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A. Arnold · SciRah

Researcher profile · Semantic Scholar

A. Arnold

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A. Arnold — researcher profile on SciRah

h-index: 25
Works: 58
Citations: 5,926

Most-cited papers

Effects of long-term vitamin E supplementation on cardiovascular events and cancer: a randomized controlled trial.
E. Lonn, J. Bosch, S. Yusuf, P. Sheridan +7 more
2005Journal of the American Medical Association (JAMA)1,217 citations Open access
Semantic Scholar
Chemotherapy can prolong survival in patients with advanced non-small-cell lung cancer--report of a Canadian multicenter randomized trial.
E. Rapp, J. Pater, A. Willan, Y. Cormier +6 more
1988Journal of Clinical Oncology740 citations
Semantic Scholar
Importance of timing for thoracic irradiation in the combined modality treatment of limited-stage small-cell lung cancer. The National Cancer Institute of Canada Clinical Trials Group.
N. Murray, P. Coy, J. Pater, I. Hodson +6 more
1993Journal of Clinical Oncology699 citations
Semantic Scholar
Randomized trial of intensive cyclophosphamide, epirubicin, and fluorouracil chemotherapy compared with cyclophosphamide, methotrexate, and fluorouracil in premenopausal women with node-positive breast cancer. National Cancer Institute of Canada Clinical Trials Group.
M. Levine, V. Bramwell, K. Pritchard, B. Norris +14 more
1998Journal of Clinical Oncology618 citations
Semantic Scholar
Safety of treatment of metastatic breast cancer with trastuzumab beyond disease progression.
D. Tripathy, D. Slamon, M. Cobleigh, A. Arnold +4 more
2004Journal of Clinical Oncology301 citations
Semantic Scholar
Pharmacokinetics, safety, and efficacy of trastuzumab administered every three weeks in combination with paclitaxel.
B. Leyland-Jones, K. Gelmon, J. Ayoub, A. Arnold +3 more
2003Journal of Clinical Oncology290 citations
Semantic Scholar
Randomized, double-blind trial of carboplatin and paclitaxel with either daily oral cediranib or placebo in advanced non-small-cell lung cancer: NCIC clinical trials group BR24 study.
G. Goss, A. Arnold, F. Shepherd, M. Dediu +16 more
2010Journal of Clinical Oncology221 citations
Semantic Scholar
Phase II study of vandetanib or placebo in small-cell lung cancer patients after complete or partial response to induction chemotherapy with or without radiation therapy: National Cancer Institute of Canada Clinical Trials Group Study BR.20.
A. Arnold, L. Seymour, M. Smylie, K. Ding +14 more
2007Journal of Clinical Oncology199 citations
Semantic Scholar
The supportive care needs of newly diagnosed cancer patients attending a regional cancer center
T. Whelan, E. Mohide, A. Willan, A. Arnold +4 more
1997Cancer176 citations Open access
Semantic Scholar
Randomized phase III study of matrix metalloproteinase inhibitor BMS-275291 in combination with paclitaxel and carboplatin in advanced non-small-cell lung cancer: National Cancer Institute of Canada-Clinical Trials Group Study BR.18.
N. Leighl, L. Paz-Ares, J. Douillard, C. Peschel +15 more
2005Journal of Clinical Oncology175 citations
Semantic Scholar
Tumor cavitation: impact on objective response evaluation in trials of angiogenesis inhibitors in non-small-cell lung cancer.
S. Crabb, D. Patsios, E. Sauerbrei, P. Ellis +7 more
2009Journal of Clinical Oncology162 citations
Semantic Scholar
Quality of life in a randomized trial of group psychosocial support in metastatic breast cancer: overall effects of the intervention and an exploration of missing data.
L. Bordeleau, J. Szalai, M. Ennis, M. Leszcz +11 more
2003Journal of Clinical Oncology151 citations
Semantic Scholar
Phase II study of pemetrexed disodium, a multitargeted antifolate, and cisplatin as first‐line therapy in patients with advanced nonsmall cell lung carcinoma
F. Shepherd, J. Dancey, A. Arnold, A. Neville +4 more
2001Cancer137 citations Open access
Semantic Scholar
Phase I and pharmacokinetic study of daily oral AZD2171, an inhibitor of vascular endothelial growth factor tyrosine kinases, in combination with carboplatin and paclitaxel in patients with advanced non-small-cell lung cancer: the National Cancer Institute of Canada clinical trials group.
S. Laurie, I. Gauthier, A. Arnold, F. Shepherd +9 more
2008Journal of Clinical Oncology116 citations
Semantic Scholar
Randomised, double-blind trial of carboplatin and paclitaxel with daily oral cediranib or placebo in patients with advanced non-small cell lung cancer: NCIC Clinical Trials Group study BR29.
S. Laurie, B. Solomon, L. Seymour, Peter M. Ellis +15 more
2014European Journal of Cancer96 citations
Semantic Scholar
Chemotherapy induced amenorrhoea in a randomised trial of adjuvant chemotherapy duration in breast cancer.
L. Reyno, M. Levine, P. Skingley, A. Arnold +1 more
1992European Journal of Cancer62 citations
Semantic Scholar
Lessons learned from enrollment in the BEST study--a multicenter, randomized trial of group psychosocial support in metastatic breast cancer.
P. Goodwin, M. Leszcz, G. Quirt, J. Koopmans +5 more
2000Journal of Clinical Epidemiology60 citations
Semantic Scholar
Treatment-emergent hypertension and outcomes in patients with advanced non-small-cell lung cancer receiving chemotherapy with or without the vascular endothelial growth factor receptor inhibitor cediranib: NCIC Clinical Trials Group Study BR24.
R. Goodwin, Ke-Yue Ding, Lesley Seymour, A. Lemaître +11 more
2010Annals of Oncology53 citations Open access
Semantic Scholar
Addition of verapamil and tamoxifen to the initial chemotherapy of small cell lung cancer a phase I/II study
A. Figueredo, A. Arnold, M. Goodyear, B. Findlay +3 more
1990Cancer49 citations Open access
Semantic Scholar
Chemotherapy of advanced ovarian carcinoma: Initial experience using a platinum‐based combination
Christopher J. Williams, B. Mead, A. Arnold, J. Green +2 more
1982Cancer41 citations Open access
Semantic Scholar
A randomized placebo-controlled study of tamoxifen after adjuvant chemotherapy in premenopausal women with early breast cancer (National Cancer Institute of Canada--Clinical Trials Group Trial, MA.12).
V. Bramwell, K. Pritchard, D. Tu, K. Tonkin +7 more
2010Annals of Oncology39 citations Open access
Semantic Scholar
A phase I dose escalation study of the matrix metalloproteinase inhibitor BAY 12-9566 administered orally in patients with advanced solid tumours.
H. Hirte, R. Goel, P. Major, L. Seymour +10 more
2000Annals of Oncology34 citations Open access
Semantic Scholar
Offering a choice between two adjuvant chemotherapy regimens: a pilot study to develop a decision aid for women with breast cancer.
E. Irwin, A. Arnold, T. Whelan, L. Reyno +1 more
1999Patient Education and Counseling30 citations
Semantic Scholar
Lung cancer chemotherapy agents increase procoagulant activity via protein disulfide isomerase-dependent tissue factor decryption
Zakhar Lysov, L. Swystun, S. Kuruvilla, A. Arnold +1 more
2015Blood Coagulation and Fibrinolysis28 citations
Semantic Scholar
Patterns of failure following loco-regional radiotherapy in the treatment of limited stage small cell lung cancer.
P. Coy, D. Hodson, Nevin Murray, Joseph L. Peter +13 more
1994International Journal of Radiation Oncology, Biology, Physics27 citations
Semantic Scholar
Randomized phase II feasibility study of combining the matrix metalloproteinase inhibitor BMS-275291 with paclitaxel plus carboplatin in advanced non-small cell lung cancer.
J. Douillard, C. Peschel, F. Shepherd, L. Paz-Ares +11 more
2004Lung Cancer25 citations
Semantic Scholar
A qualitative study evaluating causality attribution for serious adverse events during early phase oncology clinical trials
S. Mukherjee, M. Coombes, Mitchell Levine, J. Cosby +2 more
2011Investigational new drugs23 citations
Semantic Scholar
Pharmacologic insights into the future of trastuzumab.
Brian Leyland-Jones, A. Arnold, K. Gelmon, S. Verma +5 more
2001Annals of Oncology23 citations Open access
Semantic Scholar
A phase I trial of high-dose paclitaxel, cyclophosphamide and mitoxantrone with autologous blood stem cell support for the treatment of metastatic breast cancer.
S. Glück, C. Germond, P. Lopez, P. Cano +5 more
1998European Journal of Cancer20 citations
Semantic Scholar
Phase II Trial of 13-cis-Retinoic Acid Plus Interferon α in Non-Small-Cell Lung CancerFor the National Cancer Instit ute of Canada Clinical Trials Group
A. Arnold, J. Ayoub, L. Douglas, P. Hoogendoorn +4 more
199420 citations
Semantic Scholar
Funding oncology clinical trials: are cooperative group trials sustainable?
H. Seow, P. Whelan, M. Levine, K. Cowan +5 more
2012Journal of Clinical Oncology18 citations
Semantic Scholar
Anticoagulation and Bleeding: A Pooled Analysis of Lung Cancer Trials of the NCIC Clinical Trials Group
A. le Maître, K. Ding, F. Shepherd, N. Leighl +2 more
2009Journal of Thoracic Oncology16 citations Open access
Semantic Scholar
Randomized phase II study of maintenance vandetanib (ZD6474) in small cell lung cancer (SCLC) patients who have a complete or partial response to induction therapy: NCIC CTG BR.20
A. Arnold, M. Smylie, K. Ding, Y. Ung +6 more
200713 citations
Semantic Scholar
Phase II Study of Troxacitabine (BCH-4556) in Patients with Advanced Non-Small-Cell Lung Cancer
S. Dent, A. Arnold, D. Stewart, S. Gertler +8 more
2005Lung9 citations
Semantic Scholar
Randomized phase II-III study of matrix metalloproteinase inhibitor (MMPI) BMS-275291 in combination with paclitaxel (P) and carboplatin (C) in advanced non-small cell lung cancer (NSCLC): NCIC-CTG BR.18.
N. Leighl, F. Shepherd, L. Paz-Ares, J. Douillard +6 more
2004Journal of Clinical Oncology8 citations
Semantic Scholar
Tamoxifen (T) compared to placebo (P), after adjuvant chemotherapy (CT), in premenopausal women with early breast cancer (EBC): Interim results of NCIC-CTG MA.12
V. Bramwell, K. Pritchard, D. Tu, K. Tonkin +6 more
20076 citations
Semantic Scholar
Randomised phase II study of BMS-275291 versus placebo in patients (pts) with stage IIIb or IV non small cell lung cancer (NSCLC) receiving paclitaxel + carboplatin (PC): National Cancer Institute of Canada clinical trials group (NCIC CTG) br.18
J. Douillard, V. Petersen, F. Shepherd, L. Paz-Ares +7 more
20015 citations
Semantic Scholar
Efficacy and safety of three-weekly herceptin with paclitaxel in women with her2-positive metastatic breast cancer: preliminary results of a phase II trial
S. Verma, B. Leyland-Jones, J. Ayoub, K. Gelmon +3 more
20013 citations
Semantic Scholar
Moving promising research findings to the clinic: Methodological issues in the design and conduct of clinical trials of retinoids
A. Arnold
1997International Journal of Cancer3 citations Open access
Semantic Scholar
234 Importance of timing for thoracic irradiation (TI) in the combined modality treatment of limited-stage small-cell lung cancer (LSCLC): An update of the National Cancer Institute of Canada (NCIC) BR6 study
N. Murray, B. Zee, J. Pater, Peter Coy +13 more
19973 citations
Semantic Scholar
Delays in diagnosis and initiating treatment for patients with lung cancer.
R. Vandermeer, S. Dimitry, A. Arnold, Peter M. Ellis
2006Journal of Clinical Oncology2 citations
Semantic Scholar
The effect of doxycycline on bone turnover and tumor markers in breast cancer (BC) patients with skeletal metastases
S. Dhesy-Thind, J. Julian, R. Tozer, P. Ellis +3 more
20052 citations
Semantic Scholar
Phase II trial of 13-cis-retinoic acid plus interferon alpha in non-small-cell lung cancer. The National Cancer Institute of Canada Clinical Trials Group.
A. Arnold, J. Ayoub, L. Douglas, P. Hoogendoorn +4 more
1994Journal of the National Cancer Institute2 citations
Semantic Scholar
A tool for assessing adverse events in phase I/II oncology clinical trials
M. Coombes, S. Mukherjee, B. Kowaleski, M. Levine +2 more
20071 citations
Semantic Scholar
92 POSTER Effects of AZD2171 on pharmacokinetics (PK) of carboplatin (C) and paclitaxel (P) in patients with advanced non-small cell lung cancer (NSCLC): a study of the National Cancer Institute of Canada Clinical Trials Group
E. Chen, W. Zhang, S. Lauri, A. Arnold +6 more
20061 citations
Semantic Scholar
P-936 Use of an algorithm to aid determination of causality in early clinical trials of lung cancer using targeted therapy
A. Arnold, B. Kowaleski, J. Watts
20051 citations
Semantic Scholar
Phase II trial of MTA (AlimtaTM) and cisplatin in patients with advanced Non-Small Cell Lung Cancer (NSCLC)
F. Shepherd, A. Arnold, A. Neville, J. Dancey +3 more
20001 citations
Semantic Scholar
MA 10.01 Durvalumab ± Tremelimumab with Platinum-Doublets in Non-Small Cell Lung Cancer: Canadian Cancer Trials Group Study IND.226
R. Juergens, D. Hao, S. Laurie, P. Ellis +12 more
20170 citations Open access
Semantic Scholar
Abstract 580: Lung Cancer Chemotherapy Agents Increase Procoagulant Activity via Protein Disulfide Isomerase-Dependent Tissue Factor Decryption
Zakhar Lysov, L. Swystun, S. Kuruvilla, A. Arnold +3 more
2014Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar
Lung Cancer Chemotherapy Agents Increase Procoagulant Activity In Vitro and In Vivo
Zakhar Lysov, L. Swystun, S. Kuruvilla, A. Arnold +1 more
20110 citations
Semantic Scholar

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F. Shepherd — researcher profile on SciRah
L. Seymour×13
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D. Tu×7
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D. Tu — researcher profile on SciRah
G. Goss×7
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P. Ellis — researcher profile on SciRah

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S. Laurie — researcher profile on SciRah

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K. Ding — researcher profile on SciRah

K. Pritchard×4

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K. Pritchard — researcher profile on SciRah

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B. Findlay — researcher profile on SciRah

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K. Gelmon — researcher profile on SciRah

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N. Leighl — researcher profile on SciRah

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L. Paz-Ares — researcher profile on SciRah