Timothy J. Eisen

Most-cited papers

1. A subset of platinum-containing chemotherapeutic agents kill cells by inducing ribosome biogenesis stress rather than by engaging a DNA damage response

   P. M. Bruno, Yunpeng Liu, Ga-Young Park, J. Murai +6 more

   2017Nature Medicine454 citations Open access

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2. The Dynamics of Cytoplasmic mRNA Metabolism

   Timothy J. Eisen, Stephen W. Eichhorn, Alexander O. Subtelny, Kathy S Lin +3 more

   2019bioRxiv154 citations Open access

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3. Nanomolar inhibition of SARS-CoV-2 infection by an unmodified peptide targeting the prehairpin intermediate of the spike protein

   Kailu Yang, Chu-Chu Wang, Alex J. B. Kreutzberger, Ravi Ojha +16 more

   2022bioRxiv41 citations Open access

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4. MicroRNAs Cause Accelerated Decay of Short-Tailed Target mRNAs

   Timothy J. Eisen, Stephen W. Eichhorn, Alexander O. Subtelny, D. Bartel

   2019bioRxiv41 citations Open access

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5. The interplay between translational efficiency, poly(A) tails, microRNAs, and neuronal activation

   Timothy J. Eisen, J. Li, D. Bartel

   2022RNA: A publication of the RNA Society17 citations Open access

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6. Affinity Inequality among Serum Antibodies That Originate in Lymphoid Germinal Centers

   Myungsun Kang, Timothy J. Eisen, E. Eisen, A. Chakraborty +1 more

   2015PLoS ONE12 citations Open access

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7. Stimulation of the catalytic activity of the tyrosine kinase Btk by the adaptor protein Grb2

   Laura M. Nocka, Timothy J. Eisen, A. Iavarone, J. Groves +1 more

   2022bioRxiv11 citations Open access

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8. Conditional requirement for dimerization of the membrane-binding module for BTK signaling in lymphocyte cell lines

   Timothy J. Eisen, Sam Ghaffari-Kashani, Chien-Lun Hung, Jay T. Groves +2 more

   2025Science Signaling9 citations

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9. A subset of platinum-containing chemotherapeutic agents kill cells by inducing ribosome biogenesis stress rather than by engaging a DNA damage response

   P. M. Bruno, Yunpeng Liu, Ga-Young Park, J. Murai +6 more

   20178 citations

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10. Persistent Activation of mRNA Translation by Transient Hsp90 Inhibition

    P. Tsvetkov, Timothy J. Eisen, Sven U. Heinrich, Zarina Brune +5 more

    2020Cell Reports3 citations Open access

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11. Persistent Activation of mRNA Translation by Transient Hsp90 Inhibition.

    P. Tsvetkov, Timothy J. Eisen, Sven U. Heinrich, Zarina Brune +5 more

    2020Cell Reports2 citations Open access

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12. Asymmetric dimerization and allosteric control in the epidermal growth factor receptor.

    Yong-Jian Huang, Timothy J. Eisen, Arathi Nair, Serena Muratcioglu +1 more

    2026Philosophical transactions of the Royal Society of London. Series B, Biological sciences1 citations Open access

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13. LAT condensation gates PLCγ1 activation via bimodal LAT phosphorylation

    He Ren, Hyun-Ro Lee, Y. Omar, Joseph B. DeGrandchamp +6 more

    2026bioRxiv1 citations Open access

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14. BPS2026 – Signaling protein nucleation and condensation in the T-cell signaling pathway

    Saehyun Choi, Timothy J. Eisen, Shumpei Morita, Jay T. Groves

    2026Biophysical Journal0 citations

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15. BPS2026 – Pre-assembly of a partial signaling unit primes T cell receptor signal transduction

    Timothy J. Eisen, Saehyun Choi, Jay T. Groves

    2026Biophysical Journal0 citations

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16. LAT condensation gates PLCγ1 activation via bimodal LAT phosphorylation

    He Ren, Hyun-Ro Lee, Y. Omar, Joseph B. DeGrandchamp +6 more

    2026Proceedings of the National Academy of Sciences of the United States of America0 citations Open access

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17. BTK Autoinhibition Analyzed by High-Throughput SH2 Domain Swaps

    Timothy J. Eisen, Sam Ghaffari-Kashani, Chien-Lun Hung, Jay T. Groves +1 more

    2025bioRxiv0 citations Open access

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18. BTK autoinhibition analyzed by high-throughput swaps of SH2 domains

    Timothy J. Eisen, Sam Ghaffari-Kashani, Chien-Lun Hung, J. T. Groves +1 more

    2025Proceedings of the National Academy of Sciences of the United States of America0 citations Open access

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19. T cell costimulatory and inhibitory signals differentially modulate LAT condensate nucleation propensity after TCR ligation

    Saehyun Choi, Sungi Kim, Jessica Tijham, Timothy J. Eisen +3 more

    2025bioRxiv0 citations Open access

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20. Conditional Requirement for Dimerization of the Membrane-Binding Module of BTK

    Timothy J. Eisen, Sam Ghaffari-Kashani, J. T. Groves, Arthur Weiss +1 more

    2024bioRxiv0 citations Open access

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21. Drug discovery targeting SARS-CoV-2 membrane fusion

    Kailu Yang, Chu-Chu Wang, Alex J. B. Kreutzberger, Ravi Ojha +11 more

    2023Biophysical Journal0 citations Open access

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22. Transient Hsp90 suppression promotes a heritable change in protein translation

    P. Tsvetkov, Zarina Brune, Timothy J. Eisen, Sven U. Heinrich +5 more

    2018bioRxiv0 citations Open access

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23. MIT Open Access Articles Affinity Inequality among Serum Antibodies That Originate in Lymphoid Germinal Centers

    Myungsun Kang, Timothy J. Eisen, Ellen A. Eisen, Arup K. Chakraborty +1 more

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