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H. Asou · SciRah

Researcher profile · Semantic Scholar

H. Asou

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H. Asou — researcher profile on SciRah

h-index: 31
Works: 94
Citations: 4,156

Most-cited papers

Ligand for peroxisome proliferator-activated receptor gamma (troglitazone) has potent antitumor effect against human prostate cancer both in vitro and in vivo.
T. Kubota, K. Koshizuka, E. Williamson, H. Asou +4 more
1998Cancer Research649 citations
Semantic Scholar
Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein alpha in myelodysplastic syndromes and acute myeloid leukemias.
A. Gombart, W. Hofmann, S. Kawano, S. Takeuchi +7 more
2002Blood315 citations
Semantic Scholar
Establishment of a human acute myeloid leukemia cell line (Kasumi-1) with 8;21 chromosome translocation.
H. Asou, S. Tashiro, K. Hamamoto, A. Otsuji +2 more
1991Blood312 citations Open access
Semantic Scholar
Primary effusion lymphoma in women: report of two cases of Kaposi's sarcoma herpes virus-associated effusion-based lymphoma in human immunodeficiency virus-negative women.
Jonathan W. Said, T. Tasaka, S. Takeuchi, H. Asou +4 more
1996Blood228 citations Open access
Semantic Scholar
Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation.
Seiji Kawano, C. Miller, A. Gombart, C. Bartram +6 more
1999Blood191 citations
Semantic Scholar
Kaposi's sarcoma-associated herpesvirus (KSHV or HHV8) in primary effusion lymphoma: ultrastructural demonstration of herpesvirus in lymphoma cells.
W. Said, Kenneth R. Chien, S. Takeuchi, T. Tasaka +6 more
1996Blood182 citations Open access
Semantic Scholar
Localization of Kaposi's sarcoma-associated herpesvirus in bone marrow biopsy samples from patients with multiple myeloma.
Jonathan W. Said, M. Rettig, K. Heppner, R. Vescio +12 more
1997Blood176 citations Open access
Semantic Scholar
Identification of a breakpoint cluster region 3' of the ribophorin I gene at 3q21 associated with the transcriptional activation of the EVI1 gene in acute myelogenous leukemias with inv(3)(q21q26).
K. Suzukawa, E. Parganas, A. Gajjar, Tsukasa Abe +6 more
1994Blood162 citations Open access
Semantic Scholar
Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7.
Akiko Nagamachi, H. Matsui, H. Asou, Y. Ozaki +8 more
2013Cancer Cell140 citations Open access
Semantic Scholar
Junctions of the AML1/MTG8(ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction.
T. Kozu, H. Miyoshi, K. Shimizu, N. Maseki +4 more
1993Blood138 citations
Semantic Scholar
Mechanisms of growth control of Kaposi's sarcoma-associated herpes virus-associated primary effusion lymphoma cells.
H. Asou, J. Said, Rong Yang, R. Munker +3 more
1998Blood116 citations Open access
Semantic Scholar
Cytokines direct the regulation of Bim mRNA stability by heat-shock cognate protein 70.
H. Matsui, H. Asou, T. Inaba
2007Molecules and Cells115 citations Open access
Semantic Scholar
Phase 1 study of galunisertib, a TGF-beta receptor I kinase inhibitor, in Japanese patients with advanced solid tumors
Y. Fujiwara, H. Nokihara, Yasuhide Yamada, N. Yamamoto +7 more
2015Cancer Chemotherapy and Pharmacology87 citations
Semantic Scholar
Growth inhibition of myeloid leukemia cells by troglitazone, a ligand for peroxisome proliferator activated receptor gamma, and retinoids.
H. Asou, W. Verbeek, E. Williamson, E. Elstner +3 more
1999International Journal of Oncology77 citations
Semantic Scholar
Herpesvirus 8 inclusions in primary effusion lymphoma: report of a unique case with T-cell phenotype.
J. Said, I. Shintaku, H. Asou, S. deVos +5 more
1999Archives of Pathology & Laboratory Medicine76 citations
Semantic Scholar
Identification of a common microdeletion cluster in 7q21.3 subband among patients with myeloid leukemia and myelodysplastic syndrome.
H. Asou, H. Matsui, Y. Ozaki, Akiko Nagamachi +3 more
2009Biochemical and Biophysical Research Communications - BBRC75 citations Open access
Semantic Scholar
Combined effect of vitamin D3 analogs and paclitaxel on the growth of MCF-7 breast cancer cells in vivo
K. Koshizuka, M. Koike, H. Asou, Steve K. Cho +5 more
2004Breast Cancer Research and Treatment70 citations
Semantic Scholar
Establishment and characterization of a novel acute promyelocytic leukemia cell line (UF-1) with retinoic acid-resistant features.
M. Kizaki, H. Matsushita, Nobuyuki Takayama, A. Muto +6 more
1996Blood67 citations
Semantic Scholar
Poly-ADP ribosylation of Miki by tankyrase-1 promotes centrosome maturation.
Y. Ozaki, H. Matsui, H. Asou, Akiko Nagamachi +8 more
2012Molecules and Cells64 citations Open access
Semantic Scholar
19-nor vitamin-D analogs: a new class of potent inhibitors of proliferation and inducers of differentiation of human myeloid leukemia cell lines.
H. Asou, M. Koike, E. Elstner, Moray Cambell +4 more
1998Blood59 citations
Semantic Scholar
Methylation of the p16INK4A gene in multiple myeloma
T. Tasaka, H. Asou, R. Munker, Jonathan Said +5 more
1998British Journal of Haematology57 citations Open access
Semantic Scholar
Phase 1 study of abemaciclib, an inhibitor of CDK 4 and 6, as a single agent for Japanese patients with advanced cancer
Y. Fujiwara, K. Tamura, S. Kondo, Y. Tanabe +9 more
2016Cancer Chemotherapy and Pharmacology56 citations
Semantic Scholar
A Phase I study to assess the safety, pharmacokinetics and efficacy of barasertib (AZD1152), an Aurora B kinase inhibitor, in Japanese patients with advanced acute myeloid leukemia.
Kosuke Tsuboi, T. Yokozawa, T. Sakura, Takashi Watanabe +9 more
2011Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis54 citations
Semantic Scholar
Resveratrol, a Natural Product Derived from Grapes, Is a New Inducer of Differentiation in Human Myeloid Leukemias
H. Asou, K. Koshizuka, T. Kyo, N. Takata +2 more
2002International journal of hematology52 citations
Semantic Scholar
19-nor-hexafluoride analogue of vitamin D3: a novel class of potent inhibitors of proliferation of human breast cell lines.
M. Koike, E. Elstner, Moray J. Campbell, H. Asou +3 more
1997Cancer Research51 citations
Semantic Scholar
Identification of two transcripts of AMLI/ETO‐fused gene in t(8;21) leukemic cells and expression of wild‐type ETO gene in hematopoietic cells
T. Era, N. Asou, T. Kunisada, H. Yamasaki +5 more
1995Genes, Chromosomes and Cancer42 citations
Semantic Scholar
Establishment of the acute myeloid leukemia cell line Kasumi‐6 from a patient with a dominant‐negative mutation in the DNA‐binding region of the C/EBPα gene
H. Asou, A. Gombart, S. Takeuchi, Hideo Tanaka +5 more
2003Genes, Chromosomes and Cancer40 citations
Semantic Scholar
Establishment of an Undifferentiated Leukemia Cell Line (Kasumi‐3) with t(3;7)(q27;q22) and Activation of the EVI1 Gene
H. Asou, K. Suzukawa, K. Kita, K. Nakase +3 more
1996Japanese journal of cancer research : Gann40 citations Open access
Semantic Scholar
Mutations in the gene encoding the transcription factor CCAAT / enhancer binding protein a in myelodysplastic syndromes and acute myeloid leukemias
A. Gombart, Wolf-K. Hofmann, Seiji Kawano, Seisho Takeuchi +7 more
200239 citations
Semantic Scholar
Independent clones of trisomy 12 and retinoblastoma gene deletion in Japanese B cell chronic lymphocytic leukemia, detected by fluorescence in situ hybridization.
M. Arif, Kohji Tanaka, H. Asou, R. Ohno +1 more
1995Leukemia39 citations
Semantic Scholar
Cytogenetic 2; 18 and 18; 22 translocation in chronic lymphocytic leukemia with juxtaposition of bcl-2 and immunoglobulin light chain genes.
Satoshi Tashiro, M. Takechi, H. Asou, K. Takauchi +5 more
1992Oncogene37 citations
Semantic Scholar
Japanese B cell chronic lymphocytic leukaemia: a cytogenetic and molecular biological study
H. Asou, M. Takechi, Kimio J. Tanaka, S. Tashiro +3 more
1993British Journal of Haematology31 citations
Semantic Scholar
Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma
Lin-Hua Jin, Y. Tabe, S. Kimura, Yi-Xin Zhou +6 more
2010British Journal of Cancer30 citations Open access
Semantic Scholar
Hidden monosomy 7 in acute myeloid leukemia and myelodysplastic syndrome detected by interphase fluorescence in situ hybridization.
M. Arif, Kimio Tanaka, Chendil Damodaran, H. Asou +3 more
1996Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis29 citations
Semantic Scholar
Characteristics of interstitial lung disease in patients from post-marketing data on metastatic breast cancer patients who received abemaciclib in Japan
Yucherng Chen, S. Noma, Y. Taguchi, Masashi Takahashi +5 more
2021Breast Cancer24 citations Open access
Semantic Scholar
A phase 1 study of crenigacestat (LY3039478), the Notch inhibitor, in Japanese patients with advanced solid tumors
T. Doi, M. Tajimi, J. Mori, H. Asou +3 more
2020Investigational new drugs21 citations Open access
Semantic Scholar
A specific chromosome abnormality of t(4;12)(qll‐12;pl3) in CD7+ acute leukaemia
Hironort Harada, H. Asou, T. Kyo, H. Asaoku +6 more
1995British Journal of Haematology18 citations
Semantic Scholar
PC-SPES decreases proliferation and induces differentiation and apoptosis of human acute myeloid leukemia cells.
T. Ikezoe, Sophie S. Chen, Tsuyako Saito, H. Asou +5 more
2003International Journal of Oncology17 citations
Semantic Scholar
Dose‐finding study of the checkpoint kinase 1 inhibitor, prexasertib, in Japanese patients with advanced solid tumors
S. Iwasa, N. Yamamoto, K. Shitara, K. Tamura +10 more
2018Cancer Science15 citations Open access
Semantic Scholar
Establishment of a myeloid leukaemia cell line (Kasumi‐4) with t(9;22;11)(q34;q11;q13), inv(3)(q21q26) and the EVI1 gene activation from a patient with chronic myelogenous leukaemia in blast crisis
H. Asou, M. Eguchi, K. Suzukawa, K. Morishita +4 more
1996British Journal of Haematology15 citations
Semantic Scholar
NEOPLASIA Loss of p 73 Gene Expression in Leukemias / Lymphomas Due to Hypermethylation
S. Kawano, C. Miller, A. Gombart, C. Bartram +6 more
199914 citations
Semantic Scholar
Comparison between turbo spin-echo and echo planar diffusion-weighted imaging of the female pelvis with 3T MRI
T. Yoshizako, Rika Yoshida, H. Asou, Megumi Nakamura +1 more
2021Acta Radiologica Open13 citations Open access
Semantic Scholar
Kasumi leukemia cell lines: characterization of tumor genomes with ethnic origin and scales of genomic alterations
F. Kasai, H. Asou, M. Ozawa, Kazuhiko Kobayashi +5 more
2020Human Cell12 citations Open access
Semantic Scholar
Dose‐escalation study of tabalumab with bortezomib and dexamethasone in Japanese patients with multiple myeloma
S. Iida, D. Ogiya, Y. Abe, M. Taniwaki +7 more
2016Cancer Science12 citations Open access
Semantic Scholar
Co-infection of HHV-6 and HHV-8 is rare in primary effusion lymphoma.
H. Asou, T. Tasaka, J. Said, M. Daibata +2 more
2000Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis12 citations
Semantic Scholar
The Dynactin Complex Maintains the Integrity of Metaphasic Centrosomes to Ensure Transition to Anaphase*
Y. Ozaki, H. Matsui, Akiko Nagamachi, H. Asou +2 more
2010Journal of Biological Chemistry11 citations Open access
Semantic Scholar
Activation of EVI1 transcripts with chromosomal translocation joining the TCRVβ locus and the EVI1 gene in human acute undifferentiated leukemia cell line (Kasumi-3) with a complex translocation of der(3)t(3;7;8)
K. Suzukawa, T. Kodera, Seiichi Shimizu, Toshiro Nagasawa +5 more
1999Leukemia9 citations Open access
Semantic Scholar
DPC 4/SMAD 4 in non-pancreatic tumors with frequent LOH 18q21 and in hematological malignancies.
W. Verbeek, K. Spirin, Y. Hatta, C. Miller +6 more
1997International Journal of Oncology9 citations
Semantic Scholar
Merestinib monotherapy or in combination for japanese patients with advanced and/or metastatic cancer: A phase 1 study
T. Doi, N. Yamamoto, Y. Naito, Y. Kuboki +6 more
2021Cancer Medicine7 citations Open access
Semantic Scholar
Phase 1 dose-escalation study of a novel oral PI3K/mTOR dual inhibitor, LY3023414, in patients with cancer
S. Kondo, M. Tajimi, Tomohiko Funai, Koichi Inoue +4 more
2020Investigational new drugs7 citations Open access
Semantic Scholar

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