K. Valkenburg

Most-cited papers

1. Targeting the tumour stroma to improve cancer therapy

   K. Valkenburg, A. D. de Groot, K. Pienta

   2018Nature Reviews Clinical Oncology955 citations Open access

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2. Murine Hind Limb Long Bone Dissection and Bone Marrow Isolation

   Sarah R. Amend, K. Valkenburg, K. Pienta

   2016Journal of Visualized Experiments257 citations Open access

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3. Aligning Tumor Mutational Burden (TMB) quantification across diagnostic platforms: Phase 2 of the Friends of Cancer Research TMB Harmonization Project.

   D. M. Vega, Laura M. Yee, L. McShane, P. Williams +46 more

   2021Annals of Oncology161 citations Open access

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4. Wnt/β-catenin Signaling in Normal and Cancer Stem Cells

   K. Valkenburg, Carrie R. Graveel, C. Zylstra-Diegel, Z. Zhong +1 more

   2011Cancers133 citations Open access

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5. Mouse Models of Prostate Cancer

   K. Valkenburg, B. Williams

   2011Prostate Cancer55 citations Open access

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6. AXL is a Putative Tumor Suppressor and Dormancy Regulator in Prostate Cancer

   H. Axelrod, K. Valkenburg, S. Amend, J. Hicks +4 more

   2018Molecular Cancer Research45 citations Open access

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7. Skeletal metastasis: treatments, mouse models, and the Wnt signaling

   K. Valkenburg, Matthew R. Steensma, B. Williams, Z. Zhong

   2013Chinese journal of cancer36 citations Open access

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8. Metastatic Colorectal Cancer Treatment Response Evaluation by Ultra-Deep Sequencing of Cell-Free DNA and Matched White Blood Cells

   I. van 't Erve, J. Medina, A. Leal, E. Papp +15 more

   2022Clinical Cancer Research31 citations Open access

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9. Automated next-generation profiling of genomic alterations in human cancers

   L. Keefer, J. White, Derrick E. Wood, K. Gerding +24 more

   2022Nature Communications23 citations Open access

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10. Murine Prostate Micro-dissection and Surgical Castration.

    K. Valkenburg, Sarah R. Amend, K. Pienta

    2016Journal of Visualized Experiments22 citations Open access

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11. Drug discovery in prostate cancer mouse models

    K. Valkenburg, K. Pienta

    2015Expert Opinion on Drug Discovery19 citations Open access

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12. Activation of Wnt/β-catenin signaling in a subpopulation of murine prostate luminal epithelial cells induces high grade prostate intraepithelial neoplasia

    K. Valkenburg, Xiuping Yu, A. D. De Marzo, Tyler Spiering +2 more

    2014The Prostate19 citations Open access

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13. Concurrent Hepsin overexpression and adenomatous polyposis coli deletion causes invasive prostate carcinoma in mice

    K. Valkenburg, G. Hostetter, B. Williams

    2015The Prostate16 citations

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14. Optimization of prostate cancer cell detection using multiplex tyramide signal amplification

    S. Roy, H. Axelrod, K. Valkenburg, Sarah R. Amend +1 more

    2018Journal of Cellular Biochemistry15 citations Open access

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15. Optimization of Immunofluorescent Detection of Bone Marrow Disseminated Tumor Cells

    H. Axelrod, K. Pienta, K. Valkenburg

    2018Biological Procedures Online15 citations Open access

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16. Next-Generation Sequencing Concordance Analysis of Comprehensive Solid Tumor Profiling between a Centralized Specialty Laboratory and the Decentralized Personal Genome Diagnostics elio Tissue Complete Kitted Solution

    Kristen L. Deak, J. Jackson, K. Valkenburg, L. Keefer +4 more

    2021Journal of Molecular Diagnostics11 citations Open access

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17. Bone marrow niche chemoprotection of metastatic solid tumors mediated by CYP3A4

    G. Ghiaur, K. Valkenburg, Christopher A Esteb, A. Ambinder +3 more

    2023Cancer8 citations Open access

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18. Deletion of tumor suppressors adenomatous polyposis coli and Smad4 in murine luminal epithelial cells causes invasive prostate cancer and loss of androgen receptor expression

    K. Valkenburg, A. D. De Marzo, B. Williams

    2017OncoTarget8 citations Open access

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19. A simple selection-free method for detecting disseminated tumor cells (DTCs) in murine bone marrow

    K. Valkenburg, Sarah R. Amend, J. Verdone, E. E. van der Toom +3 more

    2016OncoTarget6 citations Open access

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20. Validation of the Labcorp Plasma Focus Test to Facilitate Precision Oncology Through Cell-free DNA Genomic Profiling of Solid Tumors.

    Ellen L. Verner, J. Jackson, E. Severson, K. Valkenburg +11 more

    2023Journal of Molecular Diagnostics5 citations Open access

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21. Ten unanswered questions in cancer: "If this is true, what does it imply"?

    Sarah R. Amend, A. D. de Groot, G. Torga, H. Axelrod +4 more

    2018American journal of clinical and experimental urology4 citations

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22. Analytical Validation of the Labcorp Plasma Complete Test, a Cell-free DNA Comprehensive Genomic Profiling Tool for Precision Oncology.

    Ellen L. Verner, J. B. Jackson, Cindy K. Maddox, K. Valkenburg +13 more

    2025Journal of Molecular Diagnostics2 citations Open access

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23. Abstract 72: Comprehensive liquid biopsy profiling enabled by PGDx elio plasmacomplete to facilitate precision oncology through decentralized access to testing

    K. Valkenburg, Vito Caropreso, Jesse M. Fox, Christopher Gault +7 more

    2022Cancer Research2 citations

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24. Origins of Cancer Symposium Report

    Danielle M. Burgenske, K. Valkenburg

    20132 citations Open access

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25. Abstract B049: Validation of the PGDx elio™ plasma complete for comprehensive genomic profiling of solid tumors through liquid biopsy with Epic Sciences

    Cindy K. Maddox, K. Valkenburg, Cesar Nalvarte, Amanda Harvey +8 more

    2024Clinical Cancer Research1 citations

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26. Abstract 3534: Analytical performance of a comprehensive genomic profiling system to detect actionable genetic alterations in NSCLC

    K. Gerding, L. Keefer, Christine McCord, Amy E. Greer +21 more

    2019Molecular and Cellular Biology / Genetics1 citations

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27. Abstract 903: CXCR4 and CXCR7 play distinct and overlapping roles in prostate cancer dissemination to bone

    S. Roy, K. Valkenburg, K. Pienta

    20171 citations

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28. Abstract 365: Mobilizing prostate cancer cells from the endosteal niche by targeting the SDF-1/CXCR4 axis

    K. Valkenburg, K. Pienta

    20151 citations

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29. Abstract 7827: Analytical evaluation of tumor-naive ctDNA molecular response detection through baseline informed comprehensive genomic profiling with matched white blood cell analyses.

    Cindy K. Maddox, Cesar Nalvarte, Amanda Harvey, Vito Caropreso +7 more

    2026Cancer Research0 citations

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30. Abstract 5327: Utilization of urinary cell-free DNA as an informative biomaterial for comprehensive genomic profiling.

    Robert Summersgill, Jesse Fox, Patrick Horn, L. White +9 more

    2026Cancer Research0 citations

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31. Abstract 7284: Clinically significant cancer variants detected by comprehensive genomic profiling test PGDx elio tissue complete

    K. Valkenburg, Jesse Fox, Jennifer B. Jackson, Robert J. Auber +7 more

    2026Cancer Research0 citations

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32. Abstract 3212: Enhancing the detection of circulating tumor DNA by combining Interlace™ global methylation discovery with next-generation sequencing test Labcorp Plasma Complete™

    Kimberly A. Holden, Cindy K. Maddox, Calum Mould, N. Mensah +14 more

    2026Cancer Research0 citations

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33. Abstract 3831: Validation of blood tumor mutation burden in Labcorp Plasma Complete

    Vito Caropreso, K. Valkenburg, Robert Summersgill, Amy Meltzer +10 more

    2026Cancer Research0 citations

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34. Abstract 5356: Leveraging a real-world clinicogenomic database for post-sequencing quality assessment in solid tumor comprehensive genomic profiling (CGP).

    Erin Newburn, R. Previs, Michelle F. Green, Kyle C. Strickland +15 more

    2026Cancer Research0 citations

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35. Abstract 1941: Development of a multiomic approach for the detection of actionable biomarkers in metastatic breast cancer

    Martin Blankfard, David Bourdon, R. Srikrishnan, Alessandra Cunsolo +4 more

    2025Cancer Research0 citations

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36. Abstract 6628: Deep dive into the performance of structural variants reported by PGDx elio plasma focus Dx

    Amy Meltzer, Jesse Fox, K. Valkenburg, Tonya N. Watkins +21 more

    2025Cancer Research0 citations

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37. Abstract 5017: Analytical performance of contrived samples for validation of liquid biopsy assays

    Amanda Harvey, Cindy K. Maddox, Sonomi Dillon, Omar T. Khawar +5 more

    2024Cancer Research0 citations

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38. Analytical validation of the Labcorp Plasma Complete test to enable precision oncology through solid tumor liquid biopsy comprehensive genomic profiling.

    Ellen L. Verner, K. Valkenburg, Cindy K. Maddox, K. Gerding +13 more

    2024Journal of Clinical Oncology0 citations

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39. Abstract B028: Analytical validation of tumor-informed whole genome sequencing analyses for detection of molecular residual disease in solid tumors

    Kaitlin Victor, Andrew Georgiadis, Ellen L. Verner, A. Simmons +15 more

    2024Clinical Cancer Research0 citations

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40. Abstract 5020: Pre-analytical characterization of cell-free DNA to enable liquid biopsy for solid tumors

    Robert Summersgill, Jesse Fox, Jennifer Dickey, Liam Cox +5 more

    2024Cancer Research0 citations

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41. Erratum to "Aligning tumor mutational burden (TMB) quantification across diagnostic platforms: phase II of the Friends of Cancer Research TMB Harmonization Project": [Annals of Oncology 32 (2021) 1626-1636].

    D. M. Vega, L.-M. Yee, L. McShane, P. Williams +46 more

    2023Annals of Oncology0 citations Open access

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42. Abstract 5597: Enhanced detection and classification of cell-free DNA alterations through matched normal analyses with PGDx elioTM plasma complete

    Tonya N. Watkins, Paul M. McGregor, David R. Riley, Tolga Ayazseven +10 more

    2023Cancer Research0 citations

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43. Abstract 5587: Ultra-deep targeted sequencing of cell-free DNA and patient-matched white blood cells for treatment response evaluation in patients with metastatic colorectal cancer

    I. van 't Erve, J. Medina, A. Leal, E. Papp +15 more

    2023Cancer Research0 citations

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44. Cover Image, Volume 120, Number 4, April 2019

    S. Roy, H. Axelrod, K. Valkenburg, Sarah R. Amend +1 more

    2019Journal of Cellular Biochemistry0 citations Open access

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45. Abstract B029: Comparison of a comprehensive NGS profiling assay and conventional molecular testing approaches for detection of clinically relevant alterations in NSCLC

    E. Weingartner, K. Gerding, Gustavo Cerquiera, Christopher R. Gault +17 more

    2019Genomics, Proteomics, and Target Discovery0 citations

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46. Abstract B027: Analytical validation of a 500+ gene comprehensive NGS assay to detect genomic alterations across 35 tumor types

    K. Gerding, K. Valkenburg, C. Oliveras, J. White +9 more

    2019Genomics, Proteomics, and Target Discovery0 citations

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47. Abstract 53: Axl is sufficient but not necessary for disseminated prostate tumor cell dormancy

    H. Axelrod, K. Valkenburg, J. Hicks, A. DeMarzo +1 more

    2018Tumor Biology0 citations

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48. Abstract B070: Epithelial-marker absent and disease-marker specific circulating and disseminated tumor cells are rarely detected in men with localized prostate cancer

    S. Glavaris, H. Chalfin, Chang-Xue Lu, Yan Chen +4 more

    2018Poster Presentations - Proffered Abstracts0 citations

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49. Abstract B083: Disease marker-specific disseminated tumor cells in bone are rare at the time of radical prostatectomy

    Emily A. Caruso, S. Glavaris, H. Chalfin, K. Valkenburg +3 more

    2018Poster Presentations - Proffered Abstracts0 citations

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50. Abstract B026: Axl may support dormancy of disseminated tumor cells by inducing cell clustering and decreasing proliferation of metastatic prostate cancer cells

    H. Axelrod, K. Valkenburg, J. Hicks, A. DeMarzo +1 more

    2018Poster Presentations - Proffered Abstracts0 citations

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