L. Nyman

Most-cited papers

1. Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-adrenoceptor agonist.

   R. Virtanen, J. Savola, V. Saano, L. Nyman

   1988European Journal of Pharmacology757 citations

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2. Comparative studies on the cytochrome p450-associated metabolism and interaction potential of selegiline between human liver-derived in vitro systems.

   J. S. Salonen, L. Nyman, A. Boobis, R. Edwards +14 more

   2003Drug Metabolism And Disposition67 citations

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3. Tamoxifen and toremifene concentrations in plasma are greatly decreased by rifampin

   K. Kivistö, K. Villikka, L. Nyman, M. Anttila +1 more

   1998Clinical pharmacology and therapy54 citations

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4. Evaluation of the α1- and α2-adrenoceptor effects of detomidine, a novel veterinary sedative analgesic

   R. Virtanen, L. Nyman

   198548 citations

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5. Are Needle-Free Injections a Useful Alternative for Growth Hormone Therapy in Children? Safety and Pharmacokinetics of Growth Hormone Delivered by a New Needle-Free Injection Device Compared to a Fine Gauge Needle

   H. Dörr, S. Zabransky, Eberhard Keller, B. Otten +9 more

   2003Journal of Pediatric Endocrinology & Metabolism (JPEM)39 citations

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6. Autoradiographic characterization of α2C‐adrenoceptors in the human striatum

   V. Fagerholm, Johanna Rokka, L. Nyman, J. Sallinen +4 more

   2008Synapse38 citations Open access

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7. Pharmacological evidence for the involvement of alpha-2 adrenoceptors in the sedative effect of detomidine, a novel sedative-analgesic.

   R. Virtanen, H. Ruskoaho, L. Nyman

   1985Journal of Veterinary Pharmacology and Therapeutics38 citations

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8. Selegiline pharmacokinetics are unaffected by the CYP3A4 inhibitor itraconazole

   K. Kivistö, Jun-Sheng Wang, J. Backman, L. Nyman +3 more

   2001European Journal of Clinical Pharmacology33 citations

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9. The effects of metabolic inhibition and acidification on force production in the rat uterus

   S. Wray, K. Duggins, R. Iles, L. Nyman +1 more

   1992Experimental Physiology32 citations Open access

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10. Selegiline Metabolism and Cytochrome P450 Enzymes:In vitro Study in Human Liver Microsomes†

    P. Taavitsainen, M. Anttila, L. Nyman, Hari Karnani +2 more

    200026 citations

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11. CYP2D6 polymorphism is not crucial for the disposition of selegiline

    Harry Scheinin, M. Anttila, M. Dahl, Hari Karnani +4 more

    1998Clinical pharmacology and therapy24 citations

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12. Inhibition of MAO-A activity enhances behavioural activity of rats assessed using water maze and open arena tasks.

    Alexandra Barbelivien, L. Nyman, A. Haapalinna, J. Sirviö

    2001Acta Pharmacologica et Toxicologica17 citations

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13. CYP2C19 polymorphism is not important for the in vivo metabolism of selegiline

    K. Laine, M. Anttila, L. Nyman, A. Wahlberg +1 more

    2001European Journal of Clinical Pharmacology15 citations

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14. Effect of levosimendan therapy on myocardial infarct size and left ventricular function after acute coronary occlusion

    M. Tarkia, C. Stark, M. Haavisto, Rasmus Kentala +14 more

    2016Heart12 citations

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15. Effect of concomitant hormone replacement therapy containing estradiol and levonorgestrel on the pharmacokinetics of selegiline

    S. Palovaara, M. Anttila, L. Nyman, K. Laine

    2002European Journal of Clinical Pharmacology12 citations

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16. Comparative bioavailability of carbamazepine from two slow-release preparations.

    Mauri Reunanen, E. Heinonen, L. Nyman, Markku Anttila

    1992Epilepsy Research11 citations

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17. A thirteen week dietary toxicity study with 7-hydroxymatairesinol potassium acetate (HMRlignan) in rats.

    B. Lina, H. Korte, L. Nyman, M. Unkila

    2005Regulatory toxicology and pharmacology : RTP7 citations

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18. DU 127090: a highly potent, atypical dopamine receptor ligand — pilot study of dopamine D2 receptor occupancy after multiple oral administration of DU 127090 to healthy male volunteers, using 11C-raclopride by means of positron emission tomography

    M. de Vries, J. U. D. de Haes, S.-K. Long, A. Grahnén +4 more

    20007 citations

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19. MAO-B inhibition by a single dose of l-deprenyl or lazabemide does not prevent neuronal damage following focal cerebral ischaemia in rats.

    J. Jolkkonen, R. Kauppinen, L. Nyman, A. Haapalinna +1 more

    2008Acta Pharmacologica et Toxicologica6 citations Open access

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20. MAO‐B Inhibition by a Single Dose of l‐Deprenyl or Lazabemide Does Not Prevent Neuronal Damage Following Focal Cerebral Ischaemia in Rats

    J. Jolkkonen, R. Kauppinen, L. Nyman, A. Haapalinna +1 more

    20006 citations Open access

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21. Evaluation of the alpha 1- and alpha 2-adrenoceptor effects of detomidine, a novel veterinary sedative analgesic.

    R. Virtanen, L. Nyman

    1985European Journal of Pharmacology6 citations

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22. DU127090: A novel partial dopamine agonist with antipsychotic activity: Pilot study of dopamine D2 receptor occupancy after multiple oral administration of DU127090 to healthy male volunteers, using11C-raclopride by means of positron emission tomography

    M. de Vries, J. U. D. de Haes, L. Nyman, Anders Wall

    20032 citations

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