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S. Imajo · SciRah

Researcher profile · Semantic Scholar

S. Imajo

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S. Imajo — researcher profile on SciRah

h-index: 17
Works: 69
Citations: 985

Most-cited papers

Cloning and sequence of the gene encoding a cefotaxime-hydrolyzing class A beta-lactamase isolated from Escherichia coli
Y. Ishii, A. Ohno, H. Taguchi, S. Imajo +2 more
1995Antimicrobial Agents and Chemotherapy213 citations Open access
Semantic Scholar
The carcinoembryonic antigen (CEA) contains multiple immunoglobulin-like domains.
S. Oikawa, S. Imajo, Teruhisa Noguchi, G. Kosaki +1 more
1987Biochemical and Biophysical Research Communications - BBRC104 citations
Semantic Scholar
A single amino acid substitution converts cytochrome P450(14DM) to an inactive form, cytochrome P450SG1: complete primary structures deduced from cloned DNAS.
Nobuhiro Ishida, Yuri Aoyama, Ritsuko Hatanaka, Yoshiaki Oyama +9 more
1988Biochemical and Biophysical Research Communications - BBRC63 citations
Semantic Scholar
Small-molecule inhibition of PTPRZ reduces tumor growth in a rat model of glioblastoma
A. Fujikawa, Asako Nagahira, H. Sugawara, Kentaro Ishii +11 more
2016Scientific Reports57 citations Open access
Semantic Scholar
Substituted 3-(phenylsulfonyl)-1-phenylimidazolidine-2,4-dione derivatives as novel nonpeptide inhibitors of human heart chymase.
Shinjiro Niwata, Harukazu Fukami, Motoo Sumida, Akiko Ito +18 more
1997Journal of Medicinal Chemistry32 citations Open access
Semantic Scholar
Modeling study on a hydrolytic mechanism of class A β-lactamases
M. Ishiguro, S. Imajo
199631 citations
Semantic Scholar
A facile conversion of the phenylthio group to acetoxy by copper reagents for a practical synthesis of 4-acetoxyazetidin-2-one derivatives from (R)-butane-1,3-diol
T. Nakatsuka, H. Iwata, R. Tanaka, S. Imajo +1 more
199130 citations
Semantic Scholar
Minimum structure requirement of immunomodulatory glycolipids for predominant Th2 cytokine induction and the discovery of non-linear phytosphingosine analogs.
Tetsuya Toba, Kenji Murata, K. Nakanishi, Bitoku Takahashi +7 more
2007Bioorganic & Medicinal Chemistry Letters29 citations
Semantic Scholar
Substituted 3-phenylsulfonylquinazoline-2,4-dione derivatives as novel nonpeptide inhibitors of human heart chymase.
H. Fukami, S. Imajo, Akiko Ito, Saki Kakutani +10 more
2000Drug Design and Discovery28 citations
Semantic Scholar
Synthesis and biological evaluation of new 4-arylpiperidines and 4-aryl-4-piperidinols: dual Na+ and Ca2+ channel blockers with reduced affinity for dopamine D2 receptors
H. Annoura, K. Nakanishi, M. Uesugi, Atsuko Fukunaga +4 more
200227 citations
Semantic Scholar
Absolute configuration of C-1027 chromophore
K. Iida, Sumiko Fukuda, Toŝhiyuki Tanaka, M. Hirama +4 more
199627 citations
Semantic Scholar
Mouse mast cell protease-1 cleaves angiotensin I to form angiotensin II.
Kayo Saito, Tsuyoshi Muto, Y. Tomimori, S. Imajo +4 more
2003Biochemical and Biophysical Research Communications - BBRC26 citations
Semantic Scholar
Solution structure of the antitumour antibiotic neocarzinostatin, a chromophore–protein complex
Toŝhiyuki Tanaka, M. Hirama, K. Fujita, S. Imajo +1 more
199322 citations
Semantic Scholar
Structure-activity relationships of penem antibiotics: crystallographic structures and implications for their antimicrobial activities.
Rie Tanaka, Y. Oyama, S. Imajo, S. Matsuki +1 more
1997Bioorganic & Medicinal Chemistry21 citations
Semantic Scholar
Identification of 6-substituted 4-arylsulfonyl-1,4-diazepane-2,5-diones as a novel scaffold for human chymase inhibitors.
Taisaku Tanaka, Tsuyoshi Muto, H. Maruoka, S. Imajo +4 more
2007Bioorganic & Medicinal Chemistry Letters20 citations Open access
Semantic Scholar
Development of 6-benzyl substituted 4-aminocarbonyl-1,4-diazepane-2,5-diones as orally active human chymase inhibitors.
H. Maruoka, Tsuyoshi Muto, Taisaku Tanaka, S. Imajo +3 more
2007Bioorganic & Medicinal Chemistry Letters19 citations Open access
Semantic Scholar
Discovery of (2S)-1-(4-amino-2,3,5- trimethylphenoxy)-3-[4-[4-(4- fluorobenzyl)phenyl]-1-piperazinyl]-2-propanol dimethanesulfonate (SUN N8075): a dual Na(+) and Ca(2+) channel blocker with antioxidant activity.
Hirokazu Annoura, K. Nakanishi, Tetsuya Toba, Naohiro Takemoto +4 more
2000Journal of Medicinal Chemistry17 citations Open access
Semantic Scholar
Proton NMR studies on the chromophore binding structure in neocarzinostatin complex
Toŝhiyuki Tanaka, M. Hirama, Masako Ueno, S. Imajo +4 more
199117 citations
Semantic Scholar
Discovery and structure-activity relationship study of 1,3,6-trisubstituted 1,4-diazepane-7-ones as novel human kallikrein 7 inhibitors.
H. Murafuji, Hiroki Sakai, M. Goto, S. Imajo +2 more
2017Bioorganic & Medicinal Chemistry Letters16 citations Open access
Semantic Scholar
Absolute configuration of dimethyl tert-butylsuccinate and tert-butyl-.alpha.-naphthylacetic acid: degradation of the aromatic ring with ruthenium tetroxide
S. Imajo, Hiroko Kuritani, K. Shingū, M. Nakagawa
197913 citations
Semantic Scholar
Discovery and structure-activity relationship of imidazolinylindole derivatives as kallikrein 7 inhibitors.
H. Murafuji, Tsuyoshi Muto, M. Goto, S. Imajo +6 more
2019Bioorganic & Medicinal Chemistry Letters12 citations
Semantic Scholar
Modeling study of the structure of the macromolecular antitumor antibiotic neocarzinostatin. Origin of the stabilization of the chromophore.
M. Ishiguro, S. Imajo, M. Hirama
1991Journal of Medicinal Chemistry12 citations
Semantic Scholar
Structure-based drug design to overcome species differences in kallikrein 7 inhibition of 1,3,6-trisubstituted 1,4-diazepan-7-ones.
H. Murafuji, H. Sugawara, M. Goto, Y. Oyama +4 more
2018Bioorganic & Medicinal Chemistry10 citations Open access
Semantic Scholar
Structure-based drug design of 1,3,6-trisubstituted 1,4-diazepan-7-ones as selective human kallikrein 7 inhibitors.
H. Murafuji, Hiroki Sakai, M. Goto, Y. Oyama +4 more
2018Bioorganic & Medicinal Chemistry Letters10 citations Open access
Semantic Scholar
Synthesis and biological evaluation of truncated α-galactosylceramide derivatives focusing on cytokine induction profile.
Tetsuya Toba, Kenji Murata, J. Futamura, K. Nakanishi +9 more
2012Bioorganic & Medicinal Chemistry9 citations
Semantic Scholar
Synthesis and biological evaluation of new 4-arylpiperidines and 4-aryl-4-piperidinols: dual Na(+) and Ca(2+) channel blockers with reduced affinity for dopamine D(2) receptors.
H. Annoura, K. Nakanishi, M. Uesugi, Atsuko Fukunaga +4 more
2002Bioorganic & Medicinal Chemistry9 citations
Semantic Scholar
A survey of a functional amino acid of class Cβ‐lactamase corresponding to Glu166 of class A β‐lactamases
M. Nukaga, K. Tanimoto, K. Tsukamoto, S. Imajo +2 more
19939 citations
Semantic Scholar
5,6-Cis-penems: broad-spectrum anti-methicillin-resistant Staphylococcus aureus beta-lactam antibiotics.
M. Ishiguro, R. Tanaka, Koushi Namikawa, T. Nasu +4 more
1997Journal of Medicinal Chemistry8 citations
Semantic Scholar
Modeling study on a hydrolytic mechanism of class A beta-lactamases.
M. Ishiguro, S. Imajo
1996Journal of Medicinal Chemistry8 citations
Semantic Scholar
On the conformation of Phe78 of a chromoprotein antibiotic, neocarzinostatin.
S. Imajo, M. Ishiguro, Toŝhiyuki Tanaka, M. Hirama +1 more
1995Bioorganic & Medicinal Chemistry8 citations
Semantic Scholar
Zinc protease of Bacillus subtilis var. amylosacchariticus: construction of a three-dimensional model and comparison with thermolysin.
D. Tsuru, S. Imajo, Shinsuke Morikawa, T. Yoshimoto +1 more
1993Journal of Biochemistry (Tokyo)7 citations
Semantic Scholar
Photoinduced isomerisation of a 5,6-trans-penem to a cis-penem
H. Iwata, R. Tanaka, S. Imajo, Y. Oyama +1 more
19917 citations
Semantic Scholar
Structure-based design, synthesis, and binding mode analysis of novel and potent chymase inhibitors.
Junko Futamura-Takahashi, Taisaku Tanaka, H. Sugawara, Shinzo Iwashita +3 more
2018Bioorganic & Medicinal Chemistry Letters6 citations Open access
Semantic Scholar
Studies on the structure-function relationship of the HNK-1 associated glucuronyltransferase, GlcAT-P, by computer modeling and site-directed mutagenesis.
K. Ohtsubo, S. Imajo, M. Ishiguro, Takako Nakatani +2 more
2000Journal of Biochemistry (Tokyo)6 citations
Semantic Scholar
OPTICAL ACTIVITY DUE TO EXCITON INTERACTION BETWEEN 1B TRANSITIONS OF BENZENE CHROMOPHORES
K. Shingū, S. Imajo, Hiroko Kuritani, S. Hagishita +1 more
19836 citations
Semantic Scholar
Discovery of novel series of 6-benzyl substituted 4-aminocarbonyl-1,4-diazepane-2,5-diones as human chymase inhibitors using structure-based drug design.
Taisaku Tanaka, H. Sugawara, H. Maruoka, S. Imajo +1 more
2013Bioorganic & Medicinal Chemistry5 citations Open access
Semantic Scholar
Computational Analysis of Protein-Ligand Interaction
M. Ishiguro, S. Imajo
19965 citations
Semantic Scholar
Modified thrombin receptor-agonist peptide ligands. Synthesis and conformational analysis of analogs of the N-terminal tripeptide region
T. Shimamoto, Hiroko Tsuboi, Y. Kitajima, T. Miyazaki +3 more
19955 citations
Semantic Scholar
Stereospecific, photochemical rearrangement of 1,1′-spirobiindene and 1,1′-spirobi[benzindene]S
S. Imajo, K. Shingū, Hiroko Kuritani, A. Kato
19813 citations
Semantic Scholar
Quinazoline derivatives and therapeutic uses thereof
H. Fukami, A. Ito, S. Imajo
19992 citations
Semantic Scholar
Water-Soluble Class C β-Lactamase Catalytic Residue Mimic: Effect of Proximally Positioned Functional Groups on their pKa Values
Y. Kato-Toma, S. Imajo, M. Ishiguro
19982 citations
Semantic Scholar
Structure-activity relationship study on N-glycosyl moieties through model building of DNA and ellipticine N-glycoside complex
T. Shimamoto, S. Imajo, T. Honda, Satomichi Yoshimura +1 more
19962 citations
Semantic Scholar
Computational Analysis of Protein-Ligand Interaction
M. Ishiguro, S. Imajo
19962 citations Open access
Semantic Scholar
The specific inhibition of crystal growth of monohydrogen potassium L-tartrate by d-catechin.
S. Imajo, M. Ishiguro, K. Ishiguro, Tokiko Murashima +3 more
1994Bioorganic & Medicinal Chemistry2 citations
Semantic Scholar
Effect of spiroconjugation on the UV and CD spectra of 1,1′-spirobiindene
K. Shingū, Hiroko Kuritani, A. Kato, S. Imajo
19802 citations
Semantic Scholar
Absolute configuration and conformation of 1,1′-spirobi [benz[f] indan]
S. Imajo, K. Shingū, Hiroko Kuritani
19802 citations
Semantic Scholar
Conformational dependence of circular dichroism of 1,1′-spirobi[benz[e]indan]
S. Imajo, A. Nakamura, K. Shingū, A. Kato +1 more
19792 citations
Semantic Scholar
The role of water molecules in the deacylation of acylated structures of class A beta-lactamase.
M. Ishiguro, S. Imajo
1999Drug Design and Discovery1 citations
Semantic Scholar
A hydrate of the sodium salt of a penem carboxylic acid
Y. Oyama, S. Imajo, R. Tanaka, M. Ishiguro
19941 citations
Semantic Scholar
A Facile Conversion of the Phenylthio Group to Acetoxy by Copper Reagents for a Practical Synthesis of 4‐Acetoxyazetidin‐2‐one Derivatives from (R)‐Butane‐1,3‐diol.
T. Nakatsuka, H. Iwata, R. Tanaka, S. Imajo +1 more
19911 citations
Semantic Scholar

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