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Theresa M. Keeley · SciRah

Researcher profile · Semantic Scholar

Theresa M. Keeley

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Theresa M. Keeley — researcher profile on SciRah

h-index: 20
Works: 55
Citations: 1,928

Most-cited papers

Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells
K. VanDussen, A. Carulli, Theresa M. Keeley, Sanjeevkumar R. Patel +12 more
2012Development567 citations Open access
Semantic Scholar
Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration
A. Carulli, Theresa M. Keeley, E. Demitrack, J. Chung +2 more
2015Developmental Biology137 citations Open access
Semantic Scholar
Gastric Tuft Cells Express DCLK1, and Increase in Hyperplasia
M. Saqui-Salces, Theresa M. Keeley, Ann S. Grosse, Xiao-Tan T. Qiao +4 more
2011Histochemistry and Cell Biology116 citations Open access
Semantic Scholar
Notch signaling regulates gastric antral LGR5 stem cell function
E. Demitrack, Gail B. Gifford, Theresa M. Keeley, A. Carulli +6 more
2015EMBO Journal97 citations Open access
Semantic Scholar
Notch and mTOR Signaling Pathways Promote Human Gastric Cancer Cell Proliferation
Elise S. Hibdon, Nataliya Razumilava, Theresa M. Keeley, G. Wong +3 more
2019Neoplasia81 citations Open access
Semantic Scholar
Intestinal Neurogenin 3 directs differentiation of a bipotential secretory progenitor to endocrine cell rather than goblet cell fate.
L. López-Díaz, Renu Jain, Theresa M. Keeley, K. VanDussen +3 more
2007Developmental Biology81 citations Open access
Semantic Scholar
The PIAS-like coactivator Zmiz1 is a direct and selective cofactor of Notch1 in T-cell development and leukemia
N. Pinnell, Ran Yan, H. Cho, Theresa M. Keeley +11 more
2015Immunity77 citations Open access
Semantic Scholar
Bone Morphogenetic Protein Signaling Regulates Gastric Epithelial Cell Development and Proliferation in Mice
M. Shinohara, Maria Y. Mao, Theresa M. Keeley, M. El-zaatari +6 more
2010Gastroenterology73 citations Open access
Semantic Scholar
Hip1r is expressed in gastric parietal cells and is required for tubulovesicle formation and cell survival in mice.
Renu Jain, Asma A. Al-Menhali, Theresa M. Keeley, Jianhua Ren +6 more
2008Journal of Clinical Investigation66 citations Open access
Semantic Scholar
Lrig1+ gastric isthmal progenitor cells restore normal gastric lineage cells during damage recovery in adult mouse stomach
Eunyoung Choi, Tyler L. Lantz, G. Vlacich, Theresa M. Keeley +4 more
2017Gut61 citations Open access
Semantic Scholar
Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis
Gail B. Gifford, E. Demitrack, Theresa M. Keeley, Andrew Tam +8 more
2016Gut61 citations Open access
Semantic Scholar
Cytodifferentiation of the postnatal mouse stomach in normal and Huntingtin-interacting protein 1-related-deficient mice.
Theresa M. Keeley, L. Samuelson
2010American Journal of Physiology - Gastrointestinal and Liver Physiology55 citations Open access
Semantic Scholar
Gastrointestinal , Hepatobiliary , and Pancreatic Pathology Transgenic Expression of Interferon-in Mouse Stomach Leads to Inflammation , Metaplasia , and Dysplasia
L. Syu, M. El-zaatari, K. Eaton, Zhiping Liu +13 more
201252 citations
Semantic Scholar
Gastric acid secretion from parietal cells is mediated by a Ca2+ efflux channel in the tubulovesicle
N. Sahoo, Mingxue Gu, Xiao-Li Zhang, N. Raval +17 more
2017Developmental Cell51 citations Open access
Semantic Scholar
NOTCH1 and NOTCH2 regulate epithelial cell proliferation in mouse and human gastric corpus.
Elise S. Demitrack, Gail B. Gifford, Theresa M. Keeley, Nobukatsu Horita +4 more
2017American Journal of Physiology - Gastrointestinal and Liver Physiology49 citations Open access
Semantic Scholar
Parietal cell hyperstimulation and autoimmune gastritis in cholera toxin transgenic mice.
L. López-Díaz, Karen L. Hinkle, Renu Jain, Y. Zavros +6 more
2006American Journal of Physiology - Gastrointestinal and Liver Physiology49 citations
Semantic Scholar
Tamoxifen-Induced Gastric Injury: Effects of Dose and Method of Administration
Theresa M. Keeley, Nobukatsu Horita, L. Samuelson
2019Cellular and Molecular Gastroenterology and Hepatology39 citations Open access
Semantic Scholar
Insulin-like Growth Factor-1 and mTORC1 Signaling Promote the Intestinal Regenerative Response After Irradiation Injury
Natacha Bohin, Kevin P. McGowan, Theresa M. Keeley, Elizabeth A. Carlson +2 more
2020Cellular and Molecular Gastroenterology and Hepatology37 citations Open access
Semantic Scholar
Rapid Crypt Cell Remodeling Regenerates the Intestinal Stem Cell Niche after Notch Inhibition
Natacha Bohin, Theresa M. Keeley, A. Carulli, E. Walker +10 more
2020Stem Cell Reports33 citations Open access
Semantic Scholar
IFNγ contributes to the development of gastric epithelial cell metaplasia in Huntingtin Interacting Protein 1 related (Hip1r)-deficient mice
Zhiping Liu, E. Demitrack, Theresa M. Keeley, K. Eaton +3 more
2012Laboratory Investigation22 citations Open access
Semantic Scholar
Combinatorial ETS1-dependent control of oncogenic NOTCH1 enhancers in T-cell leukemia
Anna C. McCarter, Giusy Della Gatta, Ashley F Melnick, Erin Kim +18 more
2020Blood Cancer Discovery19 citations Open access
Semantic Scholar
Gastrin induces parathyroid hormone-like hormone expression in gastric parietal cells.
Asma Al Menhali, Theresa M. Keeley, E. Demitrack, L. Samuelson
2017American Journal of Physiology - Gastrointestinal and Liver Physiology18 citations Open access
Semantic Scholar
Epithelial Regeneration After Doxorubicin Arises Primarily From Early Progeny of Active Intestinal Stem Cells
B. Sheahan, Ally N. Freeman, Theresa M. Keeley, L. Samuelson +4 more
2021Cellular and Molecular Gastroenterology and Hepatology17 citations Open access
Semantic Scholar
Delta-like 1–Expressing Cells at the Gland Base Promote Proliferation of Gastric Antral Stem Cells in Mouse
Nobukatsu Horita, Theresa M. Keeley, Elise S. Hibdon, Elizabeth Delgado +3 more
2021Cellular and Molecular Gastroenterology and Hepatology16 citations Open access
Semantic Scholar
Regulation of gastric epithelial cell homeostasis by gastrin and bone morphogenetic protein signaling
A. Todisco, Maria Y. Mao, Theresa M. Keeley, Wei-Xia Ye +2 more
2011Physiological Reports16 citations Open access
Semantic Scholar
C‐X‐C motif chemokine ligand 1 induced by Hedgehog signaling promotes mouse extrahepatic bile duct repair after acute injury
Nureen H. Mohamad Zaki, Junya Shiota, Ashley N. Calder, Theresa M. Keeley +4 more
2022Hepatology11 citations Open access
Semantic Scholar
Dietary iron is necessary to support proliferative regeneration following intestinal injury.
Wesley Huang, Nupur K. Das, Megan D. Radyk, Theresa M. Keeley +9 more
2024Journal of NutriLife8 citations Open access
Semantic Scholar
Notch signaling modulates proliferation and differentiation of intestinal crypt base columnar stem cells
K. VanDussen, A. Carulli, Theresa M. Keeley, Sanjeevkumar R. Patel +12 more
7 citations
Semantic Scholar
Region-specific Wnt signaling responses promote gastric polyp formation in patients with familial adenomatous polyposis
Kevin P. McGowan, Elizabeth Delgado, Theresa M. Keeley, Elise S. Hibdon +3 more
2023JCI Insight6 citations Open access
Semantic Scholar
The bHLH Transcription Factor ASCL1 Promotes Differentiation of Endocrine Cells in the Stomach and is Regulated by Notch Signaling.
Elise S. Hibdon, Theresa M. Keeley, J. Merchant, L. Samuelson
2023American Journal of Physiology - Gastrointestinal and Liver Physiology6 citations
Semantic Scholar
WNT signaling contributes to the extrahepatic bile duct proliferative response to obstruction in mice
Ashley N Calder, Mirabelle Peter, John W. Tobias, Nureen H. Mohamad Zaki +4 more
2024JCI Insight2 citations Open access
Semantic Scholar
Hypergastrinemia and hypertrophic gastritis in Hip1r‐deficient mice
Renu Jain, Asma Al Menhali, Theresa M. Keeley, T. S. Ross +2 more
20072 citations
Semantic Scholar
The hematopoietic stem cell MYB enhancer is essential for and recurrently amplified during T cell leukemogenesis
Carea Mullin, Karena Lin, Elizabeth Choe, Cher Sha +29 more
2025Journal of Clinical Investigation1 citations
Semantic Scholar
Paneth cell-derived Notch ligands DLL1 and DLL4 are crucial for intestinal crypt base stem cells
Michaela Quintero, Theresa M. Keeley, Justin A. Colacino, Nan Gao +2 more
2026bioRxiv0 citations Open access
Semantic Scholar
Wnt Regulates Cellular Differentiation and Retinoid Metabolism Genes in the Mouse Stomach
Elizabeth Delgado, Elise S. Hibdon, Theresa M. Keeley, C. Huynh +2 more
2026American Journal of Physiology - Gastrointestinal and Liver Physiology0 citations Open access
Semantic Scholar
Wnt signaling promotes gastric chief cell identity and mucosal repair after injury
C. Huynh, Theresa M. Keeley, Eunyoung Choi, Linda C. Samuelson
2026Physiology0 citations
Semantic Scholar
Intestinal crypts remodel in response to deletion of Notch pathway ligands from Paneth cells
Michaela Quintero, Theresa M. Keeley, Nan Gao, Peter J. Dempsey +1 more
2025Physiology0 citations
Semantic Scholar
Intestinal Stem Cells Remodel in Response to Acute Notch Inhibition and Paneth Cell Loss
Michaela Quintero, Theresa M. Keeley, J. Colacino, Anagha Tapaswi +1 more
2024Physiology0 citations
Semantic Scholar
High levels of Wnt signaling reduce proliferation and promote deep glandular differentiation in human gastric corpus-derived organoids
Kevin P. McGowan, Elizabeth Delgado, Elise S. Hibdon, Theresa M. Keeley +1 more
2023Physiology0 citations
Semantic Scholar
Distinct Wnt Signaling Thresholds Required for Polyposis in the Proximal and Distal Stomach
Elizabeth Delgado, Theresa M. Keeley, Elise S. Hibdon, Kevin P. McGowan +4 more
2022The FASEB Journal0 citations
Semantic Scholar
IGF1‐mTORC1 Signaling Drives Intestinal Epithelial Regeneration After Irradiation Injury
Yasmine Abushukur, Natacha Bohin, Kevin P. McGowan, Theresa M. Keeley +2 more
2019The FASEB Journal0 citations
Semantic Scholar
Rapid crypt cell remodeling regenerates the intestinal stem cell niche after stem cell loss induced by Notch inhibition
Natacha Bohin, Theresa M. Keeley, Alexis J. Carulli, Elizabeth A. Carlson +8 more
20180 citations
Semantic Scholar
806 Notch Pathway Regulation of Intestinal Stem Cell Self-Renewal
A. Carulli, Theresa M. Keeley, S. Schnell, L. Samuelson
20160 citations
Semantic Scholar
Identification of novel gastric stem cell markers and investigation of Intestinal Stem Cell Cre-mediated Recombination
Theresa M. Keeley
20150 citations
Semantic Scholar
Direct Coregulation of Notch1 By Zmiz1 in T-Cell Development and Leukemia
N. Pinnell, Ran Yan, H. Cho, Paula Jeon +8 more
20140 citations
Semantic Scholar
260 Notch Regulation of LGR5+ Stem Cells in the Gastric Antrum
E. Demitrack, Theresa M. Keeley, L. Samuelson
20120 citations
Semantic Scholar
Notch signaling regulates proliferation and differentiation of the intestinal crypt base columnar (CBC) stem cell
L. Samuelson, Kelli L. VanDussen, Alexis J. Carulli, Theresa M. Keeley +1 more
20120 citations
Semantic Scholar
Gastro-Intestinal Tuft Cells Are DCLK1 Positive, and Appear Late in Development
M. Saqui-Salces, Theresa M. Keeley, L. Samuelson, D. Gumucio +1 more
20110 citations Open access
Semantic Scholar
673 Anti-Inflammatory Actions of BMP Signaling in the Stomach
A. Todisco, M. Shinohara, Maria Y. Mao, Theresa M. Keeley +2 more
20100 citations Open access
Semantic Scholar
672 The Role of Inflammatory Mediators for Progressive Gastric Epithelial Cell Transformation in Hip1r-Deficient Mice
Zhiping Liu, Theresa M. Keeley, K. Eaton, L. Samuelson
20100 citations Open access
Semantic Scholar

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L. Samuelson — researcher profile on SciRah
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