Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

T. Kinoshita · SciRah

Researcher profile · Semantic Scholar

T. Kinoshita

Share profile

T. Kinoshita — researcher profile on SciRah

h-index: 32
Works: 72
Citations: 4,387

Most-cited papers

Suppression of interleukin‐3‐induced gene expression by a C‐terminal truncated Stat5: role of Stat5 in proliferation.
A. Mui, H. Wakao, T. Kinoshita, T. Kitamura +1 more
1996EMBO Journal445 citations Open access
Semantic Scholar
Fetal liver development requires a paracrine action of oncostatin M through the gp130 signal transducer
Akihide Kamiya, T. Kinoshita, Yoshiaki Ito, Takaaki Matsui +7 more
1999EMBO Journal429 citations Open access
Semantic Scholar
Suppression of apoptotic death in hematopoietic cells by signalling through the IL‐3/GM‐CSF receptors.
T. Kinoshita, T. Yokota, Ken-ichi Arai, A. Miyajima
1995EMBO Journal301 citations Open access
Semantic Scholar
Marked increase of HGF mRNA in non-parenchymal liver cells of rats treated with hepatotoxins.
T. Kinoshita, Kosube Tashiro, Toshikazu Nakamura
1989Biochemical and Biophysical Research Communications - BBRC242 citations
Semantic Scholar
Downregulation of Bim, a Proapoptotic Relative of Bcl-2, Is a Pivotal Step in Cytokine-Initiated Survival Signaling in Murine Hematopoietic Progenitors
T. Shinjyo, R. Kuribara, T. Inukai, H. Hosoi +6 more
2001Molecular and Cellular Biology223 citations Open access
Semantic Scholar
Oncostatin M and hepatocyte growth factor induce hepatic maturation via distinct signaling pathways
A. Kamiya, T. Kinoshita, A. Miyajima
2001FEBS Letters211 citations Open access
Semantic Scholar
Hepatic differentiation induced by oncostatin M attenuates fetal liver hematopoiesis.
T. Kinoshita, Takashi Sekiguchi, Ming-Jiang Xu, Yoshiaki Ito +4 more
1999Proceedings of the National Academy of Sciences of the United States of America174 citations Open access
Semantic Scholar
Regulation of Bcl-2 expression by oncogenic Ras protein in hematopoietic cells.
T. Kinoshita, Takashi Yokota, Ken-ichi Arai, Atsushi Miyajima
1995Oncogene167 citations
Semantic Scholar
Cytokine regulation of liver development.
T. Kinoshita, A. Miyajima
2002Biochimica et Biophysica Acta146 citations Open access
Semantic Scholar
Identification and characterization of "injurin," an inducer of expression of the gene for hepatocyte growth factor.
Kunio Matsumoto, H. Tajima, M. Hamanoue, S. Kohno +2 more
1992Proceedings of the National Academy of Sciences of the United States of America146 citations Open access
Semantic Scholar
Role of Oncostatin M in hematopoiesis and liver development.
Atsushi Miyajima, T. Kinoshita, Minoru Tanaka, Akihide Kamiya +2 more
2000Cytokine & growth factor reviews143 citations
Semantic Scholar
Possible endocrine control by hepatocyte growth factor of liver regeneration after partial hepatectomy.
T. Kinoshita, S. Hirao, Kunio Matsumoto, Toshikazu Nakamura
1991Biochemical and Biophysical Research Communications - BBRC143 citations
Semantic Scholar
Raf/MAPK and rapamycin-sensitive pathways mediate the anti-apoptotic function of p21Ras in IL-3-dependent hematopoietic cells
T. Kinoshita, M. Shirouzu, A. Kamiya, K. Hashimoto +2 more
1997Oncogene122 citations Open access
Semantic Scholar
Requirement of the Caspase-3/CPP32 Protease Cascade for Apoptotic Death following Cytokine Deprivation in Hematopoietic Cells*
T. Ohta, T. Kinoshita, M. Naito, T. Nozaki +3 more
1997Journal of Biological Chemistry109 citations Open access
Semantic Scholar
Maturation of fetal hepatocytes in vitro by extracellular matrices and oncostatin M: Induction of tryptophan oxygenase
A. Kamiya, N. Kojima, T. Kinoshita, Y. Sakai +1 more
2002Hepatology107 citations
Semantic Scholar
K‐Ras mediates cytokine‐induced formation of E‐cadherin‐based adherens junctions during liver development
Takaaki Matsui, T. Kinoshita, Y. Morikawa, K. Tohya +4 more
2002EMBO Journal92 citations Open access
Semantic Scholar
Hepatoma‐derived growth factor is highly expressed in developing liver and promotes fetal hepatocyte proliferation
H. Enomoto, Kenya Yoshida, Yoshihiko Kishima, T. Kinoshita +4 more
2002Hepatology92 citations
Semantic Scholar
Two Distinct Interleukin-3-Mediated Signal Pathways, Ras-NFIL3 (E4BP4) and Bcl-xL, Regulate the Survival of Murine Pro-B Lymphocytes
R. Kuribara, T. Kinoshita, A. Miyajima, T. Shinjyo +5 more
1999Molecular and Cellular Biology80 citations Open access
Semantic Scholar
Ibrutinib Inhibits ERBB Receptor Tyrosine Kinases and HER2-Amplified Breast Cancer Cell Growth
Jun Chen, T. Kinoshita, J. Sukbuntherng, B. Chang +1 more
2016Molecular Cancer Therapeutics78 citations
Semantic Scholar
STAT3 Down-regulates the Expression of Cyclin D during Liver Development*
Takaaki Matsui, T. Kinoshita, T. Hirano, T. Yokota +1 more
2002Journal of Biological Chemistry72 citations Open access
Semantic Scholar
Preclinical characterization of Aurora kinase inhibitor R763/AS703569 identified through an image-based phenotypic screen
John R. McLaughlin, V. Markovtsov, Hui Li, Steve T. Wong +30 more
2009Journal of Cancer Research and Clinical Oncology67 citations Open access
Semantic Scholar
Cultivation of aorta-gonad-mesonephros-derived hematopoietic stem cells in the fetal liver microenvironment amplifies long-term repopulating activity and enhances engraftment to the bone marrow.
M. Takeuchi, Takashi Sekiguchi, T. Hara, T. Kinoshita +1 more
2002Blood67 citations Open access
Semantic Scholar
AMPK Activation through Mitochondrial Regulation Results in Increased Substrate Oxidation and Improved Metabolic Parameters in Models of Diabetes
Y. Jenkins, Tianduo Sun, V. Markovtsov, M. Foretz +35 more
2013PLoS ONE58 citations Open access
Semantic Scholar
Enhanced In Vitro Maturation of Fetal Mouse Liver Cells with Oncostatin M, Nicotinamide, and Dimethyl Sulfoxide
Yasuyuki Sakai, Jin-Lan Jiang, N. Kojima, T. Kinoshita +1 more
2002Cell Transplantation57 citations Open access
Semantic Scholar
Retroviral gene transfer of signaling molecules into murine fetal hepatocytes defines distinct roles for the STAT3 and ras pathways during hepatic development
Yoshiaki Ito, Takaaki Matsui, A. Kamiya, T. Kinoshita +1 more
2000Hepatology51 citations Open access
Semantic Scholar
Cell density-dependent regulation of hepatic development by a gp130-independent pathway.
N. Kojima, T. Kinoshita, Akihide Kamiya, Koji Nakamura +3 more
2000Biochemical and Biophysical Research Communications - BBRC48 citations
Semantic Scholar
Inhibition of Janus kinase signaling during controlled mechanical ventilation prevents ventilation-induced diaphragm dysfunction
Ira J. Smith, Guillermo L. Godinez, Baljit Singh, K. McCaughey +30 more
2014The FASEB Journal46 citations Open access
Semantic Scholar
Cytokine signaling for proliferation, survival, and death in hematopoietic cells.
Atsushi Miyajima, Yoshiaki Ito, T. Kinoshita
1999International journal of hematology45 citations
Semantic Scholar
The effect of Bruton's tyrosine kinase (BTK) inhibitors on collagen‐induced platelet aggregation, BTK, and tyrosine kinase expressed in hepatocellular carcinoma (TEC)
Jun Chen, T. Kinoshita, T. Gururaja, J. Sukbuntherng +5 more
2018European Journal of Haematology43 citations Open access
Semantic Scholar
A Class of Small Molecules that Inhibit TNFα-Induced Survival and Death Pathways via Prevention of Interactions between TNFαRI, TRADD, and RIP1
T. Gururaja, Stephanie Yung, Rong-Xian Ding, Jia-Ning Huang +8 more
200743 citations Open access
Semantic Scholar
Developmental changes in hepatocyte growth factor mRNA and its receptor in rat liver, kidney and lung.
Masako Kagoshima, T. Kinoshita, Kunio Matsumoto, Toshikazu Nakamura
1992European Journal of Biochemistry42 citations Open access
Semantic Scholar
Cultivation of Fetal Liver Cells in a Three-Dimensional Poly-L-Lactic Acid Scaffold in the Presence of Oncostatin M
Jin-Lan Jiang, N. Kojima, T. Kinoshita, A. Miyajima +2 more
2002Cell Transplantation35 citations Open access
Semantic Scholar
Relative Selectivity of Covalent Inhibitors Requires Assessment of Inactivation Kinetics and Cellular Occupancy: A Case Study of Ibrutinib and Acalabrutinib
M. Hopper, T. Gururaja, T. Kinoshita, J. Dean +2 more
2019Journal of Pharmacology and Experimental Therapeutics32 citations Open access
Semantic Scholar
Selective cytotoxicity and stereochemistry of aspochalasin D.
Taijiro Tomikawa, K. Shin-ya, T. Kinoshita, Atsushi Miyajima +2 more
2001Journal of antibiotics (Tokyo. 1968)25 citations
Semantic Scholar
Hepatoma-derived growth factor is highly expressed in developing liver and promotes fetal hepatocyte proliferation.
H. Enomoto, Kenya Yoshida, Yoshihiko Kishima, T. Kinoshita +4 more
200222 citations
Semantic Scholar
Rasfonin, a new apoptosis inducer in ras-dependent cells from Talaromyces sp.
Taijiro Tomikawa, K. Shin-ya, K. Furihata, T. Kinoshita +3 more
2000Journal of antibiotics (Tokyo. 1968)21 citations Open access
Semantic Scholar
A class of small molecules that inhibit TNFalpha-induced survival and death pathways via prevention of interactions between TNFalphaRI, TRADD, and RIP1.
T. Gururaja, Stephanie Yung, Rong-Xian Ding, Jia-Ning Huang +8 more
2007Chemistry and Biology20 citations
Semantic Scholar
R-253 Disrupts Microtubule Networks in Multiple Tumor Cell Lines
T. Gururaja, D. Goff, T. Kinoshita, E. Goldstein +9 more
2006Clinical Cancer Research20 citations Open access
Semantic Scholar
Signal transduction by the GM-CSF, IL-3 and IL-5 receptors.
A. Miyajima, T. Kinoshita, H. Wakao, Takahiko Hara +4 more
1997Leukemia18 citations
Semantic Scholar
Function of the common beta subunit of the GM-CSF/IL-3/IL-5 receptors.
A. Mui, Akihiko Muto, K. Sakamaki, N. Sato +5 more
1994Advances in Experimental Medicine and Biology14 citations
Semantic Scholar
Effects of ibrutinib on in vitro platelet aggregation in blood samples from healthy donors and donors with platelet dysfunction
J. Ninomoto, A. Mokatrin, T. Kinoshita, Carol Marimpietri +5 more
2020Hematology13 citations Open access
Semantic Scholar
Ammocidin, a new apoptosis inducer in Ras-dependent cells from Saccharothrix sp. I. Production, isolation and biological activity.
R. Murakami, Taijiro Tomikawa, K. Shin-ya, J. Shinozaki +5 more
2001Journal of antibiotics (Tokyo. 1968)13 citations Open access
Semantic Scholar
Oncostatin M suppresses generation of lymphoid progenitors in fetal liver by inhibiting the hepatic microenvironment.
T. Kinoshita, K. Nagata, N. Sorimachi, H. Karasuyama +2 more
2001Experimental Hematology12 citations Open access
Semantic Scholar
Targeting IRAK3 for Degradation to Enhance IL-12 Pro-inflammatory Cytokine Production.
Ann M. Rowley, B. Brown, M. Stofega, Hana Y. Hoh +11 more
2022ACS Chemical Biology9 citations
Semantic Scholar
Cultivation and induction of fetal liver cells in poly-l-lactic acid scaffold
Jin-Lan Jiang, N. Kojima, T. Kinoshita, A. Miyajima +2 more
20049 citations
Semantic Scholar
Kinetic Catalytic Inhibition and Cell-Based Analysis, Not Just Target Binding, Are Required to Assess Kinase Selectivity of Covalent Inhibitors: Comparable BTK vs TEC Selectivity Profile for Ibrutinib and Acalabrutinib
M. Hopper, T. Gururaja, T. Kinoshita, J. Dean +2 more
2018Blood7 citations Open access
Semantic Scholar
Noninvasive Imaging of In Vivo MuRF1 Expression during Muscle Atrophy
Wei Li, Mark D. Claypool, Annabelle M. Friera, John R. McLaughlin +8 more
2014PLoS ONE5 citations Open access
Semantic Scholar
The Hematopoietic Cytokine Receptors
Anne-Marie O'Farrell, T. Kinoshita, A. Miyajima
19965 citations
Semantic Scholar
113-LB: Oral Menin Inhibitor, BMF-219, Displays a Significant and Durable Reduction in HbA1c in a Type 2 Diabetes Mellitus Rat Model
Priyanka Somanath, Sanchita Mourya, Wei-Qun Li, Tenley C. Archer +7 more
2022Diabetes3 citations
Semantic Scholar
Novel Irreversible Menin Inhibitor, BMF-219, Shows Potent Single Agent Activity in Clinically Relevant DLBCL Cells
Priyanka Somanath, D. Lu, B. Law, Tenley C. Archer +4 more
2021Blood3 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

A. Miyajima×20
Invite
A. Miyajima — researcher profile on SciRah
T. Gururaja×10
Invite
T. Gururaja — researcher profile on SciRah
Atsushi Miyajima×8
Invite
Atsushi Miyajima — researcher profile on SciRah
John R. McLaughlin×6
Invite
John R. McLaughlin — researcher profile on SciRah

×6

Invite

Rajinder Singh — researcher profile on SciRah

Invite

D. Payan — researcher profile on SciRah

Invite

A. Kamiya — researcher profile on SciRah

Invite

N. Kojima — researcher profile on SciRah

Stephanie Yung×5

Invite

Stephanie Yung — researcher profile on SciRah

Akihide Kamiya×4

Invite

Akihide Kamiya — researcher profile on SciRah

Yoshiaki Ito×4

Invite

Yoshiaki Ito — researcher profile on SciRah

Takaaki Matsui×4

Invite

Takaaki Matsui — researcher profile on SciRah