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A. Mattarei · SciRah

Researcher profile · Semantic Scholar

A. Mattarei

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A. Mattarei — researcher profile on SciRah

h-index: 30
Works: 103
Citations: 2,234

Most-cited papers

Direct Pharmacological Targeting of a Mitochondrial Ion Channel Selectively Kills Tumor Cells In Vivo.
L. Leanza, M. Romio, K. A. Becker, M. Azzolini +22 more
2017Cancer Cell173 citations Open access
Semantic Scholar
Development of mitochondria-targeted derivatives of resveratrol.
L. Biasutto, A. Mattarei, E. Marotta, Alice Bradaschia +4 more
2008Bioorganic & Medicinal Chemistry Letters101 citations
Semantic Scholar
Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction.
Roberto Costa, R. Peruzzo, Magdalena Bachmann, Giulia Dalla Montà +16 more
2019Cell Reports80 citations Open access
Semantic Scholar
REL-1017 (Esmethadone) as Adjunctive Treatment in Patients With Major Depressive Disorder: A Phase 2a Randomized Double-Blind Trial.
M. Fava, S. Stahl, L. Pani, S. De Martin +18 more
2021American Journal of Psychiatry72 citations Open access
Semantic Scholar
A Mitochondriotropic Derivative of Quercetin: A Strategy to Increase the Effectiveness of Polyphenols
A. Mattarei, L. Biasutto, E. Marotta, U. de Marchi +4 more
2008ChemBioChem70 citations
Semantic Scholar
Pharmacokinetics and tissue distribution of pterostilbene in the rat.
M. Azzolini, M. La Spina, A. Mattarei, C. Paradisi +2 more
2014Molecular Nutrition & Food Research68 citations
Semantic Scholar
Acetal derivatives as prodrugs of resveratrol.
A. Mattarei, M. Azzolini, M. Carraro, N. Sassi +3 more
2013Molecular Pharmaceutics68 citations Open access
Semantic Scholar
LETM1-Mediated K+ and Na+ Homeostasis Regulates Mitochondrial Ca2+ Efflux
S. Austin, M. Tavakoli, C. Pfeiffer, J. Seifert +4 more
2017Frontiers in Physiology67 citations Open access
Semantic Scholar
Regioselective O-Derivatization of Quercetin via Ester Intermediates. An Improved Synthesis of Rhamnetin and Development of a New Mitochondriotropic Derivative
A. Mattarei, L. Biasutto, Federico Rastrelli, S. Garbisa +3 more
2010Molecules58 citations Open access
Semantic Scholar
Mitochondria-targeted resveratrol derivatives act as cytotoxic pro-oxidants.
N. Sassi, A. Mattarei, M. Azzolini, P. Bernardi +4 more
2014Current pharmaceutical design57 citations
Semantic Scholar
Resveratrol derivatives as a pharmacological tool
L. Biasutto, A. Mattarei, M. Azzolini, M. La Spina +4 more
2017Annals of the New York Academy of Sciences55 citations
Semantic Scholar
Cytotoxicity of mitochondria-targeted resveratrol derivatives: interactions with respiratory chain complexes and ATP synthase.
N. Sassi, A. Mattarei, M. Azzolini, I. Szabò +3 more
2014Biochimica et Biophysica Acta55 citations Open access
Semantic Scholar
A Synthetic Fluorescent Mitochondria-Targeted Sensor for Ratiometric Imaging of Calcium in Live Cells.
Diana Pendin, R. Norante, André Morais de Nadai, G. Gherardi +7 more
2019Angewandte Chemie50 citations
Semantic Scholar
Targeting the Potassium Channel Kv1.3 Kills Glioblastoma Cells
E. Venturini, L. Leanza, M. Azzolini, Stephanie Kadow +9 more
2017Neurosignals50 citations Open access
Semantic Scholar
Altered MICOS Morphology and Mitochondrial Ion Homeostasis Contribute to Poly(GR) Toxicity Associated with C9-ALS/FTD
Shuangxi Li, Zhi-Hao Wu, Yu Li, Ishaq Tantray +6 more
2020Cell Reports48 citations Open access
Semantic Scholar
Impact of mitochondriotropic quercetin derivatives on mitochondria.
L. Biasutto, N. Sassi, A. Mattarei, E. Marotta +5 more
2010Biochimica et Biophysica Acta46 citations Open access
Semantic Scholar
Amino Acid Carbamates As Prodrugs Of Resveratrol
A. Mattarei, M. Azzolini, M. La Spina, M. Zoratti +2 more
2015Scientific Reports44 citations Open access
Semantic Scholar
Dispersity within Brushes Plays a Major Role in Determining Their Interfacial Properties: The Case of Oligoxazoline-Based Graft Polymers
M. Romio, Benjamin Grob, Lucca Trachsel, A. Mattarei +8 more
2021Journal of the American Chemical Society41 citations Open access
Semantic Scholar
Hsp90 is involved in the entry of clostridial neurotoxins into the cytosol of nerve terminals
Domenico Azarnia Tehran, M. Pirazzini, O. Leka, A. Mattarei +4 more
2017Cellular Microbiology41 citations Open access
Semantic Scholar
Soluble polyphenols: synthesis and bioavailability of 3,4',5-tri(alpha-D-glucose-3-O-succinyl) resveratrol.
L. Biasutto, E. Marotta, Alice Bradaschia, Mauro Fallica +4 more
2009Bioorganic & Medicinal Chemistry Letters41 citations
Semantic Scholar
Cytotoxicity of a mitochondriotropic quercetin derivative: mechanisms.
N. Sassi, L. Biasutto, A. Mattarei, M. Carraro +7 more
2012Biochimica et Biophysica Acta40 citations Open access
Semantic Scholar
Pharmacological modulation of Kv1.3 potassium channel selectively triggers pathological B lymphocyte apoptosis in vivo in a genetic CLL model
F. Severin, A. Urbani, T. Varanita, Magdalena Bachmann +15 more
2022Journal of experimental & clinical cancer research : CR37 citations Open access
Semantic Scholar
Resveratrol and Health: The Starting Point
L. Biasutto, A. Mattarei, M. Zoratti
2012ChemBioChem37 citations
Semantic Scholar
Insight into the mechanism of cytotoxicity of membrane-permeant psoralenic Kv1.3 channel inhibitors by chemical dissection of a novel member of the family
R. Peruzzo, A. Mattarei, M. Azzolini, K. Becker-Flegler +19 more
2020Redox Biology35 citations Open access
Semantic Scholar
New natural amino acid‐bearing prodrugs boost pterostilbene's oral pharmacokinetic and distribution profile
M. Azzolini, A. Mattarei, M. La Spina, M. Fanin +5 more
2017European journal of pharmaceutics and biopharmaceutics34 citations
Semantic Scholar
Improving the efficacy of plant polyphenols.
L. Biasutto, A. Mattarei, N. Sassi, M. Azzolini +3 more
2014Anti-Cancer Agents in Medicinal Chemistry34 citations
Semantic Scholar
pH-Controlled Liposomes for Enhanced Cell Penetration in Tumor Environment.
Michela Barattin, A. Mattarei, A. Balasso, C. Paradisi +6 more
2018ACS Applied Materials and Interfaces33 citations
Semantic Scholar
Pharmacological targeting of the mitochondrial calcium-dependent potassium channel KCa3.1 triggers cell death and reduces tumor growth and metastasis in vivo
Magdalena Bachmann, Andrea Rossa, T. Varanita, B. Fioretti +13 more
2022Cell Death and Disease32 citations Open access
Semantic Scholar
A Novel Inhibitor Prevents the Peripheral Neuroparalysis of Botulinum Neurotoxins
Domenico Azarnia Tehran, G. Zanetti, O. Leka, F. Lista +8 more
2015Scientific Reports32 citations Open access
Semantic Scholar
Pharmacological Comparative Characterization of REL-1017 (Esmethadone-HCl) and Other NMDAR Channel Blockers in Human Heterodimeric N-Methyl-D-Aspartate Receptors
E. Bettini, S. Stahl, S. De Martin, A. Mattarei +14 more
2022Pharmaceuticals30 citations Open access
Semantic Scholar
Novel Mitochondria-Targeted Furocoumarin Derivatives as Possible Anti-Cancer Agents
A. Mattarei, M. Romio, Antonella Managò, M. Zoratti +4 more
2018Frontiers in Oncology30 citations Open access
Semantic Scholar
Esmethadone-HCl (REL-1017): a promising rapid antidepressant
M. Fava, S. Stahl, S. De Martin, A. Mattarei +16 more
2023European Archives of Psychiatry and Clinical Neuroscience27 citations Open access
Semantic Scholar
Defective excitation-contraction coupling and mitochondrial respiration precede mitochondrial Ca2+ accumulation in spinobulbar muscular atrophy skeletal muscle
Caterina Marchioretti, G. Zanetti, M. Pirazzini, G. Gherardi +29 more
2022Nature Communications26 citations Open access
Semantic Scholar
A CXCR4 receptor agonist strongly stimulates axonal regeneration after damage
G. Zanetti, S. Negro, A. Megighian, A. Mattarei +5 more
2019Annals of Clinical and Translational Neurology25 citations Open access
Semantic Scholar
Esmethadone (REL-1017) and Other Uncompetitive NMDAR Channel Blockers May Improve Mood Disorders via Modulation of Synaptic Kinase-Mediated Signaling
S. Stahl, S. De Martin, A. Mattarei, E. Bettini +11 more
2022International Journal of Molecular Sciences23 citations Open access
Semantic Scholar
An Agonist of the CXCR4 Receptor Strongly Promotes Regeneration of Degenerated Motor Axon Terminals
S. Negro, G. Zanetti, A. Mattarei, A. Valentini +9 more
2019Cells23 citations Open access
Semantic Scholar
Synthesis and Evaluation as Prodrugs of Hydrophilic Carbamate Ester Analogues of Resveratrol.
M. Azzolini, A. Mattarei, M. La Spina, E. Marotta +3 more
2015Molecular Pharmaceutics23 citations
Semantic Scholar
New Water-Soluble Carbamate Ester Derivatives of Resveratrol
A. Mattarei, M. Carraro, M. Azzolini, C. Paradisi +2 more
2014Molecules22 citations Open access
Semantic Scholar
Absorption and Metabolism of Resveratrol Carboxyesters and Methanesulfonate by Explanted Rat Intestinal Segments
L. Biasutto, E. Marotta, A. Mattarei, Silvia Beltramello +6 more
2009Cellular Physiology and Biochemistry22 citations
Semantic Scholar
The novel uncompetitive NMDA receptor antagonist esmethadone (REL-1017) has no meaningful abuse potential in recreational drug users
M. Shram, J. Henningfield, G. Apseloff, C. Gorodetzky +17 more
2023Translational Psychiatry21 citations Open access
Semantic Scholar
Inhibition of a Mitochondrial Potassium Channel in Combination with Gemcitabine and Abraxane Drastically Reduces Pancreatic Ductal Adenocarcinoma in an Immunocompetent Orthotopic Murine Model
Wei-Wei Li, G. Wilson, Magdalena Bachmann, Jiang Wang +7 more
2022Cancers21 citations Open access
Semantic Scholar
Regulation of Proliferation by a Mitochondrial Potassium Channel in Pancreatic Ductal Adenocarcinoma Cells
R. Peruzzo, A. Mattarei, M. Romio, C. Paradisi +3 more
2017Frontiers in Oncology21 citations Open access
Semantic Scholar
Strategies to target bioactive molecules to subcellular compartments. Focus on natural compounds.
L. Biasutto, A. Mattarei, M. La Spina, M. Azzolini +3 more
2019European journal of medicinal chemistry20 citations
Semantic Scholar
Synthesis and cellular effects of a mitochondria-targeted inhibitor of the two-pore potassium channel TASK-3.
Magdalena Bachmann, Andrea Rossa, G. Antoniazzi, L. Biasutto +9 more
2020Pharmacological Research19 citations Open access
Semantic Scholar
The Structural Dispersity of Oligoethylene Glycol-Containing Polymer Brushes Determines Their Interfacial Properties.
Carlos Pavón, A. Ongaro, Irene Filipucci, S. Ramakrishna +5 more
2024Journal of the American Chemical Society18 citations Open access
Semantic Scholar
Potential anti‐cancer activity of 7‐O‐pentyl quercetin: Efficient, membrane‐targeted kinase inhibition and pro‐oxidant effect
N. Sassi, A. Mattarei, V. Espina, L. Liotta +3 more
2017Pharmacological Research16 citations
Semantic Scholar
N-Monosubstituted Methoxy-oligo(ethylene glycol) Carbamate Ester Prodrugs of Resveratrol
A. Mattarei, M. Azzolini, M. Zoratti, L. Biasutto +1 more
2015Molecules16 citations Open access
Semantic Scholar
Doxorubicin liposomes cell penetration enhancement and its potential drawbacks for the tumor targeting efficiency.
Hen Popilski, Valeria Feinshtein, Sivan Kleiman, A. Mattarei +3 more
2020International journal of pharmaceutics15 citations
Semantic Scholar
Redox Properties and Cytotoxicity of Synthetic Isomeric Mitochondriotropic Derivatives of the Natural Polyphenol Quercetin
A. Mattarei, N. Sassi, Christian Durante, L. Biasutto +6 more
201115 citations
Semantic Scholar
An Angiopep2-PAPTP Construct Overcomes the Blood-Brain Barrier. New Perspectives against Brain Tumors
Sofia Parrasia, Andrea Rossa, T. Varanita, V. Checchetto +7 more
2021Pharmaceuticals14 citations Open access
Semantic Scholar

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