Researcher profile · Semantic Scholar

Zacharias Orfanos

h-index: 14
Works: 21
Citations: 574

Most-cited papers

Aciculin interacts with filamin C and Xin and is essential for myofibril assembly, remodeling and maintenance
Sibylle Molt, John B. Bührdel, S. Yakovlev, Peter Schein +9 more
2014Journal of Cell Science69 citations Open access
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The cochaperone BAG3 coordinates protein synthesis and autophagy under mechanical strain through spatial regulation of mTORC1.
Barbara Kathage, S. Gehlert, Anna Ulbricht, Laura Lüdecke +8 more
2017Biochimica et biophysica acta. Molecular cell research68 citations Open access
Semantic Scholar
Myofibrillar instability exacerbated by acute exercise in filaminopathy.
F. Chevessier, Julia Schuld, Zacharias Orfanos, Anne-Christine Plank +12 more
2015Human Molecular Genetics67 citations
Semantic Scholar
Breaking sarcomeres by in vitro exercise
Zacharias Orfanos, Markus P. O. Gödderz, E. Soroka, Tobias Gödderz +4 more
2016Scientific Reports53 citations Open access
Semantic Scholar
DAAM Is Required for Thin Filament Formation and Sarcomerogenesis during Muscle Development in Drosophila
Imre Molnár, E. Migh, Szilárd Szikora, T. Kalmár +11 more
2014PLoS Genetics44 citations Open access
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Identification of Xin-repeat proteins as novel ligands of the SH3 domains of nebulin and nebulette and analysis of their interaction during myofibril formation and remodeling
Stefan Eulitz, F. Sauer, M. Pelissier, P. Boisguérin +9 more
2013Molecular Biology of the Cell41 citations Open access
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Myosin isoform switching during assembly of the Drosophila flight muscle thick filament lattice
Zacharias Orfanos, J. Sparrow
2013Journal of Cell Science39 citations
Semantic Scholar
Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation
Julia Schuld, Zacharias Orfanos, F. Chevessier, B. Eggers +10 more
2020Acta Neuropathologica Communications35 citations Open access
Semantic Scholar
Sallimus and the dynamics of sarcomere assembly in Drosophila flight muscles.
Zacharias Orfanos, K. Leonard, Christopher Elliott, Anja Katzemich +2 more
2015Journal of Molecular Biology34 citations
Semantic Scholar
CCR2 Deficiency Impairs Ly6Clo and Ly6Chi Monocyte Responses in Orientia tsutsugamushi Infection
M. Petermann, Zacharias Orfanos, J. Sellau, Mohammad H. Gharaibeh +3 more
2021Frontiers in Immunology24 citations Open access
Semantic Scholar
A new early-onset neuromuscular disorder associated with kyphoscoliosis peptidase (KY) deficiency
C. Hedberg-Oldfors, N. Darin, M. Engman, Zacharias Orfanos +3 more
2016European Journal of Human Genetics23 citations Open access
Semantic Scholar
Myopodin is an F-actin bundling protein with multiple independent actin-binding regions
Anja Linnemann, Padmanabhan Vakeel, Eduardo Bezerra, Zacharias Orfanos +4 more
2012Journal of Muscle Research and Cell Motility20 citations
Semantic Scholar
FLNC-Associated Myofibrillar Myopathy
R. Kley, Yvonne Leber, B. Schrank, H. Zhuge +13 more
2021Neurology: Genetics16 citations Open access
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Xin‐deficient mice display myopathy, impaired contractility, attenuated muscle repair and altered satellite cell functionality
Dhuha Al-Sajee, Aliyah A. Nissar, Samantha K. Coleman, Irena A. Rebalka +5 more
2015Acta Physiologica16 citations
Semantic Scholar
Sarcomeric lesions and remodeling proximal to intercalated disks in overload-induced cardiac hypertrophy.
S. Kebir, Zacharias Orfanos, Julia Schuld, M. Linhart +6 more
2016Experimental Cell Research12 citations
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Transgenic tools for Drosophila muscle research
Zacharias Orfanos
2009Journal of Muscle Research and Cell Motility12 citations
Semantic Scholar
Myo fi brillar instability exacerbated by acute exercise in fi laminopathy
F. Chevessier, Julia Schuld, Zacharias Orfanos, Anne-Christine Plank +13 more
20152 citations
Semantic Scholar
Orientia tsutsugamushi binds to multiple C-type lectin receptors
Véronique Hefter, S. Mayer-Lambertz, Zacharias Orfanos, Jonas Mehl +2 more
2026Infection and Immunity1 citations Open access
Semantic Scholar
Homozygous expression of the myofibrillar myopathy-associated p.W2710X filamin C variant reveals major pathomechanisms of sarcomeric lesion formation
Julia Schuld, Zacharias Orfanos, F. Chevessier, B. Eggers +10 more
2020Acta Neuropathologica Communications0 citations Open access
Semantic Scholar
Sarkomerische Pathologie durch die homozygote Expression der Myofibrilläre Myopathie-assoziierten W2711X Filamin-C Mutante
Julia Schuld, Zacharias Orfanos, F. Chevessier, B. Eggers +8 more
2019Nervenheilkunde0 citations
Semantic Scholar
P.78Sarcomeric pathology induced by homozygous expression of the myofibrillar myopathy - associated p.W2711X filamin C mutant
Julia Schuld, Zacharias Orfanos, F. Chevessier, A. Unger +6 more
2019Neuromuscular Disorders0 citations
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F. Chevessier

×6

A. Unger×6

W. Linke×6

R. Schröder×6

R. Kley×4

B. Eggers×4

C. Clemen×4

K. Marcus×3