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C. Goldsmith · SciRah

Researcher profile · Semantic Scholar

C. Goldsmith

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C. Goldsmith — researcher profile on SciRah

h-index: 26
Works: 54
Citations: 2,020

Most-cited papers

Early responses to adenoviral-mediated transfer of the aquaporin-1 cDNA for radiation-induced salivary hypofunction
B. Baum, I. Alevizos, Chang-Yu Zheng, Ana P. Cotrim +18 more
2012Proceedings of the National Academy of Sciences of the United States of America192 citations Open access
Semantic Scholar
Increased fluid secretion after adenoviral-mediated transfer of the human aquaporin-1 cDNA to irradiated miniature pig parotid glands.
Z. Shan, Jun Li, Chang-Yu Zheng, Xiaoyong Liu +6 more
2005Molecular Therapy128 citations Open access
Semantic Scholar
Endogenous osteonectin/SPARC/BM-40 expression inhibits MDA-MB-231 breast cancer cell metastasis.
Jennifer E. Koblinski, Benjamin Kaplan-Singer, S. VanOsdol, Michael Wu +8 more
2005Cancer Research123 citations Open access
Semantic Scholar
STIM2 enhances receptor-stimulated Ca2+ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions
H. L. Ong, L. de Souza, Chang-Yu Zheng, Kwong-Tai Cheng +4 more
2015Science Signaling101 citations Open access
Semantic Scholar
Reengineered salivary glands are stable endogenous bioreactors for systemic gene therapeutics.
A. Voutetakis, M. Kok, Chang-Yu Zheng, I. Bossis +8 more
2004Proceedings of the National Academy of Sciences of the United States of America100 citations Open access
Semantic Scholar
Systemic action of human growth hormone following adenovirus-mediated gene transfer to rat submandibular glands
Xin-Jun He, C. Goldsmith, Yitzhak Marmary, Robert B. Wellner +3 more
1998Gene Therapy92 citations Open access
Semantic Scholar
Insulin-like Growth Factor-I (IGF-I) Receptor Activation Rescues UV-damaged Cells through a p38 Signaling Pathway
L. Héron-Milhavet, M. Karas, C. Goldsmith, B. Baum +1 more
2001Journal of Biological Chemistry86 citations Open access
Semantic Scholar
Primary Culture of Polarized Human Salivary Epithelial Cells for Use in Developing an Artificial Salivary Gland
S. Tran, J. Wang, Bidhan C. Bandyopadhyay, R. Redman +10 more
2005Tissue engineering84 citations
Semantic Scholar
Transfer of the AQP1 cDNA for the correction of radiation-induced salivary hypofunction.
B. Baum, Chang-Yu Zheng, Ana P. Cotrim, C. Goldsmith +11 more
2006Biochimica et Biophysica Acta71 citations Open access
Semantic Scholar
AAV2-mediated transfer of the human aquaporin-1 cDNA restores fluid secretion from irradiated miniature pig parotid glands
Run-Tao Gao, Xing Yan, Chang-Yu Zheng, C. Goldsmith +8 more
2010Gene Therapy70 citations Open access
Semantic Scholar
Development of a gene transfer-based treatment for radiation-induced salivary hypofunction
B. Baum, Chang-Yu Zheng, I. Alevizos, Ana P. Cotrim +7 more
2009Oral Oncology63 citations Open access
Semantic Scholar
Late responses to adenoviral-mediated transfer of the aquaporin-1 gene for radiation-induced salivary hypofunction
I. Alevizos, Chang-Yu Zheng, Ana P. Cotrim, Shuying Liu +14 more
2016Gene Therapy61 citations Open access
Semantic Scholar
Polarized Secretion of Transgene Products from Salivary Glands in Vivo
Bruce J. Baum, Mark E. Berkman, Yitzhak Marmary, C. Goldsmith +9 more
1999Human Gene Therapy54 citations
Semantic Scholar
Recombinant Adeno-Associated Virus Serotype 2 Vectors Mediate Stable Interleukin 10 Secretion from Salivary Glands into the Bloodstream
S. Yamano, Li-Yun Huang, C. Ding, J. Chiorini +6 more
2002Human Gene Therapy48 citations
Semantic Scholar
CERE-120 Prevents Irradiation-Induced Hypofunction and Restores Immune Homeostasis in Porcine Salivary Glands
I. Lombaert, V. Patel, Christine Jones, De Villier +14 more
2020Molecular Therapy: Methods & Clinical Development46 citations Open access
Semantic Scholar
Aquaporin-1 Gene Transfer to Correct Radiation-Induced Salivary Hypofunction
Bruce J. Baum, Chang-Yu Zheng, Ana P. Cotrim, Linda M. McCullagh +7 more
2009Handbook of Experimental Pharmacology44 citations Open access
Semantic Scholar
Developing a convenient large animal model for gene transfer to salivary glands in vivo
Jun Li, Chanyu Zheng, Xin Zhang, Xiaoyong Liu +4 more
2004Journal of Gene Medicine44 citations
Semantic Scholar
Cationic liposome‐mediated gene transfer to rat salivary epithelial cells in vitro and in vivo
L. Baccaglini, A. T. M. Shamsul Hoque, Robert B. Wellner, C. Goldsmith +6 more
2001Journal of Gene Medicine42 citations
Semantic Scholar
Toxicity and Biodistribution of a First-Generation Recombinant Adenoviral Vector, Encoding Aquaporin-1, After Retroductal Delivery to a Single Rat Submandibular Gland
Chang-Yu Zheng, C. Goldsmith, Fumi Mineshiba, J. Chiorini +5 more
2006Human Gene Therapy41 citations
Semantic Scholar
Evidence that aquaporin-8 is located in the basolateral membrane of rat submandibular gland acinar cells
Robert B. Wellner, A. T. Hoque, C. Goldsmith, BJ Baum
2000Pflügers Archiv40 citations
Semantic Scholar
Relationship between adenovirus-mediated aquaporin 1 expression and fluid movement across epithelial cells.
Christine Delporte, A. T. M. Shamsul Hoque, Jill A. Kulakusky, Virginia R. Braddon +3 more
1998Biochemical and Biophysical Research Communications - BBRC40 citations
Semantic Scholar
Neurturin Gene Therapy Protects Parasympathetic Function to Prevent Irradiation-Induced Murine Salivary Gland Hypofunction
João N. Ferreira, Chang-Yu Zheng, I. Lombaert, C. Goldsmith +4 more
2018Molecular Therapy: Methods & Clinical Development34 citations Open access
Semantic Scholar
Female mice are more susceptible to developing inflammatory disorders due to impaired transforming growth factor beta signaling in salivary glands.
S. Nandula, Shoba Amarnath, A. Molinolo, Bidhan C. Bandyopadhyay +10 more
2007Arthritis & Rheumatism34 citations
Semantic Scholar
Advances in vector-mediated gene transfer.
B. Baum, C. Goldsmith, M. Kok, B. M. Lodde +5 more
2003Immunology Letters34 citations
Semantic Scholar
Adeno-Associated Virus Serotype 2-Mediated Gene Transfer to The Parotid Glands of Nonhuman Primates
A. Voutetakis, Chang-Yu Zheng, Fumi Mineshiba, Ana P. Cotrim +10 more
2007Human Gene Therapy29 citations
Semantic Scholar
AdLTR2EF1α-FGF2-mediated prevention of fractionated irradiation-induced salivary hypofunction in swine
L. Guo, Run-Tao Gao, Junji Xu, L. Jin +10 more
2014Gene Therapy28 citations
Semantic Scholar
Long-term transduction of miniature pig parotid glands using serotype 2 adeno-associated viral vectors
Hai Bo, Xing Yan, A. Voutetakis, Chang-Yu Zheng +10 more
2009Journal of Gene Medicine25 citations Open access
Semantic Scholar
Partial Redirection of Transgenic Human Growth Hormone Secretion from Rat Salivary Glands
Jiang-Huai Wang, N. Cawley, A. Voutetakis, Yazmin M. Rodriguez +7 more
2005Human Gene Therapy25 citations
Semantic Scholar
Adenoviral vector cytotoxicity depends in part on the transgene encoded.
Chengyu Zheng, C. Goldsmith, B. O'Connell, B. Baum
2000Biochemical and Biophysical Research Communications - BBRC24 citations
Semantic Scholar
Construction and in vivo efficacy of a replication-deficient recombinant adenovirus encoding murine growth hormone.
Yitzhak Marmary, A. F. Parlow, C. Goldsmith, Xin-Jun He +6 more
1999Endocrinology22 citations Open access
Semantic Scholar
Persistence of hAQP1 expression in human salivary gland cells following AdhAQP1 transduction is associated with a lack of methylation of hCMV promoter
Chang-Yu Zheng, Bruce J. Baum, Xi-Bao Liu, C. Goldsmith +6 more
2015Gene Therapy21 citations Open access
Semantic Scholar
Gender Differences in Serotype 2 Adeno-Associated Virus Biodistribution After Administration to Rodent Salivary Glands
A. Voutetakis, Chang-Yu Zheng, Jiang-Hua Wang, C. Goldsmith +6 more
2007Human Gene Therapy18 citations
Semantic Scholar
Toxicity and biodistribution of a first-generation recombinant adenoviral vector, in the presence of hydroxychloroquine, following retroductal delivery to a single rat submandibular gland.
C. Zheng, A. Voutetakis, M.-R. Kok, C. Goldsmith +6 more
2006Oral Diseases17 citations
Semantic Scholar
Using HSV-Thymidine Kinase for Safety in an Allogeneic Salivary Graft Cell Line
D. Aframian, Chang-Yu Zheng, C. Goldsmith, J. Nikolovski +5 more
2001Tissue engineering16 citations Open access
Semantic Scholar
Effect of Tempol on the prevention of irradiation-induced mucositis in miniature pigs
Liang Hu, Yijuan Wang, Ana P. Cotrim, Zhao Zhu +8 more
2017Oral Diseases15 citations Open access
Semantic Scholar
Expression of the aquaporin 8 water channel in a rat salivary epithelial cell line †
A. T. M. Shamsul Hoque, S. Yamano, Xi-Bao Liu, W. Swaim +3 more
2002Journal of Cellular Physiology15 citations
Semantic Scholar
Immune reactivity after adenoviral-mediated aquaporin-1 cDNA transfer to human parotid glands
I. Alevizos, Chang-Yu Zheng, Ana P. Cotrim, C. Goldsmith +10 more
2017Oral Diseases13 citations Open access
Semantic Scholar
Gene Therapy of Salivary Diseases
B. Baum, S. Afione, J. Chiorini, Ana P. Cotrim +2 more
2017Methods in molecular biology12 citations Open access
Semantic Scholar
Salivary glands as a model for craniofacial applications of gene transfer.
Bruce J. Baum, C. Goldsmith, A. T. M. Shamsul Hoque, R. Wellner +6 more
2000International Journal of Oral & Maxillofacial Surgery11 citations Open access
Semantic Scholar
Loss of Hs3st3a1 or Hs3st3b1 enzymes alters heparan sulfate to reduce epithelial morphogenesis and adult salivary gland function
V. Patel, Dallas L. Pineda, E. Berenstein, Belinda R. Hauser +10 more
2021Matrix Biology10 citations Open access
Semantic Scholar
Transgenic α-1-antitrypsin secreted into the bloodstream from salivary glands is biologically active
Paola Perez, J. Adriaansen, C. Goldsmith, Chang-Yu Zheng +1 more
2010Oral Diseases9 citations Open access
Semantic Scholar
A recombinant adenoviral vector encoding functional vasoactive intestinal peptide.
B. M. Lodde, C. Delporte, C. Goldsmith, P. Tak +1 more
2004Biochemical and Biophysical Research Communications - BBRC9 citations
Semantic Scholar
Association of G protein-coupled receptor 78 with salivary dysfunction in male Sjögren's patients.
Tsutomu Tanaka, M. C. Guimaro, Hiroyuki Nakamura, P. Pérez +8 more
2023Oral Diseases8 citations Open access
Semantic Scholar
Transient TWEAK overexpression leads to a general salivary epithelial cell proliferation
T. Sugito, Fumi Mineshiba, Chang-Yu Zheng, Ana P. Cotrim +2 more
2008Oral Diseases8 citations Open access
Semantic Scholar
Towards Gene Therapy for Growth Hormone Deficiency via Salivary Gland Expression of Growth Hormone
Gabor Z. Racz, Chang-Yu Zheng, C. Goldsmith, Bruce J. Baum +1 more
2014Oral Diseases7 citations Open access
Semantic Scholar
Gene therapy of salivary diseases.
B. Baum, J. Adriaansen, Ana P. Cotrim, C. Goldsmith +4 more
2010Methods in molecular biology3 citations Open access
Semantic Scholar
Erratum: STIM2 enhances receptor-stimulated Ca2+ signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions (Science Signaling 8:359 (ra3))
H. L. Ong, L. de Souza, Chang-Yu Zheng, Kwong-Tai Cheng +4 more
20152 citations
Semantic Scholar
Use of localized gene transfer to develop novel treatment strategies for the salivary component of Sjögren ' s syndrome
M. Kok, Chang-Yu Zheng, loannis Bossis, Jianghua Wang +6 more
20081 citations
Semantic Scholar
涎腺基因转导的临床应用
B. Baum, Chang-Yu Zheng, Llias Alevizos, Ana P. Cotrim +5 more
20090 citations
Semantic Scholar
Use of localized gene transfer to develop novel treatment strategies for the salivary component of Sjögren's syndrome
M. Kok, Chang-Yu Zheng, loannis Bossis, Jiang-Huai Wang +6 more
20080 citations
Semantic Scholar

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Chang-Yu Zheng×25
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B. Baum×20
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Ana P. Cotrim×18
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Bruce J. Baum×17
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Chang-Yu Zheng×9

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