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M. Alahuhta · SciRah

Researcher profile · Semantic Scholar

M. Alahuhta

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M. Alahuhta — researcher profile on SciRah

h-index: 18
Works: 59
Citations: 1,167

Most-cited papers

Revealing Nature’s Cellulase Diversity: The Digestion Mechanism of Caldicellulosiruptor bescii CelA
R. Brunecky, M. Alahuhta, Qi Xu, B. Donohoe +8 more
2013Science279 citations
Semantic Scholar
Structural, Mutagenic and In Silico studies of Xyloglucan Fucosylation in Arabidopsis thaliana Suggest a Water-Mediated Mechanism
B. Urbanowicz, Vivek S. Bharadwaj, M. Alahuhta, M. Pena +9 more
2017The Plant Journal57 citations Open access
Semantic Scholar
Engineering towards a complete heterologous cellulase secretome in Yarrowia lipolytica reveals its potential for consolidated bioprocessing
Hui Wei, Wei Wang, M. Alahuhta, Todd A. Vander Wall +5 more
2014Biotechnology for Biofuels55 citations Open access
Semantic Scholar
Molecular Mechanism of Polysaccharide Acetylation by the Arabidopsis Xylan O-acetyltransferase XOAT1
V. Lunin, Hsin-Tzu Wang, Vivek S. Bharadwaj, M. Alahuhta +9 more
2020The Plant Cell50 citations Open access
Semantic Scholar
Structure of a Thermobifida fusca lytic polysaccharide monooxygenase and mutagenesis of key residues
Nathan Kruer-Zerhusen, M. Alahuhta, V. Lunin, M. Himmel +2 more
2017Biotechnology for Biofuels48 citations Open access
Semantic Scholar
Cel48A from Thermobifida fusca: Structure and site directed mutagenesis of key residues
Maxim Kostylev, M. Alahuhta, Mo Chen, R. Brunecky +4 more
2014Biotechnology and Bioengineering43 citations
Semantic Scholar
Atomic resolution crystallography of a complex of triosephosphate isomerase with a reaction‐intermediate analog: New insight in the proton transfer reaction mechanism
M. Alahuhta, R. Wierenga
2010Proteins: Structure, Function, and Bioinformatics43 citations
Semantic Scholar
Functional role of the conserved active site proline of triosephosphate isomerase.
Marco G. Casteleijn, M. Alahuhta, Katrin Groebel, I. El-Sayed +4 more
2007Biochemistry43 citations
Semantic Scholar
Sequence, Structure, and Evolution of Cellulases in Glycoside Hydrolase Family 48*
L. Sukharnikov, M. Alahuhta, R. Brunecky, Amit A. Upadhyay +3 more
2012Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Expression of an endoglucanase–cellobiohydrolase fusion protein in Saccharomyces cerevisiae, Yarrowia lipolytica, and Lipomyces starkeyi
Qi Xu, M. Alahuhta, Hui Wei, E. Knoshaug +5 more
2018Biotechnology for Biofuels37 citations Open access
Semantic Scholar
Heterologous Expression of Xylanase Enzymes in Lipogenic Yeast Yarrowia lipolytica
Wei Wang, Hui Wei, M. Alahuhta, Xiao-Wen Chen +4 more
2014PLoS ONE36 citations Open access
Semantic Scholar
The unique binding mode of cellulosomal CBM4 from Clostridium thermocellum cellobiohydrolase A.
M. Alahuhta, Qi Xu, Y. Bomble, R. Brunecky +4 more
2010Journal of Molecular Biology34 citations
Semantic Scholar
Discrete and Structurally Unique Proteins (Tāpirins) Mediate Attachment of Extremely Thermophilic Caldicellulosiruptor Species to Cellulose*
Sara E. Blumer-Schuette, M. Alahuhta, J. Conway, Laura L. Lee +6 more
2015Journal of Biological Chemistry31 citations Open access
Semantic Scholar
Target highlights in CASP14: analysis of models by structure providers
L. Alexander, R. Lepore, A. Kryshtafovych, A. Adamopoulos +34 more
2021Proteins: Structure, Function, and Bioinformatics29 citations Open access
Semantic Scholar
Structure of a fibronectin type III-like module from Clostridium thermocellum.
M. Alahuhta, Qi Xu, R. Brunecky, W. Adney +3 more
2010Acta Crystallographica. Section F : Structural Biology and Crystallization Communications24 citations Open access
Semantic Scholar
Crystal structure and biochemical characterization of Chlamydomonas FDX2 reveal two residues that, when mutated, partially confer FDX2 the redox potential and catalytic properties of FDX1
M. Boehm, M. Alahuhta, David W. Mulder, E. Peden +6 more
2015Photosynthesis Research22 citations Open access
Semantic Scholar
Structure-based protein engineering efforts with a monomeric TIM variant: the importance of a single point mutation for generating an active site with suitable binding properties.
M. Alahuhta, Mikko Salin, Marco G. Casteleijn, C. Kemmer +4 more
2008Protein engineering, design & selection : PEDS20 citations
Semantic Scholar
Structure and function of the Clostridium thermocellum cellobiohydrolase A X1-module repeat: enhancement through stabilization of the CbhA complex.
R. Brunecky, M. Alahuhta, Y. Bomble, Qi Xu +4 more
2012Acta Crystallographica Section D: Biological Crystallography19 citations
Semantic Scholar
A 1.5 Å resolution X-ray structure of the catalytic module of Caldicellulosiruptor bescii family 3 pectate lyase.
M. Alahuhta, Puja Chandrayan, I. Kataeva, M. Adams +2 more
2011Acta Crystallographica. Section F : Structural Biology and Crystallization Communications17 citations Open access
Semantic Scholar
Comparative Biochemical and Structural Analysis of Novel Cellulose Binding Proteins (Tāpirins) from Extremely Thermophilic Caldicellulosiruptor Species
Laura L. Lee, W. S. Hart, V. Lunin, M. Alahuhta +5 more
2018Applied and Environmental Microbiology16 citations Open access
Semantic Scholar
Expression and secretion of fungal endoglucanase II and chimeric cellobiohydrolase I in the oleaginous yeast Lipomyces starkeyi
Qi Xu, E. Knoshaug, Wei Wang, M. Alahuhta +7 more
2017Microbial Cell Factories16 citations Open access
Semantic Scholar
Protein crystallography of triosephosphate isomerases: functional and protein engineering studies
M. Alahuhta
200816 citations
Semantic Scholar
The catalytic mechanism and unique low pH optimum of Caldicellulosiruptor bescii family 3 pectate lyase.
M. Alahuhta, L. Taylor, R. Brunecky, D. Sammond +5 more
2015Acta Crystallographica Section D: Biological Crystallography15 citations Open access
Semantic Scholar
High resolution crystal structures of triosephosphate isomerase complexed with its suicide inhibitors: The conformational flexibility of the catalytic glutamate in its closed, liganded active site
R. Venkatesan, M. Alahuhta, P. Pihko, R. K. Wierenga
2011Protein Science14 citations Open access
Semantic Scholar
Structural studies show that the A178L mutation in the C-terminal hinge of the catalytic loop-6 of triosephosphate isomerase (TIM) induces a closed-like conformation in dimeric and monomeric TIM.
M. Alahuhta, Marco G. Casteleijn, P. Neubauer, R. Wierenga
2008Acta Crystallographica Section D: Biological Crystallography14 citations
Semantic Scholar
An iterative computational design approach to increase the thermal endurance of a mesophilic enzyme
D. Sammond, Noah Kastelowitz, B. Donohoe, M. Alahuhta +8 more
2018Biotechnology for Biofuels13 citations Open access
Semantic Scholar
Natural diversity of glycoside hydrolase family 48 exoglucanases: insights from structure
R. Brunecky, M. Alahuhta, D. Sammond, Qi Xu +6 more
2017Biotechnology for Biofuels13 citations Open access
Semantic Scholar
The structure and mode of action of Caldicellulosiruptor bescii family 3 pectate lyase in biomass deconstruction.
M. Alahuhta, R. Brunecky, Puja Chandrayan, I. Kataeva +3 more
2013Acta Crystallographica Section D: Biological Crystallography12 citations
Semantic Scholar
Phylogenetics-based identification and characterization of a superior 2,3-butanediol dehydrogenase for Zymomonas mobilis expression
V. Subramanian, V. Lunin, Samuel J. Farmer, M. Alahuhta +6 more
2020Biotechnology for Biofuels11 citations Open access
Semantic Scholar
Target highlights in CASP13: experimental target structures through the eyes of their authors
R. Lepore, A. Kryshtafovych, M. Alahuhta, H. A. Verasztó +31 more
2019Proteins: Structure, Function, and Bioinformatics11 citations Open access
Semantic Scholar
Strategies to reduce end‐product inhibition in family 48 glycoside hydrolases
Mo Chen, L. Bu, M. Alahuhta, R. Brunecky +6 more
2016Proteins: Structure, Function, and Bioinformatics11 citations
Semantic Scholar
Response to Comment on “Revealing Nature’s Cellulase Diversity: The Digestion Mechanism of Caldicellulosiruptor bescii CelA”
R. Brunecky, M. Alahuhta, Qi Xu, B. Donohoe +8 more
2014Science11 citations
Semantic Scholar
Structure of Acidothermus cellulolyticus family 74 glycoside hydrolase at 1.82 Å resolution.
M. Alahuhta, W. Adney, M. Himmel, V. Lunin
2013Acta Crystallographica. Section F : Structural Biology and Crystallization Communications11 citations Open access
Semantic Scholar
Long-Term Stability of Nicotinamide Cofactors in Common Aqueous Buffers: Implications for Cell-Free Biocatalysis
Kody D. Wolfe, M. Alahuhta, M. Himmel, Y. Bomble +2 more
2024Molecules10 citations Open access
Semantic Scholar
Characterization of the Biomass Degrading Enzyme GuxA from Acidothermus cellulolyticus
N. Hengge, S. Mallinson, P. Pason, V. Lunin +5 more
2022International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
Structure of CBM4 from Clostridium thermocellum cellulase K.
M. Alahuhta, Yong-Hua Luo, Shi-You Ding, M. Himmel +1 more
2011Acta Crystallographica. Section F : Structural Biology and Crystallization Communications9 citations Open access
Semantic Scholar
Cell-Free Systems Biology: Characterizing Central Metabolism of Clostridium thermocellum with a Three-Enzyme Cascade Reaction
S. Jilani, M. Alahuhta, Y. Bomble, Daniel G. Olson
2024ACS Synthetic Biology7 citations Open access
Semantic Scholar
Chimeric cellobiohydrolase I expression, activity, and biochemical properties in three oleaginous yeast
M. Alahuhta, Qi Xu, E. Knoshaug, Wei Wang +6 more
2021Biotechnology for Biofuels7 citations Open access
Semantic Scholar
Self-Assembling Metabolon Enables the Cell Free Conversion of Glycerol to 1,3-Propanediol
Qi Xu, M. Alahuhta, P. Hewitt, N. Sarai +5 more
2021Frontiers in Energy Research6 citations Open access
Semantic Scholar
Streamlining heterologous expression of top carbonic anhydrases in Escherichia coli: bioinformatic and experimental approaches
Hui Wei, V. Lunin, M. Alahuhta, M. Himmel +3 more
2024Microbial Cell Factories4 citations Open access
Semantic Scholar
Target highlights in CASP13: experimental target structures through the eyes of their authors. Proteins: Structure,
R. Lepore, A. Kryshtafovych, M. Alahuhta, H. A. Verasztó +39 more
20194 citations
Semantic Scholar
Issue Information ‐ Table of Content
J. Moult, Reinhard Albrecht, K. Chao, J. Greenfield +4 more
2021Proteins: Structure, Function, and Bioinformatics0 citations Open access
Semantic Scholar
Author response for "Target highlights in CASP14 : analysis of models by structure providers"
L. T. Alexander, R. Lepore, A. Kryshtafovych, A. Adamopoulos +34 more
20210 citations Open access
Semantic Scholar
Crystallography of Metabolic Enzymes.
M. Alahuhta, M. Himmel, Y. Bomble, V. Lunin
2020Methods in molecular biology0 citations
Semantic Scholar
Structure of the Xylan O-Acetyltransferase AtXOAT1 Reveals Molecular Insight into Polysaccharide Acetylation in Plants
V. Lunin, Hsin-Tzu Wang, Vivek S. Bharadwaj, M. Alahuhta +9 more
2020bioRxiv0 citations Open access
Semantic Scholar
Issue Information ‐ Table of Content
M. Alahuhta, H. A. Verasztó, Y. Bomble, J. Bufton +15 more
2019Proteins: Structure, Function, and Bioinformatics0 citations Open access
Semantic Scholar
Natural diversit y of gly coside hydrolase family 48 exoglucanases : insights fr om struc ture
R. Brunecky, M. Alahuhta, D. Sammond, Qi Xu +6 more
20170 citations
Semantic Scholar
Structur e of a T hermobifida fusc a lytic polysaccharide monooxygenase and mutagenesis of key r esidues
Nathan Kruer-Zerhusen, M. Alahuhta, V. Lunin, M. Himmel +2 more
20170 citations
Semantic Scholar
Prospect for Developing a Consolidated Bioprocessing (CBP) Strain Using Xylan as the Substrate: the Case Study of Yarrowia lipolytica
Wei Wang, Hui Wei, M. Alahuhta, Min Zhang +1 more
20160 citations
Semantic Scholar
Structural Studies of Biomass Degrading Enzyme Systems
V. Lunin, M. Alahuhta, G. Beckham, R. Brunecky +6 more
20140 citations Open access
Semantic Scholar

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