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A. Schätzlein · SciRah

Researcher profile · Semantic Scholar

A. Schätzlein

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A. Schätzlein — researcher profile on SciRah

h-index: 40
Works: 158
Citations: 7,599

Most-cited papers

Nose-to-Brain Delivery
Zian Wang, Guo-Jun Xiong, W. Tsang, A. Schätzlein +1 more
2019Journal of Pharmacology and Experimental Therapeutics164 citations Open access
Semantic Scholar
Amphiphilic poly(L-amino acids) - new materials for drug delivery.
A. Lalatsa, A. Schätzlein, Mariarosa Mazza, T. Le +1 more
2012Journal of Controlled Release151 citations
Semantic Scholar
Strategies to deliver peptide drugs to the brain.
A. Lalatsa, A. Schätzlein, I. Uchegbu
2014Molecular Pharmaceutics141 citations Open access
Semantic Scholar
Enhanced oral absorption of hydrophobic and hydrophilic drugs using quaternary ammonium palmitoyl glycol chitosan nanoparticles.
Adeline Siew, H. Le, Marion Thiovolet, P. Gellert +2 more
2012Molecular Pharmaceutics120 citations
Semantic Scholar
Oral particle uptake and organ targeting drives the activity of amphotericin B nanoparticles.
D. R. Serrano, A. Lalatsa, M. Dea-Ayuela, Pablo E. Bilbao-Ramos +9 more
2015Molecular Pharmaceutics107 citations Open access
Semantic Scholar
Exploring uptake mechanisms of oral nanomedicines using multimodal nonlinear optical microscopy
N. Garrett, A. Lalatsa, I. Uchegbu, A. Schätzlein +1 more
2012Journal of Biophotonics81 citations Open access
Semantic Scholar
A prodrug nanoparticle approach for the oral delivery of a hydrophilic peptide, leucine(5)-enkephalin, to the brain.
A. Lalatsa, Vivian J. Lee, J. Malkinson, M. Zloh +2 more
2012Molecular Pharmaceutics79 citations
Semantic Scholar
Nanofiber-based delivery of therapeutic peptides to the brain.
Mariarosa Mazza, R. Notman, J. Anwar, A. Rodger +10 more
2013ACS Nano71 citations
Semantic Scholar
Nanoparticulate peptide delivery exclusively to the brain produces tolerance free analgesia
L. Godfrey, A. Iannitelli, N. Garrett, J. Moger +7 more
2018Journal of Controlled Release66 citations Open access
Semantic Scholar
Targeting pancreatic cancer with a G-quadruplex ligand.
M. Gunaratnam, M. de la Fuente, Sonja M. Hampel, A. K. Todd +3 more
2011Bioorganic & Medicinal Chemistry65 citations
Semantic Scholar
GC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models.
K. M. Rahman, Paul Jackson, C. James, B. Basu +9 more
2013Journal of Medicinal Chemistry53 citations
Semantic Scholar
SARS-CoV-2 inhibition using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray
K. Pyrć, A. Milewska, E. Duran, Paweł Botwina +11 more
2021Scientific Reports42 citations Open access
Semantic Scholar
Fundamentals of Pharmaceutical Nanoscience
I. Uchegbu, A. Schätzlein, W. Cheng, A. Lalatsa
2013Springer: New York41 citations Open access
Semantic Scholar
Physical characterisation and long-term stability studies on quaternary ammonium palmitoyl glycol chitosan (GCPQ)--a new drug delivery polymer.
K. Chooi, Margarida Isabel Simão Carlos, R. Soundararajan, S. Gaisford +3 more
2014Journal of Pharmacy and Science39 citations
Semantic Scholar
Chitosan amphiphile coating of peptide nanofibres reduces liver uptake and delivers the peptide to the brain on intravenous administration.
A. Lalatsa, A. Schätzlein, Natalie L. Garrett, Julian Moger +5 more
2015Journal of Controlled Release37 citations Open access
Semantic Scholar
Chitosan amphiphiles provide new drug delivery opportunities
I. Uchegbu, M. Carlos, C. McKay, Xueliang Hou +1 more
201437 citations
Semantic Scholar
Inhibition of the hypoxia-inducible factor pathway by a G-quadruplex binding small molecule
S. Welsh, Aaron G. Dale, C. Lombardo, H. Valentine +3 more
2013Scientific Reports37 citations Open access
Semantic Scholar
Lomustine Nanoparticles Enable Both Bone Marrow Sparing and High Brain Drug Levels – A Strategy for Brain Cancer Treatments
F. Fisusi, Adeline Siew, K. Chooi, O. Okubanjo +9 more
2016Pharmaceutical Research36 citations Open access
Semantic Scholar
Plasmonic Nanoparticles for Photothermal Therapy: Benchmarking of Photothermal Properties and Modeling of Heating at Depth in Human Tissues
William H. Skinner, Marzieh Salimi, Laura J. Moran, Ioana Blein-Dezayes +9 more
2025The journal of physical chemistry. C, Nanomaterials and interfaces34 citations Open access
Semantic Scholar
Clustering superparamagnetic iron oxide nanoparticles produces organ-targeted high-contrast magnetic resonance images.
Nicholas J. Hobson, Xian Weng, B. Siow, C. Veiga +4 more
2019Nanomedicine31 citations Open access
Semantic Scholar
Amphotericin B Formulations – The Possibility of Generic Competition
D. R. Serrano, M. P. Ballesteros, A. Schätzlein, J. Torrado +1 more
201331 citations
Semantic Scholar
Surface enhanced deep Raman detection of cancer tumour through 71 mm of heterogeneous tissue
Priyanka Dey, Alexandra Vaideanu, Sara Mosca, M. Salimi +7 more
2022Nanotheranostics30 citations Open access
Semantic Scholar
Efficient synthesis and biological evaluation of proximicins A, B and C.
F. Brucoli, A. Natoli, Preethi Marimuthu, M. T. Borrello +3 more
2012Bioorganic & Medicinal Chemistry30 citations
Semantic Scholar
A nano-enabled cancer-specific ITCH RNAi chemotherapy booster for pancreatic cancer.
M. de la Fuente, Marie-Christine G. Jones, M. Santander-Ortega, Anja Mirenska +3 more
2015Nanomedicine: Nanotechnology, Biology and Medicine25 citations Open access
Semantic Scholar
Particulate levodopa nose-to-brain delivery targets dopamine to the brain with no plasma exposure.
Savvas Dimiou, R. Lopes, I. Kubajewska, Ryan D. Mellor +7 more
2022International journal of pharmaceutics24 citations Open access
Semantic Scholar
A POLYMERIC AQUEOUS TACROLIMUS FORMULATION FOR TOPICAL OCULAR DELIVERY.
Moutaz Y. Badr, Nurul S Abdulrahman, A. Schätzlein, I. Uchegbu
2021International journal of pharmaceutics24 citations Open access
Semantic Scholar
Hydration forces as a tool for the optimization of core–shell nanoparticle vectors for cancer gene therapy
M. Santander-Ortega, M. de la Fuente, M. V. Lozano, M. Bekheet +4 more
201221 citations
Semantic Scholar
The Topical Ocular Delivery of Rapamycin to Posterior Eye Tissues and the Suppression of Retinal Inflammatory Disease.
Moutaz Y. Badr, Abdulrahman A. Halwani, Uchechukwu Odunze, M. Eskandarpour +3 more
2022International journal of pharmaceutics20 citations Open access
Semantic Scholar
Amphotericin B Polymer Nanoparticles Show Efficacy against Candida Species Biofilms
Abdulghani Alakkad, P. Stapleton, C. Schlosser, S. Murdan +3 more
2022Pathogens17 citations Open access
Semantic Scholar
Limiting the level of tertiary amines on polyamines leads to biocompatible nucleic acid vectors.
Margarida Isabel Simão Carlos, Kai-Lu Zheng, N. Garrett, N. Arifin +7 more
2017International journal of pharmaceutics17 citations
Semantic Scholar
Direct in vivo evidence on the mechanism by which nanoparticles facilitate the absorption of a water insoluble, P-gp substrate.
R. Soundararajan, K. Sasaki, L. Godfrey, Uchechukwu Odunze +3 more
2016International journal of pharmaceutics15 citations Open access
Semantic Scholar
The Oral and Intranasal Delivery of Propofol Using Chitosan Amphiphile Nanoparticles
I. Uchegbu, Marie-Christine G. Jones, F. Corrente, L. Godfrey +4 more
201414 citations
Semantic Scholar
Tissue-Engineering the Fibrous Pancreatic Tumour Stroma Capsule in 3D Tumouroids to Demonstrate Paclitaxel Response
Judith Pape, K. Stamati, R. Al Hosni, I. Uchegbu +4 more
2021International Journal of Molecular Sciences13 citations Open access
Semantic Scholar
Down-regulation of GP130 signaling sensitizes bladder cancer to cisplatin by impairing Ku70 DNA repair signaling and promoting apoptosis.
Shanshan He, Gang Li, A. Schätzlein, P. Humphrey +3 more
2021Cellular Signalling13 citations Open access
Semantic Scholar
Hyaluronidase coated MET nanoparticles enhance drug absorption via the subcutaneous route.
R. Soundararajan, George Wang, A. Petkova, I. Uchegbu +1 more
2020Molecular Pharmaceutics13 citations Open access
Semantic Scholar
Nanomedicines in the treatment of brain tumors.
F. Fisusi, A. Schätzlein, I. Uchegbu
2018Nanomedicine13 citations Open access
Semantic Scholar
Triazole-substituted phenylboronic acids as tunable lead inhibitors of KPC-2 antibiotic resistance.
Jingyuan Zhou, P. Stapleton, F. H. Xavier-Júnior, A. Schätzlein +3 more
2022European journal of medicinal chemistry12 citations Open access
Semantic Scholar
Polymeric Micelles for the Enhanced Deposition of Hydrophobic Drugs into Ocular Tissues, without Plasma Exposure
I. Uchegbu, Jan Breznikar, Alessandra Zaffalon, Uchechukwu Odunze +1 more
2021Pharmaceutics12 citations Open access
Semantic Scholar
Gene Targeting to the Cerebral Cortex Following Intranasal Administration of Polyplexes
A. Petkova, I. Kubajewska, Alexandra Vaideanu, A. Schätzlein +1 more
2022Pharmaceutics11 citations Open access
Semantic Scholar
Optimisation of synthetic vector systems for cancer gene therapy - the role of the excess of cationic dendrimer under physiological conditions.
M. Santander-Ortega, M. de la Fuente, M. V. Lozano, M.-L. Tsui +3 more
2014Current Topics in Medicinal Chemistry11 citations
Semantic Scholar
Acetyl-lysine human serum albumin nanoparticles are taken up by CD44 receptors on cancer stem cells and this leads to tumor eradication, without recurrence.
Guo-Jun Xiong, A. Schätzlein, I. Uchegbu
2025Journal of Controlled Release10 citations Open access
Semantic Scholar
High throughput discovery of heteroaromatic-modifying enzymes allows enhancement of novobiocin selectivity.
Sital Patel, M. de la Fuente, S. Ke, Andreia M. R. Guimarães +9 more
2011Chemical Communications10 citations
Semantic Scholar
Increased Efficacy of Oral Fixed-Dose Combination of Amphotericin B and AHCC® Natural Adjuvant against Aspergillosis
Alba Pérez-Cantero, D. R. Serrano, Patricia Navarro-Rodriguez, A. Schätzlein +3 more
2019Pharmaceutics9 citations Open access
Semantic Scholar
The colloidal stability of albumin-based drug delivery systems has a profound effect on tumoricidal activity
Guo-Jun Xiong, Chengwei Jiang, A. Schätzlein, I. Uchegbu
2026Drug Delivery8 citations Open access
Semantic Scholar
Amphiphilic albumin-based nanoparticles designed for the efficient delivery of taxanes.
Guo-Jun Xiong, Sheng-Xi Li, A. Schätzlein, I. Uchegbu
2025International journal of pharmaceutics8 citations Open access
Semantic Scholar
Achieving highly efficient gene transfer to the bladder by increasing the molecular weight of polymer-based nanoparticles.
Gang Li, Shanshan He, A. Schätzlein, R. Weiss +2 more
2021Journal of Controlled Release8 citations Open access
Semantic Scholar
SARS-CoV-2 inhibition in human airway epithelial cells using a mucoadhesive, amphiphilic chitosan that may serve as an anti-viral nasal spray
K. Pyrć, A. Milewska, E. Duran, Paweł Botwina +8 more
2020bioRxiv8 citations Open access
Semantic Scholar
Unusual Enthalpy Driven Self Assembly at Room Temperature with Chitosan Amphiphiles
Uchechukwu Odunze, F. O’Brien, L. Godfrey, A. Schätzlein +1 more
2019Pharmaceutical Nanotechnology8 citations Open access
Semantic Scholar
Dextran-pegylated microparticles for enhanced cellular uptake of hydrophobic drugs.
R. Cassano, Teresa Ferrarelli, A. Schätzlein, I. Uchegbu +1 more
2013European journal of pharmaceutics and biopharmaceutics8 citations
Semantic Scholar
Nanostructures overcoming the blood-brain barrier:physiological considerations and mechanistic issues
A. Lalatsa, A. Schätzlein, I. Uchegbu
20128 citations
Semantic Scholar

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