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Alistair McGregor · SciRah

Researcher profile · Semantic Scholar

Alistair McGregor

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Alistair McGregor — researcher profile on SciRah

h-index: 20
Works: 54
Citations: 1,105

Most-cited papers

Multiple interactions control the intracellular localization of the herpes simplex virus type 1 capsid proteins.
F. Rixon, C. Addison, Alistair McGregor, Sharon J. Macnab +3 more
1996Journal of General Virology110 citations Open access
Semantic Scholar
Molecular cloning of the guinea pig cytomegalovirus (GPCMV) genome as an infectious bacterial artificial chromosome (BAC) in Escherichia coli.
Alistair McGregor, M. Schleiss
2001Molecular Genetics and Metabolism76 citations
Semantic Scholar
Preconceptual administration of an alphavirus replicon UL83 (pp65 homolog) vaccine induces humoral and cellular immunity and improves pregnancy outcome in the guinea pig model of congenital cytomegalovirus infection.
M. Schleiss, Juan C. Lacayo, Y. Belkaid, Alistair McGregor +5 more
2007Journal of Infectious Diseases75 citations
Semantic Scholar
Genotypic analysis of two hypervariable human cytomegalovirus genes
A. J. Bradley, I. Kovács, D. Gatherer, D. Dargan +17 more
2008Journal of Medical Virology68 citations Open access
Semantic Scholar
Analysis of the nucleotide sequence of the guinea pig cytomegalovirus (GPCMV) genome
Mark R. Schleiss, Alistair McGregor, Ye-On K. Choi, Shailesh V. Date +2 more
2008Virology Journal58 citations Open access
Semantic Scholar
Cloning the complete guinea pig cytomegalovirus genome as an infectious bacterial artificial chromosome with excisable origin of replication.
Xiao-Hong Cui, Alistair McGregor, M. Schleiss, Michael A. McVoy
2008Journal of Virological Methods52 citations Open access
Semantic Scholar
Molecular, Biological, and In Vivo Characterization of the Guinea Pig Cytomegalovirus (CMV) Homologs of the Human CMV Matrix Proteins pp71 (UL82) and pp65 (UL83)
Alistair McGregor, Fen-Yong Liu, M. Schleiss
2004Journal of Virology43 citations Open access
Semantic Scholar
A Homolog Pentameric Complex Dictates Viral Epithelial Tropism, Pathogenicity and Congenital Infection Rate in Guinea Pig Cytomegalovirus
Stewart M Coleman, Ye-On K. Choi, M. Root, Alistair McGregor
2016PLoS Pathogens38 citations Open access
Semantic Scholar
The non-nucleoside antiviral, BAY 38-4766, protects against cytomegalovirus (CMV) disease and mortality in immunocompromised guinea pigs.
M. Schleiss, D. Bernstein, Michael A. McVoy, G. Stroup +5 more
2005Antiviral Research38 citations Open access
Semantic Scholar
A bright future for bioluminescent imaging in viral research
Stewart M Coleman, Alistair McGregor
2015Future Virology37 citations Open access
Semantic Scholar
Protection against congenital cytomegalovirus (CMV) disease, conferred by a replication-disabled, bacterial artificial chromosome (BAC)-based DNA vaccine.
M. Schleiss, G. Stroup, K. Pogorzelski, Alistair McGregor
2006Vaccine35 citations
Semantic Scholar
A Novel Non-Replication-Competent Cytomegalovirus Capsid Mutant Vaccine Strategy Is Effective in Reducing Congenital Infection
Ye-On K. Choi, M. Root, Alistair McGregor
2016Journal of Virology33 citations Open access
Semantic Scholar
Viral Glycoprotein Complex Formation, Essential Function and Immunogenicity in the Guinea Pig Model for Cytomegalovirus
Stewart M Coleman, Julia Hornig, Sarah Maddux, Ye-On K. Choi +1 more
2015PLoS ONE31 citations Open access
Semantic Scholar
Inclusion of the Viral Pentamer Complex in a Vaccine Design Greatly Improves Protection against Congenital Cytomegalovirus in the Guinea Pig Model
Ye-On K. Choi, Nadia S. El-Hamdi, Alistair McGregor
2019Journal of Virology30 citations Open access
Semantic Scholar
Identification of essential and non-essential genes of the guinea pig cytomegalovirus (GPCMV) genome via transposome mutagenesis of an infectious BAC clone.
Alistair McGregor, Fen-Yong Liu, M. Schleiss
2004Virus Research30 citations
Semantic Scholar
Cytomegalovirus Antivirals and Development of Improved Animal Models
Alistair McGregor, Y. Choi
2011Expert Opinion on Drug Metabolism & Toxicology28 citations Open access
Semantic Scholar
Molecular Characterization of the Guinea Pig Cytomegalovirus UL83 (pp65) Protein Homolog
M. Schleiss, Alistair McGregor, N. Jensen, G. Erdem +1 more
2004Virus genes28 citations Open access
Semantic Scholar
The Impact of Genome Length on Replication and Genome Stability of the Herpesvirus Guinea Pig Cytomegalovirus
Xiao-Hong Cui, Alistair McGregor, M. Schleiss, Michael A. McVoy
2009Virology22 citations Open access
Semantic Scholar
Recent advances in herpesvirus genetics using bacterial artificial chromosomes.
Alistair McGregor, Mark R. Schleiss
2001Molecular Genetics and Metabolism22 citations
Semantic Scholar
Cytomegalovirus UL128 homolog mutants that form a pentameric complex produce virus with impaired epithelial and trophoblast cell tropism and altered pathogenicity in the guinea pig
Stewart M Coleman, Ye-On K. Choi, Alistair McGregor
2017Virology20 citations Open access
Semantic Scholar
Cyclic cidofovir (cHPMPC) prevents congenital cytomegalovirus infection in a guinea pig model
M. Schleiss, Jodi L. Anderson, Alistair McGregor
2006Virology Journal19 citations Open access
Semantic Scholar
A Fully Protective Congenital CMV Vaccine Requires Neutralizing Antibodies to Viral Pentamer and gB Glycoprotein Complexes but a pp65 T-Cell Response Is Not Necessary
Ye-On K. Choi, Alistair McGregor
2021Viruses15 citations Open access
Semantic Scholar
Requirements for guinea pig cytomegalovirus tropism and antibody neutralization on placental amniotic sac cells.
Ye-On K. Choi, Nadia S. El-Hamdi, Alistair McGregor
2020Journal of General Virology15 citations Open access
Semantic Scholar
Guinea pig cytomegalovirus GP84 is a functional homolog of the human cytomegalovirus (HCMV) UL84 gene that can complement for the loss of UL84 in a chimeric HCMV
Alistair McGregor, K. Y. Choi, Mark R. Schleiss
2010Virology15 citations Open access
Semantic Scholar
Neutralizing antibodies to gB based CMV vaccine requires full length antigen but reduced virus neutralization on non-fibroblast cells limits vaccine efficacy in the guinea pig model
Ye-On K. Choi, Nadia S. El-Hamdi, Alistair McGregor
2020Vaccine14 citations Open access
Semantic Scholar
The essential role of guinea pig cytomegalovirus (GPCMV) IE1 and IE2 homologs in viral replication and IE1-mediated ND10 targeting
Julia Hornig, Ye-On K. Choi, Alistair McGregor
2017Virology14 citations Open access
Semantic Scholar
Expression of the human cytomegalovirus UL97 gene in a chimeric guinea pig cytomegalovirus (GPCMV) results in viable virus with increased susceptibility to ganciclovir and maribavir.
Alistair McGregor, Ye-On K. Choi, Xiao-Hong Cui, Michael A. McVoy +1 more
2008Antiviral Research14 citations Open access
Semantic Scholar
Guinea pig cytomegalovirus trimer complex gH/gL/gO uses PDGFRA as universal receptor for cell fusion and entry
Nadia S. El-Hamdi, Ye-On K. Choi, Alistair McGregor
2020Virology13 citations Open access
Semantic Scholar
An Attenuated CMV Vaccine with a Deletion in Tegument Protein GP83 (pp65 Homolog) Protects against Placental Infection and Improves Pregnancy Outcome in a Guinea Pig Challenge Model
Mark R. Schleiss, Ryan J. Buus, Ye-On K. Choi, Alistair McGregor
2013Future Virology13 citations Open access
Semantic Scholar
Convalescent Immunity to Guinea Pig Cytomegalovirus Induces Limited Cross Strain Protection against Re-Infection but High-Level Protection against Congenital Disease
Ye-On K. Choi, Nadia S. El-Hamdi, Alistair McGregor
2020International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
Current and new cytomegalovirus antivirals and novel animal model strategies.
Alistair McGregor
2010Inflammation & Allergy - Drug Targets10 citations
Semantic Scholar
Guinea Pig Cytomegalovirus Protective T Cell Antigen GP83 Is a Functional pp65 Homolog for Innate Immune Evasion and Pentamer-Dependent Virus Tropism
Ye-On K. Choi, Nadia S. El-Hamdi, Julia Hornig, Alistair McGregor
2021Journal of Virology9 citations Open access
Semantic Scholar
A trimeric capable gB CMV vaccine provides limited protection against a highly cell associated and epithelial tropic strain of cytomegalovirus in guinea pigs.
Ye-On K. Choi, Nadia S. El-Hamdi, Alistair McGregor
2021Journal of General Virology9 citations Open access
Semantic Scholar
Design and development of antivirals and intervention strategies against human herpesviruses using high-throughput approach
Julia Hornig, Alistair McGregor
2014Expert Opinion on Drug Discovery8 citations
Semantic Scholar
Human Herpesviruses and Animal Models
Alistair McGregor, Ye-On K. Choi, S. Schachtele, J. Lokensgard
20138 citations
Semantic Scholar
Cross Strain Protection against Cytomegalovirus Reduces DISC Vaccine Efficacy against CMV in the Guinea Pig Model
Ye-On K. Choi, Nadia S. El-Hamdi, Alistair McGregor
2022Viruses7 citations Open access
Semantic Scholar
Endothelial Cell Infection by Guinea Pig Cytomegalovirus Is a Lytic or Persistent Infection Depending on Tissue Origin but Requires Viral Pentamer Complex and pp65 Tegument Protein
Ye-On K. Choi, Nadia S. El-Hamdi, Alistair McGregor
2022Journal of Virology7 citations Open access
Semantic Scholar
T cell inducing vaccine against cytomegalovirus immediate early 1 (IE1) protein provides high level cross strain protection against congenital CMV
Ye-On K. Choi, Nadia S. El-Hamdi, Alistair McGregor
2024Vaccine6 citations Open access
Semantic Scholar
Herpesvirus genome mutagenesis by transposon-mediated strategies.
Alistair McGregor, M. Schleiss
2004Methods in molecular biology5 citations
Semantic Scholar
Complete cross strain protection against congenital cytomegalovirus infection requires a vaccine encoding key antibody (gB) and T-cell (immediate early 1 protein) viral antigens
Ye-On K. Choi, Yushu Qin, Nadia S. El-Hamdi, Alistair McGregor
2025Frontiers in Immunology3 citations Open access
Semantic Scholar
The guinea pig as a relevant preclinical model in the rat race for a vaccine against congenital cytomegalovirus infection.
Ye-On K. Choi, Alistair McGregor
2025Virology3 citations Open access
Semantic Scholar
Genetically engineered live-attenuated cytomegalovirus (CMV) vaccines improve pregnancy outcome in the guinea-pig model of congenital CMV infection
M. Schleiss, Alistair McGregor, Ye-On K. Choi, Jodi L. Anderson +3 more
2008Retrovirology3 citations Open access
Semantic Scholar
Transposon and transposome mutagenesis of plasmids, cosmids, and BACs.
Alistair McGregor
2003Methods in molecular biology3 citations
Semantic Scholar
Complete cross strain protection against congenital cytomegalovirus infection requires a vaccine encoding key antibody (gB) and T-cell (immediate early 1 protein) viral antigens
Ye-On K. Choi, Yushu Qin, Nadia S. El-Hamdi, Alistair McGregor
2025bioRxiv2 citations Open access
Semantic Scholar
Selective knockout of key CMV receptors in fetal cells blocks direct and endocytic pathways of entry in the guinea pig
Yushu Qin, Ye-On K. Choi, Nadia S. El-Hamdi, Alistair McGregor
2025bioRxiv2 citations Open access
Semantic Scholar
A Chimeric Guinea Pig Cytomegalovirus (GPCMV) Encoding Wild Type or Mutant HCMV UL97 Renders GPCMV Susceptible or Resistant to Ganciclovir while Retaining an Ability to Disseminate in the Animal Host
Alistair McGregor, Jared Leibelt, C. Bouska, M. Schleiss
20102 citations
Semantic Scholar
Rapid generation of recombinant herpes simplex virus vectors expressing the bacterial lacZ gene under the control of neuronal promoters
Alistair McGregor, A. Roberts, R. Davies, J. Clements +1 more
19992 citations
Semantic Scholar
Vaccination as an Antiviral Strategy for Control of Cytomegalovirus (CMV) Disease: A Vectored Vaccine Approach Targeting the UL83 (pp65) Homolog Protects Against Congenital CMV Disease in the Guinea Pig Model
M. Schleiss, Juan C. Lacayo, Y. Belkaid, Alistair McGregor +5 more
20071 citations
Semantic Scholar
Cytomegalovirus pentamer dependent endocytic cellular infection utilizes redundant entry receptors in the guinea pig model
Yushu Qin, Ye-On K. Choi, Alistair McGregor
2026bioRxiv0 citations
Semantic Scholar
Knockout of key receptors (PDGFRA and NRP2) in the guinea pig model blocks direct and endocytic pathways of CMV cell entry
Yushu Qin, Ye-On K. Choi, Nadia S. El-Hamdi, Alistair McGregor
2026Journal of General Virology0 citations Open access
Semantic Scholar

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