S. Bournazos

Most-cited papers

The role of IgG Fc receptors in antibody-dependent enhancement
S. Bournazos, Aaron Gupta, J. Ravetch
2020Nature reviews. Immunology565 citations Open access
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HIV therapy by a combination of broadly neutralizing antibodies in humanized mice
F. Klein, Ariel Halper-Stromberg, J. Horwitz, H. Gruell +20 more
2012Nature530 citations Open access
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Broadly neutralizing anti-HIV-1 antibodies require Fc effector functions for in vivo activity
S. Bournazos, F. Klein, J. Pietzsch, M. Seaman +2 more
2014Cell510 citations Open access
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Type-I and Type-II Fc receptors regulate innate and adaptive immunity
Andrew Pincetic, S. Bournazos, D. DiLillo, Jad Maamary +4 more
2014Nature Immunology487 citations Open access
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Broadly Neutralizing Antibodies and Viral inducers decrease rebound from HIV-1 latent reservoirs in humanized mice
Ariel Halper-Stromberg, Ching-Lan Lu, F. Klein, J. Horwitz +12 more
2014Cell372 citations Open access
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IgG antibodies to dengue enhanced for FcγRIIIA binding determine disease severity
Taia T. Wang, Jaturong Sewatanon, Matthew J. Memoli, J. Wrammert +9 more
2017Science345 citations Open access
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Enhanced clearance of HIV-1-infected cells by anti-HIV-1 broadly neutralizing antibodies in vivo
Ching-Lan Lu, Dariusz K. Murakowski, S. Bournazos, T. Schoofs +10 more
2016Science338 citations Open access
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Mouse model recapitulating human Fcγ receptor structural and functional diversity
Patrick T. Smith, D. DiLillo, S. Bournazos, Fu-Bin Li +1 more
2012Proceedings of the National Academy of Sciences of the United States of America312 citations Open access
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Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo
A. Schäfer, Frauke Muecksch, Julio C. C. Lorenzi, S. Leist +14 more
2020Journal of Experimental Medicine302 citations Open access
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Modulating IgG effector function by Fc glycan engineering
Tiezheng Li, D. DiLillo, S. Bournazos, John P. Giddens +2 more
2017Proceedings of the National Academy of Sciences of the United States of America302 citations Open access
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Apoptotic human cells inhibit migration of granulocytes via release of lactoferrin.
Irini Bournazou, J. Pound, R. Duffin, S. Bournazos +4 more
2008Journal of Clinical Investigation238 citations Open access
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Signaling by Antibodies: Recent Progress
S. Bournazos, Taia T. Wang, R. Dahan, Jad Maamary +1 more
2017Annual Review of Immunology219 citations Open access
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Anti-HA glycoforms drive B cell affinity selection and determine influenza vaccine efficacy
Taia T. Wang, Jad Maamary, G. Tan, S. Bournazos +6 more
2015Cell200 citations Open access
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Fcγ Receptor Function and the Design of Vaccination Strategies
S. Bournazos, J. Ravetch
2017Immunity181 citations Open access
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Fc-engineered antibody therapeutics with improved anti-SARS-CoV-2 efficacy
Rachel Yamin, Andrew T Jones, H. Hoffmann, A. Schäfer +7 more
2021Nature173 citations Open access
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Functional and clinical consequences of Fc receptor polymorphic and copy number variants
S. Bournazos, J. Woof, S. Hart, I. Dransfield
2009Clinical and Experimental Immunology158 citations Open access
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The role of Fc–FcγR interactions in IgG-mediated microbial neutralization
S. Bournazos, D. DiLillo, J. Ravetch
2015Journal of Experimental Medicine155 citations Open access
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Fc-optimized antibodies elicit CD8 immunity to viral respiratory infection
S. Bournazos, D. Corti, H. Virgin, J. Ravetch
2020Nature142 citations Open access
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Bispecific anti-HIV-1 antibodies with enhanced breadth and potency
S. Bournazos, A. Gazumyan, M. Seaman, M. Nussenzweig +1 more
2016Cell142 citations Open access
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Glucocorticoids Induce Protein S-Dependent Phagocytosis of Apoptotic Neutrophils by Human Macrophages1
A. McColl, S. Bournazos, S. Franz, M. Perretti +3 more
2009Journal of Immunology141 citations
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Fcγ Receptor Pathways during Active and Passive Immunization
S. Bournazos, Jeffrey V. Ravetch
2015Immunological Reviews134 citations Open access
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Antibody fucosylation predicts disease severity in secondary dengue infection
S. Bournazos, H. T. M. Vo, V. Duong, H. Auerswald +5 more
2021Science121 citations Open access
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The Role and Function of Fcγ Receptors on Myeloid Cells
S. Bournazos, Taia T. Wang, J. Ravetch
2016Microbiology spectrum112 citations Open access
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Diversification of IgG effector functions
S. Bournazos, J. Ravetch
2017International Immunology106 citations Open access
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FcRn, but not FcγRs, drives maternal-fetal transplacental transport of human IgG antibodies
Sara Borghi, S. Bournazos, Natalie K. Thulin, Chao Li +8 more
2020Proceedings of the National Academy of Sciences of the United States of America92 citations Open access
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A mouse model for HIV-1 entry
J. Pietzsch, H. Gruell, S. Bournazos, B. M. Donovan +7 more
2012Proceedings of the National Academy of Sciences of the United States of America76 citations Open access
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PD-1 directed immunotherapy alters Tfh and humoral immune responses to seasonal influenza vaccine
R. Herati, D. Knorr, Laura A. Vella, L. Silva +24 more
2022Nature Immunology75 citations Open access
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A Combination of Two Human Monoclonal Antibodies Prevents Zika Virus Escape Mutations in Non-human Primates
J. Keeffe, K. V. Van Rompay, P. Olsen, Qiao Wang +20 more
2018Cell Reports69 citations Open access
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Maternal Anti-Dengue IgG Fucosylation Predicts Susceptibility to Dengue Disease in Infants
Natalie K. Thulin, R. C. Brewer, R. Sherwood, S. Bournazos +9 more
2020Cell Reports63 citations Open access
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Human IgG Fc domain engineering enhances antitoxin neutralizing antibody activity.
S. Bournazos, Siu-Kei Chow, Nareen Abboud, A. Casadevall +1 more
2014Journal of Clinical Investigation62 citations Open access
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Monocyte Functional Responsiveness After PSGL-1–Mediated Platelet Adhesion Is Dependent on Platelet Activation Status
S. Bournazos, J. Rennie, S. Hart, K. Fox +1 more
2008Arteriosclerosis, Thrombosis and Vascular Biology62 citations Open access
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Anti-Retroviral Antibody FcγR-mediated Effector Functions
S. Bournazos, Jeffrey V. Ravetch
2017Immunological Reviews54 citations Open access
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Differential requirements for FcγR engagement by protective antibodies against Ebola virus
S. Bournazos, D. DiLillo, A. Goff, P. Glass +1 more
2019Proceedings of the National Academy of Sciences of the United States of America52 citations Open access
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Antibodies targeting sialyl Lewis A mediate tumor clearance through distinct effector pathways.
Polina Weitzenfeld, S. Bournazos, J. Ravetch
2019Journal of Clinical Investigation47 citations Open access
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Association of FcγRIIa (CD32a) with Lipid Rafts Regulates Ligand Binding Activity1
S. Bournazos, S. Hart, L. Chamberlain, M. Glennie +1 more
2009Journal of Immunology44 citations Open access
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Beyond Viral Neutralization
G. Lewis, M. Pazgier, David T. Evans, G. Ferrari +4 more
2017AIDS Research and Human Retroviruses40 citations Open access
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Choice of anticoagulant critically affects measurement of circulating platelet-leukocyte complexes.
S. Bournazos, J. Rennie, S. Hart, I. Dransfield
2007Arteriosclerosis, Thrombosis and Vascular Biology36 citations Open access
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Site-Selective Chemoenzymatic Modification on the Core Fucose of an Antibody Enhances Its Fcγ Receptor Affinity and ADCC Activity
Chao Li, Ge-Ne Chong, Guang-Hui Zong, D. Knorr +6 more
2021Journal of the American Chemical Society35 citations Open access
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humanized mice to study FcγR function.
S. Bournazos, D. DiLillo, J. Ravetch
2014Current Topics in Microbiology and Immunology35 citations
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Human FcγRIIIa activation on splenic macrophages drives dengue pathogenesis in mice
Rachel Yamin, Kevin Kao, M. MacDonald, T. Cantaert +3 more
2023Nature Microbiology34 citations Open access
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Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection in vivo
A. Schäfer, Frauke Muecksch, Julio C. C. Lorenzi, S. Leist +11 more
2020bioRxiv34 citations Open access
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A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques
K. V. Van Rompay, L. Coffey, Tania Kapoor, A. Gazumyan +22 more
2020Proceedings of the National Academy of Sciences of the United States of America34 citations Open access
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Lysibodies are IgG Fc fusions with lysin binding domains targeting Staphylococcus aureus wall carbohydrates for effective phagocytosis
Assaf Raz, A. Serrano, C. Lawson, Maneesha Thaker +4 more
2017Proceedings of the National Academy of Sciences of the United States of America32 citations Open access
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IgG Fc Receptors: Evolutionary Considerations.
S. Bournazos
2019Current Topics in Microbiology and Immunology29 citations
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One-Pot Conversion of Free Sialoglycans to Functionalized Glycan Oxazolines and Efficient Synthesis of Homogeneous Antibody–Drug Conjugates through Site-Specific Chemoenzymatic Glycan Remodeling
Chong Ou, Chao Li, Roushu Zhang, Qiang Yang +6 more
2021Bioconjugate chemistry28 citations Open access
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Fc‐FcγR interactions during infections: From neutralizing antibodies to antibody‐dependent enhancement
Julia E. Edgar, S. Bournazos
2024Immunological Reviews27 citations Open access
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Internalization of secreted antigen–targeted antibodies by the neonatal Fc receptor for precision imaging of the androgen receptor axis
D. Thorek, Philip A Watson, Sang-gyu Lee, Anson T. Ku +20 more
2016Science Translational Medicine27 citations Open access
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Antibody and Antiretroviral Preexposure Prophylaxis Prevent Cervicovaginal HIV-1 Infection in a Transgenic Mouse Model
H. Gruell, S. Bournazos, J. Ravetch, A. Ploss +2 more
2013Journal of Virology26 citations Open access
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Immunological responses to influenza vaccination: lessons for improving vaccine efficacy
Taia T. Wang, S. Bournazos, J. Ravetch
2018Current Opinion in Immunology24 citations Open access
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Copy Number Variation of FCGR3B Is Associated with Susceptibility to Idiopathic Pulmonary Fibrosis
S. Bournazos, Irini Bournazou, J. Murchison, W. Wallace +5 more
2010Respiration24 citations Open access
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