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N. Sorel · SciRah

Researcher profile · Semantic Scholar

N. Sorel

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N. Sorel — researcher profile on SciRah

h-index: 16
Works: 67
Citations: 1,414

Most-cited papers

Mutation status and clinical outcome of 89 imatinib mesylate-resistant chronic myelogenous leukemia patients: a retrospective analysis from the French intergroup of CML (Fi(ϕ)-LMC GROUP)
F. Nicolini, S. Corm, Q. Le, N. Sorel +14 more
2006Leukemia238 citations
Semantic Scholar
Leukemic stem cell persistence in chronic myeloid leukemia patients with sustained undetectable molecular residual disease.
J. Chomel, M. Bonnet, N. Sorel, A. Bertrand +6 more
2011Blood220 citations Open access
Semantic Scholar
Resistance to aspirin in vitro is associated with increased platelet sensitivity to adenosine diphosphate.
L. Macchi, L. Christiaens, S. Brabant, N. Sorel +3 more
2002Thrombosis Research204 citations
Semantic Scholar
Resistance in vitro to low-dose aspirin is associated with platelet PlA1 (GP IIIa) polymorphism but not with C807T(GP Ia/IIa) and C-5T Kozak (GP Ibalpha) polymorphisms.
L. Macchi, L. Christiaens, S. Brabant, N. Sorel +4 more
2003Journal of the American College of Cardiology173 citations Open access
Semantic Scholar
Leukemic stem cell persistence in chronic myeloid leukemia patients in deep molecular response induced by tyrosine kinase inhibitors and the impact of therapy discontinuation
J. Chomel, M. Bonnet, N. Sorel, I. Sloma +9 more
2016OncoTarget66 citations Open access
Semantic Scholar
Aspirin resistance: definitions, mechanisms, prevalence, and clinical significance.
L. Macchi, N. Sorel, Luc-Philippe Christiaens
2006Current pharmaceutical design66 citations
Semantic Scholar
Evidence of ABL-kinase domain mutations in highly purified primitive stem cell populations of patients with chronic myelogenous leukemia.
N. Sorel, M. Bonnet, M. Guillier, F. Guilhot +2 more
2004Biochemical and Biophysical Research Communications - BBRC54 citations
Semantic Scholar
Neutrophil gelatinase-associated lipocalin expression in chronic myeloid leukemia
C. Villalva, N. Sorel, M. Bonnet, J. Guilhot +4 more
2008Leukemia and Lymphoma38 citations
Semantic Scholar
Double-gradient-denaturing-gradient gel electrophoresis for mutation screening of the BCR-ABL tyrosine kinase domain in chronic myeloid leukemia patients.
N. Sorel, Florence Chazelas, A. Brizard, J. Chomel
2005Clinical Chemistry31 citations
Semantic Scholar
BCR-ABL expression in leukemic progenitors and primitive stem cells of patients with chronic myeloid leukemia.
J. Chomel, N. Sorel, J. Guilhot, F. Guilhot +1 more
2012Blood24 citations
Semantic Scholar
p190(BCR-ABL) rearrangement as a secondary change in a case of acute myelo-monocytic leukemia with inv(16)(p13q22).
M. Cividin, F. Brizard, N. Sorel, M. Renaud +2 more
2004Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis24 citations
Semantic Scholar
The downregulation of BAP1 expression by BCR-ABL reduces the stability of BRCA1 in chronic myeloid leukemia.
F. Dkhissi, D. Aggoune, Julien Pontis, N. Sorel +6 more
2015Experimental Hematology23 citations Open access
Semantic Scholar
Bone marrow mesenchymal stromal cell (MSC) gene profiling in chronic myeloid leukemia (CML) patients at diagnosis and in deep molecular response induced by tyrosine kinase inhibitors (TKIs).
D. Aggoune, N. Sorel, M. Bonnet, J. Goujon +12 more
2017Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis20 citations
Semantic Scholar
p14ARF, p15INK4b, and p16INK4a methylation status in chronic myelogenous leukemia.
Sophie Kusy, M. Cividin, N. Sorel, F. Brizard +4 more
2003Blood20 citations Open access
Semantic Scholar
Modeling the influence of stromal microenvironment in the selection of ENU-induced BCR-ABL1 mutants by tyrosine kinase inhibitors
D. Aggoune, L. Tosca, N. Sorel, M. Bonnet +5 more
2014Oncoscience19 citations Open access
Semantic Scholar
Extensive analysis of the T315I substitution and detection of additional ABL mutations in progenitors and primitive stem cell compartment in a patient with tyrosine kinase inhibitor-resistant chronic myeloid leukemia
J. Chomel, N. Sorel, M. Bonnet, A. Bertrand +4 more
2010Leukemia and Lymphoma17 citations
Semantic Scholar
Quantitative monitoring of the T315I mutation in patients with chronic myeloid leukemia (CML).
J. Chomel, N. Sorel, M. Bonnet, A. Bertrand +5 more
2009Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis16 citations
Semantic Scholar
Comprehensive characterization of a novel intronic pseudo-exon inserted within an e14/a2 BCR-ABL rearrangement in a patient with chronic myeloid leukemia.
N. Sorel, C. Mayeur-Rousse, Séverine Deverrière, L. Roy +4 more
2010Journal of Molecular Diagnostics13 citations Open access
Semantic Scholar
Unique association of systemic mastocytosis and myeloid/lymphoid neoplasm in blast crisis with abnormality of FGFR1 gene.
C. Mayeur-Rousse, N. Sorel, M. Voldoire, D. Canioni +4 more
2012Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis10 citations
Semantic Scholar
ETV6 (TEL) gene amplification in a myelodysplastic syndrome with excess of blasts
L. Mauvieux, C. Hélias, N. Perrusson, B. Lioure +3 more
2004Leukemia10 citations
Semantic Scholar
Superoxide dismutase 2 (SOD2) contributes to genetic stability of native and T315I-mutated BCR-ABL expressing leukemic cells.
Sandrine Girerd, L. Tosca, O. Hérault, C. Vignon +12 more
2018Biochemical and Biophysical Research Communications - BBRC9 citations
Semantic Scholar
Stroke and aspirin non-responder patients: Relation with hypertension and platelet response to adenosine diphosphate
G. Godenèche, N. Sorel, Stéphanie Ragot, J. Chomel +2 more
2009Platelets9 citations
Semantic Scholar
Sequential emergence of ABL-kinase mutations with loss of unmutated BCR-ABL allele during targeted therapies of CML.
N. Sorel, L. Roy, G. Martineau, F. Guilhot +2 more
2006Blood9 citations
Semantic Scholar
Deciphering Potential Molecular Signatures to Differentiate Acute Myeloid Leukemia (AML) with BCR::ABL1 from Chronic Myeloid Leukemia (CML) in Blast Crisis
Lara Boucher, N. Sorel, Christophe Desterke, Mélanie Chollet +7 more
2023International Journal of Molecular Sciences8 citations Open access
Semantic Scholar
Sustained molecular response in chronic myeloid leukemia deep responders treated with low dose tyrosine kinase inhibitors
E. Cayssials, F. Tartarin, J. Guilhot, N. Sorel +3 more
2018Leukemia and Lymphoma8 citations
Semantic Scholar
Experimental and integrative analyses identify an ETS1 network downstream of BCR-ABL in chronic myeloid leukemia (CML).
C. Desterke, M. Voldoire, M. Bonnet, N. Sorel +6 more
2018Experimental Hematology8 citations Open access
Semantic Scholar
Treatment and molecular monitoring update in chronic myeloid leukemia management.
N. Sorel, E. Cayssials, F. Brizard, J. Chomel
2017Annales de Biologie Clinique8 citations
Semantic Scholar
Long‐term molecular remission in a patient with acute myeloid leukemia harboring a new NUP98‐LEDGF rearrangement
M. P. Gallego Hernanz, J. Torregrosa Diaz, N. Sorel, A. Bobin +7 more
2019Cancer Medicine7 citations Open access
Semantic Scholar
Biological effects of T315I-mutated BCR-ABL in an embryonic stem cell-derived hematopoiesis model.
Michael Melkus, A. Bennaceur-Griscelli, Yannick Valogne, S. Flamant +6 more
2013Experimental Hematology6 citations Open access
Semantic Scholar
Modeling Blast Crisis Using Mutagenized Chronic Myeloid Leukemia-Derived Induced Pluripotent Stem Cells (iPSCs)
J. Imeri, C. Desterke, P. Marcoux, G. Telliam +10 more
2023Cells5 citations Open access
Semantic Scholar
Therapy-related acute lymphoblastic leukemia with MLL rearrangement following treatment of Burkitt's leukemia
F. Millot, F. Brizard, N. Sorel, C. Preudhomme +3 more
2005Leukemia and Lymphoma5 citations
Semantic Scholar
A rapid and specific whole blood HPA‐1 phenotyping by flow cytometry using two commercialized monoclonal antibodies directed against GP IIIa and GP IIb‐IIIa complexes
N. Sorel, S. Brabant, L. Christiaens, A. Brizard +2 more
2004British Journal of Haematology5 citations
Semantic Scholar
ENOX2 NADH Oxidase: A BCR-ABL1-Dependent Cell Surface and Secreted Redox Protein in Chronic Myeloid Leukemia
Seda Baykal-Köse, M. Voldoire, C. Desterke, N. Sorel +6 more
2021bioRxiv4 citations Open access
Semantic Scholar
Evidence of BCR-ABL1-positive progenitor spread in blood during molecular recurrence after TKI discontinuation in chronic myeloid leukemia (CML)
A. Turhan, P. Hugues, N. Sorel, C. Desterke +3 more
2020Leukemia and Lymphoma4 citations Open access
Semantic Scholar
Expression of the cell cycle regulators p14(ARF) and p16(INK4a) in chronic myeloid leukemia.
M. Cividin, O. Ayrault, N. Sorel, P. Séité +7 more
2006Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis4 citations
Semantic Scholar
Mutation Status of Imatinib Mesylate-Resistants CML Patients and Clinical Outcomes: A French Multicenter Retrospective Study for the fiLMC Group.
S. Corm, F. Nicollini, D. Borie, N. Sorel +12 more
20044 citations
Semantic Scholar
Relationship between C-5T Kozak, C807T Genotypes and Expression of Glycoproteins Ibα and Ia-IIa at Platelet Surface: From Genotype to Phenotype
L. Macchi, N. Sorel, S. Brabant, L. Christiaens +1 more
2002Thrombosis and Haemostasis4 citations
Semantic Scholar
Expression of the cell cycle regulators p14ARF and p16INK4a in chronic myeloid leukemia
M. Cividin, O. Ayrault, N. Sorel, P. Séité +7 more
20063 citations
Semantic Scholar
Emergence of secondary fusions in chronic myeloid leukemia as a driver of tyrosine kinase inhibitor resistance and blast crisis transformation.
Lara Boucher, Laura Rozalska, N. Sorel, G. Olivier +4 more
2024Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis2 citations
Semantic Scholar
Identification and genetic characterization of a NUP98-HHEX molecular rearrangement in a pediatric acute myeloid leukemia
N. Sorel, A. Raimbault, F. Brizard, Thibault Depaire +5 more
2021Leukemia and Lymphoma2 citations
Semantic Scholar
Superoxide Dismutase 2 (Sod2) Expression Is Highly Decreased In Chronic Myeloid Leukemia (CML): Contribution To Genetic Instability In Bcr-Abl-Expressing Leukemic Cells
Sandrine Girerd, L. Tosca, O. Hérault, C. Vignon +11 more
20132 citations
Semantic Scholar
Evaluation of Leukemic Stem Cell Persistence in Chronic Myeloid Leukemia (CML) Patients in Complete Molecular Remission Induced by First Line TKI Therapies
J. Chomel, M. Bonnet, N. Sorel, I. Sloma +10 more
20122 citations
Semantic Scholar
ABL-Kinase Mutations in Progenitors and Stem Cells from Chronic Myeloid Leukemia Patients
J. Chomel, N. Sorel, A. Turhan
20122 citations
Semantic Scholar
Persistence of BCR-ABL-Expressing LEUKEMIC STEM CELLS IN Chronic MYELOID LEUKEMIA (CML) PATIENTS IN COMPLETE REMISSION with Undetectable MOLECULAR Disease
J. Chomel, M. Bonnet, N. Sorel, A. Bertrand +5 more
20102 citations
Semantic Scholar
Evaluation of β-Catenin activating mutations in chronic myeloid leukemia
J. Chomel, C. Villalva, N. Sorel, Florence Chazelas +2 more
20082 citations
Semantic Scholar
Evaluation of beta-catenin activating mutations in chronic myeloid leukemia.
J. Chomel, C. Villalva, N. Sorel, Florence Chazelas +2 more
2008Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis2 citations
Semantic Scholar
Clinical Outcome of 27 Imatinib Mesylate Resistant Chronic Myelogenous Leukemia (CML) Patients Harbouring a T315I BCR-ABL Mutation.
F. Nicolini, Emmanuel Bachy, S. Corm, Q. Le +12 more
20062 citations
Semantic Scholar
The Cell Surface NADH Oxidase ENOX2 Is Highly Expressed in Chronic Myeloid Leukemia (CML): a Redox Protein As a Secreted Surrogate Biomarker and Druggable Target
Seda Baykal, M. Voldoire, C. Desterke, N. Sorel +5 more
20161 citations
Semantic Scholar
ETS1 Expression Is Upregulated in Chronic Myeloid Leukemia (CML) and the ETS1 Transcriptional Program Correlates with Disease Progression Towards Blast Crisis
C. Desterke, M. Voldoire, N. Sorel, M. Bonnet +5 more
20161 citations
Semantic Scholar
A Niche-Based Cell Mutagenesis Assay Identifies ABL-Kinase Mutations Appearing in BCR-ABL T315I-Mutated Leukemic Cells Treated with Ponatinib.
D. Aggoune, N. Sorel, M. Bonnet, J. Chomel +1 more
20121 citations
Semantic Scholar

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