research9 citations
Semantic Scholar
Assessing Agricultural Toxicity in Brazil: Advances and Opportunities in the 21st Century.
A. C. Garcia da Silva, Isabelly Sousa, Thais Rosa dos Santos, M. Valadares
2020Toxicological Sciences9 citations
Semantic Scholar
Mechanistic-based non-animal assessment of eye toxicity: Inflammatory profile of human keratinocytes cells after exposure to eye damage/irritant agents.
A. C. Garcia da Silva, A. Chialchia, R. de Ávila, M. Valadares
2018Chemico-Biological Interactions9 citations
Semantic Scholar
Oral mucositis management with photobiomodulation, Bidens pilosa L. (Asteraceae) and Curcuma longa L. (Zingiberaceae), the FITOPROT herbal medicine, and its influence on inflammatory cytokine levels: a randomized clinical trial
Carlos H Pereira, A. F. L. Martins, M. O. Morais, Sebastião Silvério de Sousa-Neto +7 more
2024Supportive Care in Cancer8 citations
Semantic Scholar
Mitochondrial impairment related to the immunotoxicity of the herbicides clomazone, glyphosate and sulfentrazone in THP-1 cells.
L. Cestonaro, A. C. Garcia da Silva, S. C. Garcia, M. Valadares +1 more
2024Toxicological Research8 citations
Semantic Scholar
Non-animal approaches for photoallergenicity safety assessment: Needs and perspectives for the toxicology for the 21st century.
R. de Ávila, M. Aleksic, Bin Zhu, Jin Li +2 more
2023Regulatory toxicology and pharmacology : RTP8 citations Open access
Semantic Scholar
Curcuma longa L. Effects on Akt/mTOR Pathway and NF-κB Expression During Skin Wound Healing: An Immunohistochemical Study
C. K. Danilevicz, V. Wagner, N. Ferreira, H. Bock +8 more
2021Applied immunohistochemistry & molecular morphology (Print)8 citations
Semantic Scholar

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R. de Ávila×16
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A. Batista×13
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