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E. Mounetou · SciRah

Researcher profile · Semantic Scholar

E. Mounetou

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E. Mounetou — researcher profile on SciRah

h-index: 11
Works: 31
Citations: 441

Most-cited papers

Microtubule disruption induced in vivo by alkylation of beta-tubulin by 1-aryl-3-(2-chloroethyl)ureas, a novel class of soft alkylating agents.
Jean Legault, J. Gaulin, E. Mounetou, Sébastien Bolduc +3 more
2000Cancer Research62 citations
Semantic Scholar
Development and cytotoxic response of two proliferative MDA-MB-231 and non-proliferative SUM1315 three-dimensional cell culture models of triple-negative basal-like breast cancer cell lines
Clémence Dubois, R. Dufour, Pierre Daumar, C. Aubel +5 more
2017OncoTarget55 citations Open access
Semantic Scholar
Antiangiogenic and Antitumoral Activity of Phenyl-3-(2-Chloroethyl)Ureas
E. Petitclerc, Réna G. Deschesnes, Marie-France Côté, C. Marquis +7 more
2004Cancer Research52 citations
Semantic Scholar
Alkylation of β-Tubulin on Glu 198 by a Microtubule Disrupter
B. Bouchon, C. Chambon, E. Mounetou, J. Papon +4 more
2005Molecular Pharmacology38 citations
Semantic Scholar
A new generation of N-aryl-N'-(1-alkyl-2-chloroethyl)ureas as microtubule disrupters: synthesis, antiproliferative activity, and beta-tubulin alkylation kinetics.
E. Mounetou, J. Legault, J. Lacroix, René C-Gaudreault
2003Journal of Medicinal Chemistry36 citations
Semantic Scholar
Synthesis and in vitro evaluation of targeted tetracycline derivatives: effects on inhibition of matrix metalloproteinases.
Aurélien Vidal, M. Sabatini, G. Rolland-Valognes, P. Renard +2 more
2007Bioorganic & Medicinal Chemistry25 citations Open access
Semantic Scholar
Antineoplastic potency of arylchloroethylurea derivatives in murine colon carcinoma
E. Miot-Noirault, J. Legault, F. Cachin, E. Mounetou +4 more
2004Investigational new drugs22 citations
Semantic Scholar
N-(4-iodophenyl)-N′-(2-chloroethyl)urea as a microtubule disrupter: in vitro and in vivo profiling of antitumoral activity on CT-26 murine colon carcinoma cell line cultured and grafted to mice
Michèle Borel, Françoise Degoul, Y. Communal, E. Mounetou +4 more
2007British Journal of Cancer15 citations Open access
Semantic Scholar
A Simple and Efficient Synthesis of Methyl 3,4-Dihydro-2-methyl-2H-1,2-benzothiazine-3-carboxylate 1,1-Dioxide from Saccharin Sodium Salt
Aurélien Vidal, J. Madelmont, E. Mounetou
200615 citations
Semantic Scholar
Low-Dose and Long-Term Olaparib Treatment Sensitizes MDA-MB-231 and SUM1315 Triple-Negative Breast Cancers Spheroids to Fractioned Radiotherapy
Clémence Dubois, F. Martin, C. Hassel, F. Magnier +6 more
2019Journal of Clinical Medicine14 citations Open access
Semantic Scholar
The New Synthetic Serum-Free Medium OptiPASS Promotes High Proliferation and Drug Efficacy Prediction on Spheroids from MDA-MB-231 and SUM1315 Triple-Negative Breast Cancer Cell Lines
Clémence Dubois, Pierre Daumar, C. Aubel, J. Gauthier +4 more
2019Journal of Clinical Medicine11 citations Open access
Semantic Scholar
Enhancement by O6-benzyl-N-acetylguanosine derivatives of chloroethylnitrosourea antitumor action in chloroethylnitrosourea-resistant human malignant melanocytes.
C. Cussac, Maryse Rapp, E. Mounetou, J. Madelmont +6 more
1994Journal of Pharmacology and Experimental Therapeutics11 citations
Semantic Scholar
New quaternary ammonium oxicam derivatives: synthesis and in vitro antiosteoarthritis evaluation.
Aurélien Vidal, J. Chezal, E. Mounetou
2010European journal of medicinal chemistry10 citations
Semantic Scholar
N-4-iodophenyl-N′-2-chloroethylurea, a novel potential anticancer agent with colon-specific accumulation: radioiodination and comparative in vivo biodistribution profiles
E. Mounetou, E. Miot-Noirault, R. Gaudreault, J. Madelmont
2010Investigational new drugs9 citations
Semantic Scholar
LightSpot®-FL-1 Fluorescent Probe: An Innovative Tool for Cancer Drug Resistance Analysis by Direct Detection and Quantification of the P-glycoprotein (P-gp) on Monolayer Culture and Spheroid Triple Negative Breast Cancer Models
Antoine Goisnard, Pierre Daumar, Clémence Dubois, C. Aubel +7 more
2021Cancers8 citations Open access
Semantic Scholar
PEGylation enhances the tumor selectivity of melanoma-targeted conjugates.
M. André, S. Besse, J. Chezal, E. Mounetou
2015Organic and biomolecular chemistry7 citations
Semantic Scholar
A New O6-Alkylguanine-DNA Alkyltransferase Inhibitor Associated with a Nitrosourea (Cystemustine) Validates a Strategy of Melanoma-Targeted Therapy in Murine B16 and Human-Resistant M4Beu Melanoma Xenograft Models
M. Rapp, J. Maurizis, J. Papon, P. Labarre +5 more
2008Journal of Pharmacology and Experimental Therapeutics7 citations
Semantic Scholar
Alkylation of beta-tubulin on Glu 198 by a microtubule disrupter.
B. Bouchon, C. Chambon, E. Mounetou, J. Papon +4 more
2005Molecular Pharmacology7 citations
Semantic Scholar
Melanoma‐cell toxicity of cystemustine combined with O6-benzyl-N2-acetylguanosine
C. Buchdahl, C. Rolhion, A. Glasser, E. Débiton +3 more
1998Melanoma research7 citations
Semantic Scholar
Enhancement by O6-benzyl-N2-acetylguanosine of N'-[2-chloroethyl]-N-[2-(methylsulphonyl)ethyl]-N'-nitrosourea therapeutic index on nude mice bearing resistant human melanoma.
E. Débiton, C. Cussac-Buchdhal, E. Mounetou, M. Rapp +4 more
1997British Journal of Cancer7 citations Open access
Semantic Scholar
Spacer optimization of new conjugates for a melanoma-selective delivery approach.
M. André, S. Tarrit, M. Couret, M. Galmier +3 more
2013Organic and biomolecular chemistry5 citations
Semantic Scholar
Synthesis of three no-carrier-added O6-4-[125I] iodobenzylguanosine derivatives, new reagents for the assay of O6-alkylguanine-DNA alkyltransferase activity
E. Mounetou, Catherine Cussac, F. Mathieu, J. Maurizis +4 more
19955 citations
Semantic Scholar
Cytotoxicity Study of Gold Nanoparticles on the Basal-Like Triple-Negative HCC-1937 Breast Cancer Cell Line
C. Massard, Clémence Dubois, V. Raspal, Pierre Daumar +4 more
20184 citations Open access
Semantic Scholar
Optimization of Grignard ring-opening of α-brominated dioxolanes for the preparation of β-hydroxy-protected vinyl ethers by a three-step one-pot procedure
M. André, Boris Letribot, M. Bayle, E. Mounetou +1 more
20124 citations
Semantic Scholar
The New Serum-Free OptiPASS® Medium in Cold and Oxygen-Free Conditions: An Innovative Conservation Method for the Preservation of MDA-MB-231 Triple Negative Breast Cancer Spheroids
Antoine Goisnard, Clémence Dubois, Pierre Daumar, C. Aubel +6 more
2021Cancers2 citations Open access
Semantic Scholar
Synthesis of N-[2-(2-methylpropoxy)ethyl]-N-{2-[(4-methoxy) phenylmethylthio]phenyl}-1-pyrrolidineethanamine (E)-2-butenedioate (1:1) salt (CERM 12816): a potential anti-anginal drug
E. Mounetou, Claude Poisson, A. Monteil, J. Madelmont
19982 citations
Semantic Scholar
Disposition and metabolism of O6-alkylguanine-DNA alkyltransferase inhibitor in nude mice bearing human melanoma.
C. Cussac, E. Mounetou, Maryse Rapp, J. Madelmont +6 more
1994Drug Metabolism And Disposition2 citations
Semantic Scholar
Optimization of Grignard Ring-Opening of α-Brominated Dioxolanes for the Preparation of β-Hydroxy-Protected Vinyl Ethers by a Three-Step One-Pot Procedure.
M. André, Boris Letribot, M. Bayle, E. Mounetou +1 more
20130 citations
Semantic Scholar
Alkylation of (cid:1) -Tubulin on Glu 198 by a Microtubule Disrupter
B. Bouchon, C. Chambon, E. Mounetou, J. Papon +4 more
20050 citations
Semantic Scholar
Antimitotic Antitumor Agents: Synthesis, Structure—Activity Relationships, and Biological Characterization of N-Aryl-N′-(2-chloroethyl)ureas as New Selective Alkylating Agents.
E. Mounetou, J. Legault, J. Lacroix, R. C.-Gaudreault
20010 citations
Semantic Scholar
New derivatives of 1,1-dioxo-2H-1,2-benzothiazine-3-carboxamides, their process for the preparation and pharmaceutical compositions that contain the
J. Madelmont, I. Giraud, Aurélien Vidal, E. Mounetou +5 more
20000 citations
Semantic Scholar

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