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J. Laffaire · SciRah

Researcher profile · Semantic Scholar

J. Laffaire

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J. Laffaire — researcher profile on SciRah

h-index: 18
Works: 28
Citations: 3,077

Most-cited papers

Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas.
M. Sanson, Y. Marie, S. Paris, A. Idbaih +7 more
2009Journal of Clinical Oncology978 citations Open access
Semantic Scholar
Ectopic Activation of Germline and Placental Genes Identifies Aggressive Metastasis-Prone Lung Cancers
S. Rousseaux, A. Debernardi, Baptiste Jacquiau, Anne-Laure Vitte +13 more
2013Science Translational Medicine550 citations Open access
Semantic Scholar
IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas
C. Houillier, Xiao-Wei Wang, G. Kaloshi, K. Mokhtari +9 more
2010Neurology517 citations
Semantic Scholar
All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2
M. Labussière, A. Idbaih, X. Wang, Y. Marie +12 more
2010Neurology266 citations
Semantic Scholar
Methylation profiling identifies 2 groups of gliomas according to their tumorigenesis.
J. Laffaire, Sibille Everhard, A. Idbaih, E. Crinière +9 more
2011Neuro-Oncology122 citations Open access
Semantic Scholar
Polytherapy with a combination of three repurposed drugs (PXT3003) down-regulates Pmp22 over-expression and improves myelination, axonal and functional parameters in models of CMT1A neuropathy
I. Chumakov, A. Milet, N. Cholet, G. Primas +15 more
2014Orphanet Journal of Rare Diseases88 citations Open access
Semantic Scholar
Genomic Aberrations in Lung Adenocarcinoma in Never Smokers
B. Job, A. Bernheim, M. Beau-Faller, S. Camilleri-Broët +8 more
2010PLoS ONE77 citations Open access
Semantic Scholar
A Comparative and Integrative Approach Identifies ATPase Family, AAA Domain Containing 2 as a Likely Driver of Cell Proliferation in Lung Adenocarcinoma
Robert Fouret, J. Laffaire, P. Hofman, M. Beau-Faller +8 more
2012Clinical Cancer Research74 citations
Semantic Scholar
Gene expression signature of cerebellar hypoplasia in a mouse model of Down syndrome during postnatal development
J. Laffaire, I. Rivals, L. Dauphinot, Fabien Pasteau +9 more
2009BMC Genomics54 citations Open access
Semantic Scholar
A novel TMEM127 mutation in a patient with familial bilateral pheochromocytoma.
N. Burnichon, C. Lepoutre-lussey, J. Laffaire, Noémie Gadessaud +6 more
2011European Journal of Endocrinology51 citations Open access
Semantic Scholar
Proliferation deficits and gene expression dysregulation in Down's syndrome (Ts1Cje) neural progenitor cells cultured from neurospheres
Randal X. Moldrich, L. Dauphinot, J. Laffaire, T. Vitalis +8 more
2009Journal of Neuroscience Research47 citations Open access
Semantic Scholar
Down syndrome gene dosage imbalance on cerebellum development.
R. Moldrich, L. Dauphinot, J. Laffaire, J. Rossier +1 more
2007Progress in neurobiology45 citations
Semantic Scholar
Lung Squamous Cell Carcinomas with Basaloid Histology Represent a Specific Molecular Entity
C. Brambilla, J. Laffaire, S. Lantuejoul, D. Moro-Sibilot +9 more
2014Clinical Cancer Research43 citations Open access
Semantic Scholar
Increased NR2A expression and prolonged decay of NMDA-induced calcium transient in cerebellum of TgDyrk1A mice, a mouse model of Down syndrome.
X. Altafaj, J. Ortiz-Abalia, Miriam Fernandez, M. Potier +7 more
2008Neurobiology of Disease35 citations Open access
Semantic Scholar
Combination of acamprosate and baclofen as a promising therapeutic approach for Parkinson’s disease
R. Hajj, A. Milet, Damien Toulorge, N. Cholet +8 more
2015Scientific Reports34 citations Open access
Semantic Scholar
Chromosome 9p and 10q losses predict unfavorable outcome in low-grade gliomas.
C. Houillier, K. Mokhtari, C. Carpentier, E. Crinière +9 more
2010Neuro-Oncology23 citations Open access
Semantic Scholar
Combination of acamprosate and baclofen (PXT864) as a potential new therapy for amyotrophic lateral sclerosis
L. Boussicault, J. Laffaire, P. Schmitt, P. Rinaudo +4 more
2020Journal of Neuroscience Research21 citations Open access
Semantic Scholar
Synergistic PXT3003 therapy uncouples neuromuscular function from dysmyelination in male Charcot–Marie–Tooth disease type 1A (CMT1A) rats
T. Prukop, S. Wernick, L. Boussicault, D. Ewers +20 more
2020Journal of Neuroscience Research21 citations Open access
Semantic Scholar
Peer Review #1 of "Clinical characteristics and prognosis of basaloid squamous cell carcinoma of the lung: a population-based analysis (v0.2)"
Guang-Da Yuan, C. Zhan, Yi-Wei Huang, Dong-Lin Zhu +201 more
201913 citations Open access
Semantic Scholar
An ANOCEF Genomic and Transcriptomic Microarray Study of the Response to Irinotecan and Bevacizumab in Recurrent Glioblastomas
J. Laffaire, A. D. Di Stefano, O. Chinot, A. Idbaih +10 more
2014BioMed Research International11 citations Open access
Semantic Scholar
Translational Relevance
C. Brambilla, J. Laffaire, S. Lantuejoul, D. Moro-Sibilot +8 more
4 citations
Semantic Scholar
Predictive impact of IDH1 or IDH2 mutations on outcome and response to temozolomide in low-grade gliomas.
C. Houillier, Xiao-Wei Wang, G. Kaloshi, K. Mokhtari +6 more
20103 citations
Semantic Scholar
SPECIAL I SSUE Transcriptional disruptions in Down syndrome: a case study in the Ts1Cje mouse cerebellum during post-natal development
I. Rivals, G. Mercier, L. Ettwiller, R. Moldrich +4 more
20061 citations
Semantic Scholar
Author response for "Synergistic PXT3003 therapy uncouples neuromuscular function from dysmyelination in male Charcot-Marie-Tooth disease type 1A (CMT1A) rats"
Thomas Prukop, Stephanie Wernick, L. Boussicault, David Ewers +20 more
20200 citations Open access
Semantic Scholar
Author response for "Combination of acamprosate and baclofen (PXT864) as a potential new therapy for amyotrophic lateral sclerosis"
L. Boussicault, J. Laffaire, Peter Schmitt, P. Rinaudo +4 more
20200 citations Open access
Semantic Scholar
Author response for "Combination of acamprosate and baclofen (PXT864) as a potential new therapy for amyotrophic lateral sclerosis"
L. Boussicault, J. Laffaire, Peter Schmitt, P. Rinaudo +4 more
20200 citations Open access
Semantic Scholar
Biology of Human Tumors Lung Squamous Cell Carcinomas with Basaloid Histology Represent a Speci fi c Molecular Entity
C. Brambilla, J. Laffaire, S. Lantuejoul, D. Moro-Sibilot +8 more
20140 citations
Semantic Scholar
Lepidic and non-lepidic adenocarcinomas have distinct gene expression signatures that correlate with aggressiveness
P. Fouret, Robert Fouret, J. Laffaire
2013European Respiratory Journal0 citations
Semantic Scholar

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