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Hai-Chen Wang · SciRah

Researcher profile · Semantic Scholar

Hai-Chen Wang

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Hai-Chen Wang — researcher profile on SciRah

h-index: 32
Works: 76
Citations: 3,591

Most-cited papers

Increased miR‐124‐3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons
Shan Huang, Xin-Tong Ge, Jin-Wen Yu, Zhaoli Han +6 more
2018The FASEB Journal397 citations
Semantic Scholar
APOE Genotype and an ApoE-mimetic Peptide Modify the Systemic and Central Nervous System Inflammatory Response*
J. Lynch, Wen Tang, Hai-Chen Wang, M. Vitek +4 more
2003Journal of Biological Chemistry394 citations Open access
Semantic Scholar
Simvastatin Reduces Vasospasm After Aneurysmal Subarachnoid Hemorrhage: Results of a Pilot Randomized Clinical Trial
J. Lynch, Hai-Chen Wang, M. McGirt, J. Floyd +7 more
2005Stroke294 citations Open access
Semantic Scholar
Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury.
Hai-Chen Wang, J. Lynch, Pingping Song, Hyuk-Jun Yang +5 more
2007Experimental Neurology189 citations
Semantic Scholar
miR-21 improves the neurological outcome after traumatic brain injury in rats
Xin-Tong Ge, Ping Lei, Hai-Chen Wang, Anran Zhang +6 more
2014Scientific Reports166 citations Open access
Semantic Scholar
A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury.
J. Lynch, Hai-Chen Wang, B. Mace, Stephen B Leinenweber +5 more
2005Experimental Neurology129 citations
Semantic Scholar
The pathological role of NLRs and AIM2 inflammasome-mediated pyroptosis in damaged blood-brain barrier after traumatic brain injury.
Xin-Tong Ge, Wenzhu Li, Shan Huang, Zhen-Yu Yin +6 more
2018Brain Research126 citations
Semantic Scholar
Increases in miR-124-3p in Microglial Exosomes Confer Neuroprotective Effects by Targeting FIP200-Mediated Neuronal Autophagy Following Traumatic Brain Injury
Dai Li, Shan Huang, Zhen-Yu Yin, Jia-Lin Zhu +8 more
2019Neurochemical Research110 citations
Semantic Scholar
MiR-21 alleviates secondary blood-brain barrier damage after traumatic brain injury in rats.
Xin-Tong Ge, Zhaoli Han, Fang-Lian Chen, Hai-Chen Wang +4 more
2015Brain Research108 citations
Semantic Scholar
Levetiracetam is neuroprotective in murine models of closed head injury and subarachnoid hemorrhage
Hai-Chen Wang, Jun-Ling Gao, T. Lassiter, D. McDonagh +4 more
2006Neurocritical Care106 citations
Semantic Scholar
COG1410, a Novel Apolipoprotein E–Based Peptide, Improves Functional Recovery in a Murine Model of Traumatic Brain Injury
D. Laskowitz, S. McKenna, Pingping Song, Hai-Chen Wang +4 more
2007Journal of Neurotrauma103 citations
Semantic Scholar
Traumatic Brain Injury Exacerbates Neurodegenerative Pathology: Improvement with an Apolipoprotein E-Based Therapeutic
D. Laskowitz, Pingping Song, Hai-Chen Wang, B. Mace +3 more
2010Journal of Neurotrauma94 citations Open access
Semantic Scholar
A novel apoE-derived therapeutic reduces vasospasm and improves outcome in a murine model of subarachnoid hemorrhage
Jun-Ling Gao, Hai-Chen Wang, H. Sheng, J. Lynch +4 more
2006Neurocritical Care83 citations
Semantic Scholar
Tumor necrosis factor alpha antagonism improves neurological recovery in murine intracerebral hemorrhage
Beilei Lei, H. Dawson, Briana Roulhac-Wilson, Hai-Chen Wang +2 more
2013Journal of Neuroinflammation72 citations Open access
Semantic Scholar
Increased miR-21-3p in Injured Brain Microvascular Endothelial Cells after Traumatic Brain Injury Aggravates Blood–Brain Barrier Damage by Promoting Cellular Apoptosis and Inflammation through Targeting MAT2B
Xin-Tong Ge, Wenzhu Li, Shan Huang, Zhen-Yu Yin +7 more
2018Journal of Neurotrauma71 citations Open access
Semantic Scholar
Measurement of the mu decay spectrum with the ICARUS liquid argon TPC
S. Amoruso, M. Antonello, P. Aprili, F. Arneodo +101 more
200459 citations Open access
Semantic Scholar
PD-L1/PD-1 checkpoint pathway regulates hippocampal neuronal excitability and learning and memory behavior
Junli Zhao, S. Bang, K. Furutani, Aidan McGinnis +10 more
2023Neuron56 citations Open access
Semantic Scholar
Neuroprotective pentapeptide CN-105 is associated with reduced sterile inflammation and improved functional outcomes in a traumatic brain injury murine model
D. Laskowitz, Hai-Chen Wang, Toby Chen, David T. Lubkin +7 more
2017Scientific Reports54 citations Open access
Semantic Scholar
Brain Natriuretic Peptide Improves Long-Term Functional Recovery after Acute CNS Injury in Mice
M. James, Hai-Chen Wang, T. Venkatraman, Pingping Song +2 more
2010Journal of Neurotrauma54 citations Open access
Semantic Scholar
Dissociation between vasospasm and functional improvement in a murine model of subarachnoid hemorrhage.
R. Mesis, Hai-Chen Wang, F. Lombard, R. Yates +4 more
2006Neurosurgical Focus53 citations Open access
Semantic Scholar
Acoustofluidic separation enables early diagnosis of traumatic brain injury based on circulating exosomes
Zeyu Wang, Hai-Chen Wang, Ryan Becker, Joseph Rufo +6 more
2021Microsystems & Nanoengineering51 citations Open access
Semantic Scholar
Statins Improve Outcome in Murine Models of Intracranial Hemorrhage and Traumatic Brain Injury: A Translational Approach
F. Indraswari, Hai-Chen Wang, Beilei Lei, M. James +4 more
2012Journal of Neurotrauma50 citations
Semantic Scholar
Apolipoprotein E mimetic peptide, CN‐105, improves outcomes in ischemic stroke
Tian-Ming Tu, Brad J. Kolls, E. Soderblom, Viviana Cantillana +5 more
2017Annals of Clinical and Translational Neurology45 citations Open access
Semantic Scholar
Association of Glomerular Filtration Rate With Outcomes of Acute Stroke in Type 2 Diabetic Patients: Results From the China National Stroke Registry
Yang Luo, Xianwei Wang, Yi-Long Wang, Chun-Xue Wang +7 more
2013Diabetes Care43 citations Open access
Semantic Scholar
Neuroprotective pentapeptide CN-105 improves functional and histological outcomes in a murine model of intracerebral hemorrhage
Beilei Lei, M. James, Ji Liu, Guan-En Zhou +6 more
2016Scientific Reports41 citations Open access
Semantic Scholar
The apoE-mimetic Peptide, COG1410, Improves Functional Recovery in a Murine Model of Intracerebral Hemorrhage
D. Laskowitz, Beilei Lei, H. Dawson, Hai-Chen Wang +4 more
2012Neurocritical Care41 citations
Semantic Scholar
A No-Laminectomy Spinal Cord Compression Injury Model in Mice
H. Sheng, Hai-Chen Wang, H. Homi, I. Spasojević +3 more
2004Journal of Neurotrauma40 citations
Semantic Scholar
ApoE mimetic improves pathology and memory in a model of Alzheimer's disease.
K. Krishnamurthy, Viviana Cantillana, Hai-Chen Wang, P. Sullivan +5 more
2020Brain Research36 citations
Semantic Scholar
Intrastriatal injection of autologous blood or clostridial collagenase as murine models of intracerebral hemorrhage.
Beilei Lei, H. Sheng, Hai-Chen Wang, C. Lascola +3 more
2014Journal of Visualized Experiments36 citations Open access
Semantic Scholar
Energy Reconstruction of Electromagnetic Showers from π0 Decays with the ICARUS T600 Liquid Argon TPC
A. Ankowski, M. Antonello, P. Aprili, F. Arneodo +87 more
200836 citations
Semantic Scholar
ApolipoproteinE mimetic peptides improve outcome after focal ischemia.
Hai-Chen Wang, Lauren G. Anderson, C. Lascola, M. James +5 more
2013Experimental Neurology35 citations
Semantic Scholar
Targeting the SUMO pathway for neuroprotection in brain ischaemia
Wei Yang, H. Sheng, Hai-Chen Wang
2016Stroke and vascular neurology34 citations Open access
Semantic Scholar
TT-301 Inhibits Microglial Activation and Improves Outcome after Central Nervous System Injury in Adult Mice
M. James, Hai-Chen Wang, Viviana Cantillana, Beilei Lei +4 more
2012Anesthesiology29 citations Open access
Semantic Scholar
Progesterone Improves Neurobehavioral Outcome in Models of Intracerebral Hemorrhage
Beilei Lei, Hai-Chen Wang, Seongtae Jeong, Justin T. Hsieh +5 more
2015Neuroendocrinology27 citations
Semantic Scholar
Lacosamide Improves Outcome in a Murine Model of Traumatic Brain Injury
Bo Wang, H. Dawson, Hai-Chen Wang, D. Kernagis +3 more
2013Neurocritical Care26 citations
Semantic Scholar
Apolipoprotein E mimetic peptide CN-105 improves outcome in a murine model of SAH
Ji Liu, Guan-En Zhou, Brad J. Kolls, Yan-Li Tan +3 more
2018Stroke and vascular neurology25 citations Open access
Semantic Scholar
Effect of Acute Physical Interventions on Pathophysiology and Recovery After Spinal Cord Injury: A Comprehensive Review of the Literature
Nicholle E. Lewis, Troy Q. Tabarestani, Brianna R. Cellini, Nina Zhang +5 more
2022Neurospine24 citations Open access
Semantic Scholar
pH-Sensitive NMDA Inhibitors Improve Outcome in a Murine Model of SAH
Hai-Chen Wang, M. James, T. Venkatraman, L. Wilson +4 more
2014Neurocritical Care24 citations
Semantic Scholar
Rapidly regulating platelet activity in vivo with an antidote controlled platelet inhibitor.
Shahid M. Nimjee, J. Lohrmann, Hai-Chen Wang, David J. Snyder +4 more
2012Molecular Therapy23 citations Open access
Semantic Scholar
Apolipoprotein E modifies the CNS response to injury via a histamine-mediated pathway
B. Mace, Hai-Chen Wang, J. Lynch, J. Moss +5 more
2007Neurological Research21 citations
Semantic Scholar
Intravenous immunoglobulin G improves neurobehavioral and histological outcomes after traumatic brain injury in mice.
Seongtae Jeong, Beilei Lei, Hai-Chen Wang, H. Dawson +1 more
2014Journal of Neuroimmunology20 citations
Semantic Scholar
Mn Porphyrins as Novel Molecular Magnetic Resonance Imaging Contrast Agents
V. Mouraviev, T. Venkatraman, A. Tovmasyan, M. Kimura +7 more
2012Journal of endourology20 citations Open access
Semantic Scholar
Neuroprotective pentapeptide, CN-105, improves outcomes in translational models of intracerebral hemorrhage
Hai-Chen Wang, Timothy D. Faw, Yu-Feng Lin, Shan Huang +5 more
2020bioRxiv17 citations Open access
Semantic Scholar
Surgical Considerations to Improve Recovery in Acute Spinal Cord Injury
Troy Q. Tabarestani, Nicholle E. Lewis, Margot Kelly-Hedrick, Nina Zhang +7 more
2022Neurospine16 citations Open access
Semantic Scholar
Argon Inhalation for 24 h After Closed-Head Injury Does not Improve Recovery, Neuroinflammation, or Neurologic Outcome in Mice
J. Creed, Viviana Cantillana-Riquelme, Baihui Yan, Shuang Ma +5 more
2020Neurocritical Care16 citations
Semantic Scholar
Therapeutic Development of Apolipoprotein E Mimetics for Acute Brain Injury: Augmenting Endogenous Responses to Reduce Secondary Injury
M. James, Jordan M. Komisarow, Hai-Chen Wang, D. Laskowitz
2020Neurotherapeutics16 citations Open access
Semantic Scholar
Poor performance of stroke prognostication using Age and National Institutes of Health Stroke Scale-100 to predict 3- and 12-month outcomes of ischemic stroke in China National Stroke Registry.
Yue-Song Pan, J. Jing, Runhua Zhang, Xing-Quan Zhao +6 more
2014Journal of Stroke & Cerebrovascular Diseases14 citations
Semantic Scholar
Tumor necrosis factor alpha antagonism improves neurological recovery in murine intracerebral hemorrhage
Beilei Lei, H. Dawson, Briana Roulhac-Wilson, Hai-Chen Wang +2 more
2013Journal of Neuroinflammation11 citations Open access
Semantic Scholar
A Reversible Aptamer Improves Outcome and Safety in Murine Models of Stroke and Hemorrhage
Charlene M. Blake, Hai-Chen Wang, D. Laskowitz, B. Sullenger
2011Oligonucleotides11 citations Open access
Semantic Scholar
Effects of a manganese (III) porphyrin catalytic antioxidant in a mouse closed head injury model.
Stephen B Leinenweber, H. Sheng, J. Lynch, Hai-Chen Wang +5 more
2006European Journal of Pharmacology11 citations
Semantic Scholar

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