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H. Wachi · SciRah

Researcher profile · Semantic Scholar

H. Wachi

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H. Wachi — researcher profile on SciRah

h-index: 29
Works: 94
Citations: 2,253

Most-cited papers

Direct evidence for the involvement of brain‐derived neurotrophic factor in the development of a neuropathic pain‐like state in mice
Y. Yajima, M. Narita, A. Usui, C. Kaneko +7 more
2005Journal of Neurochemistry165 citations Open access
Semantic Scholar
New insights into the pathogenesis of autosomal dominant cutis laxa with report of five ELN mutations
B. Callewaert, M. Renard, V. Hucthagowder, B. Albrecht +11 more
2011Human Mutation128 citations Open access
Semantic Scholar
Domains in Tropoelastin That Mediate Elastin Depositionin Vitro and in Vivo *
B. Kozel, H. Wachi, E. Davis, R. Mecham
2003Journal of Biological Chemistry128 citations Open access
Semantic Scholar
Role of δ‐opioid receptor function in neurogenesis and neuroprotection
M. Narita, Naoko Kuzumaki, M. Miyatake, Fumiaki Sato +3 more
2006107 citations
Semantic Scholar
Chronic pain‐induced emotional dysfunction is associated with astrogliosis due to cortical δ‐opioid receptor dysfunction
M. Narita, Naoko Kuzumaki, Michiko Narita, C. Kaneko +10 more
2006Journal of Neurochemistry98 citations
Semantic Scholar
Distinct steps of cross-linking, self-association, and maturation of tropoelastin are necessary for elastic fiber formation.
Fumiaki Sato, H. Wachi, Marie Ishida, R. Nonaka +4 more
2007Journal of Molecular Biology79 citations
Semantic Scholar
Modulation by elastin peptide VGVAPG of cell proliferation and elastin expression in human skin fibroblasts
Shingo Tajima, H. Wachi, Y. Uemura, K. Okamoto
1997Archives of Dermatological Research70 citations
Semantic Scholar
Characterization of an in vitro model of elastic fiber assembly.
Bruce W. Robb, H. Wachi, Theresa Schaub, R. Mecham +1 more
1999Molecular Biology of the Cell67 citations Open access
Semantic Scholar
Accumulation of elafin in actinic elastosis of sun-damaged skin: elafin binds to elastin and prevents elastolytic degradation.
J. Muto, K. Kuroda, H. Wachi, S. Hirose +1 more
2007Journal of Investigative Dermatology63 citations Open access
Semantic Scholar
Increase in elastin gene expression and protein synthesis in arterial smooth muscle cells derived from patients with Moyamoya disease.
M. Yamamoto, M. Aoyagi, S. Tajima, H. Wachi +3 more
1997Stroke63 citations
Semantic Scholar
An Open Reading Frame Element Mediates Posttranscriptional Regulation of Tropoelastin and Responsiveness to Transforming Growth Factor β1
Man-Cong Zhang, R. Pierce, H. Wachi, R. Mecham +1 more
1999Molecular and Cellular Biology59 citations Open access
Semantic Scholar
Stimulation of cell proliferation and autoregulation of elastin expression by elastin peptide VPGVG in cultured chick vascular smooth muscle cells
H. Wachi, Yoshiyuki Seyama, S. Yamashita, H. Suganami +4 more
1995FEBS Letters56 citations Open access
Semantic Scholar
Role of delta-opioid receptor function in neurogenesis and neuroprotection.
M. Narita, Naoko Kuzumaki, M. Miyatake, Fumiaki Sato +3 more
2006Journal of Neurochemistry55 citations
Semantic Scholar
Age- and Gender-Related Changes in Ligament Components
T. Osakabe, Mikio Hayashi, K. Hasegawa, T. Okuaki +4 more
2001Annals of Clinical Biochemistry51 citations Open access
Semantic Scholar
N(ɛ)-(carboxymethyl)lysine modification of elastin alters its biological properties: implications for the accumulation of abnormal elastic fibers in actinic elastosis.
E. Yoshinaga, A. Kawada, K. Ono, E. Fujimoto +4 more
2012Journal of Investigative Dermatology50 citations Open access
Semantic Scholar
Trichostatin A, an HDAC class I/II inhibitor, promotes Pi-induced vascular calcification via up-regulation of the expression of alkaline phosphatase.
T. Azechi, D. Kanehira, Takashi Kobayashi, R. Sudo +3 more
2013Journal of atherosclerosis and thrombosis49 citations Open access
Semantic Scholar
7‐Ketocholesterol‐induced lysosomal dysfunction exacerbates vascular smooth muscle cell calcification via oxidative stress
R. Sudo, Fumiaki Sato, T. Azechi, H. Wachi
2015Genes to Cells47 citations Open access
Semantic Scholar
MiR‐29‐mediated elastin down‐regulation contributes to inorganic phosphorus‐induced osteoblastic differentiation in vascular smooth muscle cells
R. Sudo, Fumiaki Sato, T. Azechi, H. Wachi
2015Genes to Cells43 citations Open access
Semantic Scholar
Vascular NAD(P)H oxidase mediates endothelial dysfunction in basilar arteries from Otsuka Long-Evans Tokushima Fatty (OLETF) rats.
T. Matsumoto, Tsuneo Kobayashi, H. Wachi, Y. Seyama +1 more
2007Atherosclerosis42 citations
Semantic Scholar
Atherosclerosis and matrix dystrophy.
Y. Seyama, H. Wachi
2004Journal of atherosclerosis and thrombosis42 citations Open access
Semantic Scholar
Minoxidil stimulates elastin expression in aortic smooth muscle cells.
A. Hayashi, T. Suzuki, H. Wachi, Shingo Tajima +3 more
1994Archives of Biochemistry and Biophysics41 citations
Semantic Scholar
5-aza-2'-Deoxycytidine, a DNA methyltransferase inhibitor, facilitates the inorganic phosphorus-induced mineralization of vascular smooth muscle cells.
T. Azechi, Fumiaki Sato, R. Sudo, H. Wachi
2014Journal of atherosclerosis and thrombosis39 citations Open access
Semantic Scholar
Elastin synthesis is inhibited by angiotensin II but not by platelet-derived growth factor in arterial smooth muscle cells.
I. Tokimitsu, Hidehito Kato, H. Wachi, S. Tajima
1994Biochimica et Biophysica Acta39 citations
Semantic Scholar
Development of a new in vitro model of elastic fiber assembly in human pigmented epithelial cells.
H. Wachi, Fumiaki Sato, Hayato Murata, Junji Nakazawa +2 more
2005Clinical Biochemistry34 citations
Semantic Scholar
Characterization of the molecular interaction between tropoelastin and DANCE/fibulin-5.
H. Wachi, R. Nonaka, Fumiaki Sato, Kayoko Shibata-Sato +7 more
2008Journal of Biochemistry (Tokyo)33 citations
Semantic Scholar
Treatment with Vitamin K2 Combined with Bisphosphonates Synergistically Inhibits Calcification in Cultured Smooth Muscle Cells
E. Saito, H. Wachi, Fumiaki Sato, Hideki Sugitani +1 more
200731 citations Open access
Semantic Scholar
Tropoelastin inhibits vascular calcification via 67-kDa elastin binding protein in cultured bovine aortic smooth muscle cells.
H. Wachi, Hideki Sugitani, Hayato Murata, Junji Nakazawa +2 more
2004Journal of atherosclerosis and thrombosis30 citations Open access
Semantic Scholar
Domains 16 and 17 of tropoelastin in elastic fibre formation.
H. Wachi, Fumiaki Sato, Junji Nakazawa, R. Nonaka +9 more
2007Biochemical Journal29 citations Open access
Semantic Scholar
Upregulation of rhoA mRNA in bronchial smooth muscle of antigen-induced airway hyperresponsive rats.
Y. Chiba, Hiroyasu Sakai, H. Wachi, Hideki Sugitani +2 more
2003Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi29 citations Open access
Semantic Scholar
Effects of Bidens pilosa L. var. radiata Scherff on experimental gastric lesion
M. Horiuchi, H. Wachi, Y. Seyama
2010Journal of Natural Medicines25 citations
Semantic Scholar
Cell cycle-dependent regulation of elastin gene in cultured chick vascular smooth-muscle cells.
H. Wachi, Yoshiyuki Seyama, S. Yamashita, Shingo Tajima
1995Biochemical Journal25 citations Open access
Semantic Scholar
Lysyl Oxidase Enhances the Deposition of Tropoelastin through the Catalysis of Tropoelastin Molecules on the Cell Surface.
Fumiaki Sato, Ryo Seino-Sudo, M. Okada, Hiroyasu Sakai +2 more
2017Biological and Pharmaceutical Bulletin24 citations Open access
Semantic Scholar
7-ketocholesterol, a major oxysterol, promotes pi-induced vascular calcification in cultured smooth muscle cells.
E. Saito, H. Wachi, Fumiaki Sato, Y. Seyama
2008Journal of atherosclerosis and thrombosis24 citations Open access
Semantic Scholar
Asnovolins A-G, Spiromeroterpenoids Isolated from the Fungus Aspergillus novofumigatus, and Suppression of Fibronectin Expression by Asnovolin E.
Kazuki Ishikawa, Fumiaki Sato, Takeshi Itabashi, H. Wachi +5 more
2016Journal of Natural Products23 citations
Semantic Scholar
Galectin‐7 and actin are components of amyloid deposit of localized cutaneous amyloidosis
Y. Miura, S. Harumiya, K. Ono, E. Fujimoto +5 more
2013Experimental Dermatology22 citations
Semantic Scholar
Role of Elastic Fibers on Cardiovascular Disease
H. Wachi
201122 citations Open access
Semantic Scholar
DANCE/fibulin-5 promotes elastic fiber formation in a tropoelastin isoform-dependent manner.
R. Nonaka, S. Onoue, H. Wachi, Fumiaki Sato +3 more
2009Clinical Biochemistry22 citations
Semantic Scholar
Characterization of an in vitro model of calcification in retinal pigmented epithelial cells.
Hideki Sugitani, H. Wachi, Hayato Murata, Fumiaki Sato +2 more
2003Journal of atherosclerosis and thrombosis22 citations Open access
Semantic Scholar
Vulcanization of a Fluoroelastomer Derived from Tetrafluoroethylene and Propylene
G. Kojima, H. Wachi
197821 citations
Semantic Scholar
Advanced glycation end product-modified beta2-microglobulin is a component of amyloid fibrils of primary localized cutaneous nodular amyloidosis.
N. Fujimoto, M. Yajima, Y. Ohnishi, S. Tajima +6 more
2002Journal of Investigative Dermatology20 citations Open access
Semantic Scholar
Accelerated calcification represses the expression of elastic fiber components and lysyl oxidase in cultured bovine aortic smooth muscle cells.
Hideki Sugitani, H. Wachi, R. Mecham, Y. Seyama
2002Journal of atherosclerosis and thrombosis20 citations Open access
Semantic Scholar
Domain 36 of tropoelastin in elastic fiber formation.
R. Nonaka, Fumiaki Sato, H. Wachi
2014Biological and Pharmaceutical Bulletin17 citations Open access
Semantic Scholar
Treatment with vitamin k(2) combined with bisphosphonates synergistically inhibits calcification in cultured smooth muscle cells.
E. Saito, H. Wachi, Fumiaki Sato, Hideki Sugitani +1 more
2007Journal of atherosclerosis and thrombosis17 citations
Semantic Scholar
IsoChichibabin desmosine-13C3,15N1 synthesis and quantitative LC-MS/MS analysis of desmosine and isodesmosine in human skin.
M. Hirose, Toyoaki Kobayashi, Nao Tanaka, Ayame Mikagi +3 more
2021Bioorganic & Medicinal Chemistry16 citations Open access
Semantic Scholar
The cytotoxic and antifungal activities of two new sesquiterpenes, malfilanol A and B, derived from Malbranchea filamentosa
Daigo Wakana, T. Hosoe, H. Wachi, Takeshi Itabashi +3 more
2009Journal of antibiotics (Tokyo. 1968)15 citations
Semantic Scholar
The characteristics of elastic fiber assembled with recombinant tropoelastin isoform.
Fumiaki Sato, H. Wachi, B. Starcher, Hayato Murata +3 more
2006Clinical Biochemistry15 citations
Semantic Scholar
[Assessment of antioxidant activity of natural compound by water- and lipid-soluble antioxidant factor].
E. Usami, G. Kusano, Takanori Katayose, H. Wachi +1 more
2004Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan15 citations Open access
Semantic Scholar
Preliminary Experiments of Grafting of Maleic Anhydride onto Polypropylene in Molten State by Use of Screw Extruder.
M. Fujiyama, T. Wakino, H. Wachi, Kazuo Tani
199215 citations Open access
Semantic Scholar
Matrix metalloproteinase 9 expression is coordinately modulated by the KRE-M9 and 12-O-tetradecanoyl-phorbol-13-acetate responsive elements.
Takashi Kobayashi, J. Kishimoto, S. Hattori, H. Wachi +2 more
2004Journal of Investigative Dermatology14 citations Open access
Semantic Scholar
Removal of Unreacted Maleic Anhydride by Heat Treatment in Grafting of Maleic Anhydride onto Polypropylene in Molten State by Use of Screw Extruder.
M. Fujiyama, T. Wakino, H. Wachi, Kazuo Tani
199211 citations Open access
Semantic Scholar

Frequent co-authors

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Fumiaki Sato×21
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Fumiaki Sato — researcher profile on SciRah
Y. Seyama×21
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Y. Seyama — researcher profile on SciRah
S. Tajima×7
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S. Tajima — researcher profile on SciRah
R. Mecham×6
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R. Mecham — researcher profile on SciRah

Hideki Sugitani

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Hideki Sugitani — researcher profile on SciRah

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Z. Urban — researcher profile on SciRah

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R. Nonaka — researcher profile on SciRah

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B. Starcher — researcher profile on SciRah

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M. Miyatake — researcher profile on SciRah

Yoshiyuki Seyama×4

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Yoshiyuki Seyama — researcher profile on SciRah

Tsutomu Suzuki×4

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Tsutomu Suzuki — researcher profile on SciRah

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T. Azechi — researcher profile on SciRah