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P. Serradas · SciRah

Researcher profile · Semantic Scholar

P. Serradas

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P. Serradas — researcher profile on SciRah

h-index: 27
Works: 60
Citations: 3,658

Most-cited papers

Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection
Christoph A. Thaiss, M. Levy, I. Grosheva, D. Zheng +19 more
2018Science854 citations Open access
Semantic Scholar
Consequences of fetal exposure to maternal diabetes in offspring.
L. Fetita, E. Sobngwi, P. Serradas, F. Calvo +1 more
2006Journal of Clinical Endocrinology and Metabolism295 citations Open access
Semantic Scholar
β-Cell Insensitivity to Glucose in the GK Rat, a Spontaneous Nonobese Model for Type II Diabetes
B. Portha, P. Serradas, D. Bailbe, Ken-ichi T. Suzuki +2 more
1991Diabetes258 citations
Semantic Scholar
Islet Inflammation and Fibrosis in a Spontaneous Model of Type 2 Diabetes, the GK Rat
F. Homo-Delarche, S. Calderari, J. Irminger, M. Gangnerau +6 more
2006Diabetes212 citations Open access
Semantic Scholar
The rat models of non-insulin dependent diabetes induced by neonatal streptozotocin.
B. Portha, O. Blondel, P. Serradas, R. McEvoy +3 more
1989Diabete & metabolisme191 citations
Semantic Scholar
Impaired development of pancreatic beta-cell mass is a primary event during the progression to diabetes in the GK rat
J. Movassat, C. Saulnier, P. Serradas, Bernard Portha
1997Diabetologia164 citations Open access
Semantic Scholar
GLUT2 Accumulation in Enterocyte Apical and Intracellular Membranes
Amal Ait-Omar, Milena Monteiro-Sepulveda, C. Poitou, M. le Gall +14 more
2011Diabetes152 citations Open access
Semantic Scholar
Insulin Internalizes GLUT2 in the Enterocytes of Healthy but Not Insulin-Resistant Mice
V. Tobin, M. le Gall, X. Fioramonti, É. Stolarczyk +8 more
2008Diabetes138 citations Open access
Semantic Scholar
Beta-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetes.
B. Portha, P. Serradas, D. Bailbé, K. Suzuki +2 more
1991Diabetes101 citations
Semantic Scholar
beta-cell function and viability in the spontaneously diabetic GK rat: information from the GK/Par colony.
B. Portha, M. Giroix, P. Serradas, M. N. Gangnerau +6 more
2001Diabetes89 citations
Semantic Scholar
Detection of extracellular glucose by GLUT2 contributes to hypothalamic control of food intake.
É. Stolarczyk, C. Guissard, A. Michau, P. Even +7 more
2010American Journal of Physiology. Endocrinology and Metabolism81 citations Open access
Semantic Scholar
Intestinal invalidation of the glucose transporter GLUT2 delays tissue distribution of glucose and reveals an unexpected role in gut homeostasis
C. Schmitt, Thomas Aranias, T. Viel, D. Château +12 more
2016Molecular Metabolism78 citations Open access
Semantic Scholar
Specific inhibition of GLUT2 in arcuate nucleus by antisense oligonucleotides suppresses nervous control of insulin secretion.
C. Leloup, M. Orosco, P. Serradas, S. Nicolaidis +1 more
1998Brain Research. Molecular Brain Research75 citations
Semantic Scholar
Defective IGF2 and IGF1R protein production in embryonic pancreas precedes beta cell mass anomaly in the Goto–Kakizaki rat model of type 2 diabetes
S. Calderari, M. Gangnerau, M. Thibault, M. Meile +4 more
2007Diabetologia67 citations Open access
Semantic Scholar
Mitochondrial deoxyribonucleic acid content is specifically decreased in adult, but not fetal, pancreatic islets of the Goto-Kakizaki rat, a genetic model of noninsulin-dependent diabetes.
P. Serradas, M. Giroix, C. Saulnier, M. Gangnerau +4 more
1995Endocrinology67 citations
Semantic Scholar
Insulin Production and Glucose Metabolism in Isolated Pancreatic Islets of Rats With NIDDM
B. Portha, M. Giroix, P. Serradas, N. Welsh +3 more
1988Diabetes67 citations
Semantic Scholar
Decreased glucose-induced cAMP and insulin release in islets of diabetic rats: reversal by IBMX, glucagon, GIP.
N. Dachicourt, P. Serradas, M. Giroix, Marie-Noëlle Gangnerau +1 more
1996American Journal of Physiology53 citations
Semantic Scholar
Fetal insulin-like growth factor-2 production is impaired in the GK rat model of type 2 diabetes.
P. Serradas, L. Goya, Matthieu Lacorne, M. Gangnerau +4 more
2002Diabetes47 citations
Semantic Scholar
Impaired pancreatic beta cell function in the fetal GK rat. Impact of diabetic inheritance.
P. Serradas, Marie-Noëlle Gangnerau, M. Giroix, C. Saulnier +1 more
1998Journal of Clinical Investigation46 citations Open access
Semantic Scholar
Loss of Sugar Detection by GLUT2 Affects Glucose Homeostasis in Mice
É. Stolarczyk, M. le Gall, P. Even, A. Houllier +3 more
2007PLoS ONE45 citations Open access
Semantic Scholar
Type 2 diabetes is associated with impaired jejunal enteroendocrine GLP-1 cell lineage in human obesity
Céline Osinski, Léa Le Gléau, C. Poitou, J. de Toro-Martín +10 more
2020International Journal of Obesity43 citations Open access
Semantic Scholar
Type 2 diabetes – a matter of failing β‐cell neogenesis? Clues from the GK rat model
J. Movassat, S. Calderari, E. Fernández, M. Martín +6 more
2007Diabetes, obesity and metabolism41 citations Open access
Semantic Scholar
Lipid-rich diet enhances L-cell density in obese subjects and in mice through improved L-cell differentiation
Thomas Aranias, A. Grosfeld, C. Poitou, Amal Ait Omar +11 more
2015Journal of Nutritional Science40 citations Open access
Semantic Scholar
Glucagon-like peptide-1(7-36)-amide confers glucose sensitivity to previously glucose-incompetent beta-cells in diabetic rats: in vivo and in vitro studies.
N. Dachicourt, P. Serradas, D. Bailbé, M. Kergoat +2 more
1997Journal of Endocrinology38 citations
Semantic Scholar
Effect of gliclazide treatment on insulin secretion and beta-cell mass in non-insulin dependent diabetic Goto-Kakisaki rats.
Nathalie Dachicourt, D. Bailbe, Marie-Noelle Gangnerau, P. Serradas +2 more
1998European Journal of Pharmacology29 citations
Semantic Scholar
The desensitization of normal B-cells to glucose in vitro is transient and not related to high glucose levels.
M. Giroix, P. Serradas, Bernard Portha
1989Endocrinology29 citations
Semantic Scholar
Restitution of defective glucose-stimulated insulin secretion in diabetic GK rat by acetylcholine uncovers paradoxical stimulatory effect of beta-cell muscarinic receptor activation on cAMP production.
M. Dolz, D. Bailbe, M. Giroix, S. Calderari +5 more
2005Diabetes28 citations Open access
Semantic Scholar
Mutations in SLC2A2 Gene Reveal hGLUT2 Function in Pancreatic β Cell Development*
A. Michau, G. Guillemain, A. Grosfeld, S. Vuillaumier-Barrot +11 more
2013Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Protein-caloric food restriction affects insulin-like growth factor system in fetal Wistar rat.
M. A. Martín, P. Serradas, S. Ramos, E. Fernández +7 more
2005Endocrinology26 citations Open access
Semantic Scholar
Regenerating 1 and 3b Gene Expression in the Pancreas of Type 2 Diabetic Goto-Kakizaki (GK) Rats
S. Calderari, J. Irminger, M. Giroix, J. Ehses +7 more
2014PLoS ONE25 citations Open access
Semantic Scholar
Glucose Tolerance Is Improved in Mice Invalidated for the Nuclear Receptor HNF-4γ: A Critical Role for Enteroendocrine Cell Lineage
F. Baraille, S. Ayari, V. Carrière, Céline Osinski +8 more
2015Diabetes24 citations Open access
Semantic Scholar
Predominant role of GIP in the development of a metabolic syndrome-like phenotype in female Wistar rats submitted to forced catch-up growth.
J. de Toro-Martín, E. Fernández-Millán, E. Lizárraga-Mollinedo, E. López-Oliva +3 more
2014Endocrinology19 citations Open access
Semantic Scholar
Improvement in glucose-induced insulin secretion in diabetic rats after long-term gliclazide treatment: a comparative study using different models of non-insulin-dependent diabetes mellitus induced by neonatal streptozotocin.
Bernard Portha, P. Serradas
1991American Journal of Medicine18 citations
Semantic Scholar
Undernutrition does not alter the activation of beta-cell neogenesis and replication in adult rats after partial pancreatectomy.
E. Fernández, M. Martín, S. Fajardo, D. Bailbe +5 more
2006American Journal of Physiology. Endocrinology and Metabolism17 citations
Semantic Scholar
Enteroendocrine System and Gut Barrier in Metabolic Disorders
Céline Osinski, Dounia Moret, K. Clément, P. Serradas +1 more
2022International Journal of Molecular Sciences16 citations Open access
Semantic Scholar
Neonatally Streptozotocin- Induced (n-STZ) Diabetic Rats: A Family of Type 2 Diabetes Models
P. Serradas, M. Dolz, M. Giroix, D. Bailbé +4 more
200716 citations
Semantic Scholar
Abnormal B‐Cell Function in Rats with Non‐Insulin‐Dependent Diabetes Induced by Neonatal Streptozotocin: Effect of In Vivo Insulin, Phlorizin, or Vanadate Treatments
P. Serradas, D. Bailbé, O. Blondel, Bernard Portha
1991Pancreas16 citations
Semantic Scholar
Is Defective Pancreatic Beta-cell Mass Environmentally Programmed in Goto-Kakizaki Rat Model of Type 2 Diabetes?: Insights From Crossbreeding Studies During Suckling Period
S. Calderari, M. Gangnerau, M. Meile, B. Portha +1 more
2006Pancreas15 citations
Semantic Scholar
Genetic analyses of glucose transporter genes in French non-insulin-dependent diabetic families.
S. Lesage, H. Zouali, N. Vionnet, A. Philippi +5 more
1997Diabetes & Metabolism14 citations
Semantic Scholar
Glucose refractoriness of pancreatic beta-cells in rat models of non-insulin dependent diabetes.
Bernard Portha, M. Giroix, P. Serradas, L. Morin +2 more
1994Diabete & metabolisme14 citations
Semantic Scholar
Islet Inflammation in Type 2 Diabetes (T2D): From Endothelial to β-Cell Dysfunction
J. Ehses, Sophie Calderari, J. Irminger, P. Serradas +5 more
200712 citations
Semantic Scholar
Benfluorex Normalizes Hyperglycemia and Reverses Hepatic Insulin Resistance in STZ-Induced Diabetic Rats
P. Serradas, O. Blondel, D. Bailbe, B. Portha
1993Diabetes12 citations
Semantic Scholar
Long-term gliclazide treatment improves the in vitro glucose-induced insulin release in rats with Type 2 (non-insulin-dependent) diabetes induced by neonatal streptozotocin
P. Serradas, D. Bailbe, Bernard Portha
1989Diabetologia12 citations Open access
Semantic Scholar
Intestinal alteration of a-gustducin and sweet taste signaling pathway in metabolic diseases is partly rescued after weight loss and diabetes remission.
L. le Gléau, C. Rouault, Céline Osinski, Edi Prifti +8 more
2021American Journal of Physiology. Endocrinology and Metabolism11 citations Open access
Semantic Scholar
HNF4g invalidation prevents diet-induced obesity via intestinal lipid malabsorption.
S. Ayari, Eva Gil-Iturbe, Léa le Gléau, Céline Osinski +7 more
2021Journal of Endocrinology8 citations Open access
Semantic Scholar
Insulin Secretion and Glucose Tolerance after Islet Transplantation in Rats with Noninsulin-Dependent Diabetes Induced by Neonatal Streptozotocin
M. Tormo, T. León-Quinto, C. Saulnier, D. Bailbe +2 more
1997Cell Transplantation6 citations
Semantic Scholar
Undernutrition of the GK rat during gestation improves pancreatic IGF-2 and beta-cell mass in the fetuses
E. Fernández-Millán, M. Gangnerau, Laura De Miguel-Santos, S. Calderari +4 more
2009Growth Factors5 citations
Semantic Scholar
Glucagon-like peptide-1 ( 7 – 36 )-amide confers glucose sensitivity to previously glucose-incompetent â-cells in diabetic rats : in vivo and in vitro studies
N. Dachicourt, P. Serradas, D. Bailbé, M. Kergoat +2 more
19975 citations
Semantic Scholar
Effect of benfluorex on insulin secretion and insulin action in streptozotocin-diabetic rats.
Bernard Portha, P. Serradas, D. Bailbe, O. Blondel +1 more
1993Diabetes Metabolism Reviews5 citations
Semantic Scholar
Evaluation of the pancreatic B-cell function in the rat after prenatal exposure to streptozotocin or N-nitrosomethylurea.
P. Serradas, M. Giroix, Bernard Portha
1989Diabete & metabolisme3 citations
Semantic Scholar

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