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C. Spano · SciRah

Researcher profile · Semantic Scholar

C. Spano

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C. Spano — researcher profile on SciRah

h-index: 20
Works: 47
Citations: 1,818

Most-cited papers

Animal serum-free culture conditions for isolation and expansion of multipotent mesenchymal stromal cells from human BM.
I. Müller, Sandra Kordowich, C. Holzwarth, C. Spano +10 more
2006Cytotherapy255 citations
Semantic Scholar
Adipose-derived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy.
G. Grisendi, R. Bussolari, L. Cafarelli, I. Peták +16 more
2010Cancer Research233 citations Open access
Semantic Scholar
Restoration and reversible expansion of the osteoblastic hematopoietic stem cell niche after marrow radioablation.
M. Dominici, V. Rasini, R. Bussolari, Xiao-Hua Chen +8 more
2009Blood200 citations Open access
Semantic Scholar
Mesenchymal stem/stromal cells as a delivery platform in cell and gene therapies
N. D’souza, Filippo Rossignoli, G. Golinelli, G. Grisendi +7 more
2015BMC Medicine132 citations Open access
Semantic Scholar
Targeting GD2-positive glioblastoma by chimeric antigen receptor empowered mesenchymal progenitors
G. Golinelli, G. Grisendi, M. Prapa, M. Bestagno +9 more
2018Cancer Gene Therapy95 citations Open access
Semantic Scholar
A Novel 3D In Vitro Platform for Pre-Clinical Investigations in Drug Testing, Gene Therapy, and Immuno-oncology
O. Candini, G. Grisendi, E. Foppiani, Matteo Brogli +8 more
2019Scientific Reports84 citations Open access
Semantic Scholar
GD2 CAR T cells against human glioblastoma
M. Prapa, C. Chiavelli, G. Golinelli, G. Grisendi +15 more
2021npj Precision Oncology77 citations Open access
Semantic Scholar
Soluble TRAIL Armed Human MSC As Gene Therapy For Pancreatic Cancer
C. Spano, G. Grisendi, G. Golinelli, Filippo Rossignoli +18 more
2019Scientific Reports69 citations Open access
Semantic Scholar
A novel anti-GD2/4-1BB chimeric antigen receptor triggers neuroblastoma cell killing
M. Prapa, S. Caldrer, C. Spano, M. Bestagno +8 more
2015OncoTarget68 citations Open access
Semantic Scholar
Donor cell-derived osteopoiesis originates from a self-renewing stem cell with a limited regenerative contribution after transplantation.
M. Dominici, R. Marino, V. Rasini, C. Spano +4 more
2008Blood62 citations Open access
Semantic Scholar
Microglia are less pro‐inflammatory than myeloid infiltrates in the hippocampus of mice exposed to status epilepticus
J. Vinet, Ilia D. Vainchtein, C. Spano, Carmela Giordano +6 more
2016Glia61 citations Open access
Semantic Scholar
Mesenchymal Progenitors Aging Highlights a miR‐196 Switch Targeting HOXB7 as Master Regulator of Proliferation and Osteogenesis
O. Candini, C. Spano, A. Murgia, G. Grisendi +10 more
2015Stem Cells61 citations Open access
Semantic Scholar
Detection of microparticles from human red blood cells by multiparametric flow cytometry.
G. Grisendi, Elena Finetti, D. Manganaro, Nicoletta Cordova +8 more
2015Blood transfusion = Trasfusione del sangue58 citations
Semantic Scholar
Inducible Caspase9-mediated suicide gene for MSC-based cancer gene therapy
Filippo Rossignoli, G. Grisendi, C. Spano, G. Golinelli +6 more
2018Cancer Gene Therapy54 citations Open access
Semantic Scholar
GD2 expression in breast cancer
G. Orsi, M. Barbolini, G. Ficarra, G. Tazzioli +14 more
2017OncoTarget52 citations Open access
Semantic Scholar
Mesenchymal Progenitors Expressing TRAIL Induce Apoptosis in Sarcomas
G. Grisendi, C. Spano, N. D’souza, V. Rasini +14 more
2015Stem Cells47 citations Open access
Semantic Scholar
MSC-Delivered Soluble TRAIL and Paclitaxel as Novel Combinatory Treatment for Pancreatic Adenocarcinoma
Filippo Rossignoli, C. Spano, G. Grisendi, E. Foppiani +16 more
2019Theranostics46 citations Open access
Semantic Scholar
Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of smac/DIABLO from the mitochondria
K. Nagy, Kinga Székely-Szüts, K. Izeradjene, Leslie Douglas +10 more
2008Pathology and Oncology Research43 citations
Semantic Scholar
Human herpesvirus 8-associated diseases in solid-organ transplantation: importance of viral transmission from the donor.
M. Luppi, P. Barozzi, G. Guaraldi, L. Ravazzini +6 more
2003Clinical Infectious Diseases32 citations Open access
Semantic Scholar
Anti-GD2 CAR MSCs against metastatic Ewing's sarcoma
G. Golinelli, G. Grisendi, M. Dall’Ora, G. Casari +12 more
2021Translational Oncology21 citations Open access
Semantic Scholar
Autologous anti-GD2 CAR T cells efficiently target primary human glioblastoma
C. Chiavelli, M. Prapa, G. Rovesti, Marco Silingardi +19 more
2024npj Precision Oncology17 citations Open access
Semantic Scholar
Tumor Stroma Manipulation By MSC.
G. Grisendi, C. Spano, Filippo Rossignoli, Naomi D. Souza +7 more
2016Current Drug Targets15 citations Open access
Semantic Scholar
Combining gemcitabine and MSC delivering soluble TRAIL to target pancreatic adenocarcinoma and its stroma
G. Grisendi, M. Dall’Ora, G. Casari, Giliola Spattini +24 more
2024Cell Reports Medicine11 citations Open access
Semantic Scholar
Author Correction: A Novel 3D In Vitro Platform for Pre-Clinical Investigations in Drug Testing, Gene Therapy, and Immuno-oncology
O. Candini, G. Grisendi, E. Foppiani, Matteo Brogli +8 more
2020Scientific Reports7 citations Open access
Semantic Scholar
Surrounding Pancreatic Adenocarcinoma by Killer Mesenchymal Stromal/Stem Cells
G. Golinelli, G. Grisendi, C. Spano, M. Dominici
2014Human Gene Therapy7 citations Open access
Semantic Scholar
A 3D Platform to Investigate Dynamic Cell-to-Cell Interactions Between Tumor Cells and Mesenchymal Progenitors
G. Golinelli, R. Talami, S. Frabetti, O. Candini +6 more
2022Frontiers in Cell and Developmental Biology5 citations Open access
Semantic Scholar
GD 2 expression in breast cancer
G. Orsi, M. Barbolini, G. Ficarra, G. Tazzioli +14 more
20173 citations
Semantic Scholar
Impact of mesenchymal stromal/stem cell infusions on circulating inflammatory biomarkers in COVID-19 patients: analysis of a phase I-IIa trial.
R. Tonelli, F. Pischiutta, F. Elice, E. Zanier +35 more
2025Cytotherapy2 citations Open access
Semantic Scholar
Soluble TRAIL-Armed Human AD-MSC as Novel Cell Therapy
C. Spano, G. Grisendi, O. Candini, G. Golinelli +11 more
20162 citations Open access
Semantic Scholar
6TH International Conference on Lymphocyte Engineering 15–17 July 2026 Milan, Italy
T. Dao, Guang-Yan Xiong, Jeremy Meyerberg, Zita E H Aretz +363 more
2026Human Gene Therapy0 citations
Semantic Scholar
Immunotherapy: ANTI-GD2 CAR T CELLS AGAINST SMALL CELL LUNG CANCER
G. Neri, C. Chiavelli, L. Trudu, M. Prapa +12 more
2023Cytotherapy0 citations Open access
Semantic Scholar
Anti-GD2 chimeric antigen receptor & trail modified mesenchymal progenitors as novel strategy against ewing’s sarcoma
G. Golinelli, G. Grisendi, M. Dall’Ora, G. Casari +5 more
20210 citations Open access
Semantic Scholar
5P Anti-GD2 chimeric antigen receptor & TRAIL modified mesenchymal progenitors as novel strategy against Ewing’s sarcoma
G. Golinelli, G. Grisendi, M. Dall’Ora, G. Casari +5 more
20210 citations Open access
Semantic Scholar
Targeting pancreatic ductal adenocarcinoma & its stroma by a chemo & gene therapy strategy
G. Grisendi, M. Dall’Ora, Angela D'Esposito, G. Casari +5 more
2020Cytotherapy0 citations Open access
Semantic Scholar
From laboratory to patients: dissecting obstacles in cell & gene therapy development
D. N. Silva, C. Spano, M. Varricchio, G. Grisendi +3 more
20200 citations Open access
Semantic Scholar
Abstract A17: Challenging pancreatic ductal adenocarcinoma and its stroma by a combination of chemo and gene therapy: A preclinical study
G. Grisendi, M. Dall’Ora, Angela D'Esposito, Giulia Casaria +5 more
20190 citations Open access
Semantic Scholar
Targeting GD2-positive glioblastoma by chimeric antigen receptor empowered mesenchymal progenitors
G. Golinelli, G. Grisendi, M. Prapa, M. Bestagno +9 more
2018Cancer Gene Therapy0 citations Open access
Semantic Scholar
Adoptive CAR T Cell Therapy Targeting GD2-Positive Cancers
M. Prapa, D. Cerioli, S. Caldrer, C. Spano +10 more
20160 citations Open access
Semantic Scholar
Age related miRNA signature in mesenchymal progenitors reveals key players in cellular performance and fate
O. Candini, C. Spano, E. Foppiani, G. Grisendi +8 more
20150 citations
Semantic Scholar
Modified adipose mesenchymal progenitors target Ewing's sarcoma
G. Grisendi, C. Spano, N. D’souza, V. Rasini +7 more
20140 citations
Semantic Scholar
stem cell niche after marrow radioablation Restoration and reversible expansion of the osteoblastic hematopoietic
D. Bernabei, Elena Veronesi, F. Bertoni, P. Paolucci +6 more
20090 citations
Semantic Scholar
0.1 Grams of Sub-Cutaneous Adipose Tissue (SCAT) as Source of Adult Multipotent Mesenchymal Stromal Cells (MSC) for Cell-Based Therapies.
M. Dominici, Rita Sternieri, D. De Fazio, L. Cafarelli +10 more
20070 citations Open access
Semantic Scholar
Grams of Sub-Cutaneous Adipose Tissue (SCAT) as Source of Adult Multipotent Mesenchymal Stromal Cells (MSC) for Cell-Based Therapies
M. Dominici, Rita Sternieri, D. De Fazio, L. Cafarelli +10 more
20070 citations
Semantic Scholar
Human multipotent mesenchymal stromal cells (MSCs) induce proliferation of allogeneic peripheral blood mononuclear cells.
M. Dominici, V. Rasini, Rita Sternieri, L. Cafarelli +10 more
20060 citations
Semantic Scholar
SMALL VOLUMES OF SUBCUTANEOUS ADIPOSE TISSUE AS SOURCE OF ADULT MESENCHIMAL STEM CELLS FOR REGENERATIVE MEDICINE AND CANCER CELL-THERAPIES
M. Dominici, L. Caffarelli, G. Guaraldi, Sandra Kordowich +9 more
20050 citations
Semantic Scholar
A NOVEL SERUM DEPRIVED MEDIUM FOR ISOLATION AND EXPANSION OF FUNCTIONAL DIFFERENTIATING MESENCHYMAL STEM CELLS
I. Mariotti, S. Spaggiari, A. Bonetti, M. Dominici +7 more
20050 citations
Semantic Scholar
Isolation and Expansion of Functional Differentiating Mesenchymal Stem Cells with a Serum Deprived Medium.
M. Dominici, I. Mueller, L. Cafarelli, Sandra Kordowich +8 more
20040 citations Open access
Semantic Scholar

Frequent co-authors

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G. Golinelli×21
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P. Paolucci×18

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O. Candini — researcher profile on SciRah

Elena Veronesi×13

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Filippo Rossignoli — researcher profile on SciRah

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V. Rasini — researcher profile on SciRah