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M. Brennan · SciRah

Researcher profile · Semantic Scholar

M. Brennan

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M. Brennan — researcher profile on SciRah

h-index: 11
Works: 31
Citations: 1,749

Most-cited papers

Integrins as therapeutic targets: lessons and opportunities
D. Cox, M. Brennan, N. Moran
2010Nature reviews. Drug discovery460 citations Open access
Semantic Scholar
Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond
W. Van Voorhis, J. Adams, R. Adelfio, V. Ahyong +183 more
2016PLoS Pathogens364 citations Open access
Semantic Scholar
Fibronectin‐binding proteins of Staphylococcus aureus mediate activation of human platelets via fibrinogen and fibronectin bridges to integrin GPIIb/IIIa and IgG binding to the FcγRIIa receptor
J. R. Fitzgerald, Anthony Loughman, F. M. Keane, M. Brennan +6 more
2006Molecular Microbiology210 citations Open access
Semantic Scholar
Roles for fibrinogen, immunoglobulin and complement in platelet activation promoted by Staphylococcus aureus clumping factor A
Anthony Loughman, J. R. Fitzgerald, M. Brennan, Judy Higgins +3 more
2005Molecular Microbiology197 citations Open access
Semantic Scholar
Fibrinogen and elastin bind to the same region within the A domain of fibronectin binding protein A, an MSCRAMM of Staphylococcus aureus
F. M. Keane, Anthony Loughman, V. Valtulina, M. Brennan +2 more
2007Molecular Microbiology123 citations Open access
Semantic Scholar
Molecular interactions and inhibition of the staphylococcal biofilm-forming protein SdrC
C. Feuillie, C. Formosa-Dague, L. Hays, Ophélie Vervaeck +5 more
2017Proceedings of the National Academy of Sciences of the United States of America93 citations Open access
Semantic Scholar
Elucidating the role of Staphylococcus epidermidis serine–aspartate repeat protein G in platelet activation
M. Brennan, Anthony Loughman, M. Devocelle, S. Arasu +3 more
2009Journal of Thrombosis and Haemostasis86 citations Open access
Semantic Scholar
Both Complement- and Fibrinogen-Dependent Mechanisms Contribute to Platelet Aggregation Mediated by Staphylococcus aureus Clumping Factor B
Helen Miajlović, Anthony Loughman, M. Brennan, D. Cox +1 more
2007Infection and Immunity81 citations Open access
Semantic Scholar
E-publications@rcsi Citation Attribution-non-commercial-sharealike 1.0 a Novel Platinum Complex of the Histone Deacetylase Inhibitor Belinostat; Rational Design, Development and in Vitro Cytotoxicity
James P. Parker, Hassan I. Nimir, D. Griffith, B. Duff +18 more
28 citations
Semantic Scholar
C‐reactive protein binds to αIIbβ3
M. Brennan, R. Moriarty, S. Grennan, A. Chubb +1 more
2008Journal of Thrombosis and Haemostasis15 citations Open access
Semantic Scholar
In Vitro Activities of Synthetic Host Defense Propeptides Processed by Neutrophil Elastase against Cystic Fibrosis Pathogens
Stéphane Desgranges, Florie Le Prieult, Alan Daly, J. Lydon +11 more
2011Antimicrobial Agents and Chemotherapy14 citations Open access
Semantic Scholar
Functional Antagonism of Junctional Adhesion Molecule-A (JAM-A), Overexpressed in Breast Ductal Carcinoma In Situ (DCIS), Reduces HER2-Positive Tumor Progression
Y. Smith, Guannan Wang, Ciara L. Flynn, S. Madden +19 more
2022Cancers10 citations Open access
Semantic Scholar
A novel role for the fibrinogen Asn-Gly-Arg (NGR) motif in platelet function
R. Moriarty, C. McManus, M. Lambert, T. Tilley +4 more
2014Thrombosis and Haemostasis10 citations Open access
Semantic Scholar
TIN - A Combinatorial Compound Collection of Synthetically Feasible Multicomponent Synthesis Products
Kristl V. Dorschner, David Toomey, M. Brennan, T. Heinemann +5 more
2011Journal of Chemical Information and Modeling10 citations Open access
Semantic Scholar
Multi-Targeted Metallo-Ciprofloxacin Derivatives Rationally Designed and Developed to Overcome Antimicrobial Resistance.
Ziga Ude, Nils Flothkötter, G. Sheehan, M. Brennan +2 more
2021International Journal of Antimicrobial Agents9 citations Open access
Semantic Scholar
Allantodapsone is a Pan-Inhibitor of Staphylococcus aureus Adhesion to Fibrinogen, Loricrin, and Cytokeratin 10
Filippo Prencipe, Aishah M. Alsibaee, Zainab Khaddem, P. Norton +8 more
2022Microbiology spectrum8 citations Open access
Semantic Scholar
Impact of genetic variation in the 5-HT transporter and receptor on platelet function in patients with stable CAD taking aspirin.
A. Bajrangee, N. Ryan, C. Vangjeli, M. Brennan +4 more
2016Thrombosis Research8 citations
Semantic Scholar
Genomes2Drugs: Identifies Target Proteins and Lead Drugs from Proteome Data
David Toomey, H. Hoppe, M. Brennan, K. B. Nolan +1 more
2009PLoS ONE8 citations Open access
Semantic Scholar
The therapeutic potential of I-domain integrins.
M. Brennan, D. Cox
2014Advances in Experimental Medicine and Biology7 citations
Semantic Scholar
Peptide Diversity in Drug Discovery
M. Brennan, D. Cox, A. Chubb
20075 citations
Semantic Scholar
Novel anti‐staphylococcal and anti‐biofilm properties of two anti‐malarial compounds: MMV665953 {1‐(3‐chloro‐4‐fluorophenyl)‐3‐(3,4‐dichlorophenyl)urea} and MMV665807 {5‐chloro‐2‐hydroxy‐N‐[3‐(trifluoromethyl)phenyl]benzamide}
M. Zapotoczna, Nabila Boksmati, S. Donohue, Baizurina Bahtiar +7 more
2017Journal of Medical Microbiology4 citations Open access
Semantic Scholar
Deadly Engagement: FcγRIIa-Antibody Interaction is Key in Sepsis.
M. Brennan
2016TIPS - Trends in Pharmacological Sciences1 citations
Semantic Scholar
Use of Xpert MRSA/SA BC for direct testing on breast milk from women with mastitis: a diagnostic accuracy study
N. Cahill, H. Hammerton, C. O’Connor, M. Brennan +2 more
20180 citations Open access
Semantic Scholar
47 Novel inflammatory biomarkers of coronary plaque instability and rupture
A. Bajrangee, S. Mahabir, M. Brennan, Dermot Cox +1 more
2017Heart0 citations
Semantic Scholar
62 Galectin-3 as a marker of unstable coronary plaque
A. Bajrangee, L. Arkins, M. Brennan, Dermot Cox +1 more
2017Heart0 citations
Semantic Scholar
Abstract 18948: Galectin-3 as a Novel Biomarker of Unstable Coronary Plaque
A. Bajrangee, S. Mahabir, L. Arkins, C. O'Connor +4 more
20160 citations
Semantic Scholar
Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond Citation
W. Van Voorhis, J. Adams, R. Adelfio, V. Ahyong +182 more
20160 citations
Semantic Scholar
C-reactive protein binds to alphaIIbbeta 3
M. Brennan, R. Moriarty, S. Grennan, A. Chubb +1 more
20150 citations
Semantic Scholar
Characterization of the Mechanism of Interaction between C-Reactive Protein and GPIIb/IIIa.
M. Brennan, R. Moriarty, S. Arasu, T. Foster +1 more
20060 citations
Semantic Scholar
Abstract 635: Inhibition of Platelet Aggregation by C-Reactive Protein is Mediated by an Interaction with GPIIb/IIIa
M. Brennan, R. Moriarty, G. Meade, Grennan Sheelagh +2 more
20060 citations
Semantic Scholar
Staphylococcus Epidermidis Induced Platelet Aggregation Is Mediated by the Fibrinogen Binding Surface Protein SdrG.
M. Brennan, M. Devocelle, T. Foster, D. Cox
20040 citations
Semantic Scholar

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W. Van Voorhis — researcher profile on SciRah