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J. Dimitrov · SciRah

Researcher profile · Semantic Scholar

J. Dimitrov

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J. Dimitrov — researcher profile on SciRah

h-index: 35
Works: 151
Citations: 3,902

Most-cited papers

Complement activation by heme as a secondary hit for atypical hemolytic uremic syndrome.
Marie Frimat, Fanny Tabarin, J. Dimitrov, C. Poitou +3 more
2013Blood254 citations Open access
Semantic Scholar
Molecular basis for bacterial peptidoglycan recognition by LysM domains
S. Mesnage, M. Dellarole, N. J. Baxter, Jean-Baptiste Rouget +8 more
2014Nature Communications200 citations Open access
Semantic Scholar
Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles.
N. Merle, Anne Grunenwald, Helena Rajaratnam, V. Gnemmi +22 more
2018JCI Insight164 citations Open access
Semantic Scholar
Heme: Modulator of Plasma Systems in Hemolytic Diseases.
L. Roumenina, J. Rayes, S. Lacroix-Desmazes, J. Dimitrov
2016Trends in Molecular Medicine136 citations
Semantic Scholar
Antibody Polyreactivity in Health and Disease: Statu Variabilis
J. Dimitrov, Cyril Planchais, L. Roumenina, T. Vassilev +2 more
2013Journal of Immunology110 citations Open access
Semantic Scholar
P-selectin drives complement attack on endothelium during intravascular hemolysis in TLR-4/heme-dependent manner
N. Merle, R. Paule, J. Léon, Marie Daugan +6 more
2019Proceedings of the National Academy of Sciences of the United States of America105 citations Open access
Semantic Scholar
Natural Antibodies: from First-Line Defense Against Pathogens to Perpetual Immune Homeostasis
M. Maddur, S. Lacroix-Desmazes, J. Dimitrov, M. Kazatchkine +2 more
2019Clinical reviews in allergy and immunology95 citations Open access
Semantic Scholar
The interaction between factor H and VWF increases factor H cofactor activity and regulates VWF prothrombotic status.
Julie Rayes, L. Roumenina, J. Dimitrov, Y. Repessé +8 more
2014Blood76 citations
Semantic Scholar
Heme induces human and mouse platelet activation through C-type-lectin-like receptor-2
Joshua H. Bourne, M. Colicchia, Ying Di, Eleyna M. Martin +5 more
2020Haematologica74 citations Open access
Semantic Scholar
Conformational Plasticity in Broadly Neutralizing HIV-1 Antibodies Triggers Polyreactivity
Julie Prigent, Annaelle Jarossay, C. Planchais, C. Eden +11 more
2018Cell Reports64 citations Open access
Semantic Scholar
Potent human broadly SARS-CoV-2–neutralizing IgA and IgG antibodies effective against Omicron BA.1 and BA.2
C. Planchais, Ignacio Fernández, T. Bruel, G. D. de Melo +28 more
2022bioRxiv62 citations Open access
Semantic Scholar
Breaking the law: unconventional strategies for antibody diversification
Alexia Kanyavuz, Annaelle Marey-Jarossay, S. Lacroix-Desmazes, J. Dimitrov
2019Nature reviews. Immunology60 citations Open access
Semantic Scholar
Potent human broadly neutralizing antibodies to hepatitis B virus from natural controllers
Verena Hehle, Maxime Beretta, M. Bourgine, M. Ait-goughoulte +16 more
2020Journal of Experimental Medicine54 citations Open access
Semantic Scholar
Characterization of Renal Injury and Inflammation in an Experimental Model of Intravascular Hemolysis
N. Merle, Anne Grunenwald, M. Figueres, S. Chauvet +17 more
2018Frontiers in Immunology53 citations Open access
Semantic Scholar
Impact of Antigen Density on the Binding Mechanism of IgG Antibodies
Maya Hadzhieva, A. Pashov, S. Kaveri, S. Lacroix-Desmazes +2 more
2017Scientific Reports51 citations Open access
Semantic Scholar
Functional Characterization of Autoantibodies against Complement Component C3 in Patients with Lupus Nephritis*
V. Vasilev, Rémi Noé, M. Dragon-Durey, S. Chauvet +5 more
2015Journal of Biological Chemistry51 citations Open access
Semantic Scholar
Regulation of immune responses to protein therapeutics by transplacental induction of T cell tolerance
N. Gupta, S. Culina, Y. Meslier, J. Dimitrov +11 more
2015Science Translational Medicine48 citations
Semantic Scholar
Intravenous immunoglobulin induces IL-4 in human basophils by signaling through surface-bound IgE.
C. Galeotti, Emmanuel Stephen-Victor, A. Karnam, Mrinmoy Das +10 more
2019Journal of Allergy and Clinical Immunology46 citations Open access
Semantic Scholar
Heme Drives Susceptibility of Glomerular Endothelium to Complement Overactivation Due to Inefficient Upregulation of Heme Oxygenase-1
Olivia May, N. Merle, Anne Grunenwald, V. Gnemmi +13 more
2018Frontiers in Immunology44 citations Open access
Semantic Scholar
Sequence features of variable region determining physicochemical properties and polyreactivity of therapeutic antibodies.
M. Lecerf, Alexia Kanyavuz, S. Lacroix-Desmazes, J. Dimitrov
2019Molecular Immunology42 citations Open access
Semantic Scholar
Development of inhibitory antibodies to therapeutic factor VIII in severe hemophilia A is associated with microsatellite polymorphisms in the HMOX1 promoter
Y. Repessé, I. Peyron, J. Dimitrov, S. Dasgupta +11 more
2013Haematologica41 citations Open access
Semantic Scholar
Heme Interferes With Complement Factor I-Dependent Regulation by Enhancing Alternative Pathway Activation
A. Gerogianni, J. Dimitrov, A. Zarantonello, Victoria Poillerat +8 more
2022Frontiers in Immunology29 citations Open access
Semantic Scholar
Materno-Fetal Transfer of Preproinsulin Through the Neonatal Fc Receptor Prevents Autoimmune Diabetes
Slobodan Culina, N. Gupta, Raphael Boisgard, G. Afonso +11 more
2015Diabetes29 citations Open access
Semantic Scholar
Noncanonical Functions of Antibodies.
J. Dimitrov, S. Lacroix-Desmazes
2020Trends in immunology28 citations Open access
Semantic Scholar
Prevalence and Gene Characteristics of Antibodies with Cofactor-induced HIV-1 Specificity*
M. Lecerf, Tobias Scheel, A. Pashov, Annaelle Jarossay +7 more
2015Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Antibody-mediated catalysis: induction and therapeutic relevance.
Ankit Mahendra, Meenu Sharma, D. Rao, I. Peyron +4 more
2013Autoimmunity Reviews28 citations
Semantic Scholar
Anti-V1/V3-glycan broadly HIV-1 neutralizing antibodies in a post-treatment controller.
L. M. Molinos-Albert, E. Baquero, M. Bouvin-Pley, V. Lorin +12 more
2023Cell Host and Microbe27 citations Open access
Semantic Scholar
The receptor for advanced glycation end products is a sensor for cell‐free heme
Olivia May, L. Yatime, N. Merle, Florian Delguste +10 more
2020The FEBS Journal27 citations Open access
Semantic Scholar
HIV-1 Envelope Recognition by Polyreactive and Cross-Reactive Intestinal B Cells
C. Planchais, Ayrin Kök, Alexia Kanyavuz, V. Lorin +12 more
2019Cell Reports27 citations Open access
Semantic Scholar
Epitope convergence of broadly HIV-1 neutralizing IgA and IgG antibody lineages in a viremic controller
V. Lorin, Ignacio Fernández, Guillemette Masse-Ranson, M. Bouvin-Pley +20 more
2022Journal of Experimental Medicine23 citations Open access
Semantic Scholar
Relevance of the Materno-Fetal Interface for the Induction of Antigen-Specific Immune Tolerance
Angelina Mimoun, S. Delignat, I. Peyron, V. Daventure +5 more
2020Frontiers in Immunology23 citations Open access
Semantic Scholar
A Cryptic Polyreactive Antibody Recognizes Distinct Clades of HIV-1 Glycoprotein 120 by an Identical Binding Mechanism*
J. Dimitrov, Cyril Planchais, Tobias Scheel, Delphine Ohayon +4 more
2014Journal of Biological Chemistry21 citations Open access
Semantic Scholar
Longitudinal and Integrative Biomodeling of Effector and Memory Immune Compartments after Inactivated Influenza Vaccination
O. Bonduelle, Nora Yahia, S. Sibéril, N. Benhabilès +19 more
2013Journal of Immunology21 citations Open access
Semantic Scholar
Intravenous Immunoglobulin with Enhanced Polyspecificity Improves Survival in Experimental Sepsis and Aseptic Systemic Inflammatory Response Syndromes
I. Djoumerska-Alexieva, L. Roumenina, A. Pashov, J. Dimitrov +15 more
2015Molecular Medicine20 citations Open access
Semantic Scholar
Mechanism and functional implications of the heme-induced binding promiscuity of IgE.
Maya Hadzhieva, T. Vassilev, L. Roumenina, J. Bayry +3 more
2015Biochemistry19 citations
Semantic Scholar
Neutralization of Japanese Encephalitis Virus by heme-induced broadly reactive human monoclonal antibody
N. Gupta, M. de Wispelaere, M. Lecerf, Manjula Kalia +7 more
2015Scientific Reports19 citations Open access
Semantic Scholar
Heme oxygenase-1 is dispensable for the anti-inflammatory activity of intravenous immunoglobulin
C. Galeotti, P. Hegde, Mrinmoy Das, Emmanuel Stephen-Victor +6 more
2016Scientific Reports18 citations Open access
Semantic Scholar
Thermodynamic stability contributes to immunoglobulin specificity.
J. Dimitrov, S. Kaveri, S. Lacroix-Desmazes
2014TIBS -Trends in Biochemical Sciences. Regular ed16 citations
Semantic Scholar
Polyreactivity of antibodies from different B-cell subpopulations is determined by distinct sequence patterns of variable region
M. Lecerf, Robin V. Lacombe, J. Dimitrov
2023bioRxiv15 citations Open access
Semantic Scholar
Assessment of the breadth of binding promiscuity of heme towards human proteins
L. Roumenina, J. Dimitrov
2022Biological chemistry15 citations Open access
Semantic Scholar
Interaction of clinical-stage antibodies with heme predicts their physiochemical and binding qualities
M. Lecerf, Alexia Kanyavuz, S. Rossini, J. Dimitrov
2020Communications Biology15 citations Open access
Semantic Scholar
Potential Predictive Role of Lipid Peroxidation Markers for Type 2 Diabetes in the Adult Tunisian Population.
Houda Bouhajja, F. Kacem, R. Abdelhedi, Marwa Ncir +10 more
2017Canadian Journal of Diabetes15 citations
Semantic Scholar
Use of cysteine as a spectroscopic probe for determination of heme-scavenging capacity of serum proteins and whole human serum.
Rémi Noé, Nina Božinović, M. Lecerf, S. Lacroix-Desmazes +1 more
2019Journal of Pharmaceutical and Biomedical Analysis14 citations Open access
Semantic Scholar
Haemarthrosis and arthropathy do not favour the development of factor VIII inhibitors in severe haemophilia A mice
I. Peyron, J. Dimitrov, S. Delignat, B. Gangadharan +3 more
2015Haemophilia14 citations
Semantic Scholar
Predictive immunogenicity of Refacto® AF
S. Delignat, Y. Repessé, L. Gilardin, J. Dimitrov +3 more
2014Haemophilia14 citations
Semantic Scholar
Anti-IgE IgG autoantibodies isolated from therapeutic normal IgG intravenous immunoglobulin induce basophil activation
C. Galeotti, A. Karnam, J. Dimitrov, A. Chevailler +2 more
2019Cellular & Molecular Immunology13 citations Open access
Semantic Scholar
V Region of IgG Controls the Molecular Properties of the Binding Site for Neonatal Fc Receptor
S. Rossini, Rémi Noé, V. Daventure, M. Lecerf +2 more
2020Journal of Immunology12 citations Open access
Semantic Scholar
Anti-inflammatory activity of intravenous immunoglobulin through scavenging of heme
Marie Wiatr, N. Merle, I. Boudhabhay, Victoria Poillerat +6 more
2019Molecular Immunology11 citations Open access
Semantic Scholar
Cryptic polyreactivity of IgG expressed by splenic marginal zone B-cell lymphoma.
Ankit Mahendra, B. Gangadharan, S. André, Myriam Boudjoghra +6 more
2014Molecular Immunology11 citations
Semantic Scholar
HIV-1 treatment timing shapes the human intestinal memory B-cell repertoire to commensal bacteria
C. Planchais, L. M. Molinos-Albert, Pierre Rosenbaum, Thierry Hieu +8 more
2023Nature Communications10 citations Open access
Semantic Scholar

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