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C. Bařinka · SciRah

Researcher profile · Semantic Scholar

C. Bařinka

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C. Bařinka — researcher profile on SciRah

h-index: 37
Works: 184
Citations: 4,296

Most-cited papers

Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells
Tessa Knox, Eva Sahakian, Debarati Banik, M. Hadley +13 more
2019Scientific Reports156 citations Open access
Semantic Scholar
Histone Deacetylase 11 Is a Fatty-Acid Deacylase.
Z. Kutil, Z. Nováková, Marat Meleshin, J. Mikesova +2 more
2018ACS Chemical Biology146 citations Open access
Semantic Scholar
Glu-Ureido–Based Inhibitors of Prostate-Specific Membrane Antigen: Lessons Learned During the Development of a Novel Class of Low-Molecular-Weight Theranostic Radiotracers
K. Kopka, M. Benešová, C. Bařinka, U. Haberkorn +1 more
2017Journal of Nuclear Medicine139 citations Open access
Semantic Scholar
Development of Multi-Functional Histone Deacetylase 6 Degraders with Potent Anti-Myeloma Activity.
Hao Wu, Ka Yang, Zhong-Rui Zhang, Eric D. Leisten +7 more
2019Journal of Medicinal Chemistry126 citations Open access
Semantic Scholar
Mitochondria-adaptor TRAK1 promotes kinesin-1 driven transport in crowded environments
Verena Henrichs, L. Grycova, C. Bařinka, Zuzana Nahacka +5 more
2020Nature Communications74 citations Open access
Semantic Scholar
Human histone deacetylase 6 shows strong preference for tubulin dimers over assembled microtubules
Ľ. Škultétyová, K. Ustinova, Z. Kutil, Z. Nováková +8 more
2017Scientific Reports74 citations Open access
Semantic Scholar
Structural and in Vivo Characterization of Tubastatin A, a Widely Used Histone Deacetylase 6 Inhibitor.
S. Shen, M. Svoboda, Guang-Ming Zhang, M. Cavasin +5 more
2020ACS Medicinal Chemistry Letters69 citations Open access
Semantic Scholar
Prostate-specific membrane antigen (PSMA)-mediated laminin proteolysis generates a pro-angiogenic peptide
Rebecca E. Conway, Camilo Rojas, J. Alt, Z. Nováková +11 more
2016Angiogenesis67 citations
Semantic Scholar
Brain Penetrable Histone Deacetylase 6 Inhibitor SW-100 Ameliorates Memory and Learning Impairments in a Mouse Model of Fragile X Syndrome
A. Kozikowski, S. Shen, M. Pardo, M. T. Tavares +10 more
2018ACS Chemical Neuroscience65 citations Open access
Semantic Scholar
Uncovering Robust Delactoylase and Depyruvoylase Activities of HDAC Isoforms.
Matthes Zessin, Marat Meleshin, Lucas Praetorius, W. Sippl +2 more
2022ACS Chemical Biology63 citations
Semantic Scholar
Discovery of a New Isoxazole-3-hydroxamate Based Histone Deacetylase 6 Inhibitor SS-208 with Anti-tumor Activity in Syngeneic Melanoma Mouse Models.
S. Shen, M. Hadley, K. Ustinova, J. Pavlicek +9 more
2019Journal of Medicinal Chemistry63 citations Open access
Semantic Scholar
A prostate-specific membrane antigen activated molecular rotor for real-time fluorescence imaging
Jing-Ming Zhang, A. Rakhimbekova, Xiaojiang Duan, Qingqing Yin +13 more
2021Nature Communications59 citations Open access
Semantic Scholar
Rational Design of Suprastat, a Novel Selective Histone Deacetylase 6 Inhibitor with the Ability to Potentiate Immunotherapy in Melanoma Models.
S. Noonepalle, S. Shen, J. Ptacek, M. T. Tavares +9 more
2020Journal of Medicinal Chemistry46 citations Open access
Semantic Scholar
Mitochondrial respiration supports autophagy to provide stress resistance during quiescence
Sílvia Magalhães‐Novais, J. Blecha, Ravindra Naraine, J. Mikesova +21 more
2022Autophagy42 citations Open access
Semantic Scholar
The disordered N-terminus of HDAC6 is a microtubule-binding domain critical for efficient tubulin deacetylation
K. Ustinova, Z. Nováková, M. Saito, Marat Meleshin +7 more
2020Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Synthesis, Molecular Docking and Biological Characterization of Pyrazine Linked 2-Aminobenzamides as New Class I Selective Histone Deacetylase (HDAC) Inhibitors with Anti-Leukemic Activity
Hany S. Ibrahim, M. Abdelsalam, Yanira Zeyn, Matthes Zessin +14 more
2021International Journal of Molecular Sciences37 citations Open access
Semantic Scholar
Selection and characterization of Anticalins targeting human prostate-specific membrane antigen (PSMA).
C. Bařinka, J. Ptacek, Antonia Richter, Z. Nováková +2 more
2016Protein engineering, design & selection : PEDS37 citations
Semantic Scholar
Continuous Activity Assay for HDAC11 Enabling Reevaluation of HDAC Inhibitors
Z. Kutil, J. Mikesova, Matthes Zessin, Marat Meleshin +6 more
2019ACS Omega35 citations Open access
Semantic Scholar
Design and Synthesis of Mercaptoacetamides as Potent, Selective, and Brain Permeable Histone Deacetylase 6 Inhibitors.
Wei-Ke Lv, Guang-Ming Zhang, C. Bařinka, J. Eubanks +1 more
2017ACS Medicinal Chemistry Letters35 citations Open access
Semantic Scholar
Development of PSMA-1007 - Related Series of 18F-Labeled Glu-ureido type PSMA inhibitors.
J. Cardinale, M. Roscher, Martin Schäfer, M. Geerlings +9 more
2020Journal of Medicinal Chemistry34 citations
Semantic Scholar
Novel Monoclonal Antibodies Recognizing Human Prostate-Specific Membrane Antigen (PSMA) as Research and Theranostic Tools
Z. Nováková, C. Foss, Ben T. Copeland, V. Morath +5 more
2017The Prostate34 citations Open access
Semantic Scholar
Structure–Activity Relationship of 18F-Labeled Phosphoramidate Peptidomimetic Prostate-Specific Membrane Antigen (PSMA)-Targeted Inhibitor Analogues for PET Imaging of Prostate Cancer
Shorouk Dannoon, T. Ganguly, Hendry Cahaya, Jonathan J. Geruntho +13 more
2016Journal of Medicinal Chemistry31 citations Open access
Semantic Scholar
One-Atom-Substitution Enables Direct and Continuous Monitoring of Histone Deacylase Activity.
Matthes Zessin, Z. Kutil, Marat Meleshin, Z. Nováková +7 more
2019Biochemistry30 citations
Semantic Scholar
The unraveling of substrate specificity of histone deacetylase 6 domains using acetylome peptide microarrays and peptide libraries
Z. Kutil, Ľ. Škultétyová, D. Rauh, Marat Meleshin +10 more
2018The FASEB Journal30 citations Open access
Semantic Scholar
Tetrahydroquinoline-Capped Histone Deacetylase 6 Inhibitor SW-101 Ameliorates Pathological Phenotypes in a Charcot-Marie-Tooth Type 2A Mouse Model.
S. Shen, Cristina Picci, K. Ustinova, V. Benoy +10 more
2021Journal of Medicinal Chemistry28 citations Open access
Semantic Scholar
Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells
J. Ptacek, I. Šnajdr, J. Schimer, Z. Kutil +7 more
2023International Journal of Molecular Sciences27 citations Open access
Semantic Scholar
Author Correction: Selective HDAC6 inhibitors improve anti-PD-1 immune checkpoint blockade therapy by decreasing the anti-inflammatory phenotype of macrophages and down-regulation of immunosuppressive proteins in tumor cells
Tessa Knox, Eva Sahakian, Debarati Banik, M. Hadley +13 more
2019Scientific Reports27 citations Open access
Semantic Scholar
Molecular Basis for the Selective Inhibition of Histone Deacetylase 6 by a Mercaptoacetamide Inhibitor.
N. J. Porter, S. Shen, C. Bařinka, A. Kozikowski +1 more
2018ACS Medicinal Chemistry Letters27 citations Open access
Semantic Scholar
Discovery of a para-Acetoxy-benzyl Ester Prodrug of a Hydroxamate-Based Glutamate Carboxypeptidase II Inhibitor as Oral Therapy for Neuropathic Pain
R. Rais, J. Vávra, T. Tichý, Ranjeet P. Dash +12 more
2017Journal of Medicinal Chemistry27 citations Open access
Semantic Scholar
Development of 5D3-DM1: A Novel Anti-Prostate-Specific Membrane Antigen Antibody-Drug Conjugate for PSMA-Positive Prostate Cancer Therapy
Colin T Huang, Xin Guo, C. Bařinka, Shawn E Lupold +5 more
2020Molecular Pharmaceutics26 citations Open access
Semantic Scholar
Structural basis of prostate-specific membrane antigen recognition by the A9g RNA aptamer
J. Ptacek, Dong Zhang, Liming Qiu, Sven Kruspe +10 more
2020Nucleic Acids Research26 citations Open access
Semantic Scholar
Evaluation of 111In-DOTA-5D3, a Surrogate SPECT Imaging Agent for Radioimmunotherapy of Prostate-Specific Membrane Antigen
S. Banerjee, Vivek Kumar, A. Lisok, D. Plyku +6 more
2018Journal of Nuclear Medicine26 citations Open access
Semantic Scholar
Design of composite inhibitors targeting glutamate carboxypeptidase II: the importance of effector functionalities
Z. Nováková, J. Černý, Cindy J. Choy, J. Nedrow +4 more
2015The FEBS Journal26 citations Open access
Semantic Scholar
Comparative Structure-Based Virtual Screening Utilizing Optimized AlphaFold Model Identifies Selective HDAC11 Inhibitor
Fady Baselious, Sebastian Hilscher, D. Robaa, C. Bařinka +2 more
2024International Journal of Molecular Sciences24 citations Open access
Semantic Scholar
BRAT1 links Integrator and defective RNA processing with neurodegeneration
Zuzana Cihlarova, J. Kubovčiak, M. Sobol, K. Krejcikova +7 more
2022Nature Communications24 citations Open access
Semantic Scholar
Cellular Delivery of Bioorthogonal Pretargeting Therapeutics in PSMA-Positive Prostate Cancer
S. Hapuarachchige, Colin T Huang, Madeline C. Donnelly, C. Bařinka +3 more
2019Molecular Pharmaceutics22 citations Open access
Semantic Scholar
Structural and computational basis for potent inhibition of glutamate carboxypeptidase II by carbamate-based inhibitors
C. Bařinka, Z. Nováková, Niyada Hin, Daniel Bím +11 more
2018Bioorganic & Medicinal Chemistry22 citations Open access
Semantic Scholar
Synthesis and Pharmacological Evaluation of Selective Histone Deacetylase 6 Inhibitors in Melanoma Models.
M. T. Tavares, S. Shen, Tessa Knox, M. Hadley +4 more
2017ACS Medicinal Chemistry Letters21 citations Open access
Semantic Scholar
Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity.
Z. Nováková, K. Wozniak, A. Jančařík, R. Rais +12 more
2016Journal of Medicinal Chemistry20 citations Open access
Semantic Scholar
Carborane-containing urea-based inhibitors of glutamate carboxypeptidase II: Synthesis and structural characterization.
S. Youn, Kyung Im Kim, J. Ptacek, Kiwon Ok +5 more
2015Bioorganic & Medicinal Chemistry Letters19 citations
Semantic Scholar
Predicting Effects of Site-Directed Mutagenesis on Enzyme Kinetics by QM/MM and QM Calculations: A Case of Glutamate Carboxypeptidase II.
Daniel Bím, M. Navrátil, Ondrej Gutten, J. Konvalinka +6 more
2022Journal of Physical Chemistry B18 citations Open access
Semantic Scholar
Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6)
L. Motlová, I. Šnajdr, Z. Kutil, Erik Andris +11 more
2023ACS Chemical Biology14 citations Open access
Semantic Scholar
The Avian Retroviral Receptor Tva Mediates the Uptake of Transcobalamin Bound Vitamin B12 (Cobalamin)
Veronika Krchlíková, J. Mikesova, J. Geryk, C. Bařinka +7 more
2021Journal of Virology14 citations Open access
Semantic Scholar
Targeting Prostate Cancer Using Bispecific T-Cell Engagers against Prostate-Specific Membrane Antigen
Gargi Das, J. Ptacek, Barbora Havlínová, J. Nedvědová +2 more
2023ACS Pharmacology & Translational Science11 citations Open access
Semantic Scholar
SART3 associates with a post-splicing complex.
K. Klimešová, Hana Petržílková, C. Bařinka, D. Staněk
2023Journal of Cell Science10 citations Open access
Semantic Scholar
Continuous Fluorescent Sirtuin Activity Assay Based on Fatty Acylated Lysines
Matthes Zessin, Marat Meleshin, Sebastian Hilscher, C. Schiene-Fischer +3 more
2023International Journal of Molecular Sciences10 citations Open access
Semantic Scholar
Efficient allele conversion in mouse zygotes and primary cells based on electroporation of Cre protein.
Irena Jenickova, P. Kašpárek, Silvia Petrezsélyová, J. Eliáš +5 more
2020Methods10 citations
Semantic Scholar
2-Aminoadipic Acid-C(O)-Glutamate Based Prostate-Specific Membrane Antigen Ligands for Potential Use as Theranostics.
R. Nakajima, Z. Nováková, W. Tueckmantel, L. Motlová +2 more
2018ACS Medicinal Chemistry Letters10 citations Open access
Semantic Scholar
Glycoforms of human prostate-specific membrane antigen (PSMA) in human cells and prostate tissue
Wei Yuan, Bao-Qin Liu, M. Sanda, Renhuizi Wei +4 more
2021The Prostate9 citations Open access
Semantic Scholar
Novel β- and γ-amino acid derived inhibitors of prostate-specific membrane antigen.
Kyul Kim, Hongmok Kwon, C. Bařinka, L. Motlová +10 more
2020Journal of Medicinal Chemistry9 citations Open access
Semantic Scholar

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Z. Nováková×21
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A. Kozikowski×14
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