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D. Bibby · SciRah

Researcher profile · Semantic Scholar

D. Bibby

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D. Bibby — researcher profile on SciRah

h-index: 13
Works: 43
Citations: 987

Most-cited papers

Mechanisms by which cyclodextrins modify drug release from polymeric drug delivery systems.
D. Bibby, N. Davies, I. Tucker
2000International journal of pharmaceutics290 citations
Semantic Scholar
In vitro study of GDNF release from biodegradable PLGA microspheres.
A. Aubert-Pouëssel, M. Venier-Julienne, A. Clavreul, M. Sergent +6 more
2004Journal of Controlled Release137 citations
Semantic Scholar
Pharmacokinetics and biodistribution of RGD-targeted doxorubicin-loaded nanoparticles in tumor-bearing mice.
D. Bibby, J. Talmadge, M. Dalal, S. Kurz +4 more
2005International journal of pharmaceutics133 citations
Semantic Scholar
A Novel in Vitro Delivery System for Assessing the Biological Integrity of Protein upon Release from PLGA Microspheres
A. Aubert-Pouëssel, D. Bibby, M. Venier-Julienne, F. Hindré +1 more
2002Pharmaceutical Research75 citations
Semantic Scholar
Clinical, Pharmacodynamic, and Pharmacokinetic Evaluation of BNC105P: A Phase I Trial of a Novel Vascular Disrupting Agent and Inhibitor of Cancer Cell Proliferation
D. Rischin, D. Bibby, G. Chong, G. Kremmidiotis +5 more
2011Clinical Cancer Research51 citations Open access
Semantic Scholar
A phase II clinical trial of the vascular disrupting agent BNC105P as second line chemotherapy for advanced Malignant Pleural Mesothelioma.
A. Nowak, Chris Brown, M. Millward, J. Creaney +9 more
2013Lung Cancer50 citations
Semantic Scholar
Temperature and metabolic changes in rats after various doses of tumour necrosis factor alpha.
D. Bibby, R. Grimble
1989Journal of Physiology40 citations Open access
Semantic Scholar
Encapsulation of protamine sulphate compacted DNA in polylactide and polylactide-co-glycolide microparticles.
M. Dunne, D. Bibby, Joanna C. Jones, S. Cudmore
2003Journal of Controlled Release38 citations
Semantic Scholar
A phase I/II trial of BNC105P with everolimus in metastatic renal cell carcinoma (mRCC)
S. Pal, A. Azad, S. Bhatia, H. Drabkin +18 more
2015Clinical Cancer Research29 citations Open access
Semantic Scholar
Poly(acrylic acid) microspheres containing beta-cyclodextrin: loading and in vitro release of two dyes.
D. Bibby, N. Davies, I. Tucker
1999International journal of pharmaceutics29 citations
Semantic Scholar
Investigations into the structure and composition of beta-cyclodextrin/poly(acrylic acid) microspheres.
D. Bibby, N. M. Davies, Ian G. Tucker
1999International journal of pharmaceutics20 citations
Semantic Scholar
Interlaboratory Reproducibility of Standardized Hemagglutination Inhibition Assays
D. Bibby, Michael Savanovic, Jin-Rong Zhang, A. Torelli +3 more
2022Msphere16 citations Open access
Semantic Scholar
Preparation and characterization of β-cyclodextrin and poly(acrylic acid) microspheres
D. Bibby, N. Davies, I. Tucker
199814 citations
Semantic Scholar
Effect of age on hypothalamic prostaglandin E2 production and fever in response to tumour necrosis factor (cachectin) and endotoxin in rats.
D. Bibby, R. Grimble
1991Clinical science12 citations
Semantic Scholar
Synthesis and evaluation of 5′ alkyl ester prodrugs of zidovudine for directed lymphatic delivery
D. Bibby, W. Charman, S. Charman, M. Iskander +1 more
199611 citations
Semantic Scholar
Tumour necrosis factor-alpha and endotoxin induce less prostaglandin E2 production from hypothalami of rats fed coconut oil than from hypothalami of rats fed maize oil.
D. Bibby, R. Grimble
1990Clinical science9 citations
Semantic Scholar
Effects of urethane, ambient temperature and injection route on rat body temperature and metabolism due to endotoxins.
D. Bibby, R. Grimble
1988Journal of Physiology8 citations Open access
Semantic Scholar
Dietary fat modifies some metabolic actions of human recombinant tumour necrosis factor α in rats
D. Bibby, R. Grimble
1990British Journal of Nutrition7 citations Open access
Semantic Scholar
Abstract 2774: Anti-cancer activity of the tumor-selective, hypoxia-inducing, agent BNC105 in platinum resistant ovarian cancer
T. Lavranos, A. Leske, Daniel J. Inglis, C. Brown +2 more
20124 citations
Semantic Scholar
Phase I, pharmacokinetic, and pharmacodynamic evaluation of BNC105P, a novel anticancer agent that is both a vascular disrupting agent (VDA) and an inhibitor of cancer cell proliferation.
J. Desai, Shirley S. Wong, G. Chong, D. Bibby +4 more
2009Journal of Clinical Oncology4 citations
Semantic Scholar
A first-in-human, phase I pharmacodynamic (PD) and pharmacokinetic (PK) study of BNC105P, a novel vascular disrupting agent (VDA) and inhibitor of cancer cell proliferation.
G. Chong, J. Desai, D. Bibby, G. Kremmidiotis +5 more
20103 citations
Semantic Scholar
Phase I/II study of a BNC105P/everolimus regimen for progressive metastatic renal cell carcinoma (mRCC) following prior tyrosine kinase inhibitors (Hoosier Oncology Group).
Thomas E. Hutson, L. Dang, R. Lauer, A. Starodub +13 more
2012Journal of Clinical Oncology2 citations
Semantic Scholar
A phase I/II trial of BNC105P with everolimus in metastatic renal cell carcinoma (mRCC) patients: Updated phase I results of the Disruptor-1 trial.
J. Sarantopoulos, L. Dang, R. Lauer, A. Starodub +14 more
20131 citations
Semantic Scholar
Phase I/II study of BNC105P in combination with everolimus or following everolimus for progressive metastatic renal cell carcinoma following prior tyrosine kinase inhibitors.
Thomas E. Hutson, J. Sarantopoulos, T. Logan, G. Sonpavde +6 more
2011Journal of Clinical Oncology1 citations
Semantic Scholar
Functional and molecular biomarker analysis demonstrates pharmacological activity for the novel vascular disrupting agent BNC105 in a first in human clinical study
D. Bibby, J. Desai, G. Chong, G. Kremmidiotis +5 more
20111 citations
Semantic Scholar
Discovery and clinical development of BNC105, a tubulin targeting small molecule that selectively disrupts the vasculature in solid tumours
A. Leske, D. Bibby, T. Lavranos, Donna M. Beaumont +7 more
20111 citations
Semantic Scholar
Encapsulation of recombinant hepatitis B surface antigen in oligosaccharide ester derivatives by spray drying
R. Alcock, D. Bibby, T. G. Gard
2003Journal of Microencapsulation1 citations
Semantic Scholar
Synthesis and characterisation of poly(acrylic acid) microspheres containing β-cyclodextrin
D. Bibby
19991 citations
Semantic Scholar
Association of baseline IL-8 and ferritin with clinical outcome with everolimus and BNC105P in the DisrupTOR-1 trial.
S. Pal, A. Azad, S. Bhatia, H. Drabkin +16 more
20150 citations
Semantic Scholar
P0125 A phase 1/2 trial of BNC105P with everolimus in metastatic renal cell carcinoma
S. Pal, A. Azad, S. Bhatia, H. Drabkin +16 more
20150 citations
Semantic Scholar
815PDA PHASE I/II TRIAL OF BNC105P WITH EVEROLIMUS IN METASTATIC RENAL CELL CARCINOMA (MRCC): RESULTS OF THE RANDOMIZED PHASE II DISRUPTOR-1 TRIAL.
S. Pal, A. Azad, S. Bhatia, H. Drabkin +15 more
2014Annals of Oncology0 citations Open access
Semantic Scholar
A phase I/II study of the vascular disrupting agent BNC105P in combination with gemcitabine-carboplatin in partially platinum-sensitive ovarian cancer patients in first or second relapse: An international collaborative group trial of ANZGOG and HOG.
D. Rischin, D. Matei, Jeffrey C. Goh, M. Vaughan +10 more
20130 citations
Semantic Scholar
Updated phase I results of a phase I/II trial of BNC105P with everolimus in patients with metastatic renal cell carcinoma (mRCC).
Thomas E. Hutson, L. Dang, R. Lauer, A. Starodub +13 more
2013Journal of Clinical Oncology0 citations
Semantic Scholar
Phase II trial of BNC105P as second-line chemotherapy for advanced malignant pleural mesothelioma (MPM): Australasian Lung Cancer Trials Group and NHMRC Clinical Trials Centre Collaboration.
A. Nowak, Christopher D. Brown, M. Millward, B. Hughes +12 more
20120 citations
Semantic Scholar
Phase I results of a phase I/II trial of BNC105P with everolimus in metastatic renal cell carcinoma (mRCC) patients previously treated with VEGFR tyrosine kinase inhibitors.
Thomas E. Hutson, L. Dang, R. Lauer, A. Starodub +13 more
20120 citations
Semantic Scholar
Phase I/II study of a BNC105P/everolimus regimen for progressive metastatic renal cell carcinoma (mRCC) following prior tyrosine kinase inhibitors (Hoosier Oncology Group).
Thomas E. Hutson, L. Dang, R. Lauer, A. Starodub +13 more
2012Journal of Clinical Oncology0 citations
Semantic Scholar
Bibby 2005 - Pk of dox-NPs - IntJPharm 293, 281
D. Bibby, J. Talmadge, M. Dalal, S. Kurz +4 more
20120 citations
Semantic Scholar
Cancer Therapy : Clinical Clinical , Pharmacodynamic , and Pharmacokinetic Evaluation of BNC 105 P : A Phase I Trial of a Novel Vascular Disrupting Agent and Inhibitor of Cancer Cell Proliferation
D. Rischin, D. Bibby, G. Chong, G. Kremmidiotis +5 more
20110 citations
Semantic Scholar
Abstract 2768: Development of a tubulin fractionation assay for the evaluation of “on target” activity of tubulin targeting agents in clinical PBMC samples
C. Matthews, D. Bibby, A. Leske, A. Harvey +1 more
20100 citations
Semantic Scholar
Combination therapy for the treatment of proliferative diseases
G. Kremmidiotis, D. Bibby, A. Leske
20100 citations
Semantic Scholar
Abstract #5564: BNC105 is a tubulin targeting agent that is not susceptible to efflux by Pgp transporter expression, and yields additive therapeutic benefit when combined with other anti-cancer agents
G. Kremmidiotis, Donna M. Beaumont, C. Matthews, J. Gasic +4 more
20090 citations
Semantic Scholar
Pharmacology, toxicology and efficacy of cyclic RGD targeted nanoparticles with covalently attached doxorubicin
J. Talmadge, S. Kurz, Amy W. Hsu, M. Dalal +4 more
20040 citations
Semantic Scholar
Preparation and characterization of beta-cyclodextrin and poly(acrylic acid) microspheres.
D. Bibby, N. Davies, I. Tucker
1998Journal of Microencapsulation0 citations
Semantic Scholar

Frequent co-authors

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G. Kremmidiotis×22
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G. Kremmidiotis — researcher profile on SciRah
A. Leske×15
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A. Leske — researcher profile on SciRah
E. Doolin×11
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E. Doolin — researcher profile on SciRah
N. Hahn×10
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N. Hahn — researcher profile on SciRah

×10

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G. Sonpavde — researcher profile on SciRah

Thomas E. Hutson×10

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Thomas E. Hutson — researcher profile on SciRah

J. Sarantopoulos×9

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J. Sarantopoulos — researcher profile on SciRah

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R. Lauer — researcher profile on SciRah

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C. Sweeney — researcher profile on SciRah

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T. Lavranos — researcher profile on SciRah

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D. Rischin — researcher profile on SciRah

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G. Chong — researcher profile on SciRah