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Z. Ndhlovu · SciRah

Researcher profile · Semantic Scholar

Z. Ndhlovu

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Z. Ndhlovu — researcher profile on SciRah

h-index: 23
Works: 75
Citations: 3,266

Most-cited papers

Omicron extensively but incompletely escapes Pfizer BNT162b2 neutralization
S. Cele, Laurelle Jackson, D. Khoury, K. Khan +57 more
2021Nature1,087 citations Open access
Semantic Scholar
Magnitude and kinetics of CD8+ T cell activation during hyperacute HIV infection impacts viral set point
Z. Ndhlovu, Philomena Kamya, N. Mewalal, H. Kløverpris +17 more
2015Immunity267 citations Open access
Semantic Scholar
T cell receptor clonotypes modulate the protective effect of HLA class I alleles in HIV-1 infection
Hua-Biao Chen, Z. Ndhlovu, Dongfang Liu, Lindsay C. Porter +17 more
2012Nature Immunology248 citations Open access
Semantic Scholar
Cutting Edge: Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-Specific CD8 T Cells
Ben Youngblood, A. Noto, F. Porichis, Rama S. Akondy +13 more
2013Journal of Immunology156 citations Open access
Semantic Scholar
Innate Lymphoid Cells are Depleted Irreversibly During Acute HIV-1 Infection in the Absence of Viral Suppression
H. Kløverpris, S. Kazer, J. Mjösberg, Jenniffer M. Mabuka +22 more
2016Immunity146 citations Open access
Semantic Scholar
Integrated Single-Cell Analysis of Multicellular Immune Dynamics during Hyper-Acute HIV-1 Infection
S. Kazer, T. Aicher, Daniel M. Muema, Shaina L. Carroll +17 more
2020Nature Medicine138 citations Open access
Semantic Scholar
Major Scientific Hurdles in HIV Vaccine Development: Historical Perspective and Future Directions
Ng, Tiza Uni, Caroline Chasara, Z. Ndhlovu
2020Frontiers in Immunology124 citations Open access
Semantic Scholar
Elite Controllers with Low to Absent Effector CD8+ T Cell Responses Maintain Highly Functional, Broadly Directed Central Memory Responses
Z. Ndhlovu, J. Proudfoot, K. Cesa, D. Alvino +6 more
2012Journal of Virology99 citations Open access
Semantic Scholar
Guidelines for T cell nomenclature.
D. Masopust, A. Awasthi, Rémy Bosselut, D. G. Brooks +56 more
2025Nature reviews. Immunology98 citations Open access
Semantic Scholar
Escape from recognition of SARS-CoV-2 Beta variant spike epitopes but overall preservation of T cell immunity
C. Riou, R. Keeton, T. Moyo-Gwete, T. Hermanus +48 more
2021Science Translational Medicine92 citations Open access
Semantic Scholar
Detection and treatment of Fiebig stage I HIV-1 infection in young at-risk women in South Africa: a prospective cohort study
Krista L. Dong, A. Moodley, D. Kwon, M. Ghebremichael +9 more
2017The Lancet HIV91 citations Open access
Semantic Scholar
Omicron infection enhances Delta antibody immunity in vaccinated persons
K. Khan, Farina Karim, S. Cele, K. Reedoy +52 more
2022Nature79 citations Open access
Semantic Scholar
A high-dimensional immune monitoring model of HIV-1-specific CD8 T cell responses accurately identifies subjects achieving spontaneous viral control
Z. Ndhlovu, L. Chibnik, J. Proudfoot, Seanna M. Vine +14 more
2012Retrovirology73 citations Open access
Semantic Scholar
Augmentation of HIV-specific T cell function by immediate treatment of hyperacute HIV-1 infection
Z. Ndhlovu, S. Kazer, Thandeka Nkosi, Funsho J. Ogunshola +10 more
2019Science Translational Medicine70 citations Open access
Semantic Scholar
Association between the cytokine storm, immune cell dynamics, and viral replicative capacity in hyperacute HIV infection
Daniel M. Muema, N. Akilimali, O. Ndumnego, Sipho S. Rasehlo +11 more
2020BMC Medicine64 citations Open access
Semantic Scholar
Broad and persistent Gag-specific CD8+ T-cell responses are associated with viral control but rarely drive viral escape during primary HIV-1 infection
M. Radebe, K. Gounder, M. Mokgoro, Z. Ndhlovu +6 more
2015AIDS (London)56 citations Open access
Semantic Scholar
Frequencies of Circulating Th1-Biased T Follicular Helper Cells in Acute HIV-1 Infection Correlate with the Development of HIV-Specific Antibody Responses and Lower Set Point Viral Load
O. Baiyegunhi, B. Ndlovu, Funsho J. Ogunshola, N. Ismail +3 more
2018Journal of Virology50 citations Open access
Semantic Scholar
The Breadth of Expandable Memory CD8+ T Cells Inversely Correlates with Residual Viral Loads in HIV Elite Controllers
Z. Ndhlovu, Eleni Stampouloglou, K. Cesa, Orestes Mavrothalassitis +8 more
2015Journal of Virology45 citations Open access
Semantic Scholar
CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles
Catherine K. Koofhethile, Z. Ndhlovu, Christina F Thobakgale-Tshabalala, J. Prado +8 more
2016Journal of Virology32 citations Open access
Semantic Scholar
Mosaic HIV-1 Gag antigens can be Processed and Presented to human HIV-specific CD8+ T cells
Z. Ndhlovu, A. Piechocka-Trocha, Seanna M. Vine, A. McMullen +5 more
2011Journal of Immunology31 citations Open access
Semantic Scholar
Unsuppressed HIV infection impairs T cell responses to SARS-CoV-2 infection and abrogates T cell cross-recognition
Z. Ndhlovu, Thandeka Nkosi, Anele Mbatha, Mza Nsimbi +9 more
2022medRxiv24 citations Open access
Semantic Scholar
CD8 lymphocytes mitigate HIV-1 persistence in lymph node follicular helper T cells during hyperacute-treated infection
O. Baiyegunhi, J. Mann, T. Khaba, Thandeka Nkosi +11 more
2022Nature Communications23 citations Open access
Semantic Scholar
HIV Controllers Exhibit Enhanced Frequencies of Major Histocompatibility Complex Class II Tetramer+ Gag-Specific CD4+ T Cells in Chronic Clade C HIV-1 Infection
F. Laher, S. Ranasinghe, F. Porichis, N. Mewalal +8 more
2017Journal of Virology23 citations Open access
Semantic Scholar
Prolonged Exposure to HIV Reinforces a Poised Epigenetic Program for PD-1 Expression in Virus-specific CD8 T Cells
Ben Youngblood, A. Noto, F. Porichis, Rama S. Akondy +13 more
2013Journal of Immunology21 citations Open access
Semantic Scholar
Dual HLA B*42 and B*81-reactive T cell receptors recognize more diverse HIV-1 Gag escape variants
Funsho J. Ogunshola, Gursev Anmole, Rachel L. Miller, E. Goering +8 more
2018Nature Communications18 citations Open access
Semantic Scholar
Magnitude and Kinetics of CD 8 + T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point Highlights
Z. Ndhlovu, Philomena Kamya, N. Mewalal, H. Kløverpris +16 more
201517 citations
Semantic Scholar
T-Cell Receptor (TCR) Clonotype-Specific Differences in Inhibitory Activity of HIV-1 Cytotoxic T-Cell Clones Is Not Mediated by TCR Alone
Nina C Flerin, Hua-Biao Chen, Tynisha D. Glover, P. Lamothe +7 more
2017Journal of Virology15 citations Open access
Semantic Scholar
High resolution class I HLA-A, -B, and -C diversity in Eastern and Southern African populations
A. W. Banjoko, T. Ng’uni, Nitalia Naidoo, V. Ramsuran +2 more
2025Scientific Reports12 citations Open access
Semantic Scholar
Hypermethylation at the CXCR5 gene locus limits trafficking potential of CD8+ T cells into B-cell follicles during HIV-1 infection
Funsho J. Ogunshola, Werner Smidt, A. Naidoo, Thandeka Nkosi +14 more
2022Blood Advances11 citations Open access
Semantic Scholar
Subtle Longitudinal Alterations in Env Sequence Potentiate Differences in Sensitivity to Broadly Neutralizing Antibodies following Acute HIV-1 Subtype C Infection
Tawanda Mandizvo, Nombali Gumede, B. Ndlovu, Siphiwe Ndlovu +10 more
2022Journal of Virology9 citations Open access
Semantic Scholar
Oral abstracts of the 21st International AIDS Conference 18–22 July 2016, Durban, South Africa
A. Ericsen, M. Lauck, M. Mohns, S. Dinapoli +496 more
20167 citations Open access
Semantic Scholar
Differential localization and limited cytotoxic potential of duodenal CD8+ T cells
Leonard Mvaya, T. Khaba, A. Lakudzala, Thandeka Nkosi +8 more
2022JCI Insight6 citations Open access
Semantic Scholar
High Resolution Class I HLA -A, -B, and -C Diversity in Eastern and Southern African Populations
A. W. Banjoko, T. Ng’uni, Nitalia Naidoo, V. Ramsuran +2 more
2024bioRxiv5 citations Open access
Semantic Scholar
The impact of HIV infection on the frequencies, function, spatial localization and heterogeneity of T follicular regulatory cells (TFRs) within human lymph nodes
B. Mahlobo, F. Laher, Werner Smidt, Funsho J. Ogunshola +8 more
2022BMC Immunology5 citations Open access
Semantic Scholar
Low pre-existing endemic human coronavirus (HCoV-NL63)-specific T cell frequencies are associated with impaired SARS-CoV-2-specific T cell responses in people living with HIV
T. Ng’uni, Vernon Musale, Thandeka Nkosi, J. Mandolo +10 more
2024Frontiers in Immunology4 citations Open access
Semantic Scholar
Partial compartmentalisation of HIV-1 subtype C between lymph nodes, peripheral blood mononuclear cells and plasma
Neschika Jeewanraj, Tawanda Mandizvo, T. Mulaudzi, Nombali Gumede +4 more
2023Virology3 citations Open access
Semantic Scholar
Integrated Single-Cell Analysis of Multicellular Immune Dynamics during Hyper-Acute HIV-1 Infection
S. Kazer, T. Aicher, Daniel M. Muema, Shaina L. Carroll +12 more
2019bioRxiv3 citations Open access
Semantic Scholar
T cell receptor clonotypes modulate the protective effect of human leukocyte antigen class I alleles in HIV-1 infection
H. Chen, Z. Ndhlovu, D. Liu, L. Porter +17 more
2012Retrovirology3 citations Open access
Semantic Scholar
CD8+ T Cell Immunity in HIV Cure and Prevention: Linking Stemness, Spatial Niches, and Emerging Therapeutic Strategies.
A. Papadopoulos, Merantha Moodley, Crystal A. Mendoza, Z. Ndhlovu
2026Annual Review of Immunology2 citations Open access
Semantic Scholar
Meeting Summary for Keystone Symposia on HIV Cure: Antiretroviral Therapy (ART)-Free Control of HIV Infection in Durban, South Africa, 2025
Kiho Tanaka, T. J. Chikowore, S. Deeks, Jacob D. Estes +20 more
2025Pathogens and Immunity2 citations Open access
Semantic Scholar
Safety and practicality of an excisional lymph node study driving HIV cure research in South Africa
T. Khaba, A. Papadopoulos, Thandeka Nkosi, S. Nxele +4 more
2024Frontiers in Immunology2 citations Open access
Semantic Scholar
Injectable Contraceptive Use Correlates with Increased HIV Target Cells at the Cervix in Young South African Women
E. Byrne, Melis N. Anahtar, Kathleen E. Doherty, G. Olson +8 more
20142 citations Open access
Semantic Scholar
CD68+ Follicular Macrophages Harbor HIV Reservoirs in Human Lymph Node Tissues During Suppressive ART
Merantha Moodley, Caroline Chasara, T. Khaba, B. Mahlobo +9 more
2025bioRxiv1 citations Open access
Semantic Scholar
Limited Sequence Variation and Similar Phenotypic Characteristics of HIV-1 Subtype C Gag Variants Derived From the Reservoir and Pre-Therapy Plasma
D. Ojwach, K. Gounder, T. Mulaudzi, Nombali Gumede +7 more
2022Frontiers in Virology1 citations Open access
Semantic Scholar
Editing naive CD4+ T cells
A. O. Papadopoulos, Z. Ndhlovu
2021Nature Methods1 citations
Semantic Scholar
Magnitude and Kinetics of CD8[superscript +] T Cell Activation during Hyperacute HIV Infection Impact Viral Set Point
Z. Ndhlovu, Philomena Kamya, N. Mewalal, H. Kløverpris +17 more
20151 citations
Semantic Scholar
Massive Activation, Expansion and Subsequent Apoptosis of CD8 T-cells in Acute HIV Infection
Z. Ndhlovu, Philomena Kamya, N. Mewalal, Thandeka Nkosi +5 more
20141 citations
Semantic Scholar
T cell receptor clonotypes modulate the protective effect of HLA class I alleles in HIV-1 infection
Hua-Biao Chen, Z. Ndhlovu, Dongfang Liu, Lindsay C. Porter +17 more
20131 citations
Semantic Scholar
Cellular immune responses to measles virus-infection and vaccination
Z. Ndhlovu
20091 citations
Semantic Scholar
Prevalence and genotype distribution of human papillomavirus (HPV) among adolescent girls and young women in a high HIV burden rural area of South Africa: a cross-sectional survey
Maphe Mthembu, Kathy Baisley, J. Busang, Nqobile Ngoma +8 more
2026Research Square0 citations Open access
Semantic Scholar

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