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Pyry I. Toivanen · SciRah

Researcher profile · Semantic Scholar

Pyry I. Toivanen

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Pyry I. Toivanen — researcher profile on SciRah

h-index: 14
Works: 27
Citations: 639

Most-cited papers

Adenoviral intramyocardial VEGF-DΔNΔC gene transfer increases myocardial perfusion reserve in refractory angina patients: a phase I/IIa study with 1-year follow-up
J. Hartikainen, I. Hassinen, A. Hedman, A. Kivelä +11 more
2017European Heart Journal132 citations Open access
Semantic Scholar
Structural determinants of vascular endothelial growth factor-D receptor binding and specificity.
Veli-Matti Leppänen, M. Jeltsch, A. Anisimov, D. Tvorogov +6 more
2011Blood106 citations
Semantic Scholar
Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice.
Hanna Sallinen, M. Anttila, J. Narvainen, J. Koponen +8 more
2009Molecular Therapy53 citations Open access
Semantic Scholar
A multipurpose vector system for the screening of libraries in bacteria, insect and mammalian cells and expression in vivo
O. Laitinen, Kari J. Airenne, V. Hytönen, E. Peltomaa +10 more
2005Nucleic Acids Research48 citations Open access
Semantic Scholar
Vascular Endothelial Growth Factor (VEGF)-D Stimulates VEGF-A, Stanniocalcin-1, and Neuropilin-2 and Has Potent Angiogenic Effects
S. Jauhiainen, Sanna-Kaisa Häkkinen, Pyry I. Toivanen, Suvi E. Heinonen +5 more
2011Arteriosclerosis, Thrombosis and Vascular Biology41 citations
Semantic Scholar
Novel Vascular Endothelial Growth Factor D Variants with Increased Biological Activity*
Pyry I. Toivanen, Tiina Nieminen, L. Viitanen, A. Alitalo +9 more
2009Journal of Biological Chemistry39 citations Open access
Semantic Scholar
A laboratory-scale device for the straightforward production of uniform, small sized cell microcapsules with long-term cell viability.
Leena-Stiina Kontturi, M. Yliperttula, Pyry I. Toivanen, Antti Määttä +2 more
2011Journal of Controlled Release38 citations
Semantic Scholar
Differential regulation of angiogenic cellular processes and claudin-5 by histamine and VEGF via PI3K-signaling, transcription factor SNAI2 and interleukin-8
J. Laakkonen, Jari P. Lappalainen, T. Theelen, Pyry I. Toivanen +5 more
2016Angiogenesis37 citations Open access
Semantic Scholar
A 96-well format for a high-throughput baculovirus generation, fast titering and recombinant protein production in insect and mammalian cells
Hanna-Riikka Kärkkäinen, Hanna P. Lesch, Antti Määttä, Pyry I. Toivanen +5 more
2009BMC Research Notes28 citations Open access
Semantic Scholar
The impact of the receptor binding profiles of the vascular endothelial growth factors on their angiogenic features.
Tiina Nieminen, Pyry I. Toivanen, Nina Rintanen, T. Heikura +5 more
2014Biochimica et Biophysica Acta27 citations
Semantic Scholar
Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function
S. Jauhiainen, J. Laakkonen, K. Ketola, Pyry I. Toivanen +5 more
2019Frontiers in Physiology19 citations Open access
Semantic Scholar
Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling
Pyry I. Toivanen, Tiina Nieminen, J. Laakkonen, T. Heikura +2 more
2017Scientific Reports14 citations Open access
Semantic Scholar
Slit2 modifies VEGF-induced angiogenic responses in rabbit skeletal muscle via reduced eNOS activity.
Tiina Nieminen, Pyry I. Toivanen, J. Laakkonen, T. Heikura +3 more
2015Cardiovascular Research14 citations Open access
Semantic Scholar
Preclinical Safety, Toxicology, and Biodistribution Study of Adenoviral Gene Therapy with sVEGFR-2 and sVEGFR-3 Combined with Chemotherapy for Ovarian Cancer
Laura Tuppurainen, Hanna Sallinen, Emmi Kokki, J. Koponen +9 more
2013Human Gene Therapy Clinical Development14 citations
Semantic Scholar
Adenoviral VEGF-B186R127S gene transfer induces angiogenesis and improves perfusion in ischemic heart
H. Korpela, Olli-Pekka Hätinen, Tiina Nieminen, Rahul Mallick +7 more
2021iScience10 citations Open access
Semantic Scholar
Antiangiogenic AAV2 gene therapy with a truncated form of soluble VEGFR-2 reduces the growth of choroidal neovascularization in mice after intravitreal injection.
Jooseppi Puranen, Sanna Koponen, Tiina Nieminen, Iiris Kanerva +5 more
2022Experimental Eye Research9 citations Open access
Semantic Scholar
Novel Designed Proteolytically Resistant VEGF-B186R127S Promotes Angiogenesis in Mouse Heart by Recruiting Endothelial Progenitor Cells
Rahul Mallick, E. Gurzeler, Pyry I. Toivanen, Tiina Nieminen +1 more
2022Frontiers in Bioengineering and Biotechnology7 citations Open access
Semantic Scholar
Abstract 11987: Adenoviral Intramyocardial VEGF-D Gene Transfer Increases Myocardial Perfusion in Refractory Angina Patients
I. Hassinen, J. Hartikainen, A. Hedman, A. Kivelä +8 more
20156 citations
Semantic Scholar
Low dose Adenoviral Vammin gene transfer induces myocardial angiogenesis and increases left ventricular ejection fraction in ischemic porcine heart
N. Järveläinen, P. Halonen, J. Nurro, A. Kuivanen +10 more
2024Scientific Reports0 citations Open access
Semantic Scholar
Snake venom VEGF Vammin induces a highly efficient angiogenic response in skeletal muscle via VEGFR-2/NRP specific signaling
Pyry I. Toivanen, Tiina Nieminen, J. Laakkonen, T. Heikura +2 more
2017Scientific Reports0 citations Open access
Semantic Scholar
Gene transfer using vammin induces robust angiogenesis and increases ejection fraction in ischemic porcine myocardium
P. Halonen, J. Nurro, A. Kuivanen, Pyry I. Toivanen +5 more
20130 citations Open access
Semantic Scholar
Crystal structure of vascular endothelial growth factor D
Veli-Matti Leppänen, M. Jeltsch, A. Anisimov, D. Tvorogov +6 more
20110 citations
Semantic Scholar
Baculovirus-mediated EGFP (pBVboostFG + EGFP) gene transfer in rat brain
Kulomaa, Olli H. Laitinen Seppo Ylä Herttuala, Kari J. Airenne, V. Hytönen +10 more
20110 citations
Semantic Scholar
The excitation and emission spectra (black) of the three fluorescent protein mutants identified by l
Kulomaa, Olli H. Laitinen Seppo Ylä Herttuala, Kari J. Airenne, V. Hytönen +10 more
20110 citations
Semantic Scholar
binding and specificity Structural determinants of vascular endothelial growth factor-D receptor
Pyry I. Toivanen, S. Yla-Herttuala, K. Ballmer-Hofer, K. Alitalo +5 more
20110 citations
Semantic Scholar
Homology modeling of VEGF-D as a basis for structural and functional analysis
L. Viitanen, Pyry I. Toivanen, Tiina Nieminen, A. Alitalo +9 more
20090 citations Open access
Semantic Scholar
758. A Multipurpose Vector System for the Simultaneous Screening of Libraries in Bacteria, Insect and Mammalian Cells and Expression In Vivo
O. Laitinen, Kari J. Airenne, V. Hytönen, E. Peltomaa +10 more
2005Molecular Therapy0 citations Open access
Semantic Scholar
758. A Multipurpose Vector System for the Simultaneous Screening of Libraries in Bacteria, Insect and Mammalian Cells and Expression
O. Laitinen, Kari J. Airenne, V. Hytönen, E. Peltomaa +10 more
20050 citations
Semantic Scholar

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