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N. Smirnova · SciRah

Researcher profile · Semantic Scholar

N. Smirnova

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N. Smirnova — researcher profile on SciRah

h-index: 18
Works: 35
Citations: 1,579

Most-cited papers

The mouse X chromosome is enriched for sex-biased genes not subject to selection by meiotic sex chromosome inactivation
P. Khil, N. Smirnova, Peter J. Romanienko, R. Camerini-Otero
2004Nature Genetics314 citations
Semantic Scholar
Targeting Nrf2-Mediated Gene Transcription by Extremely Potent Synthetic Triterpenoids Attenuate Dopaminergic Neurotoxicity in the MPTP Mouse Model of Parkinson's Disease
N. Kaidery, Rebecca Banerjee, Li-Chuan Yang, N. Smirnova +10 more
2013Antioxidants and Redox Signaling166 citations Open access
Semantic Scholar
Controlled enzymatic production of astrocytic hydrogen peroxide protects neurons from oxidative stress via an Nrf2-independent pathway
R. Haskew-Layton, Jimmy B. Payappilly, N. Smirnova, Thong C. Ma +12 more
2010Proceedings of the National Academy of Sciences of the United States of America157 citations Open access
Semantic Scholar
Hypoxia inducible factor prolyl hydroxylases as targets for neuroprotection by “antioxidant” metal chelators: from ferroptosis to stroke
R. Speer, Saravanan S. Karuppagounder, M. Basso, Sama F. Sleiman +6 more
2013Free Radical Biology & Medicine142 citations Open access
Semantic Scholar
Inhibition of 12/15-lipoxygenase as therapeutic strategy to treat stroke
K. Yiğitkanlı, A. Pekcec, H. Karatas, S. Pallast +10 more
2012Annals of Neurology121 citations Open access
Semantic Scholar
Development of Neh2-Luciferase Reporter and Its Application for High Throughput Screening and Real-Time Monitoring of Nrf2 Activators
N. Smirnova, R. Haskew-Layton, M. Basso, D. Hushpulian +8 more
2011Chemistry and Biology105 citations Open access
Semantic Scholar
Harnessing hypoxic adaptation to prevent, treat, and repair stroke
R. Ratan, A. Siddiq, N. Smirnova, Ksenia Karpisheva +12 more
2007Journal of molecular medicine87 citations Open access
Semantic Scholar
Utilization of an In Vivo Reporter for High Throughput Identification of Branched Small Molecule Regulators of Hypoxic Adaptation
N. Smirnova, Ilay Rakhman, N. Moroz, M. Basso +7 more
2010Chemistry and Biology82 citations Open access
Semantic Scholar
Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy
Victor Tapias, Shari Jainuddin, M. Ahuja, Cliona Stack +17 more
2018Human Molecular Genetics79 citations Open access
Semantic Scholar
Small Molecule Activation of Adaptive Gene Expression
R. Ratan, A. Siddiq, L. Aminova, Brett C. Langley +19 more
2008Annals of the New York Academy of Sciences39 citations Open access
Semantic Scholar
Gene expression profiles of Spo11-/- mouse testes with spermatocytes arrested in meiotic prophase I.
N. Smirnova, Peter J. Romanienko, P. Khil, R. Camerini-Otero
2006Reproduction36 citations Open access
Semantic Scholar
Isolation and Characterization of Bacillus subtilis sigB Operon Mutations That Suppress the Loss of the Negative Regulator RsbX
N. Smirnova, Janelle M. Scott, U. Voelker, W. Haldenwang
1998Journal of Bacteriology36 citations Open access
Semantic Scholar
L-ascorbic acid: A true substrate for HIF prolyl hydroxylase?
A. Osipyants, A. Poloznikov, N. Smirnova, D. Hushpulian +9 more
2017Biochimie28 citations Open access
Semantic Scholar
Bioactive Flavonoids and Catechols as Hif1 and Nrf2 Protein Stabilizers - Implications for Parkinson’s Disease
N. Smirnova, N. Kaidery, D. Hushpulian, Ilay Rakhman +11 more
2016Aging and Disease27 citations Open access
Semantic Scholar
Catalytic mechanism and substrate specificity of HIF prolyl hydroxylases
N. Smirnova, D. Hushpulian, R. Speer, I. Gaisina +2 more
2012Biochemistry (Moscow)27 citations
Semantic Scholar
Engineered Fatty Acid Biosynthesis inStreptomyces by Altered Catalytic Function of β-Ketoacyl-Acyl Carrier Protein Synthase III
N. Smirnova, K. Reynolds
2001Journal of Bacteriology24 citations Open access
Semantic Scholar
Structure-activity relationship for branched oxyquinoline HIF activators: Effect of modifications to phenylacetamide "tail".
A. Poloznikov, A. A. Zakhariants, S. Nikulin, N. Smirnova +5 more
2017Biochimie19 citations
Semantic Scholar
In vitro Ischemia Suppresses Hypoxic Induction of Hypoxia Inducible Factor-1α by Inhibition of Synthesis and Not Enhanced Degradation
Saravanan S. Karuppagounder, M. Basso, Sama F. Sleiman, Thong C. Ma +4 more
2013Journal of Neuroscience Research19 citations Open access
Semantic Scholar
A Bacillus-specific factor is needed to trigger the stress-activated phosphatase/kinase cascade of sigmaB induction.
J. M. Scott, N. Smirnova, W. Haldenwang
1999Biochemical and Biophysical Research Communications - BBRC15 citations
Semantic Scholar
ABacillus-Specific Factor Is Needed to Trigger the Stress-Activated Phosphatase/Kinase Cascade of ςBInduction
Janelle M. Scott, N. Smirnova, W. Haldenwang
199915 citations
Semantic Scholar
Enzyme–substrate reporters for evaluation of substrate specificity of HIF prolyl hydroxylase isoforms
A. Osipyants, N. Smirnova, A. Khristichenko, D. Hushpulian +6 more
2017Biochemistry (Moscow)14 citations
Semantic Scholar
Structural optimization of adaptaquin, a HIF prolyl hydroxylase inhibitor
A. A. Poloznikov, A. Khristichenko, N. Smirnova, D. Hushpulian +4 more
2019Russian chemical bulletin8 citations
Semantic Scholar
HIF2 ODD-luciferase reporter: the most sensitive assay for HIF prolyl hydroxylase inhibitors
N. Smirnova, A. Osipyants, A. Khristichenko, D. Hushpulian +6 more
2018Russian chemical bulletin4 citations
Semantic Scholar
Antihypoxic activity of adaptaquin enantiomers
Irina N. Gaisina, A. Khristichenko, A. Gaisin, N. Smirnova +2 more
2018Russian chemical bulletin4 citations
Semantic Scholar
Metal Ions as Activators of Hypoxia Inducible Factor
A. Osipyants, N. Smirnova, A. Khristichenko, S. Nikulin +4 more
2018Moscow University Chemistry Bulletin4 citations
Semantic Scholar
Antioxidant and antihypoxic properties of neuroprotective drugs
A. A. Poloznikov, N. Smirnova, A. Khristichenko, D. Hushpulian +4 more
2016Russian chemical bulletin3 citations
Semantic Scholar
Quantitative Analysis of Cell-Based Luciferase Fusion Reporters
A. Khristichenko, A. Poloznikov, D. Hushpulian, N. Smirnova +4 more
2019Moscow University Chemistry Bulletin2 citations
Semantic Scholar
Optimization of Neh2-Luc Reporter for Screening of Activators of Antioxidant Program
Yu. Khristichenko, D. Hushpulian, N. Smirnova, A. A. Zakhariants +4 more
2020Moscow University Chemistry Bulletin1 citations
Semantic Scholar
Reactivation of HIF prolyl hydroxylase 2 from E.coli inclusion bodies
D. Hushpulian, A. A. Zakharyants, N. Smirnova, A. A. Poloznikov +3 more
2015Russian chemical bulletin1 citations
Semantic Scholar
Novel Approach to High Throughput Screening for Activators of Transcription Factors
N. Smirnova, D. Hushpulian, R. Ratan, I. Gazaryan
20111 citations Open access
Semantic Scholar
Continuous assay to monitor reactivation of various oxygenases from E. coli inclusion bodies
A. A. Zakharyants, D. Hushpulian, N. Smirnova, A. Poloznikov +3 more
20150 citations
Semantic Scholar
MICAL—methionine sulfoxide reductase couple: a new target for the development of neuroprotective strategies
A. A. Zakhariants, A. A. Poloznikov, N. Smirnova, V. Tishkov +1 more
2014Russian chemical bulletin0 citations
Semantic Scholar
Refolding of FAD-monooxygenase domain of MICAL from inclusion bodies
A. A. Zakharyants, A. Poloznikov, N. Smirnova, T. Chubar +2 more
20130 citations
Semantic Scholar
Therapeutic modulation of adaptive responses to oxidative stress in astrocytes: Nrf-2 dependent and Nrf-2 independent mechanisms
R. Ratan, R. Haskew-Layton, M. Basso, R. Speer +3 more
20120 citations
Semantic Scholar
Abstract 3494: LOXblock-1 Provides Efficient, Specific, And Long-lasting Neuroprotection Against Transient Focal Ischemia In Mice By Inhibiting 12/15-Lipoxygenase
K. Yiğitkanlı, A. Pekcec, S. Pallast, E. Mandeville +8 more
2012Stroke0 citations
Semantic Scholar

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